{"id":"https://openalex.org/W1997202220","doi":"https://doi.org/10.1016/j.vetimm.2008.02.013","title":"An allogeneic hybrid-cell fusion vaccine against canine mammary cancer","display_name":"An allogeneic hybrid-cell fusion vaccine against canine mammary cancer","publication_year":2008,"publication_date":"2008-04-14","ids":{"openalex":"https://openalex.org/W1997202220","doi":"https://doi.org/10.1016/j.vetimm.2008.02.013","mag":"1997202220","pmid":"https://pubmed.ncbi.nlm.nih.gov/18423623"},"language":"en","primary_location":{"id":"doi:10.1016/j.vetimm.2008.02.013","doi":"https://doi.org/10.1016/j.vetimm.2008.02.013","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vetimm.2008.02.013","pdf_url":null,"source":{"id":"https://openalex.org/S194416120","display_name":"Veterinary Immunology and Immunopathology","issn_l":"0165-2427","issn":["0165-2427","1873-2534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Veterinary Immunology and Immunopathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071817275","display_name":"R. Curtis Bird","orcid":"https://orcid.org/0000-0003-0134-7009","observed_orcids":["https://orcid.org/0000-0003-0134-7009"]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"R. Curtis Bird","raw_affiliation_strings":["Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, USA. birdric@vetmed.auburn.edu","Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, USA. birdric@vetmed.auburn.edu","institution_ids":["https://openalex.org/I82497590"]},{"raw_affiliation_string":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050907907","display_name":"Patricia DeInnocentes","orcid":"https://orcid.org/0000-0003-3471-6675","observed_orcids":["https://orcid.org/0000-0003-3471-6675"]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia DeInnocentes","raw_affiliation_strings":["Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108508144","display_name":"Steven Lenz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Lenz","raw_affiliation_strings":["Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024261192","display_name":"Erin E. Thacker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erin E. Thacker","raw_affiliation_strings":["Division of Human Gene Therapy, Department of Medicine, and the Gene Therapy Center, The University of Alabama at Birmingham, Birmingham, AL 35294, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Human Gene Therapy, Department of Medicine, and the Gene Therapy Center, The University of Alabama at Birmingham, Birmingham, AL 35294, United States","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022987623","display_name":"David T. Curiel","orcid":"https://orcid.org/0000-0003-3802-6014","observed_orcids":["https://orcid.org/0000-0003-3802-6014"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David T. Curiel","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Pathology and Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, United States","Division of Human Gene Therapy, Department of Medicine, and the Gene Therapy Center, The University of Alabama at Birmingham, Birmingham, AL 35294, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Pathology and Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, United States","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Division of Human Gene Therapy, Department of Medicine, and the Gene Therapy Center, The University of Alabama at Birmingham, Birmingham, AL 35294, United States","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049397225","display_name":"Bruce Frederic Smith","orcid":"https://orcid.org/0000-0001-8523-0355","observed_orcids":["https://orcid.org/0000-0001-8523-0355"]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce F. Smith","raw_affiliation_strings":["Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States","Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5519, United States","institution_ids":["https://openalex.org/I82497590"]},{"raw_affiliation_string":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, United States","institution_ids":["https://openalex.org/I82497590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5071817275"],"corresponding_institution_ids":["https://openalex.org/I82497590"],"apc_list":{"value":3250,"currency":"USD","value_usd":3250},"apc_paid":null,"fwci":1.2526,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.7789654,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"123","issue":"3-4","first_page":"289","last_page":"304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.8227999806404114,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.8227999806404114,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.17589999735355377,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/canine-mammary-carcinoma","display_name":"canine mammary carcinoma","score":0.9860000014305115},{"id":"https://openalex.org/keywords/tumor-antigen-presentation","display_name":"tumor antigen presentation","score":0.6169999837875366},{"id":"https://openalex.org/keywords/cell-mediated-immunity","display_name":"cell-mediated immunity","score":0.8759999871253967},{"id":"https://openalex.org/keywords/cytotoxic-t-lymphocytes","display_name":"cytotoxic T lymphocytes","score":0.859000027179718},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9229999780654907},{"id":"https://openalex.org/keywords/beagle","display_name":"beagle dogs","score":0.5809999704360962}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7961366176605225},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6166908144950867},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5957709550857544},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5507718324661255},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5247970819473267},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.509446918964386},{"id":"https://openalex.org/C2778170410","wikidata":"https://www.wikidata.org/wiki/Q506253","display_name":"Dendritic cell","level":3,"score":0.46982526779174805},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4582277238368988},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.4564431309700012},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.44593101739883423},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4284038841724396},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002459","descriptor_name":"Cell Fusion","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015674","descriptor_name":"Mammary Neoplasms, Animal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015674","descriptor_name":"Mammary Neoplasms, Animal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015674","descriptor_name":"Mammary Neoplasms, Animal","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.vetimm.2008.02.013","doi":"https://doi.org/10.1016/j.vetimm.2008.02.013","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vetimm.2008.02.013","pdf_url":null,"source":{"id":"https://openalex.org/S194416120","display_name":"Veterinary Immunology and Immunopathology","issn_l":"0165-2427","issn":["0165-2427","1873-2534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Veterinary Immunology and Immunopathology","raw_type":"journal-article"},{"id":"pmid:18423623","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18423623","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Veterinary immunology and immunopathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6485765736","display_name":"Training in Investigative Dermatology","funder_award_id":"T32AR053458","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332725","display_name":"Alabama Agricultural Experiment Station","ror":"https://ror.org/02v80fc35"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W163304737","https://openalex.org/W336368690","https://openalex.org/W563441573","https://openalex.org/W1521620824","https://openalex.org/W1536265448","https://openalex.org/W1570968423","https://openalex.org/W1587935721","https://openalex.org/W1602460865","https://openalex.org/W1710720339","https://openalex.org/W1878421783","https://openalex.org/W1953171279","https://openalex.org/W1963936630","https://openalex.org/W1964545478","https://openalex.org/W1967802864","https://openalex.org/W1972830476","https://openalex.org/W1976104757","https://openalex.org/W1981407497","https://openalex.org/W2025317656","https://openalex.org/W2027741075","https://openalex.org/W2032702007","https://openalex.org/W2035453083","https://openalex.org/W2037942513","https://openalex.org/W2043626559","https://openalex.org/W2049284155","https://openalex.org/W2050949237","https://openalex.org/W2053791216","https://openalex.org/W2055043387","https://openalex.org/W2058530324","https://openalex.org/W2061215455","https://openalex.org/W2087663912","https://openalex.org/W2090774807","https://openalex.org/W2093901976","https://openalex.org/W2094666071","https://openalex.org/W2098367656","https://openalex.org/W2107140931","https://openalex.org/W2107884772","https://openalex.org/W2112064048","https://openalex.org/W2119340334","https://openalex.org/W2125215650","https://openalex.org/W2139044411","https://openalex.org/W2145284995","https://openalex.org/W2154041075","https://openalex.org/W2156057520","https://openalex.org/W2158332359","https://openalex.org/W2163209831","https://openalex.org/W2171547066","https://openalex.org/W2188615991","https://openalex.org/W2264826854","https://openalex.org/W2314963342","https://openalex.org/W2345501009","https://openalex.org/W2408916685","https://openalex.org/W2888866050","https://openalex.org/W4241604000","https://openalex.org/W4293279301","https://openalex.org/W4301110728","https://openalex.org/W6631131526","https://openalex.org/W6672571047","https://openalex.org/W6681504075","https://openalex.org/W6687195872"],"related_works":["https://openalex.org/W2075772957","https://openalex.org/W2972139668","https://openalex.org/W7168126160","https://openalex.org/W2043681403","https://openalex.org/W2098367656","https://openalex.org/W2441887812","https://openalex.org/W2088544147","https://openalex.org/W2405646873","https://openalex.org/W2095086994","https://openalex.org/W2038116480"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}