{"id":"https://openalex.org/W1997304990","doi":"https://doi.org/10.1074/jbc.270.24.14247","title":"Homophilic Interactions Mediated by Receptor Tyrosine Phosphatases \u03bc and \u03ba. A CRITICAL ROLE FOR THE NOVEL EXTRACELLULAR MAM DOMAIN","display_name":"Homophilic Interactions Mediated by Receptor Tyrosine Phosphatases \u03bc and \u03ba. A CRITICAL ROLE FOR THE NOVEL EXTRACELLULAR MAM DOMAIN","publication_year":1995,"publication_date":"1995-06-01","ids":{"openalex":"https://openalex.org/W1997304990","doi":"https://doi.org/10.1074/jbc.270.24.14247","mag":"1997304990","pmid":"https://pubmed.ncbi.nlm.nih.gov/7782276"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.270.24.14247","doi":"https://doi.org/10.1074/jbc.270.24.14247","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.270.24.14247","pdf_url":"http://www.jbc.org/article/S0021925818920454/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jbc.org/article/S0021925818920454/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091856094","display_name":"Gerben C. M. Zondag","orcid":"https://orcid.org/0009-0006-2087-1024","observed_orcids":["https://orcid.org/0009-0006-2087-1024"]},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Gerben C.M. Zondag","raw_affiliation_strings":["Division of Cellular Biochemistry, The Netherlands Cancer Institute, Amsterdam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Amsterdam","institution_ids":["https://openalex.org/I2898336195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037381969","display_name":"Gregory M. Koningstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Gregory M. Koningstein","raw_affiliation_strings":["Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands","Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121 1066 CX Amsterdam The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898336195"]},{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121 1066 CX Amsterdam The Netherlands","institution_ids":["https://openalex.org/I2898336195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103804270","display_name":"Yingping Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ying-Ping Jiang","raw_affiliation_strings":["Department of Pharmacology, New York University Medical Center, New York, New York 10016"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, New York University Medical Center, New York, New York 10016","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111894825","display_name":"Jan Sap","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jan Sap","raw_affiliation_strings":["Department of Pharmacology, New York University Medical Center, New York, New York 10016"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, New York University Medical Center, New York, New York 10016","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061490638","display_name":"Wouter H. Moolenaar","orcid":"https://orcid.org/0000-0001-7545-198X","observed_orcids":["https://orcid.org/0000-0001-7545-198X"]},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Wouter H. Moolenaar","raw_affiliation_strings":["Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands","Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121 1066 CX Amsterdam The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898336195"]},{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121 1066 CX Amsterdam The Netherlands","institution_ids":["https://openalex.org/I2898336195"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071741692","display_name":"Martijn F.B.G. Gebbink","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Martijn F.B.G. Gebbink","raw_affiliation_strings":["Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands","Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121 1066 CX Amsterdam The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898336195"]},{"raw_affiliation_string":"Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121 1066 CX Amsterdam The Netherlands","institution_ids":["https://openalex.org/I2898336195"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5061490638"],"corresponding_institution_ids":["https://openalex.org/I2898336195"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":5.092,"has_fulltext":true,"cited_by_count":156,"citation_normalized_percentile":{"value":0.96496405,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"270","issue":"24","first_page":"14247","last_page":"14250"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.012500000186264515,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/receptor-protein-tyrosine-phosphatase","display_name":"receptor tyrosine phosphatase","score":0.906000018119812},{"id":"https://openalex.org/keywords/mam-domain","display_name":"MAM domain","score":0.9629999995231628},{"id":"https://openalex.org/keywords/homophilic-adhesion","display_name":"homophilic adhesion","score":0.9290000200271606},{"id":"https://openalex.org/keywords/cell-cell-adhesion","display_name":"cell-cell adhesion","score":0.7850000262260437},{"id":"https://openalex.org/keywords/ectodomain-structure","display_name":"ectodomain structure","score":0.6119999885559082},{"id":"https://openalex.org/keywords/fibronectin-type-iii-repeats","display_name":"fibronectin type III repeats","score":0.9010000228881836},{"id":"https://openalex.org/keywords/ig-like-domains","display_name":"immunoglobulin-like domains","score":0.8090000152587891},{"id":"https://openalex.org/keywords/fusion-protein","display_name":"fusion protein","score":0.6660000085830688},{"id":"https://openalex.org/keywords/receptor-specificity","display_name":"receptor specificity","score":0.36899998784065247}],"concepts":[{"id":"https://openalex.org/C85528070","wikidata":"https://www.wikidata.org/wiki/Q643602","display_name":"Protein tyrosine phosphatase","level":3,"score":0.7391687631607056},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.7182304859161377},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5923384428024292},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.521213173866272},{"id":"https://openalex.org/C178666793","wikidata":"https://www.wikidata.org/wiki/Q422476","display_name":"Phosphatase","level":3,"score":0.46819835901260376},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4591928720474243},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.4531354308128357},{"id":"https://openalex.org/C101544691","wikidata":"https://www.wikidata.org/wiki/Q420511","display_name":"Receptor tyrosine kinase","level":3,"score":0.4339030086994171},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4095069468021393},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32672297954559326},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21834531426429749},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.18511813879013062},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.06020882725715637},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018411","descriptor_name":"Spodoptera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018411","descriptor_name":"Spodoptera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018411","descriptor_name":"Spodoptera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054623","descriptor_name":"Receptor-Like Protein Tyrosine Phosphatases, Class 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054623","descriptor_name":"Receptor-Like Protein Tyrosine Phosphatases, Class 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054623","descriptor_name":"Receptor-Like Protein Tyrosine Phosphatases, Class 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054635","descriptor_name":"Receptor-Like Protein Tyrosine Phosphatases, Class 8","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054635","descriptor_name":"Receptor-Like Protein Tyrosine Phosphatases, Class 8","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054635","descriptor_name":"Receptor-Like Protein Tyrosine Phosphatases, Class 8","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.270.24.14247","doi":"https://doi.org/10.1074/jbc.270.24.14247","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.270.24.14247","pdf_url":"http://www.jbc.org/article/S0021925818920454/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:7782276","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7782276","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.270.24.14247","doi":"https://doi.org/10.1074/jbc.270.24.14247","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.270.24.14247","pdf_url":"http://www.jbc.org/article/S0021925818920454/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322777","display_name":"KWF Kankerbestrijding","ror":"https://ror.org/0368jnd28"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1997304990.pdf","grobid_xml":"https://content.openalex.org/works/W1997304990.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1504159440","https://openalex.org/W1583907090","https://openalex.org/W1674557579","https://openalex.org/W1853885983","https://openalex.org/W1864169613","https://openalex.org/W1976634502","https://openalex.org/W2009310436","https://openalex.org/W2010295320","https://openalex.org/W2012514869","https://openalex.org/W2036220212","https://openalex.org/W2059452371","https://openalex.org/W2069472625","https://openalex.org/W2085634797","https://openalex.org/W2090373637","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2107784203","https://openalex.org/W2126658684","https://openalex.org/W2410744491"],"related_works":["https://openalex.org/W2903581235","https://openalex.org/W4317831504","https://openalex.org/W4225369895","https://openalex.org/W2043949158","https://openalex.org/W4248003880","https://openalex.org/W2016528530","https://openalex.org/W3214925036","https://openalex.org/W2047780246","https://openalex.org/W936482795","https://openalex.org/W2161577603"],"abstract_inverted_index":{"The":[0,32],"receptor-like":[1],"protein":[2],"tyrosine":[3],"phosphatases":[4],"(RPTP)":[5],"mu":[6,60,84,111,122,146,159,166,179],"and":[7,25,44,61,85,180,189],"RPTP":[8,59,62,83,86,110,121,145,153,158,165,168,178,181],"kappa":[9,63,87,182],"have":[10],"a":[11,21,26,92,108,143],"modular":[12],"ectodomain":[13],"consisting":[14],"of":[15,34,99,152,177,194],"four":[16],"fibronectin":[17],"type":[18],"III-like":[19],"repeats,":[20],"single":[22],"Ig-like":[23],"domain,":[24],"newly":[27],"identified":[28],"N-terminal":[29],"MAM":[30,101,114,150,175],"domain.":[31],"function":[33],"the":[35,97,100,113,127,149,174,192],"latter":[36],"module,":[37],"which":[38],"comprises":[39],"about":[40],"160":[41],"amino":[42],"acids":[43],"is":[45,51,123,139,183],"found":[46],"in":[47,71,91,103,116,142],"diverse":[48],"transmembrane":[49],"proteins,":[50],"not":[52,161],"known.":[53],"We":[54],"previously":[55],"reported":[56],"that":[57,77,173],"both":[58],"can":[64],"mediate":[65],"homophilic":[66,104,186],"cell":[67,128,137],"interactions":[68],"when":[69],"expressed":[70,107,125],"insect":[72,117],"cells.":[73,119],"Here":[74],"we":[75,106],"show":[76],"despite":[78],"their":[79],"striking":[80],"structural":[81],"similarity,":[82],"fail":[88],"to":[89,132],"interact":[90,162],"heterophilic":[93],"manner.":[94],"To":[95],"examine":[96],"role":[98],"domain":[102,115,151,176],"binding,":[105],"mutant":[109],"lacking":[112],"Sf9":[118],"Truncated":[120],"properly":[124],"at":[126],"surface":[129],"but":[130],"fails":[131],"promote":[133],"cell-cell":[134,187],"adhesion.":[135],"Homophilic":[136],"adhesion":[138],"fully":[140],"restored":[141],"chimeric":[144,157],"molecule":[147],"containing":[148],"kappa.":[154,169],"However,":[155],"this":[156],"does":[160],"with":[163],"either":[164],"or":[167],"These":[170],"results":[171],"indicate":[172],"essential":[184],"for":[185],"interaction":[188],"helps":[190],"determine":[191],"specificity":[193],"these":[195],"interactions.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}