{"id":"https://openalex.org/W1997246501","doi":"https://doi.org/10.1055/s-2007-983141","title":"Der Effekt von Salbutamol auf die elektrische Impedanz der Lunge extrem Fr\u00fchgeborener","display_name":"Der Effekt von Salbutamol auf die elektrische Impedanz der Lunge extrem Fr\u00fchgeborener","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1997246501","doi":"https://doi.org/10.1055/s-2007-983141","mag":"1997246501"},"language":"de","primary_location":{"id":"doi:10.1055/s-2007-983141","doi":"https://doi.org/10.1055/s-2007-983141","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-983141","pdf_url":null,"source":{"id":"https://openalex.org/S72845316","display_name":"Zeitschrift f\u00fcr Geburtshilfe und Neonatologie","issn_l":"0948-2393","issn":["0948-2393","1439-1651"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Geburtshilfe und Neonatologie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074742011","display_name":"M Kuscha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M Kuscha","raw_affiliation_strings":["Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen","institution_ids":["https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110185977","display_name":"E. Raithel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"E Raithel","raw_affiliation_strings":["Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen","institution_ids":["https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064594669","display_name":"Mathias Klemme","orcid":"https://orcid.org/0000-0001-7825-8288","observed_orcids":["https://orcid.org/0000-0001-7825-8288"]},"institutions":[{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M Klemme","raw_affiliation_strings":["Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen","institution_ids":["https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114127795","display_name":"A. Schulze","orcid":"https://orcid.org/0000-0001-7551-8566","observed_orcids":["https://orcid.org/0000-0001-7551-8566"]},"institutions":[{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A Schulze","raw_affiliation_strings":["Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen","institution_ids":["https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008142938","display_name":"Ulrich Herbert Thome","orcid":"https://orcid.org/0000-0003-3570-9418","observed_orcids":["https://orcid.org/0000-0003-3570-9418"]},"institutions":[{"id":"https://openalex.org/I4210155144","display_name":"University Hospital Ulm","ror":"https://ror.org/05emabm63","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210155144"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"U Thome","raw_affiliation_strings":["Universit\u00e4ts\u2013Kinderklinik, Ulm"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e4ts\u2013Kinderklinik, Ulm","institution_ids":["https://openalex.org/I4210155144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103642369","display_name":"AW Flemmer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"AW Flemmer","raw_affiliation_strings":["Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neonatologie der Kinderklinik am Perinatalzentrum Gro\u00dfhadern, LMU-M\u00fcnchen, M\u00fcnchen","institution_ids":["https://openalex.org/I8204097"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"211","issue":"S 1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11778","display_name":"Electrical and Bioimpedance Tomography","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salbutamol","display_name":"salbutamol","score":0.9950000047683716},{"id":"https://openalex.org/keywords/extremely-preterm-infants","display_name":"extremely preterm infants","score":0.8849999904632568},{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.9359999895095825},{"id":"https://openalex.org/keywords/enac","display_name":"epithelial sodium channel","score":0.656000018119812},{"id":"https://openalex.org/keywords/beta-2-adrenergic-agonists","display_name":"beta2-adrenergic agonists","score":0.7689999938011169},{"id":"https://openalex.org/keywords/impedance-tomography","display_name":"impedance tomography","score":0.746999979019165},{"id":"https://openalex.org/keywords/neonatal-respiratory-support","display_name":"neonatal respiratory support","score":0.48399999737739563},{"id":"https://openalex.org/keywords/lung-maturation","display_name":"lung maturation","score":0.3970000147819519},{"id":"https://openalex.org/keywords/neonatal-intensive-care","display_name":"neonatal intensive care","score":0.3319999873638153}],"concepts":[{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.7215452790260315},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3411436080932617}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-2007-983141","doi":"https://doi.org/10.1055/s-2007-983141","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-983141","pdf_url":null,"source":{"id":"https://openalex.org/S72845316","display_name":"Zeitschrift f\u00fcr Geburtshilfe und Neonatologie","issn_l":"0948-2393","issn":["0948-2393","1439-1651"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Geburtshilfe und Neonatologie","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1693164639","https://openalex.org/W1737149724","https://openalex.org/W1970551607","https://openalex.org/W2162939070","https://openalex.org/W1883862493","https://openalex.org/W4246407663","https://openalex.org/W2081895749","https://openalex.org/W2122054208","https://openalex.org/W2059958418","https://openalex.org/W2089361818"],"abstract_inverted_index":{"Hintergrund:":[0],"Der":[1,239],"spezifische":[2,135,226],"elektrische":[3,307],"Widerstand":[4,136,227],"(Rs)":[5,139],"des":[6,97,150,204,314],"Lungengewebes":[7],"h\u00e4ngt":[8],"neben":[9],"der":[10,15,22,51,56,95,134,137,159,168,221,224,241,257],"Bel\u00fcftung":[11],"auch":[12,302],"vom":[13,122],"Fl\u00fcssigkeitsgehalt":[14],"Lunge":[16,138],"ab.":[17],"Dieser":[18],"ist":[19],"abh\u00e4ngig":[20],"von":[21,76,87,186,245,251,297],"Resorption":[23],"\u00fcber":[24,161],"b-Mimetika-stimulierbare":[25],"epitheliale":[26],"Na-Kan\u00e4le":[27],"(eNaC).":[28],"Bei":[29,194,273],"reifen":[30],"Neugeborenen":[31],"und":[32,44,91,141,164,269,282,323],"Erwachsenen":[33],"kann":[34,324],"Rs":[35,90,252,262,279],"mittels":[36],"Impedanztomographie":[37,308],"(EIT)":[38],"mit":[39,81,116,198],"16":[40,216,298],"Elektroden":[41,132,200],"gemessen":[42,140],"werden":[43,310],"man":[45],"erh\u00e4lt":[46],"so":[47],"ein":[48,183,201],"r\u00e4umliches":[49],"Verteilungsmuster":[50],"Widerst\u00e4nde":[52],"in":[53,210,228],"einem":[54],"Querschnitt":[55],"Lunge.":[57],"Vergleichbare":[58],"Messungen":[59,155],"bei":[60,78,188,263,266,271,303,318],"Fr\u00fchgeborenen":[61],"unter":[62],"1000g":[63],"Geburtsgewicht":[64],"wurden":[65,114,156],"bisher":[66],"nicht":[67,326],"durchgef\u00fchrt.":[68,172],"Fragestellung:":[69],"Im":[70],"Rahmen":[71],"einer":[72,102,215,295],"Pilotstudie":[73],"zu":[74,101,157,191,248],"Einsatz":[75],"Salbutamol":[77,88,117],"extremen":[79,304],"FG":[80,305],"RDS":[82],"untersuchten":[83],"wir":[84,291],"den":[85,143,195,264,274],"Effekt":[86],"auf":[89,178,299],"dessen":[92],"\u00c4nderung":[93,149,250],"w\u00e4hren":[94],"Applikation":[96],"Medikaments":[98],"im":[99,329],"Vergleich":[100,330],"Kontrollgruppe.":[103],"Methodik:":[104],"10":[105],"extrem":[106],"unreife":[107],"Fr\u00fchgeborene":[108],"(540\u2013810g":[109],"GG;":[110],"25+4\u201327":[111],"+4":[112],"SSW)":[113],"randomisiert":[115],"(S)":[118],"oder":[119,253],"Placebo":[120],"(C)":[121,234],"4.":[123],"bis":[124],"11.":[125],"Lebenstag":[126],"behandelt.":[127],"\u00dcber":[128],"8":[129,199,300],"zirkul\u00e4r":[130],"angebrachte":[131],"wurde":[133,175],"aus":[142],"generierten":[144],"Tomogrammen":[145],"die":[146],"mittlere":[147,225],"relative":[148],"Widerstandes":[151],"DRs":[152,270,283],"errechnet.":[153],"Die":[154,312],"Beginn":[158,220,240],"Infusion":[160,169,258],"4":[162,246],"Stunden":[163,247],"erneut":[165],"am":[166,277],"Ende":[167,256],"(Tag":[170],"11)":[171],"Zur":[173],"Messung":[174],"das":[176],"Tidalvolumen":[177],"6\u20137ml/kg":[179],"KG":[180],"adjustiert,":[181],"um":[182,316],"pCO":[184],"2":[185],"45\u201365":[187],"ausgeglichenem":[189],"pH":[190],"erreichen.":[192],"Ergebnisse:":[193],"Patienten":[196],"konnte":[197],"tomographisches":[202],"Bild":[203],"Thorax":[205],"generiert":[206],"werden,":[207],"welches":[208],"erwartungsgem\u00e4\u00df":[209],"seiner":[211],"r\u00e4umlichen":[212],"Aufl\u00f6sung":[213],"deutlich":[214],"Elektroden-Ableitung":[217],"nachsteht.":[218],"Vor":[219],"Salbutamol-Infusion":[222],"war":[223,276,320],"beiden":[229],"Gruppen":[230],"gleich":[231],"(5,4\u00b11,0":[232],"Ohm*m":[233,237,268,281],"vs.":[235],"5,6\u00b10,9":[236],"(S)).":[238],"Medikamentengabe":[242],"f\u00fchrte":[243],"innerhalb":[244],"keiner":[249],"DRs.":[254],"Am":[255],"(11.":[259],"Lebenstag)":[260],"lag":[261],"Kontrollkindern":[265,319],"5,1\u00b10,6":[267],"-6,0\u00b16,9%.":[272],"Sultanolkindern":[275],"Infusionsende":[278],"5,5\u00b11,1":[280],"-1,7\u00b13,7%,":[284],"(N.S.).":[285],"Schlussfolgerung:":[286],"In":[287],"dieser":[288],"Untersuchung":[289],"konnten":[290],"zeigen,":[292],"dass":[293],"mithilfe":[294],"Reduktion":[296],"Messelektroden":[301],"eine":[306],"durchgef\u00fchrt":[309],"kann.":[311],"Abnahme":[313],"Widerstands":[315],"7%":[317],"sehr":[321],"variabel":[322],"deshalb":[325],"als":[327],"Fl\u00fcssigkeitsretention":[328],"zur":[331],"Salbutamolgruppe":[332],"gewertet":[333],"werden.":[334]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}