{"id":"https://openalex.org/W1997140641","doi":"https://doi.org/10.1016/0020-7292(81)90040-0","title":"Placental protein 5 (PP5) in severe pre\u2010eclampsia and eclampsia","display_name":"Placental protein 5 (PP5) in severe pre\u2010eclampsia and eclampsia","publication_year":1981,"publication_date":"1981-03-01","ids":{"openalex":"https://openalex.org/W1997140641","doi":"https://doi.org/10.1016/0020-7292(81)90040-0","mag":"1997140641","pmid":"https://pubmed.ncbi.nlm.nih.gov/6111499"},"language":"en","primary_location":{"id":"doi:10.1016/0020-7292(81)90040-0","doi":"https://doi.org/10.1016/0020-7292(81)90040-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0020-7292(81)90040-0","pdf_url":null,"source":{"id":"https://openalex.org/S4210216427","display_name":"International Journal of Gynecology & Obstetrics","issn_l":"0020-6695","issn":["0020-6695","0020-7292","1879-3479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Gynecology & Obstetrics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073011683","display_name":"J.N. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"J.N. Lee","raw_affiliation_strings":["Departments of Obstetrics and Gynaecology, and Reproductive Physiology, St. Bartholomew's Hospital Medical College, London, EC1, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynaecology, and Reproductive Physiology, St. Bartholomew's Hospital Medical College, London, EC1, United Kingdom","institution_ids":["https://openalex.org/I1307195382","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112405402","display_name":"H.T. Salem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H.T. Salem","raw_affiliation_strings":["Departments of Obstetrics and Gynaecology, and Reproductive Physiology, St. Bartholomew's Hospital Medical College, London, EC1, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynaecology, and Reproductive Physiology, St. Bartholomew's Hospital Medical College, London, EC1, United Kingdom","institution_ids":["https://openalex.org/I1307195382","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111613029","display_name":"S.\u2010C. Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"S.C. Huang","raw_affiliation_strings":["Departments of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taiwan","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042587296","display_name":"Pei Chuan Ouyang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"P.C. Ouyang","raw_affiliation_strings":["Departments of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taiwan","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056382994","display_name":"Markku T. Sepp\u00e4l\u00e4","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"M. Sepp\u00e4l\u00e4","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Central University Hospital, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Central University Hospital, Helsinki, Finland","institution_ids":["https://openalex.org/I2800394112"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108457503","display_name":"T. Chard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"T. Chard","raw_affiliation_strings":["Departments of Obstetrics and Gynaecology, and Reproductive Physiology, St. Bartholomew's Hospital Medical College, London, EC1, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynaecology, and Reproductive Physiology, St. Bartholomew's Hospital Medical College, London, EC1, United Kingdom","institution_ids":["https://openalex.org/I1307195382","https://openalex.org/I166337079"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5073011683"],"corresponding_institution_ids":["https://openalex.org/I1307195382","https://openalex.org/I166337079"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":3.2752,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.89696807,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"19","issue":"1","first_page":"65","last_page":"67"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/placental-protein-5","display_name":"placental protein 5","score":0.9980000257492065},{"id":"https://openalex.org/keywords/severe-preeclampsia","display_name":"severe preeclampsia","score":0.8759999871253967},{"id":"https://openalex.org/keywords/eclampsia","display_name":"eclampsia","score":1.0},{"id":"https://openalex.org/keywords/circulating-biomarkers","display_name":"circulating biomarkers","score":0.7170000076293945}],"concepts":[{"id":"https://openalex.org/C2781276381","wikidata":"https://www.wikidata.org/wiki/Q552348","display_name":"Eclampsia","level":3,"score":0.9426394701004028},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8760902881622314},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4262273907661438},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.366835355758667},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.35850241780281067},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.055630505084991455},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004461","descriptor_name":"Eclampsia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011257","descriptor_name":"Pregnancy Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0020-7292(81)90040-0","doi":"https://doi.org/10.1016/0020-7292(81)90040-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0020-7292(81)90040-0","pdf_url":null,"source":{"id":"https://openalex.org/S4210216427","display_name":"International Journal of Gynecology & Obstetrics","issn_l":"0020-6695","issn":["0020-6695","0020-7292","1879-3479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Gynecology & Obstetrics","raw_type":"journal-article"},{"id":"pmid:6111499","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6111499","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2000397813","https://openalex.org/W2001408632","https://openalex.org/W2011126954","https://openalex.org/W2012402693","https://openalex.org/W2045092741","https://openalex.org/W2048980249","https://openalex.org/W2087077722","https://openalex.org/W2108075456","https://openalex.org/W3006216097"],"related_works":["https://openalex.org/W2048954194","https://openalex.org/W2403598406","https://openalex.org/W2045092741","https://openalex.org/W2048980249","https://openalex.org/W3198674865","https://openalex.org/W3201132838","https://openalex.org/W2073243174","https://openalex.org/W3092511503","https://openalex.org/W2362898968","https://openalex.org/W2417696412"],"abstract_inverted_index":{"Circulating":[0],"methods":[1],"of":[2],"placental":[3,39],"protein":[4],"5":[5],"(PP5)":[6],"were":[7,19],"studied":[8],"in":[9,22,33],"patients":[10],"with":[11],"severe":[12],"preeclampsia":[13],"and":[14],"eclampsia.":[15],"Elevated":[16],"PP5":[17],"levels":[18],"frequently":[20],"observed":[21],"the":[23,38],"eclampsia":[24],"group.":[25],"This":[26],"elevation":[27],"may":[28],"be":[29],"due":[30],"to":[31],"disturbance":[32],"endogenous":[34],"coagulation":[35],"mechanisms":[36],"at":[37],"site.":[40]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}