{"id":"https://openalex.org/W1997006005","doi":"https://doi.org/10.1159/000113696","title":"Functional Genomics Dissects Pathomechanisms in Tauopathies: Mitosis Failure and Unfolded Protein Response","display_name":"Functional Genomics Dissects Pathomechanisms in Tauopathies: Mitosis Failure and Unfolded Protein Response","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W1997006005","doi":"https://doi.org/10.1159/000113696","mag":"1997006005","pmid":"https://pubmed.ncbi.nlm.nih.gov/18322384"},"language":"en","primary_location":{"id":"doi:10.1159/000113696","doi":"https://doi.org/10.1159/000113696","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000113696","pdf_url":null,"source":{"id":"https://openalex.org/S101887095","display_name":"Neurodegenerative Diseases","issn_l":"1660-2854","issn":["1660-2854","1660-2862"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurodegenerative Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045325665","display_name":"J\u00fcrgen G\u00f6tz","orcid":"https://orcid.org/0000-0001-8501-7896","observed_orcids":["https://orcid.org/0000-0001-8501-7896","https://orcid.org/0000-0002-2003-9135"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"J\u00fcrgen G\u00f6tz","raw_affiliation_strings":["Alzheimer's and Parkinson's Disease Laboratory, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia. jgoetz@med.usyd.edu.au","Alzheimer's and Parkinson's Disease Laboratory, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Parkinson's Disease Laboratory, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia. jgoetz@med.usyd.edu.au","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"Alzheimer's and Parkinson's Disease Laboratory, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081218491","display_name":"Della C. David","orcid":"https://orcid.org/0000-0001-8597-9470","observed_orcids":["https://orcid.org/0000-0001-8597-9470"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Della David","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052572680","display_name":"Fr\u00e9d\u00e9ric J. Hoerndli","orcid":"https://orcid.org/0000-0001-6838-0386","observed_orcids":["https://orcid.org/0000-0001-6838-0386"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Frederic Hoerndli","raw_affiliation_strings":["Univ. of Zurich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Zurich","institution_ids":["https://openalex.org/I202697423"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030210067","display_name":"Yazi Diana Ke","orcid":"https://orcid.org/0000-0002-1423-0451","observed_orcids":["https://orcid.org/0000-0002-1423-0451"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Yazi D. Ke","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021245416","display_name":"Nicole Sch\u00f6nrock","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Nicole Schonrock","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andreas Wiesner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Andreas Wiesner","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062184288","display_name":"Thomas Fath","orcid":"https://orcid.org/0000-0002-6877-7567","observed_orcids":["https://orcid.org/0000-0002-6877-7567"]},"institutions":[{"id":"https://openalex.org/I2802384191","display_name":"Children's Hospital at Westmead","ror":"https://ror.org/05k0s5494","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2802384191"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Thomas Fath","raw_affiliation_strings":["Children's Hospital at Westmead, NSW"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital at Westmead, NSW","institution_ids":["https://openalex.org/I2802384191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042988931","display_name":"Laita Bokhari","orcid":"https://orcid.org/0000-0003-4522-2611","observed_orcids":["https://orcid.org/0000-0003-4522-2611"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Laita Bokhari","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111566052","display_name":"Yun-An Lim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Yun-An Lim","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060523292","display_name":"Natasha A. Deters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Natasha Deters","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073763982","display_name":"Lars Matthias Ittner","orcid":"https://orcid.org/0000-0001-6738-3825","observed_orcids":["https://orcid.org/0000-0001-6738-3825"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Lars M. Ittner","raw_affiliation_strings":["University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7499,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.64341863,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"5","issue":"3-4","first_page":"179","last_page":"181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8740000128746033},{"id":"https://openalex.org/keywords/tauopathy","display_name":"tauopathy","score":0.9380000233650208},{"id":"https://openalex.org/keywords/amyloid-beta-1-42","display_name":"amyloid-beta 42","score":0.8870000243186951},{"id":"https://openalex.org/keywords/unfolded-protein-response","display_name":"unfolded protein response","score":0.9520000219345093},{"id":"https://openalex.org/keywords/endoplasmic-reticulum-stress","display_name":"endoplasmic reticulum stress","score":0.968999981880188},{"id":"https://openalex.org/keywords/valosin-containing-protein","display_name":"VCP","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cell-cycle-re-entry","display_name":"cell cycle re-entry","score":0.6790000200271606},{"id":"https://openalex.org/keywords/postmitotic-neurons","display_name":"postmitotic neurons","score":0.8140000104904175},{"id":"https://openalex.org/keywords/neuronal-apoptosis","display_name":"neuronal apoptosis","score":0.6679999828338623},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.6549999713897705},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.9039999842643738},{"id":"https://openalex.org/keywords/sh-sy5y-cells","display_name":"SH-SY5Y cells","score":0.7990000247955322},{"id":"https://openalex.org/keywords/amygdala","display_name":"amygdala","score":0.7020000219345093},{"id":"https://openalex.org/keywords/transcriptomics","display_name":"transcriptomics","score":0.5120000243186951},{"id":"https://openalex.org/keywords/proteomics","display_name":"proteomics","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.532547652721405},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.44988539814949036},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.4415556788444519},{"id":"https://openalex.org/C139447449","wikidata":"https://www.wikidata.org/wiki/Q14633900","display_name":"Unfolded protein response","level":3,"score":0.4405099153518677},{"id":"https://openalex.org/C2778670691","wikidata":"https://www.wikidata.org/wiki/Q419507","display_name":"Tau protein","level":4,"score":0.4379183351993561},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4322627782821655},{"id":"https://openalex.org/C31705614","wikidata":"https://www.wikidata.org/wiki/Q423510","display_name":"Amyloid precursor protein","level":4,"score":0.43108734488487244},{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.4205712378025055},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35407987236976624},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33521100878715515},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.30289626121520996},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.26105839014053345},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22017687559127808},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20767197012901306},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20423802733421326},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13675367832183838},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1159/000113696","doi":"https://doi.org/10.1159/000113696","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000113696","pdf_url":null,"source":{"id":"https://openalex.org/S101887095","display_name":"Neurodegenerative Diseases","issn_l":"1660-2854","issn":["1660-2854","1660-2862"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurodegenerative Diseases","raw_type":"journal-article"},{"id":"pmid:18322384","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18322384","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro-degenerative diseases","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1979481666","https://openalex.org/W1985659039","https://openalex.org/W1989146486","https://openalex.org/W1999486930","https://openalex.org/W2033607340","https://openalex.org/W2035470211","https://openalex.org/W2102102358","https://openalex.org/W2105704879","https://openalex.org/W2134183468","https://openalex.org/W2136673626"],"related_works":["https://openalex.org/W1979481666","https://openalex.org/W2036731385","https://openalex.org/W2033607340","https://openalex.org/W2142836511","https://openalex.org/W1981829508","https://openalex.org/W2954596963","https://openalex.org/W2783356419","https://openalex.org/W1571408826","https://openalex.org/W4391917256","https://openalex.org/W2973426571"],"abstract_inverted_index":{"BACKGROUND:":[0],"Alzheimer's":[1],"disease":[2],"(AD)":[3],"is":[4],"characterized":[5],"by":[6,62,75],"beta-amyloid":[7],"(Abeta)":[8],"peptide-containing":[9],"plaques":[10],"and":[11,41,71,78,97,108,119,147],"tau-containing":[12],"neurofibrillary":[13],"tangles.":[14],"By":[15],"intracerebral":[16],"injection":[17],"of":[18,49,80,122,132,159,193,204],"Abeta(42),":[19],"both":[20,39,136],"pathologies":[21],"have":[22,171],"been":[23,173],"combined":[24],"in":[25,31,88,135,169,206],"P301L":[26,65,98,115,124],"tau":[27,36,43,99],"mutant":[28,42,66],"mice.":[29],"Furthermore,":[30,198],"cell":[32,91,106,109,190],"culture,":[33],"Abeta(42)":[34,40,63,96,205],"induces":[35,196],"aggregation.":[37],"While":[38],"cause":[44],"neuronal":[45],"dysfunction,":[46],"their":[47],"modes":[48],"action":[50],"are":[51,60],"only":[52],"vaguely":[53],"understood.":[54],"METHODS:":[55],"To":[56],"determine":[57],"which":[58],"processes":[59],"disrupted":[61],"and/or":[64],"tau,":[67],"we":[68],"used":[69],"transcriptomic":[70,86],"proteomic":[72],"techniques":[73],"followed":[74],"functional":[76,142],"validation":[77],"analysis":[79],"human":[81],"AD":[82],"tissue.":[83],"RESULTS:":[84],"Our":[85,179],"study":[87],"the":[89,105,120,140,150,160,182,207],"SH-SY5Y":[90,117],"culture":[92],"system":[93,163],"revealed":[94,127],"that":[95,128,186,188],"expression":[100],"independently":[101],"affect":[102],"genes":[103],"controlling":[104],"cycle":[107,191],"proliferation.":[110],"Proteomics":[111],"applied":[112],"to":[113,139,175],"Abeta(42)-treated":[114],"tau-expressing":[116],"cells":[118],"amygdala":[121],"Abeta(42)-injected":[123],"transgenic":[125],"mice":[126],"a":[129,157,202],"significant":[130],"fraction":[131],"proteins":[133,151],"altered":[134],"systems":[137],"belonged":[138],"same":[141],"categories,":[143],"i.e.":[144],"stress":[145,208],"response":[146,209],"metabolism.":[148],"Among":[149],"identified":[152],"was":[153],"valosin-containing":[154],"protein":[155,212],"(VCP),":[156],"component":[158],"quality":[161],"control":[162],"during":[164],"endoplasmic":[165],"reticulum":[166],"stress.":[167],"Mutations":[168],"VCP":[170],"recently":[172],"linked":[174],"frontotemporal":[176],"dementia.":[177],"CONCLUSION:":[178],"data":[180,200],"support":[181],"mitosis":[183],"failure":[184],"hypothesis":[185],"claims":[187],"aberrant":[189],"reentry":[192],"postmitotic":[194],"neurons":[195],"apoptosis.":[197],"our":[199],"underline":[201],"role":[203],"associated":[210],"with":[211],"folding.":[213]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}