{"id":"https://openalex.org/W1997351179","doi":"https://doi.org/10.1136/sti.75.6.420","title":"Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial. DITRAME Study Group","display_name":"Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial. DITRAME Study Group","publication_year":1999,"publication_date":"1999-12-01","ids":{"openalex":"https://openalex.org/W1997351179","doi":"https://doi.org/10.1136/sti.75.6.420","mag":"1997351179","pmid":"https://pubmed.ncbi.nlm.nih.gov/10754950","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1758266"},"language":"en","primary_location":{"id":"doi:10.1136/sti.75.6.420","doi":"https://doi.org/10.1136/sti.75.6.420","is_oa":true,"landing_page_url":"https://doi.org/10.1136/sti.75.6.420","pdf_url":"https://sti.bmj.com/content/sextrans/75/6/420.full.pdf","source":{"id":"https://openalex.org/S112197712","display_name":"Sexually Transmitted Infections","issn_l":"0007-134X","issn":["0007-134X","0266-4348","1368-4973","1472-3263"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sexually Transmitted Infections","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://sti.bmj.com/content/sextrans/75/6/420.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107866077","display_name":"Philippe Msellati","orcid":"https://orcid.org/0000-0003-2568-1626","observed_orcids":["https://orcid.org/0000-0003-2568-1626"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Msellati","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075916576","display_name":"Nicolas M\u00e9da","orcid":"https://orcid.org/0000-0003-2523-8747","observed_orcids":["https://orcid.org/0000-0003-2523-8747"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Meda","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065596403","display_name":"Val\u00e9riane Leroy","orcid":"https://orcid.org/0000-0003-3542-8616","observed_orcids":["https://orcid.org/0000-0003-3542-8616"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. Leroy","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072914009","display_name":"Ruffin Likikou\u00ebt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Likikouet","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049548693","display_name":"Philippe Van de Perre","orcid":"https://orcid.org/0000-0002-3912-0427","observed_orcids":["https://orcid.org/0000-0002-3912-0427"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Van de Perre","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053181312","display_name":"Michel Cartoux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Cartoux","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050572554","display_name":"Dominique Bonard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Bonard","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042632706","display_name":"Amadou Ouangr\u00e9","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Ouangre","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. Combe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Combe","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011922701","display_name":"Lucile Gautier-Charpentier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Gautier-Charpentier","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030776758","display_name":"Fatoumata Sylla\u2010Koko","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Sylla-Koko","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043272630","display_name":"R. Lassalle","orcid":"https://orcid.org/0000-0001-6726-6215","observed_orcids":["https://orcid.org/0000-0001-6726-6215"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Lassalle","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044346534","display_name":"Mireille Bretin Dosso","orcid":"https://orcid.org/0000-0003-4744-8235","observed_orcids":["https://orcid.org/0000-0003-4744-8235"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Dosso","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008222792","display_name":"Christiane Welffens-Ekra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Welffens-Ekra","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049440373","display_name":"Fran\u00e7ois Dabis","orcid":"https://orcid.org/0000-0002-1614-8857","observed_orcids":["https://orcid.org/0000-0002-1614-8857"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Dabis","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036742391","display_name":"Laurent Mandelbrot","orcid":"https://orcid.org/0000-0002-5883-7597","observed_orcids":["https://orcid.org/0000-0002-5883-7597"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Mandelbrot","raw_affiliation_strings":["Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme SIDA ORSTOM, Abidjan, C\u00f4te d'Ivoire","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6827,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":{"value":0.93102354,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"75","issue":"6","first_page":"420","last_page":"425"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13206","display_name":"Neonatal skin health care","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzalkonium-chloride","display_name":"benzalkonium chloride","score":0.9589999914169312},{"id":"https://openalex.org/keywords/perinatal-hiv-transmission","display_name":"perinatal HIV transmission","score":0.8399999737739563},{"id":"https://openalex.org/keywords/hiv-in-pregnancy","display_name":"HIV in pregnancy","score":0.8119999766349792},{"id":"https://openalex.org/keywords/perinatal-hiv-prevention","display_name":"perinatal HIV prevention","score":0.7149999737739563},{"id":"https://openalex.org/keywords/treatment-acceptability","display_name":"treatment acceptability","score":0.5630000233650208},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.7250000238418579},{"id":"https://openalex.org/keywords/neonatal-dermatitis","display_name":"neonatal dermatitis","score":0.6480000019073486},{"id":"https://openalex.org/keywords/conjunctivitis","display_name":"conjunctivitis","score":0.8619999885559082},{"id":"https://openalex.org/keywords/compliance","display_name":"compliance","score":0.3880000114440918},{"id":"https://openalex.org/keywords/west-africa","display_name":"West Africa","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9270893931388855},{"id":"https://openalex.org/C2775919038","wikidata":"https://www.wikidata.org/wiki/Q108126784","display_name":"Benzalkonium chloride","level":2,"score":0.8876587152481079},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6475862264633179},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5367556810379028},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.45753294229507446},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.42688941955566406},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.41588544845581055},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.36406081914901733},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3454131484031677},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.19647365808486938},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1923229992389679},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.088714599609375},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000282","descriptor_name":"Administration, Intravaginal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000891","descriptor_name":"Anti-Infective Agents, Local","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001548","descriptor_name":"Benzalkonium Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002050","descriptor_name":"Burkina Faso","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007560","descriptor_name":"Cote d'Ivoire","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010342","descriptor_name":"Patient Acceptance of Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010349","descriptor_name":"Patient Compliance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014623","descriptor_name":"Vaginal Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015498","descriptor_name":"HIV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018445","descriptor_name":"Infectious Disease Transmission, Vertical","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1136/sti.75.6.420","doi":"https://doi.org/10.1136/sti.75.6.420","is_oa":true,"landing_page_url":"https://doi.org/10.1136/sti.75.6.420","pdf_url":"https://sti.bmj.com/content/sextrans/75/6/420.full.pdf","source":{"id":"https://openalex.org/S112197712","display_name":"Sexually Transmitted Infections","issn_l":"0007-134X","issn":["0007-134X","0266-4348","1368-4973","1472-3263"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sexually Transmitted Infections","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1758266","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1758266","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sex Transm Infect","raw_type":"Text"},{"id":"pmid:10754950","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10754950","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sexually transmitted infections","raw_type":"Clinical Trial"},{"id":"mag:2187172362","doi":null,"is_oa":false,"landing_page_url":"https://sti.bmj.com/content/75/6/420.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1136/sti.75.6.420","doi":"https://doi.org/10.1136/sti.75.6.420","is_oa":true,"landing_page_url":"https://doi.org/10.1136/sti.75.6.420","pdf_url":"https://sti.bmj.com/content/sextrans/75/6/420.full.pdf","source":{"id":"https://openalex.org/S112197712","display_name":"Sexually Transmitted Infections","issn_l":"0007-134X","issn":["0007-134X","0266-4348","1368-4973","1472-3263"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sexually Transmitted Infections","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1997351179.pdf","grobid_xml":"https://content.openalex.org/works/W1997351179.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1488502950","https://openalex.org/W1969901476","https://openalex.org/W1989303064","https://openalex.org/W2007982200","https://openalex.org/W2015182853","https://openalex.org/W2016227202","https://openalex.org/W2024423837","https://openalex.org/W2034859822","https://openalex.org/W2051464900","https://openalex.org/W2063236554","https://openalex.org/W2086265375","https://openalex.org/W2090864305","https://openalex.org/W2101858999","https://openalex.org/W2102051568","https://openalex.org/W2102919880","https://openalex.org/W2118010208","https://openalex.org/W2248487830","https://openalex.org/W2253352374","https://openalex.org/W2325419959","https://openalex.org/W2412271200","https://openalex.org/W2414487054","https://openalex.org/W2418358469","https://openalex.org/W2527016823"],"related_works":["https://openalex.org/W2330385092","https://openalex.org/W2187172362","https://openalex.org/W2211768816","https://openalex.org/W2141976594","https://openalex.org/W7097673305","https://openalex.org/W2415826549","https://openalex.org/W2029049568","https://openalex.org/W2132126238","https://openalex.org/W6997172915","https://openalex.org/W2128030125"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"study":[2],"the":[3,143,156,201,207,212,218,231,241],"tolerance":[4],"and":[5,38,46,53,101,133,140,153,158,193,198,235,244,250,264],"acceptability":[6],"in":[7,34,67,136,155,163,268,273],"Africa":[8],"of":[9,57,63,89,99,142,150,179,220,233],"a":[10,86,102,131,262],"perinatal":[11],"intervention":[12,267],"to":[13,74,172,279],"prevent":[14],"vertical":[15,275],"HIV":[16,276],"transmission":[17,277],"using":[18],"benzalkonium":[19,91,112,242,259],"chloride":[20,92,113,243,260],"disinfection.":[21],"DESIGN:":[22],"A":[23,61],"randomized,":[24],"double":[25],"blinded":[26],"phase":[27],"II":[28],"trial.":[29],"SETTING:":[30],"Prenatal":[31],"care":[32],"units":[33],"Abidjan":[35],"(C\u00f4te":[36],"d'Ivoire)":[37],"Bobo-Dioulasso":[39],"(Burkina":[40],"Faso).":[41],"PATIENTS:":[42],"Women":[43,82],"accepting":[44],"testing":[45],"counselling":[47],"who":[48],"were":[49,59,127,165],"seropositive":[50],"for":[51,191,195,200],"HIV-1":[52],"under":[54],"37":[55],"weeks":[56,98],"pregnancy":[58],"eligible.":[60],"total":[62],"108":[64],"women":[65,137,157],"(54":[66],"each":[68],"group)":[69],"enrolled":[70],"from":[71,96],"November":[72],"1996":[73],"April":[75],"1997,":[76],"with":[77,110,130,258],"their":[78],"informed":[79],"consent.":[80],"INTERVENTION:":[81],"self":[83],"administered":[84],"daily":[85],"vaginal":[87],"suppository":[88],"1%":[90,111],"or":[93,115,160],"matched":[94],"placebo":[95,116,245],"36":[97],"pregnancy,":[100],"single":[103],"intrapartum":[104,196],"dose.":[105],"The":[106,148,176],"neonate":[107,144],"was":[108,182,189,216],"bathed":[109],"solution":[114],"within":[117],"30":[118],"minutes":[119],"after":[120],"birth.":[121],"MAIN":[122],"OUTCOME":[123],"MEASURES:":[124],"Adverse":[125],"events":[126,162,222],"recorded":[128],"weekly,":[129],"questionnaire":[132],"speculum":[134],"examination":[135,141],"through":[138,145],"delivery,":[139],"day":[146],"30.":[147],"incidence":[149,219,232],"genital":[151],"signs":[152],"symptoms":[154],"cutaneous":[159],"ophthalmological":[161],"newborns":[164],"compared":[166],"between":[167,206,226,240],"groups":[168,246],"on":[169],"an":[170],"intent":[171],"treat":[173],"basis.":[174],"RESULTS:":[175],"median":[177],"duration":[178],"prepartum":[180,192],"treatment":[181,227],"21":[183],"days":[184],"(range":[185],"0-87":[186],"days).":[187],"Compliance":[188],"87%":[190],"69%":[194],"treatment,":[197],"88%":[199],"neonatal":[202],"bath,":[203],"without":[204],"differences":[205],"two":[208],"groups.":[209,228],"In":[210,229],"women,":[211],"most":[213],"frequent":[214],"event":[215],"leucorrhoea;":[217],"adverse":[221],"did":[223,237],"not":[224,238],"differ":[225,239],"children,":[230],"dermatitis":[234],"conjunctivitis":[236],"(p":[247],"=":[248,252],"0.16":[249],"p":[251],"0.29,":[253],"respectively).":[254],"CONCLUSION:":[255],"Vaginal":[256],"disinfection":[257],"is":[261],"feasible":[263],"well":[265],"tolerated":[266],"west":[269],"Africa.":[270],"Its":[271],"efficacy":[272],"preventing":[274],"remains":[278],"be":[280],"demonstrated.":[281]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}