{"id":"https://openalex.org/W1996958196","doi":"https://doi.org/10.1002/eji.200535349","title":"Immunoadsorption against two distinct epitopes on human type XVII collagen abolishes dermal\u2010epidermal separation induced in vitro by autoantibodies from pemphigoid gestationis patients","display_name":"Immunoadsorption against two distinct epitopes on human type XVII collagen abolishes dermal\u2010epidermal separation induced in vitro by autoantibodies from pemphigoid gestationis patients","publication_year":2006,"publication_date":"2006-03-21","ids":{"openalex":"https://openalex.org/W1996958196","doi":"https://doi.org/10.1002/eji.200535349","mag":"1996958196","pmid":"https://pubmed.ncbi.nlm.nih.gov/16552711"},"language":"en","primary_location":{"id":"doi:10.1002/eji.200535349","doi":"https://doi.org/10.1002/eji.200535349","is_oa":true,"landing_page_url":"https://doi.org/10.1002/eji.200535349","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.200535349","source":{"id":"https://openalex.org/S126191069","display_name":"European Journal of Immunology","issn_l":"0014-2980","issn":["0014-2980","1521-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.200535349","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113572680","display_name":"Josep E. Herrero\u2010Gonz\u00e1lez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]},{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Josep\u2004E. Herrero\u2010Gonz\u00e1lez","raw_affiliation_strings":["Department of Dermatology, University of L\u00fcbeck, L\u00fcbeck, Germany","Department of Dermatology, University of W\u00fcrzburg, W\u00fcrzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of L\u00fcbeck, L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]},{"raw_affiliation_string":"Department of Dermatology, University of W\u00fcrzburg, W\u00fcrzburg, Germany","institution_ids":["https://openalex.org/I25974101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006480241","display_name":"Olaf Brauns","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olaf Brauns","raw_affiliation_strings":["Fresenius Medical Care Affina GmbH, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fresenius Medical Care Affina GmbH, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015380273","display_name":"Ralf Egner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ralf Egner","raw_affiliation_strings":["Fresenius Medical Care Affina GmbH, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fresenius Medical Care Affina GmbH, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025000440","display_name":"Wolfgang R\u00f6nspeck","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wolfgang R\u00f6nspeck","raw_affiliation_strings":["Fresenius Medical Care Affina GmbH, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fresenius Medical Care Affina GmbH, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020138183","display_name":"Jos\u00e9 Manuel Mascar\u00f3","orcid":"https://orcid.org/0000-0001-9327-2555","observed_orcids":["https://orcid.org/0000-0001-9327-2555"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9\u2004M. Mascar\u00f3","raw_affiliation_strings":["Department of Dermatology, Hospital Cli\u0301nic, University of Barcelona, Barcelona, Spain","Department of Dermatology, Hospital Cl\u00ednic University of Barcelona Barcelona Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Hospital Cli\u0301nic, University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I71999127"]},{"raw_affiliation_string":"Department of Dermatology, Hospital Cl\u00ednic University of Barcelona Barcelona Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083484570","display_name":"Marcel F. Jonkman","orcid":"https://orcid.org/0000-0002-8471-9340","observed_orcids":["https://orcid.org/0000-0002-8471-9340"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marcel\u2004F. Jonkman","raw_affiliation_strings":["Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands","Translational Immunology Groningen (TRIGR)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Translational Immunology Groningen (TRIGR)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090549024","display_name":"Detlef Zillikens","orcid":"https://orcid.org/0000-0002-5668-307X","observed_orcids":["https://orcid.org/0000-0002-5668-307X"]},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Detlef Zillikens","raw_affiliation_strings":["Department of Dermatology, University of Lu\u0308beck, Lu\u0308beck, Germany","Department of Dermatology; University of L\u00fcbeck; L\u00fcbeck, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Lu\u0308beck, Lu\u0308beck, Germany","institution_ids":["https://openalex.org/I9341345"]},{"raw_affiliation_string":"Department of Dermatology; University of L\u00fcbeck; L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048808069","display_name":"Cassian Sitaru","orcid":"https://orcid.org/0000-0002-0370-1270","observed_orcids":["https://orcid.org/0000-0002-0370-1270"]},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Cassian Sitaru","raw_affiliation_strings":["Department of Dermatology, University of Lu\u0308beck, Lu\u0308beck, Germany","Department of Dermatology; University of L\u00fcbeck; L\u00fcbeck, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Lu\u0308beck, Lu\u0308beck, Germany","institution_ids":["https://openalex.org/I9341345"]},{"raw_affiliation_string":"Department of Dermatology; University of L\u00fcbeck; L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5048808069"],"corresponding_institution_ids":["https://openalex.org/I9341345"],"apc_list":{"value":4550,"currency":"USD","value_usd":4550},"apc_paid":null,"fwci":4.1188,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":{"value":0.93187383,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"36","issue":"4","first_page":"1039","last_page":"1048"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11730","display_name":"Autoimmune Bullous Skin Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11730","display_name":"Autoimmune Bullous Skin Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pemphigoid-gestationis","display_name":"pemphigoid gestationis","score":1.0},{"id":"https://openalex.org/keywords/type-xvii-collagen","display_name":"collagen XVII","score":0.9620000123977661},{"id":"https://openalex.org/keywords/bp180","display_name":"BP180","score":0.9959999918937683},{"id":"https://openalex.org/keywords/autoantibodies","display_name":"autoantibodies","score":0.8730000257492065},{"id":"https://openalex.org/keywords/epitope-mapping","display_name":"epitope mapping","score":0.8550000190734863},{"id":"https://openalex.org/keywords/immunoadsorption","display_name":"immunoadsorption","score":0.8550000190734863},{"id":"https://openalex.org/keywords/dermal-epidermal-separation","display_name":"dermal-epidermal separation","score":0.9890000224113464},{"id":"https://openalex.org/keywords/autoimmune-blistering-disease","display_name":"autoimmune blistering disease","score":0.7850000262260437},{"id":"https://openalex.org/keywords/hemidesmosomes","display_name":"hemidesmosomes","score":0.8510000109672546},{"id":"https://openalex.org/keywords/antigen-specific-immunotherapy","display_name":"antigen-specific immunotherapy","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.9174449443817139},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.8593944311141968},{"id":"https://openalex.org/C2779839709","wikidata":"https://www.wikidata.org/wiki/Q1660148","display_name":"Immunoadsorption","level":3,"score":0.6426140666007996},{"id":"https://openalex.org/C2779252107","wikidata":"https://www.wikidata.org/wiki/Q1004647","display_name":"Bullous pemphigoid","level":3,"score":0.5659416913986206},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5185645222663879},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5065411329269409},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49193668365478516},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.48951447010040283},{"id":"https://openalex.org/C2778075117","wikidata":"https://www.wikidata.org/wiki/Q881811","display_name":"Pemphigoid","level":4,"score":0.48442795872688293},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4611530303955078},{"id":"https://openalex.org/C2781241564","wikidata":"https://www.wikidata.org/wiki/Q1347450","display_name":"Epitope mapping","level":4,"score":0.4254942536354065},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3665512204170227},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32496383786201477},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14803650975227356}],"mesh":[{"descriptor_ui":"D000918","descriptor_name":"Antibody Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004817","descriptor_name":"Epidermis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004817","descriptor_name":"Epidermis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006559","descriptor_name":"Pemphigoid Gestationis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006559","descriptor_name":"Pemphigoid Gestationis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007163","descriptor_name":"Immunosorbent Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020405","descriptor_name":"Dermis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020405","descriptor_name":"Dermis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D043170","descriptor_name":"Collagen Type XVIII","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043170","descriptor_name":"Collagen Type XVIII","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1002/eji.200535349","doi":"https://doi.org/10.1002/eji.200535349","is_oa":true,"landing_page_url":"https://doi.org/10.1002/eji.200535349","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.200535349","source":{"id":"https://openalex.org/S126191069","display_name":"European Journal of Immunology","issn_l":"0014-2980","issn":["0014-2980","1521-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:16552711","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16552711","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of immunology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.571.8983","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.571.8983","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://csitaru.fastmail.fm/Herrero-Gonzales-EurJImmunol-2006.pdf","raw_type":"text"},{"id":"pmh:oai:pure.rug.nl:openaire_cris_publications/19fdeaff-7038-4810-8e4b-98f25b60374a","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11370/19fdeaff-7038-4810-8e4b-98f25b60374a","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Herrero-Gonzalez, JE, Brauns, O, Egner, R, Ronspeck, W, Mascaro, JM, Jonkman, MF, Zillikens, D & Sitaru, C 2006, 'Immunoadsorption against two distinct epitopes on human type XVII collagen abolishes dermal-epidermal separation induced in vitro by autoantibodies from pemphigoid gestationis patients', European Journal of Immunology, vol. 36, no. 4, pp. 1039-1048. https://doi.org/10.1002/eji.200535349","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/19fdeaff-7038-4810-8e4b-98f25b60374a","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/19fdeaff-7038-4810-8e4b-98f25b60374a","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Immunology, 36(4), 1039 - 1048. Wiley","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1002/eji.200535349","doi":"https://doi.org/10.1002/eji.200535349","is_oa":true,"landing_page_url":"https://doi.org/10.1002/eji.200535349","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.200535349","source":{"id":"https://openalex.org/S126191069","display_name":"European Journal of Immunology","issn_l":"0014-2980","issn":["0014-2980","1521-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321672","display_name":"Else Kr\u00f6ner-Fresenius-Stiftung","ror":"https://ror.org/03zcxha54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1996958196.pdf","grobid_xml":"https://content.openalex.org/works/W1996958196.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W70790455","https://openalex.org/W1541346415","https://openalex.org/W1578839038","https://openalex.org/W1584863617","https://openalex.org/W1602264889","https://openalex.org/W1814199953","https://openalex.org/W1927348210","https://openalex.org/W1967402284","https://openalex.org/W1967774913","https://openalex.org/W1976323372","https://openalex.org/W1978444795","https://openalex.org/W1982922358","https://openalex.org/W1992231692","https://openalex.org/W1992808224","https://openalex.org/W1998843997","https://openalex.org/W2001412659","https://openalex.org/W2002282183","https://openalex.org/W2005613711","https://openalex.org/W2012216540","https://openalex.org/W2031921930","https://openalex.org/W2038701140","https://openalex.org/W2041827428","https://openalex.org/W2046603954","https://openalex.org/W2055590566","https://openalex.org/W2058792960","https://openalex.org/W2072316300","https://openalex.org/W2074440379","https://openalex.org/W2075511268","https://openalex.org/W2080335580","https://openalex.org/W2083948274","https://openalex.org/W2085513714","https://openalex.org/W2085945132","https://openalex.org/W2089524261","https://openalex.org/W2093948126","https://openalex.org/W2098892892","https://openalex.org/W2109963121","https://openalex.org/W2135386059","https://openalex.org/W2165576720","https://openalex.org/W4243974294","https://openalex.org/W4248115658","https://openalex.org/W4248405776"],"related_works":["https://openalex.org/W7070101852","https://openalex.org/W2588362902","https://openalex.org/W7096180841","https://openalex.org/W2507303402","https://openalex.org/W2051971370","https://openalex.org/W2041984932","https://openalex.org/W2093443868","https://openalex.org/W3194373564","https://openalex.org/W2524897419","https://openalex.org/W2045628845"],"abstract_inverted_index":{"Pemphigoid":[0],"gestationis":[1],"(PG)":[2],"is":[3],"a":[4,79],"subepidermal":[5],"autoimmune":[6],"blistering":[7],"disease":[8],"characterized":[9],"by":[10,59,133],"self-reactive":[11],"T":[12,26],"and":[13,27,116,147],"B":[14,28],"cells":[15],"specific":[16],"for":[17,142,157],"the":[18,34,48,54,83,87,111,139,150],"transmembrane":[19],"hemidesmosomal":[20],"protein":[21],"type":[22,42],"XVII":[23,43],"collagen/BP180.":[24],"Major":[25],"cell":[29],"epitopes":[30,57,109,127,140],"are":[31],"located":[32],"within":[33,110],"immunodominant":[35],"16th":[36],"non-collagenous":[37],"domain":[38],"A":[39],"(NC16A)":[40],"of":[41,47,72,82,90,152],"collagen.":[44],"The":[45],"aim":[46],"present":[49],"study":[50,137],"was":[51],"to":[52,106],"map":[53],"pathogenically":[55],"relevant":[56,141],"targeted":[58],"blister-inducing":[60,88],"patients'":[61],"autoantibodies.":[62,135],"For":[63],"this":[64,158],"purpose,":[65],"we":[66,100],"used":[67],"an":[68,122,153],"in":[69,145],"vitro":[70],"model":[71],"autoantibody-induced":[73],"leukocyte-dependent":[74],"dermal-epidermal":[75,130],"separation.":[76],"Pre-adsorption":[77],"against":[78],"recombinant":[80],"form":[81],"NC16A":[84,112],"region":[85,113],"abolished":[86,129],"potential":[89],"autoantibodies":[91,104],"from":[92],"all":[93],"PG":[94,103,134,146],"patients.":[95],"Using":[96],"overlapping":[97],"synthetic":[98],"peptides,":[99],"demonstrated":[101],"that":[102],"bind":[105],"two":[107],"defined":[108],"(aa":[114],"500-514":[115],"aa":[117],"511-523).":[118],"Importantly,":[119],"pre-adsorption":[120],"using":[121],"affinity":[123],"matrix":[124],"containing":[125],"these":[126],"completely":[128],"separation":[131],"induced":[132],"This":[136],"identifies":[138],"blister":[143],"induction":[144],"should":[148],"facilitate":[149],"development":[151],"antigen-specific":[154],"immunoadsorption":[155],"therapy":[156],"disease.":[159]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}