{"id":"https://openalex.org/W1997462178","doi":"https://doi.org/10.1097/00000658-200104000-00012","title":"Anabolic Effects of Oxandrolone After Severe Burn","display_name":"Anabolic Effects of Oxandrolone After Severe Burn","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W1997462178","doi":"https://doi.org/10.1097/00000658-200104000-00012","mag":"1997462178","pmid":"https://pubmed.ncbi.nlm.nih.gov/11303139","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1421286"},"language":"en","primary_location":{"id":"doi:10.1097/00000658-200104000-00012","doi":"https://doi.org/10.1097/00000658-200104000-00012","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000658-200104000-00012","pdf_url":null,"source":{"id":"https://openalex.org/S157664895","display_name":"Annals of Surgery","issn_l":"0003-4932","issn":["0003-4932","1528-1140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgery","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1997462178"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1421286/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112393202","display_name":"David W. Hart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801713311","display_name":"Shriners Hospitals for Children - Galveston","ror":"https://ror.org/01v95tx09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801713311","https://openalex.org/I4210144267"]},{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David W. Hart","raw_affiliation_strings":["Department of Surgery, The University of Texas Medical Branch and the Shriners Hospitals for Children, Galveston, Texas, USA","Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, The University of Texas Medical Branch and the Shriners Hospitals for Children, Galveston, Texas, USA","institution_ids":["https://openalex.org/I2801713311","https://openalex.org/I55302922"]},{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041106533","display_name":"Steven E. Wolf","orcid":"https://orcid.org/0000-0003-2972-3440","observed_orcids":["https://orcid.org/0000-0003-2972-3440"]},"institutions":[{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Steven E. Wolf","raw_affiliation_strings":["Shriners Hospitals for Children"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shriners Hospitals for Children","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045741117","display_name":"Peter I. Ramzy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter I. Ramzy","raw_affiliation_strings":["Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088819443","display_name":"David L. Chinkes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David L. Chinkes","raw_affiliation_strings":["Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087352178","display_name":"Robert B. Beauford","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert B. Beauford","raw_affiliation_strings":["Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055903272","display_name":"Arny A. Ferrando","orcid":"https://orcid.org/0000-0003-2916-7878","observed_orcids":["https://orcid.org/0000-0003-2916-7878"]},"institutions":[{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arny A. Ferrando","raw_affiliation_strings":["Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060298854","display_name":"Robert R. Wolfe","orcid":"https://orcid.org/0000-0003-3425-8889","observed_orcids":["https://orcid.org/0000-0003-3425-8889"]},"institutions":[{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert R. Wolfe","raw_affiliation_strings":["Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014429489","display_name":"David Newcomb Herndon","orcid":"https://orcid.org/0000-0002-3861-6463","observed_orcids":["https://orcid.org/0000-0002-3861-6463","https://orcid.org/0000-0003-0396-9442"]},"institutions":[{"id":"https://openalex.org/I2801713311","display_name":"Shriners Hospitals for Children - Galveston","ror":"https://ror.org/01v95tx09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801713311","https://openalex.org/I4210144267"]},{"id":"https://openalex.org/I4210144267","display_name":"Shriners Hospitals for Children","ror":"https://ror.org/03e8tm275","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210144267"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David N. Herndon","raw_affiliation_strings":["Dr. David N. Herndon, Shriners Hospitals for Children, 815 Market St., Galveston, TX 77550","Shriners Hospitals for Children#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. David N. Herndon, Shriners Hospitals for Children, 815 Market St., Galveston, TX 77550","institution_ids":["https://openalex.org/I2801713311","https://openalex.org/I4210144267"]},{"raw_affiliation_string":"Shriners Hospitals for Children#TAB#","institution_ids":["https://openalex.org/I4210144267"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5014429489","https://openalex.org/A5041106533","https://openalex.org/A5055903272","https://openalex.org/A5060298854","https://openalex.org/A5087352178","https://openalex.org/A5088819443","https://openalex.org/A5112393202"],"corresponding_institution_ids":["https://openalex.org/I2801713311","https://openalex.org/I4210144267","https://openalex.org/I55302922"],"apc_list":null,"apc_paid":null,"fwci":13.6101,"has_fulltext":false,"cited_by_count":282,"citation_normalized_percentile":{"value":0.9925307,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"233","issue":"4","first_page":"556","last_page":"564"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.7455999851226807,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.7455999851226807,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition","score":0.16019999980926514,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.03880000114440918,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxandrolone","display_name":"oxandrolone","score":1.0},{"id":"https://openalex.org/keywords/severe-burns","display_name":"severe burns","score":0.6809999942779541},{"id":"https://openalex.org/keywords/pediatric-burns","display_name":"pediatric burns","score":0.7879999876022339},{"id":"https://openalex.org/keywords/muscle-protein-degradation","display_name":"muscle protein degradation","score":0.9520000219345093},{"id":"https://openalex.org/keywords/muscle-protein-synthesis","display_name":"muscle protein synthesis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/anabolic-androgenic-steroids","display_name":"anabolic steroids","score":0.7300000190734863},{"id":"https://openalex.org/keywords/cachexia","display_name":"cachexia","score":0.7770000100135803},{"id":"https://openalex.org/keywords/malnutrition","display_name":"malnutrition","score":0.746999979019165},{"id":"https://openalex.org/keywords/critically-ill-children","display_name":"critically ill children","score":0.7720000147819519},{"id":"https://openalex.org/keywords/anabolic-therapy","display_name":"anabolic therapy","score":0.39100000262260437}],"concepts":[{"id":"https://openalex.org/C2779733885","wikidata":"https://www.wikidata.org/wiki/Q420859","display_name":"Oxandrolone","level":4,"score":0.9969438910484314},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8985366821289062},{"id":"https://openalex.org/C197683979","wikidata":"https://www.wikidata.org/wiki/Q14876077","display_name":"Protein catabolism","level":3,"score":0.5406280755996704},{"id":"https://openalex.org/C2776782833","wikidata":"https://www.wikidata.org/wiki/Q3454235","display_name":"Total body surface area","level":2,"score":0.497684508562088},{"id":"https://openalex.org/C1008401","wikidata":"https://www.wikidata.org/wiki/Q184681","display_name":"Anabolism","level":2,"score":0.47496268153190613},{"id":"https://openalex.org/C2779390809","wikidata":"https://www.wikidata.org/wiki/Q309438","display_name":"Anabolic steroid","level":3,"score":0.4694364070892334},{"id":"https://openalex.org/C2777464067","wikidata":"https://www.wikidata.org/wiki/Q5958306","display_name":"Hypermetabolism","level":2,"score":0.4598065912723541},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44822627305984497},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35994070768356323},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34385451674461365},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.16771435737609863},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010074","descriptor_name":"Oxandrolone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016038","descriptor_name":"Skin Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045930","descriptor_name":"Anabolic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/00000658-200104000-00012","doi":"https://doi.org/10.1097/00000658-200104000-00012","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000658-200104000-00012","pdf_url":null,"source":{"id":"https://openalex.org/S157664895","display_name":"Annals of Surgery","issn_l":"0003-4932","issn":["0003-4932","1528-1140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgery","raw_type":"journal-article"},{"id":"pmid:11303139","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11303139","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of surgery","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1421286","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1421286/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Surg","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1421286","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1421286/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Surg","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2466779072","display_name":"Modulation of the post-burn catabolic response by modification of androgen and glucocorticoid pathways","funder_award_id":"P50GM060338","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4798589793","display_name":null,"funder_award_id":"5RO1GM5729503","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G771588341","display_name":null,"funder_award_id":"1P 50GM60338-01","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8749653816","display_name":null,"funder_award_id":"2T32GM5729503","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W44893099","https://openalex.org/W58859461","https://openalex.org/W65437593","https://openalex.org/W578069077","https://openalex.org/W1965677004","https://openalex.org/W1967763552","https://openalex.org/W1967775253","https://openalex.org/W1971512681","https://openalex.org/W1971532741","https://openalex.org/W1973588762","https://openalex.org/W1973634422","https://openalex.org/W1980332131","https://openalex.org/W1985645871","https://openalex.org/W1985693526","https://openalex.org/W1986473287","https://openalex.org/W1990173190","https://openalex.org/W1994211035","https://openalex.org/W2002688952","https://openalex.org/W2012568362","https://openalex.org/W2015789611","https://openalex.org/W2016416148","https://openalex.org/W2025109953","https://openalex.org/W2031909175","https://openalex.org/W2033287940","https://openalex.org/W2033571177","https://openalex.org/W2036097231","https://openalex.org/W2056815770","https://openalex.org/W2069199585","https://openalex.org/W2087595669","https://openalex.org/W2108594627","https://openalex.org/W2115173605","https://openalex.org/W2122493788","https://openalex.org/W2124562662","https://openalex.org/W2127475498","https://openalex.org/W2149903422","https://openalex.org/W2156239755","https://openalex.org/W2183437665","https://openalex.org/W2325918023","https://openalex.org/W2406485623","https://openalex.org/W2410639562","https://openalex.org/W2414082932","https://openalex.org/W2417274258"],"related_works":["https://openalex.org/W1970478509","https://openalex.org/W2921018150","https://openalex.org/W2085657776","https://openalex.org/W2064393638","https://openalex.org/W2167750655","https://openalex.org/W2114986671","https://openalex.org/W4389026900","https://openalex.org/W2003608077","https://openalex.org/W4280578445","https://openalex.org/W2048243702"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"explore":[2],"the":[3,72,78,191,197,229],"hypothesis":[4],"that":[5,39],"oxandrolone":[6,129,167,192,198,216,232],"may":[7],"reverse":[8],"muscle":[9,25,157,218,235],"catabolism":[10,237],"in":[11,43,60,71,93,171,186,190,196,233,238],"cachectic,":[12,239],"critically":[13,94,240],"ill":[14,95],"pediatric":[15],"burn":[16,22,79,214],"patients.":[17,48],"SUMMARY":[18],"BACKGROUND":[19],"DATA:":[20],"Severe":[21],"causes":[23],"exaggerated":[24],"protein":[26,143,182,204,208,219,223,236],"catabolism,":[27],"contributing":[28],"to":[29,77,118],"weakness":[30],"and":[31,46,89,106,109,123,150,154,166,174,188],"delayed":[32],"healing.":[33],"Oxandrolone":[34],"is":[35],"an":[36],"anabolic":[37],"steroid":[38],"has":[40],"been":[41],"used":[42],"cachectic":[44],"hepatitis":[45],"AIDS":[47],"METHODS:":[49],"Fourteen":[50],"severely":[51],"burned":[52],"children":[53,96],"were":[54,115,145,169],"enrolled":[55],"during":[56,159],"a":[57,61,68,160],"5-month":[58],"period":[59],"prospective":[62],"cohort":[63],"analytic":[64],"study.":[65],"There":[66],"was":[67,200,210],"prolonged":[69],"delay":[70],"arrival":[73],"of":[74,86,128,176,231],"these":[75],"patients":[76,103],"unit":[80],"for":[81],"definitive":[82],"care.":[83,113],"This":[84],"neglect":[85],"skin":[87,107],"grafting":[88,108],"nutritional":[90],"support":[91],"resulted":[92],"with":[97,202],"significant":[98],"malnutrition.":[99],"On":[100],"arrival,":[101],"all":[102],"underwent":[104],"excision":[105],"received":[110],"similar":[111,170],"clinical":[112],"Subjects":[114],"studied":[116],"5":[117],"7":[119],"days":[120],"after":[121,125],"admission,":[122],"again":[124],"1":[126],"week":[127],"treatment":[130],"at":[131],"0.1":[132],"mg/kg":[133],"by":[134],"mouth":[135],"twice":[136],"daily":[137],"or":[138],"no":[139],"pharmacologic":[140],"treatment.":[141],"Muscle":[142,181,207],"kinetics":[144],"derived":[146],"from":[147],"femoral":[148],"arterial":[149],"venous":[151],"blood":[152],"samples":[153],"vastus":[155],"lateralis":[156],"biopsies":[158],"stable":[161],"isotope":[162],"infusion.":[163],"RESULTS:":[164],"Control":[165],"subjects":[168],"age,":[172],"weight,":[173],"percentage":[175],"body":[177],"surface":[178],"area":[179],"burned.":[180],"net":[183],"balance":[184],"decreased":[185],"controls":[187],"improved":[189],"group.":[193],"The":[194],"improvement":[195],"group":[199],"associated":[201],"increased":[203],"synthesis":[205,224],"efficiency.":[206,225],"breakdown":[209],"unchanged.":[211],"CONCLUSIONS:":[212],"In":[213],"victims,":[215],"improves":[217],"metabolism":[220],"through":[221],"enhanced":[222],"These":[226],"findings":[227],"suggest":[228],"efficacy":[230],"impeding":[234],"injured":[241],"children.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}