{"id":"https://openalex.org/W1997081962","doi":"https://doi.org/10.1007/s10396-008-0195-x","title":"Therapeutic potential of low-intensity ultrasound (part 2): biomolecular effects, sonotransfection, and sonopermeabilization","display_name":"Therapeutic potential of low-intensity ultrasound (part 2): biomolecular effects, sonotransfection, and sonopermeabilization","publication_year":2008,"publication_date":"2008-12-01","ids":{"openalex":"https://openalex.org/W1997081962","doi":"https://doi.org/10.1007/s10396-008-0195-x","mag":"1997081962","pmid":"https://pubmed.ncbi.nlm.nih.gov/27278987"},"language":"en","primary_location":{"id":"doi:10.1007/s10396-008-0195-x","doi":"https://doi.org/10.1007/s10396-008-0195-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10396-008-0195-x","pdf_url":null,"source":{"id":"https://openalex.org/S80821584","display_name":"Journal of Medical Ultrasonics","issn_l":"1346-4523","issn":["1346-4523","1613-2254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Ultrasonics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070346237","display_name":"Loreto B. Feril","orcid":"https://orcid.org/0000-0001-8633-8835","observed_orcids":["https://orcid.org/0000-0001-8633-8835"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Loreto B. Feril","raw_affiliation_strings":["Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan. feril@fukuoka-u.ac.jp","Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan. feril@fukuoka-u.ac.jp","institution_ids":["https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054073636","display_name":"Katsuro Tachibana","orcid":"https://orcid.org/0000-0002-8514-696X","observed_orcids":["https://orcid.org/0000-0002-8514-696X"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuro Tachibana","raw_affiliation_strings":["Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020437138","display_name":"Yurika Ikeda-Dantsuji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yurika Ikeda-Dantsuji","raw_affiliation_strings":["Department of Microbiology and Immunology, Fukuoka University School of Medicine, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Fukuoka University School of Medicine, Fukuoka, Japan","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110086875","display_name":"Hitomi Endo","orcid":"https://orcid.org/0009-0006-6471-2201","observed_orcids":["https://orcid.org/0009-0006-6471-2201"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitomi Endo","raw_affiliation_strings":["Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yoshimi Harada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshimi Harada","raw_affiliation_strings":["Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Fukuoka University School of Medicine, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111741903","display_name":"Takashi Kondo","orcid":"https://orcid.org/0000-0002-1948-9331","observed_orcids":["https://orcid.org/0000-0002-1948-9331"]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Kondo","raw_affiliation_strings":["Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan","institution_ids":["https://openalex.org/I42766147"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102907821","display_name":"Ryohei Ogawa","orcid":"https://orcid.org/0000-0001-8092-3785","observed_orcids":["https://orcid.org/0000-0001-8092-3785"]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryohei Ogawa","raw_affiliation_strings":["Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan","institution_ids":["https://openalex.org/I42766147"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070346237"],"corresponding_institution_ids":["https://openalex.org/I31784960"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.0249,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.04712042,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"35","issue":"4","first_page":"161","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/low-intensity-ultrasound","display_name":"low-intensity ultrasound","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ultrasound-mediated-gene-transfection","display_name":"ultrasound-mediated gene transfection","score":0.824999988079071},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.43299999833106995},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.6449999809265137},{"id":"https://openalex.org/keywords/sonodynamic-therapy","display_name":"sonodynamic therapy","score":0.9409999847412109},{"id":"https://openalex.org/keywords/therapeutic-ultrasound","display_name":"ultrasound therapy","score":0.5059999823570251}],"concepts":[{"id":"https://openalex.org/C2778448707","wikidata":"https://www.wikidata.org/wiki/Q7562147","display_name":"Sonodynamic therapy","level":3,"score":0.8828988075256348},{"id":"https://openalex.org/C2779727089","wikidata":"https://www.wikidata.org/wiki/Q564875","display_name":"Therapeutic ultrasound","level":3,"score":0.6339654326438904},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.5653817057609558},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5346628427505493},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.5136362910270691},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.49353110790252686},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4200291633605957},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4121474623680115},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3982551395893097},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.39025774598121643},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.36316436529159546},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3555915355682373},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3386538028717041},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33361494541168213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3127173185348511},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.20770993828773499},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.11610031127929688},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11144664883613586}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s10396-008-0195-x","doi":"https://doi.org/10.1007/s10396-008-0195-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10396-008-0195-x","pdf_url":null,"source":{"id":"https://openalex.org/S80821584","display_name":"Journal of Medical Ultrasonics","issn_l":"1346-4523","issn":["1346-4523","1613-2254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Ultrasonics","raw_type":"journal-article"},{"id":"pmid:27278987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27278987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical ultrasonics (2001)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W1497244716","https://openalex.org/W1529623919","https://openalex.org/W1543133300","https://openalex.org/W1577694822","https://openalex.org/W1968338138","https://openalex.org/W1973493114","https://openalex.org/W1974073207","https://openalex.org/W1975479735","https://openalex.org/W1978397527","https://openalex.org/W1981293537","https://openalex.org/W1981953976","https://openalex.org/W1981991254","https://openalex.org/W1985749510","https://openalex.org/W1988157065","https://openalex.org/W1988363709","https://openalex.org/W1993146119","https://openalex.org/W1995191681","https://openalex.org/W1996833785","https://openalex.org/W1998220101","https://openalex.org/W1999207794","https://openalex.org/W2006811974","https://openalex.org/W2008033591","https://openalex.org/W2009082552","https://openalex.org/W2009322449","https://openalex.org/W2012411919","https://openalex.org/W2014926635","https://openalex.org/W2015814020","https://openalex.org/W2020914390","https://openalex.org/W2025071069","https://openalex.org/W2026432837","https://openalex.org/W2026486556","https://openalex.org/W2029765361","https://openalex.org/W2038753313","https://openalex.org/W2038832028","https://openalex.org/W2041834445","https://openalex.org/W2041973026","https://openalex.org/W2042315524","https://openalex.org/W2043902038","https://openalex.org/W2044071797","https://openalex.org/W2051795777","https://openalex.org/W2052301847","https://openalex.org/W2053639622","https://openalex.org/W2061801043","https://openalex.org/W2063862445","https://openalex.org/W2066249725","https://openalex.org/W2066585305","https://openalex.org/W2067653965","https://openalex.org/W2067879263","https://openalex.org/W2068139620","https://openalex.org/W2068517324","https://openalex.org/W2070289031","https://openalex.org/W2070683761","https://openalex.org/W2076148822","https://openalex.org/W2079987784","https://openalex.org/W2084646493","https://openalex.org/W2085187685","https://openalex.org/W2085755264","https://openalex.org/W2087382161","https://openalex.org/W2089828109","https://openalex.org/W2090147784","https://openalex.org/W2091306126","https://openalex.org/W2105742456","https://openalex.org/W2106929287","https://openalex.org/W2123141942","https://openalex.org/W2125801746","https://openalex.org/W2136479202","https://openalex.org/W2138227433","https://openalex.org/W2138766402","https://openalex.org/W2149492643","https://openalex.org/W2150009395","https://openalex.org/W2155750504","https://openalex.org/W2155990691","https://openalex.org/W2159185120","https://openalex.org/W2168708851","https://openalex.org/W2341532553"],"related_works":["https://openalex.org/W2076148822","https://openalex.org/W2053862489","https://openalex.org/W2413386865","https://openalex.org/W2009322449","https://openalex.org/W7024649333","https://openalex.org/W2533400607","https://openalex.org/W2143587404","https://openalex.org/W1979377589","https://openalex.org/W2015814020","https://openalex.org/W2155750504"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}