{"id":"https://openalex.org/W1997357414","doi":"https://doi.org/10.1134/s0026893307040206","title":"Analysis of NAT2 point mutations with biological microchips","display_name":"Analysis of NAT2 point mutations with biological microchips","publication_year":2007,"publication_date":"2007-08-01","ids":{"openalex":"https://openalex.org/W1997357414","doi":"https://doi.org/10.1134/s0026893307040206","mag":"1997357414"},"language":"en","primary_location":{"id":"doi:10.1134/s0026893307040206","doi":"https://doi.org/10.1134/s0026893307040206","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s0026893307040206","pdf_url":null,"source":{"id":"https://openalex.org/S191406736","display_name":"Molecular Biology","issn_l":"0026-8933","issn":["0026-8933","0026-8984","1608-3245","3034-5553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015206648","display_name":"\u0416. \u041c. \u041a\u043e\u0436\u0435\u043a\u0431\u0430\u0435\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100098275","display_name":"Engelhardt Institute of Molecular Biology","ror":"https://ror.org/027hwkg23","country_code":"RU","type":"facility","lineage":["https://openalex.org/I100098275","https://openalex.org/I1313323035","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210148309","display_name":"Vavilov Institute of General Genetics","ror":"https://ror.org/05ermrg42","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210148309"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Zh. M. Kozhekbaeva","raw_affiliation_strings":["Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia","Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia","Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]},{"raw_affiliation_string":"Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210148309"]},{"raw_affiliation_string":"Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]},{"raw_affiliation_string":"Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210148309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086194186","display_name":"Andrey Sergeyevich Glotov","orcid":"https://orcid.org/0000-0002-7465-4504","observed_orcids":["https://orcid.org/0000-0002-7465-4504"]},"institutions":[{"id":"https://openalex.org/I4210089964","display_name":"Research Institute of Obstetrics and Gynecology named after D.O. Ott","ror":"https://ror.org/009qtkb56","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210089964","https://openalex.org/I4210110862"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. S. Glotov","raw_affiliation_strings":["Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg, 199034, Russia","Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences. St. Petersburg, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg, 199034, Russia","institution_ids":["https://openalex.org/I4210089964"]},{"raw_affiliation_string":"Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences. St. Petersburg, Russia","institution_ids":["https://openalex.org/I4210089964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052806984","display_name":"\u041e. \u0410. \u0413\u0440\u0430","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100098275","display_name":"Engelhardt Institute of Molecular Biology","ror":"https://ror.org/027hwkg23","country_code":"RU","type":"facility","lineage":["https://openalex.org/I100098275","https://openalex.org/I1313323035","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"O. A. Gra","raw_affiliation_strings":["Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]},{"raw_affiliation_string":"\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075181672","display_name":"Irina V. Goldenkova-Pavlova","orcid":"https://orcid.org/0000-0003-2270-065X","observed_orcids":["https://orcid.org/0000-0003-2270-065X"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210148309","display_name":"Vavilov Institute of General Genetics","ror":"https://ror.org/05ermrg42","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210148309"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"I. V. Goldenkova-Pavlova","raw_affiliation_strings":["Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia","Vavilov Institute of general genetics, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210148309"]},{"raw_affiliation_string":"Vavilov Institute of general genetics, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210148309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048608040","display_name":"Sergey Alexandrovich Bruskin","orcid":"https://orcid.org/0000-0003-0653-7418","observed_orcids":["https://orcid.org/0000-0003-0653-7418"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210148309","display_name":"Vavilov Institute of General Genetics","ror":"https://ror.org/05ermrg42","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210148309"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"S. A. Bruskin","raw_affiliation_strings":["Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia","Vavilov Institute of general genetics, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210148309"]},{"raw_affiliation_string":"Vavilov Institute of general genetics, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210148309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045215769","display_name":"\u0415. \u0415. \u0410\u0433\u0430\u0444\u043e\u043d\u043e\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210122842","display_name":"Center for Theoretical Problems of Physicochemical Pharmacology","ror":"https://ror.org/02ncvqp37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210115279","https://openalex.org/I4210122842"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"E. E. Agafonova","raw_affiliation_strings":["Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]},{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053341304","display_name":"\u041c\u0430\u0440\u043a\u0430\u0440\u043e\u0432\u0430 \u0415\u043a\u0430\u0442\u0435\u0440\u0438\u043d\u0430 \u0412\u0430\u0441\u0438\u043b\u044c\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0002-2028-566X","observed_orcids":["https://orcid.org/0000-0002-2028-566X"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210122842","display_name":"Center for Theoretical Problems of Physicochemical Pharmacology","ror":"https://ror.org/02ncvqp37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210115279","https://openalex.org/I4210122842"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"E. V. Markarova","raw_affiliation_strings":["Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]},{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007732418","display_name":"R. M. Abdeev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210122842","display_name":"Center for Theoretical Problems of Physicochemical Pharmacology","ror":"https://ror.org/02ncvqp37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210115279","https://openalex.org/I4210122842"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"R. M. Abdeev","raw_affiliation_strings":["Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]},{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033406721","display_name":"Irina  Markovna Korsunskaya","orcid":"https://orcid.org/0000-0002-6583-0318","observed_orcids":["https://orcid.org/0000-0002-6583-0318"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210122842","display_name":"Center for Theoretical Problems of Physicochemical Pharmacology","ror":"https://ror.org/02ncvqp37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210115279","https://openalex.org/I4210122842"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"I. M. Korsunskaya","raw_affiliation_strings":["Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]},{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007396216","display_name":"\u041f\u0438\u0440\u0443\u0437\u044f\u043d \u0410\u043d\u0430\u0441\u0442\u0430\u0441 \u041b\u044c\u0432\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0001-8039-8474","observed_orcids":["https://orcid.org/0000-0001-8039-8474"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210122842","display_name":"Center for Theoretical Problems of Physicochemical Pharmacology","ror":"https://ror.org/02ncvqp37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210115279","https://openalex.org/I4210122842"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. L. Piruzyan","raw_affiliation_strings":["Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]},{"raw_affiliation_string":"Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210122842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110466136","display_name":"Viktor E. Barsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100098275","display_name":"Engelhardt Institute of Molecular Biology","ror":"https://ror.org/027hwkg23","country_code":"RU","type":"facility","lineage":["https://openalex.org/I100098275","https://openalex.org/I1313323035","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"V. E. Barsky","raw_affiliation_strings":["Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]},{"raw_affiliation_string":"\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019010641","display_name":"Alexander S. Zasedatelev","orcid":"https://orcid.org/0000-0003-0760-0562","observed_orcids":["https://orcid.org/0000-0003-0760-0562"]},"institutions":[{"id":"https://openalex.org/I100098275","display_name":"Engelhardt Institute of Molecular Biology","ror":"https://ror.org/027hwkg23","country_code":"RU","type":"facility","lineage":["https://openalex.org/I100098275","https://openalex.org/I1313323035","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. S. Zasedatelev","raw_affiliation_strings":["Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]},{"raw_affiliation_string":"\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102708013","display_name":"Tatiana V. Nasedkina","orcid":"https://orcid.org/0000-0002-2642-4202","observed_orcids":["https://orcid.org/0000-0002-2642-4202"]},"institutions":[{"id":"https://openalex.org/I100098275","display_name":"Engelhardt Institute of Molecular Biology","ror":"https://ror.org/027hwkg23","country_code":"RU","type":"facility","lineage":["https://openalex.org/I100098275","https://openalex.org/I1313323035","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"T. V. Nasedkina","raw_affiliation_strings":["Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]},{"raw_affiliation_string":"\u2002Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia","institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5015206648","https://openalex.org/A5102708013"],"corresponding_institution_ids":["https://openalex.org/I100098275","https://openalex.org/I1313323035","https://openalex.org/I4210148309"],"apc_list":null,"apc_paid":null,"fwci":0.8092,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.67047308,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"4","first_page":"656","last_page":"664"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-acetyltransferase-2","display_name":"N-acetyltransferase 2","score":0.9259999990463257},{"id":"https://openalex.org/keywords/nat2","display_name":"NAT2","score":0.7239999771118164},{"id":"https://openalex.org/keywords/point-mutations","display_name":"point mutations","score":0.9649999737739563},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.6779999732971191},{"id":"https://openalex.org/keywords/acetylator-phenotype","display_name":"acetylator phenotype","score":0.8709999918937683},{"id":"https://openalex.org/keywords/dna-genotyping","display_name":"DNA genotyping","score":0.5329999923706055},{"id":"https://openalex.org/keywords/aromatic-amines","display_name":"aromatic amines","score":0.7900000214576721},{"id":"https://openalex.org/keywords/2-aminofluorene","display_name":"2-aminofluorene","score":0.8479999899864197},{"id":"https://openalex.org/keywords/4-aminobiphenyl","display_name":"4-aminobiphenyl","score":0.9120000004768372},{"id":"https://openalex.org/keywords/restriction-enzyme-analysis","display_name":"restriction enzyme analysis","score":0.625},{"id":"https://openalex.org/keywords/predictive-medicine","display_name":"predictive medicine","score":0.5960000157356262},{"id":"https://openalex.org/keywords/personalized-treatment","display_name":"personalized treatment","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C176944494","wikidata":"https://www.wikidata.org/wiki/Q1415380","display_name":"Point mutation","level":4,"score":0.5456642508506775},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5186635255813599},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38580256700515747},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.2928944230079651},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2919650375843048},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11506739258766174}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1134/s0026893307040206","doi":"https://doi.org/10.1134/s0026893307040206","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s0026893307040206","pdf_url":null,"source":{"id":"https://openalex.org/S191406736","display_name":"Molecular Biology","issn_l":"0026-8933","issn":["0026-8933","0026-8984","1608-3245","3034-5553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334801","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1826275591","https://openalex.org/W1988855705","https://openalex.org/W1990540391","https://openalex.org/W1994262939","https://openalex.org/W1996770386","https://openalex.org/W1998815097","https://openalex.org/W2014352349","https://openalex.org/W2023226934","https://openalex.org/W2051174436","https://openalex.org/W2053053126","https://openalex.org/W2062272756","https://openalex.org/W2066081857","https://openalex.org/W2071316377","https://openalex.org/W2074457276","https://openalex.org/W2092128596","https://openalex.org/W2115592448","https://openalex.org/W2135420670","https://openalex.org/W2155331961","https://openalex.org/W2182950825","https://openalex.org/W2415794599","https://openalex.org/W2416276389"],"related_works":["https://openalex.org/W2425583526","https://openalex.org/W2795250660","https://openalex.org/W2263267632","https://openalex.org/W2011750871","https://openalex.org/W7216851902","https://openalex.org/W2400308603","https://openalex.org/W2145270651","https://openalex.org/W2146496142","https://openalex.org/W2074457276","https://openalex.org/W1492223707"],"abstract_inverted_index":{"The":[0,54,88,119],"NAT2":[1,52,120,178],"product,":[2],"N-acetyltransferase":[3],"2,":[4],"is":[5,113],"involved":[6],"in":[7,188],"biotransformation":[8],"and":[9,19,25,27,48,77,82,106,168,191],"detoxification":[10],"of":[11,51,97,128,150,176],"several":[12],"aromatic":[13],"amines":[14],"(in":[15],"particular,":[16],"2-aminofluorene,":[17],"4-aminobiphenyl,":[18],"4-naphthylamine),":[20],"which":[21,44],"are":[22],"strongly":[23],"mutagenic":[24],"carcinogenic,":[26],"acetylates":[28],"some":[29],"drugs,":[30],"affecting":[31],"their":[32],"metabolism.":[33],"A":[34],"biological":[35],"microchip":[36],"was":[37,122],"developed":[38],"to":[39,63,156,186],"detect":[40],"16":[41,148],"point":[42],"mutations,":[43],"determine":[45],"36":[46],"alleles":[47,84,93],"660":[49],"genotypes":[50,55,153],".":[53],"can":[56],"be":[57],"divided":[58],"into":[59],"four":[60],"groups":[61,67],"according":[62],"the":[64,92,133,145,151,157,171,181],"acetylator":[65,146,182],"phenotype:":[66],"with":[68],"rapid":[69],"(R/R),":[70],"intermediate":[71,81],"(R/S),":[72],"or":[73,86,110,160],"slow":[74,83],"(S/S)":[75],"acetylation":[76],"a":[78],"group":[79,90,158],"combining":[80,162],"(\u201cR/S":[85],"S/S\u201d).":[87],"last":[89],"includes":[91],"determined":[94],"by":[95,115,139],"combinations":[96],"seven":[98],"mutations":[99,163],"(191G/A,":[100],"282C/T,":[101,164],"341T/C,":[102,165],"481C/T,":[103,166],"590G/A,":[104,167],"803A/G,":[105],"857G/A),":[107],"whose":[108],"cis":[109],"trans":[111],"position":[112],"detectable":[114],"restriction":[116],"enzyme":[117],"analysis.":[118],"genotype":[121,183],"unequivocally":[123],"established":[124],"for":[125],"37":[126],"out":[127,149],"71":[129],"DNA":[130],"specimens,":[131],"while":[132],"other":[134],"34":[135,152],"specimens":[136],"were":[137,154],"characterized":[138],"more":[140],"than":[141],"two":[142],"genotypes.":[143],"By":[144],"phenotype,":[147],"assigned":[155],"\u201cR/S":[159],"S/S,\u201d":[161],"803A/G.":[169],"Thus,":[170],"biochip":[172],"allows":[173],"primary":[174],"analysis":[175],"most":[177],"polymorphic":[179],"substitutions,":[180],"being":[184],"important":[185],"know":[187],"predictive":[189],"medicine":[190],"individualized":[192],"therapy.":[193]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}