{"id":"https://openalex.org/W1997266531","doi":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","title":"A Prospective Cohort Study of the Prevalence of Growth, Facial, and Central Nervous System Abnormalities in Children with Heavy Prenatal Alcohol Exposure","display_name":"A Prospective Cohort Study of the Prevalence of Growth, Facial, and Central Nervous System Abnormalities in Children with Heavy Prenatal Alcohol Exposure","publication_year":2012,"publication_date":"2012-07-23","ids":{"openalex":"https://openalex.org/W1997266531","doi":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","mag":"1997266531","pmid":"https://pubmed.ncbi.nlm.nih.gov/22823161","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4162305"},"language":"en","primary_location":{"id":"doi:10.1111/j.1530-0277.2012.01794.x","doi":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1530-0277.2012.01794.x","source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical and Experimental Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1530-0277.2012.01794.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112868439","display_name":"Devon Kuehn","orcid":"https://orcid.org/0000-0001-7422-3600","observed_orcids":["https://orcid.org/0000-0001-7422-3600"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Devon Kuehn","raw_affiliation_strings":["Bethesda, Maryland Department of Pediatrics, National Capital Consortium, Bethesda, Maryland","Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bethesda, Maryland Department of Pediatrics, National Capital Consortium, Bethesda, Maryland","institution_ids":[]},{"raw_affiliation_string":"Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108429259","display_name":"Sof\u00eda Aros A","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Sof\u00eda Aros","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023213381","display_name":"FERNANDO G. CASSORLA","orcid":"https://orcid.org/0000-0003-0958-5845","observed_orcids":["https://orcid.org/0000-0003-0958-5845"]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Fernando Cassorla","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","Institute of Maternal and Child Research (IDIMI) Faculty of Medicine University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]},{"raw_affiliation_string":"Institute of Maternal and Child Research (IDIMI) Faculty of Medicine University of Chile Santiago Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022184308","display_name":"Mar\u00eda Francisca Lopez Avaria","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Maria Avaria","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032543815","display_name":"Nancy Unanue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Nancy Unanue","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109001520","display_name":"Cecilia Henriquez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Cecilia Henriquez","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027963728","display_name":"Karin Kleinsteuber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Karin Kleinsteuber","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056246232","display_name":"B\u00e1rbara Conca","orcid":"https://orcid.org/0000-0001-9607-3412","observed_orcids":["https://orcid.org/0000-0001-9607-3412"]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Barbara Conca","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110033648","display_name":"Alejandra \u00c1vila","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156682","display_name":"Hospital San Borja Arriar\u00e1n","ror":"https://ror.org/04qdwp261","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210156682"]},{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Alejandra Avila","raw_affiliation_strings":["Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics San Borja Arriar\u00e1n Clinical Hospital Santiago, Chile University of Chile Santiago Chile","institution_ids":["https://openalex.org/I4210156682","https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023143537","display_name":"Tonia C. Carter","orcid":"https://orcid.org/0000-0002-2107-7838","observed_orcids":["https://orcid.org/0000-0002-2107-7838"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tonia C. Carter","raw_affiliation_strings":["Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110106818","display_name":"Mary R. Conley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary R. Conley","raw_affiliation_strings":["Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026424955","display_name":"James F. Troendle","orcid":"https://orcid.org/0000-0002-7903-1015","observed_orcids":["https://orcid.org/0000-0002-7903-1015"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Troendle","raw_affiliation_strings":["Division of Cardiovascular Sciences , National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Sciences , National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103077118","display_name":"James L. Mills","orcid":"https://orcid.org/0000-0003-4496-332X","observed_orcids":["https://orcid.org/0000-0003-4496-332X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James L. Mills","raw_affiliation_strings":["Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5103077118"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":null,"fwci":6.1709,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.96575446,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"36","issue":"10","first_page":"1811","last_page":"1819"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-alcohol-exposure","display_name":"prenatal alcohol exposure","score":0.746999979019165},{"id":"https://openalex.org/keywords/fetal-alcohol-spectrum-disorders","display_name":"fetal alcohol spectrum disorders","score":0.9750000238418579},{"id":"https://openalex.org/keywords/fetal-alcohol-syndrome","display_name":"fetal alcohol syndrome","score":0.9750000238418579},{"id":"https://openalex.org/keywords/central-nervous-system-abnormalities","display_name":"central nervous system malformations","score":0.8529999852180481},{"id":"https://openalex.org/keywords/growth-restriction","display_name":"growth restriction","score":0.9229999780654907},{"id":"https://openalex.org/keywords/facial-anomalies","display_name":"facial anomalies","score":0.796999990940094},{"id":"https://openalex.org/keywords/binge-drinking","display_name":"binge drinking","score":0.8790000081062317},{"id":"https://openalex.org/keywords/child-development-outcomes","display_name":"child development outcomes","score":0.5070000290870667},{"id":"https://openalex.org/keywords/chile","display_name":"Chile","score":0.3779999911785126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7920851707458496},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7440975904464722},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.7365373969078064},{"id":"https://openalex.org/C2776679223","wikidata":"https://www.wikidata.org/wiki/Q1521260","display_name":"Binge drinking","level":4,"score":0.7104908227920532},{"id":"https://openalex.org/C2777601104","wikidata":"https://www.wikidata.org/wiki/Q400277","display_name":"Fetal alcohol syndrome","level":3,"score":0.6198751926422119},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5213231444358826},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.5199241042137146},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5102648735046387},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4901781678199768},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4826265275478363},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.42495211958885193},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.41905373334884644},{"id":"https://openalex.org/C3020575016","wikidata":"https://www.wikidata.org/wiki/Q400277","display_name":"Fetal alcohol","level":3,"score":0.4156954884529114},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22072279453277588},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.1554027795791626},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1334742307662964},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.10378193855285645},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06802910566329956},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000015","descriptor_name":"Abnormalities, Multiple","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000015","descriptor_name":"Abnormalities, Multiple","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000015","descriptor_name":"Abnormalities, Multiple","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001724","descriptor_name":"Birth Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001724","descriptor_name":"Birth Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":true},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009421","descriptor_name":"Nervous System Malformations","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D009421","descriptor_name":"Nervous System Malformations","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009421","descriptor_name":"Nervous System Malformations","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019066","descriptor_name":"Facies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019465","descriptor_name":"Craniofacial Abnormalities","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063647","descriptor_name":"Fetal Alcohol Spectrum Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D063647","descriptor_name":"Fetal Alcohol Spectrum Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1530-0277.2012.01794.x","doi":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1530-0277.2012.01794.x","source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical and Experimental Research","raw_type":"journal-article"},{"id":"pmid:22823161","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22823161","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism, clinical and experimental research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4162305","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4162305","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Alcohol Clin Exp Res","raw_type":"Text"},{"id":"pmh:oai:repositorio.uchile.cl:2250/160027","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.uchile.cl/handle/2250/160027","pdf_url":null,"source":{"id":"https://openalex.org/S4306481413","display_name":"Universidad de Chile","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Alcoholism: Clinical and Experimental Research","raw_type":"Art\u00edculo de revista"}],"best_oa_location":{"id":"doi:10.1111/j.1530-0277.2012.01794.x","doi":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1530-0277.2012.01794.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1530-0277.2012.01794.x","source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical and Experimental Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1470219041","display_name":"Chile Fetal Alcohol Study","funder_award_id":"ZIAHD008802","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337364","display_name":"National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1997266531.pdf","grobid_xml":"https://content.openalex.org/works/W1997266531.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W117149832","https://openalex.org/W1967169915","https://openalex.org/W1977156046","https://openalex.org/W1983997957","https://openalex.org/W1985850646","https://openalex.org/W1986298824","https://openalex.org/W2000741181","https://openalex.org/W2009307603","https://openalex.org/W2017907101","https://openalex.org/W2020260519","https://openalex.org/W2032984569","https://openalex.org/W2066019771","https://openalex.org/W2088299109","https://openalex.org/W2124400149","https://openalex.org/W2127328156","https://openalex.org/W2132895437","https://openalex.org/W2134133901","https://openalex.org/W2135512886","https://openalex.org/W2152948116","https://openalex.org/W2162578295","https://openalex.org/W2164040515","https://openalex.org/W2263779592","https://openalex.org/W2297168669","https://openalex.org/W3137367271","https://openalex.org/W6678938194"],"related_works":["https://openalex.org/W2016689886","https://openalex.org/W160565534","https://openalex.org/W2063991002","https://openalex.org/W4285212716","https://openalex.org/W1948913370","https://openalex.org/W2937388521","https://openalex.org/W2017748263","https://openalex.org/W2980144212","https://openalex.org/W7125391397","https://openalex.org/W1500271554"],"abstract_inverted_index":{"BACKGROUND:":[0],"Most":[1],"children":[2,119,160,168,179,277],"who":[3,59],"are":[4,36],"exposed":[5,118,139,159,178],"to":[6,91,99,121,162,183,198,210,227,242,254,269,319,322],"large":[7],"quantities":[8],"of":[9,26,29,45,94,116,124,137,143,157,165,200,218,235,244,276,288,296],"alcohol":[10,17,31,73,79,271,285,289,324],"in":[11,54,113,134,154],"utero":[12],"do":[13],"not":[14],"develop":[15],"fetal":[16,30],"syndrome":[18],"(FAS).":[19],"Population-based":[20],"prospective":[21,42],"data":[22,81,181],"on":[23],"the":[24,85,117,125,138,144,158,166,176,293,316],"risk":[25,295],"developing":[27],"components":[28],"spectrum":[32],"disorders":[33],"(FASD),":[34],"however,":[35],"limited.":[37],"METHODS:":[38],"This":[39],"was":[40,132],"a":[41],"cohort":[43],"study":[44],"9,628":[46],"women":[47,69],"screened":[48],"during":[49,75,84,273],"their":[50],"first":[51],"prenatal":[52,323],"appointment":[53],"Chile,":[55],"which":[56],"identified":[57],"101":[58,68],"consumed":[60,237],"at":[61,185],"least":[62,186],"4":[63],"drinks/d":[64],"(exposed)":[65],"matched":[66],"with":[67,70,180,262,284],"no":[71,192],"reported":[72],"consumption":[74,80,272],"pregnancy":[76,201,219,245],"(unexposed).":[77],"Detailed":[78],"were":[82,88,111,152,259,299],"collected":[83],"pregnancy.":[86],"Children":[87],"evaluated":[89],"up":[90],"8.5":[92],"years":[93],"age":[95],"by":[96,172],"clinicians":[97],"masked":[98],"exposure":[100,268],"status.":[101],"RESULTS:":[102],"One":[103],"or":[104,280],"more":[105,281],"functional":[106],"central":[107],"nervous":[108],"system":[109],"abnormalities":[110,282],"present":[112,133,153],"44.0%":[114],"(22/50)":[115],"compared":[120,161],"13.6%":[122],"(6/44)":[123],"unexposed":[126,145,167],"(p":[127,146,169],"=":[128,147,170,203,213,230,247,257],"0.002).":[129],"Growth":[130],"restriction":[131],"27.2%":[135],"(25/92)":[136],"and":[140,215,232,302,313],"12.5%":[141],"(12/96)":[142],"0.02).":[148],"Abnormal":[149],"facial":[150],"features":[151],"17.3%":[155],"(14/81)":[156],"1.1%":[163],"(1/89)":[164],"0.0002)":[171],"direct":[173],"examination.":[174],"Of":[175],"59":[177],"available":[182],"detect":[184],"1":[187,279],"abnormality,":[188],"12":[189],"(20.3%)":[190],"had":[191,278],"abnormalities.":[193],"Binge":[194],"drinking":[195,301],"from":[196,240],"conception":[197,241],"recognition":[199,217,243],"(OR":[202,246],"1.48":[204],"per":[205,222,238,249],"day,":[206,223],"95%":[207,224,251],"CI:":[208,225,252],"1.15":[209],"1.91,":[211],"p":[212,229,256],"0.002)":[214],"after":[216],"(OR=":[220],"1.41":[221],"1.01":[226,253],"1.95,":[228],"0.04)":[231],"total":[233,304],"number":[234],"drinks":[236],"week":[239],"1.02":[248],"drink,":[250],"1.04,":[255],"0.0009)":[258],"significantly":[260],"associated":[261,283],"abnormal":[263],"child":[264],"outcome.":[265],"CONCLUSIONS:":[266],"After":[267],"heavy":[270],"pregnancy,":[274],"80%":[275],"exposure.":[286,325],"Patterns":[287],"use":[290],"that":[291],"posed":[292],"greatest":[294],"adverse":[297],"outcomes":[298],"binge":[300],"high":[303],"weekly":[305],"intake.":[306],"Functional":[307],"neurologic":[308],"impairment":[309],"occurred":[310],"most":[311],"frequently":[312],"may":[314],"be":[315],"only":[317],"sign":[318],"alert":[320],"physicians":[321]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
