{"id":"https://openalex.org/W1997369235","doi":"https://doi.org/10.1111/j.1365-2257.1991.tb00268.x","title":"Storage and preparation of samples for erythropoietin radioimmunoassay","display_name":"Storage and preparation of samples for erythropoietin radioimmunoassay","publication_year":2008,"publication_date":"2008-06-28","ids":{"openalex":"https://openalex.org/W1997369235","doi":"https://doi.org/10.1111/j.1365-2257.1991.tb00268.x","mag":"1997369235","pmid":"https://pubmed.ncbi.nlm.nih.gov/1934928"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2257.1991.tb00268.x","doi":"https://doi.org/10.1111/j.1365-2257.1991.tb00268.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2257.1991.tb00268.x","pdf_url":null,"source":{"id":"https://openalex.org/S60626753","display_name":"Clinical & Laboratory Haematology","issn_l":"0141-9854","issn":["0141-9854","1365-2257"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Laboratory Haematology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025224481","display_name":"R. G. Kendall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R.G. KENDALL","raw_affiliation_strings":["Department of Haematology, Leeds General Infirmary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Leeds General Infirmary","institution_ids":["https://openalex.org/I1295121038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111583096","display_name":"Catherine Eluned Chapman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. CHAPMAN","raw_affiliation_strings":["Department of Chemical Pathology, Leeds General Infirmary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Pathology, Leeds General Infirmary","institution_ids":["https://openalex.org/I1295121038"]}]},{"author_position":"middle","author":{"id":null,"display_name":"A.E. HARTLEY","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A.E. HARTLEY","raw_affiliation_strings":["Department of Haematology, Leeds General Infirmary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Leeds General Infirmary","institution_ids":["https://openalex.org/I1295121038"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111521547","display_name":"D. R. Norfolk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D.R. NORFOLK","raw_affiliation_strings":["Department of Haematology, Leeds General Infirmary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Leeds General Infirmary","institution_ids":["https://openalex.org/I1295121038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1295121038"],"apc_list":null,"apc_paid":null,"fwci":0.4264,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.66675145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"13","issue":"2","first_page":"189","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.02280000038444996,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.013199999928474426,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":1.0},{"id":"https://openalex.org/keywords/radioimmunoassay","display_name":"radioimmunoassay","score":0.9800000190734863},{"id":"https://openalex.org/keywords/sample-storage","display_name":"sample storage","score":0.8960000276565552},{"id":"https://openalex.org/keywords/serum-stability","display_name":"serum stability","score":0.6629999876022339},{"id":"https://openalex.org/keywords/radioactive-tracers","display_name":"radioactive tracers","score":0.8970000147819519},{"id":"https://openalex.org/keywords/heparin","display_name":"heparin","score":0.6000000238418579},{"id":"https://openalex.org/keywords/edta-plasma","display_name":"EDTA plasma","score":0.9079999923706055},{"id":"https://openalex.org/keywords/sample-preparation","display_name":"sample preparation","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.9357757568359375},{"id":"https://openalex.org/C2778534260","wikidata":"https://www.wikidata.org/wiki/Q218706","display_name":"Erythropoietin","level":2,"score":0.8914144039154053},{"id":"https://openalex.org/C74414138","wikidata":"https://www.wikidata.org/wiki/Q886549","display_name":"Venipuncture","level":2,"score":0.7841581702232361},{"id":"https://openalex.org/C2779909307","wikidata":"https://www.wikidata.org/wiki/Q1660181","display_name":"Immunogen","level":4,"score":0.671473503112793},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.49762585759162903},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.48871350288391113},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.4502970576286316},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.386789470911026},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37581655383110046},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2946270704269409},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2265785038471222},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20989134907722473},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.1282893717288971},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.08323651552200317}],"mesh":[{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001793","descriptor_name":"Blood Preservation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015925","descriptor_name":"Cryopreservation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-2257.1991.tb00268.x","doi":"https://doi.org/10.1111/j.1365-2257.1991.tb00268.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2257.1991.tb00268.x","pdf_url":null,"source":{"id":"https://openalex.org/S60626753","display_name":"Clinical & Laboratory Haematology","issn_l":"0141-9854","issn":["0141-9854","1365-2257"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Laboratory Haematology","raw_type":"journal-article"},{"id":"pmid:1934928","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1934928","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and laboratory haematology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W22312786","https://openalex.org/W72802891","https://openalex.org/W155033731","https://openalex.org/W1541049769","https://openalex.org/W1966621021","https://openalex.org/W1972226511","https://openalex.org/W2010978252","https://openalex.org/W2019289959","https://openalex.org/W2022604215","https://openalex.org/W2029738096","https://openalex.org/W2036952926","https://openalex.org/W2057728941","https://openalex.org/W2067581356","https://openalex.org/W2160383525","https://openalex.org/W2315613377","https://openalex.org/W2419186123","https://openalex.org/W7073623773"],"related_works":["https://openalex.org/W2057728941","https://openalex.org/W2066914106","https://openalex.org/W2360254808","https://openalex.org/W75103655","https://openalex.org/W2415748921","https://openalex.org/W2413952635","https://openalex.org/W2067581356","https://openalex.org/W2028876673","https://openalex.org/W1968136099","https://openalex.org/W4398778132"],"abstract_inverted_index":{"The":[0,51],"evaluation":[1],"of":[2,19],"a":[3],"radioimmunoassay":[4],"for":[5,38,48,54],"erythropoietin":[6,31],"developed":[7],"using":[8],"recombinant":[9],"material":[10],"as":[11],"immunogen":[12],"and":[13,23,43,62],"radiotracer":[14],"is":[15],"presented.":[16],"A":[17],"series":[18],"serum":[20],"samples":[21,58],"prepared":[22],"stored":[24],"under":[25],"varying":[26],"conditions":[27],"showed":[28],"that":[29],"immunoreactive":[30],"levels":[32],"were":[33,70],"stable":[34],"at":[35,39,44],"room":[36],"temperature":[37],"least":[40],"10":[41],"days":[42],"-20":[45],"degrees":[46],"C":[47],"5":[49],"months.":[50],"optimum":[52],"time":[53],"separating":[55],"sera":[56],"from":[57],"was":[59],"between":[60],"6":[61],"24":[63],"h":[64],"after":[65],"venepuncture.":[66],"Serum":[67],"EPO":[68],"values":[69],"significantly":[71],"higher":[72],"than":[73],"those":[74],"measured":[75],"in":[76],"heparin":[77],"or":[78],"potassium":[79],"EDTA":[80],"plasma.":[81]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}