{"id":"https://openalex.org/W1997358250","doi":"https://doi.org/10.1007/s10856-012-4638-y","title":"The application of layered double hydroxide clay (LDH)-poly(lactide-co-glycolic acid) (PLGA) film composites for the controlled release of antibiotics","display_name":"The application of layered double hydroxide clay (LDH)-poly(lactide-co-glycolic acid) (PLGA) film composites for the controlled release of antibiotics","publication_year":2012,"publication_date":"2012-04-19","ids":{"openalex":"https://openalex.org/W1997358250","doi":"https://doi.org/10.1007/s10856-012-4638-y","mag":"1997358250","pmid":"https://pubmed.ncbi.nlm.nih.gov/22528072"},"language":"en","primary_location":{"id":"doi:10.1007/s10856-012-4638-y","doi":"https://doi.org/10.1007/s10856-012-4638-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10856-012-4638-y","pdf_url":null,"source":{"id":"https://openalex.org/S166781098","display_name":"Journal of Materials Science Materials in Medicine","issn_l":"0957-4530","issn":["0957-4530","1573-4838"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Science: Materials in Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032425653","display_name":"Michelle Chakraborti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Michelle Chakraborti","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada","institution_ids":["https://openalex.org/I141945490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069458499","display_name":"John K. Jackson","orcid":"https://orcid.org/0000-0002-1401-3035","observed_orcids":["https://orcid.org/0000-0002-1401-3035"]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"John K. Jackson","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada","institution_ids":["https://openalex.org/I141945490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058368188","display_name":"David Plackett","orcid":"https://orcid.org/0000-0002-9958-9315","observed_orcids":["https://orcid.org/0000-0002-9958-9315"]},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"David Plackett","raw_affiliation_strings":["Danish Polymer Center, Department of Chemical Engineering, Technical University of Denmark, Building 229, S\u00f8ltofts Plads, 2800 Kgs., Lyngby, Denmark","Danish Polymer Center Department of Chemical Engineering, Technical University of Denmark, Lyngby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Danish Polymer Center, Department of Chemical Engineering, Technical University of Denmark, Building 229, S\u00f8ltofts Plads, 2800 Kgs., Lyngby, Denmark","institution_ids":["https://openalex.org/I96673099"]},{"raw_affiliation_string":"Danish Polymer Center Department of Chemical Engineering, Technical University of Denmark, Lyngby, Denmark","institution_ids":["https://openalex.org/I96673099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113219507","display_name":"Samuel E. Gilchrist","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Samuel E. Gilchrist","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada","institution_ids":["https://openalex.org/I141945490"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011116882","display_name":"Helen M. Burt","orcid":"https://orcid.org/0000-0003-3039-0532","observed_orcids":["https://orcid.org/0000-0003-3039-0532"]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Helen M. Burt","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Faculty of Pharmaceutical#R#                    Sciences, University of British Columbia, Vancouver, Canada","institution_ids":["https://openalex.org/I141945490"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5069458499"],"corresponding_institution_ids":["https://openalex.org/I141945490"],"apc_list":{"value":2590,"currency":"USD","value_usd":2590},"apc_paid":null,"fwci":1.8254,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.84701419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"23","issue":"7","first_page":"1705","last_page":"1713"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11940","display_name":"Layered Double Hydroxides Synthesis and Applications","score":0.9477999806404114,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11940","display_name":"Layered Double Hydroxides Synthesis and Applications","score":0.9477999806404114,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11852","display_name":"Clay minerals and soil interactions","score":0.04809999838471413,"subfield":{"id":"https://openalex.org/subfields/1906","display_name":"Geochemistry and Petrology"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/layered-double-hydroxides","display_name":"layered double hydroxides","score":0.8690000176429749},{"id":"https://openalex.org/keywords/poly-lactic-co-glycolic-acid","display_name":"poly(lactic-co-glycolic acid)","score":0.8379999995231628},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.7739999890327454},{"id":"https://openalex.org/keywords/antibiotics","display_name":"antibiotics","score":0.6959999799728394},{"id":"https://openalex.org/keywords/polymer-films","display_name":"polymer films","score":0.6990000009536743},{"id":"https://openalex.org/keywords/vancomycin","display_name":"vancomycin","score":0.7210000157356262},{"id":"https://openalex.org/keywords/sodium-fusidate","display_name":"sodium fusidate","score":0.9440000057220459},{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":0.8489999771118164},{"id":"https://openalex.org/keywords/tetracycline","display_name":"tetracycline","score":0.9150000214576721},{"id":"https://openalex.org/keywords/5-fluorouracil","display_name":"5-fluorouracil","score":0.9940000176429749},{"id":"https://openalex.org/keywords/staphylococcus-epidermidis","display_name":"Staphylococcus epidermidis","score":0.9279999732971191},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.7879999876022339},{"id":"https://openalex.org/keywords/implant-coatings","display_name":"implant coatings","score":0.6690000295639038},{"id":"https://openalex.org/keywords/bone-cement","display_name":"bone cement","score":0.5049999952316284},{"id":"https://openalex.org/keywords/burst-release","display_name":"burst release","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.9250656366348267},{"id":"https://openalex.org/C2780472526","wikidata":"https://www.wikidata.org/wiki/Q409373","display_name":"Glycolic acid","level":4,"score":0.8607670068740845},{"id":"https://openalex.org/C2775896084","wikidata":"https://www.wikidata.org/wiki/Q425597","display_name":"Hydroxide","level":2,"score":0.7794713973999023},{"id":"https://openalex.org/C2780165375","wikidata":"https://www.wikidata.org/wiki/Q2102907","display_name":"PLGA","level":3,"score":0.7558290958404541},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.6183315515518188},{"id":"https://openalex.org/C2778002958","wikidata":"https://www.wikidata.org/wiki/Q17078098","display_name":"Layered double hydroxides","level":3,"score":0.5046659708023071},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.316122829914093},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.19936099648475647},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.1199488639831543},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.08051711320877075},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077182","descriptor_name":"Polylactic Acid-Polyglycolic Acid Copolymer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077215","descriptor_name":"Clay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000538","descriptor_name":"Aluminum Silicates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011100","descriptor_name":"Polyglycolic Acid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10856-012-4638-y","doi":"https://doi.org/10.1007/s10856-012-4638-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10856-012-4638-y","pdf_url":null,"source":{"id":"https://openalex.org/S166781098","display_name":"Journal of Materials Science Materials in Medicine","issn_l":"0957-4530","issn":["0957-4530","1573-4838"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Science: Materials in Medicine","raw_type":"journal-article"},{"id":"pmid:22528072","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22528072","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of materials science. Materials in medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/25e4f6a5-483b-4579-8435-7038036d31fe","doi":null,"is_oa":false,"landing_page_url":"https://orbit.dtu.dk/en/publications/25e4f6a5-483b-4579-8435-7038036d31fe","pdf_url":null,"source":{"id":"https://openalex.org/S4306400705","display_name":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I96673099","host_organization_name":"Technical University of Denmark","host_organization_lineage":["https://openalex.org/I96673099"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chakraborti , M , Jackson , J K , Plackett , D , Gilchrist , S E & Burt , H M 2012 , ' The application of layered double hydroxide clay (LDH)-poly(lactide-co-glycolic acid) (PLGA) film composites for the controlled release of antibiotics ' , Journal of Materials Science: Materials in Medicine , vol. 23 , no. 7 , pp. 1705-1713 . https://doi.org/10.1007/s10856-012-4638-y","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W587085147","https://openalex.org/W1968949240","https://openalex.org/W1983975459","https://openalex.org/W1988235799","https://openalex.org/W1993850123","https://openalex.org/W2004036804","https://openalex.org/W2010951835","https://openalex.org/W2012342395","https://openalex.org/W2013744733","https://openalex.org/W2015721897","https://openalex.org/W2018169465","https://openalex.org/W2027379106","https://openalex.org/W2051431655","https://openalex.org/W2057545038","https://openalex.org/W2063284724","https://openalex.org/W2073707850","https://openalex.org/W2088199766","https://openalex.org/W2089531456","https://openalex.org/W2092308338","https://openalex.org/W2095191638","https://openalex.org/W2120593627","https://openalex.org/W2121609624","https://openalex.org/W2128957216","https://openalex.org/W2133712597","https://openalex.org/W2139072846"],"related_works":["https://openalex.org/W3005195291","https://openalex.org/W2729261070","https://openalex.org/W2037348890","https://openalex.org/W2095191638","https://openalex.org/W2086489442","https://openalex.org/W2139072846","https://openalex.org/W2941612261","https://openalex.org/W2947369999","https://openalex.org/W2026794721","https://openalex.org/W2921976432"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}