{"id":"https://openalex.org/W199693028","doi":"https://doi.org/10.33588/rn.3306.2001146","title":"Trastornos neuropsiqui\u00e1tricos en la esclerosis m\u00faltiple","display_name":"Trastornos neuropsiqui\u00e1tricos en la esclerosis m\u00faltiple","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W199693028","doi":"https://doi.org/10.33588/rn.3306.2001146","mag":"199693028","pmid":"https://pubmed.ncbi.nlm.nih.gov/11727241"},"language":"es","primary_location":{"id":"doi:10.33588/rn.3306.2001146","doi":"https://doi.org/10.33588/rn.3306.2001146","is_oa":false,"landing_page_url":"https://doi.org/10.33588/rn.3306.2001146","pdf_url":null,"source":{"id":"https://openalex.org/S184263677","display_name":"Revista de Neurolog\u00eda","issn_l":"0210-0010","issn":["0210-0010","1576-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322632785","host_organization_name":"Viguera Publishers","host_organization_lineage":["https://openalex.org/P4322632785"],"host_organization_lineage_names":["Viguera Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Neurolog\u00eda","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045045115","display_name":"J M Garc\u00eda-Moreno","orcid":"https://orcid.org/0000-0001-8270-2580","observed_orcids":["https://orcid.org/0000-0001-8270-2580"]},"institutions":[{"id":"https://openalex.org/I4210090436","display_name":"Hospital Universitario Virgen Macarena","ror":"https://ror.org/016p83279","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210090436"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Manuel Garc\u00eda Moreno","raw_affiliation_strings":["Unidad de Esclerosis M\u00faltiple, Servicio de Neurolog\u00eda, Hospital Universitario Virgen Macarena, Sevilla, 41071, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unidad de Esclerosis M\u00faltiple, Servicio de Neurolog\u00eda, Hospital Universitario Virgen Macarena, Sevilla, 41071, Espa\u00f1a","institution_ids":["https://openalex.org/I4210090436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074131997","display_name":"Pablo Duque San Juan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pablo Duque San Juan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5038315518","display_name":"Guillermo Izquierdo Ayuso","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guillermo Izquierdo Ayuso","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4482,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.62234795,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"33","issue":"06","first_page":"560","last_page":"560"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":1.0},{"id":"https://openalex.org/keywords/neuropsychiatric-disorders","display_name":"neuropsychiatric disorders","score":0.984000027179718},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.8980000019073486},{"id":"https://openalex.org/keywords/mental-disorders","display_name":"mental illness","score":0.8059999942779541},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.8560000061988831},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.800000011920929},{"id":"https://openalex.org/keywords/neuropsychological-assessment","display_name":"neuropsychological assessment","score":0.8579999804496765},{"id":"https://openalex.org/keywords/neuropsychological-battery","display_name":"neuropsychological test battery","score":0.7870000004768372},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.8980000019073486},{"id":"https://openalex.org/keywords/treatment","display_name":"treatment","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.7970879673957825},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.7404720783233643},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5631023049354553},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5361402630805969},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4290010929107666},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.35317501425743103},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1325443685054779}],"mesh":[{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001523","descriptor_name":"Mental Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001523","descriptor_name":"Mental Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001523","descriptor_name":"Mental Disorders","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011613","descriptor_name":"Psychotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016899","descriptor_name":"Interferon-beta","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.33588/rn.3306.2001146","doi":"https://doi.org/10.33588/rn.3306.2001146","is_oa":false,"landing_page_url":"https://doi.org/10.33588/rn.3306.2001146","pdf_url":null,"source":{"id":"https://openalex.org/S184263677","display_name":"Revista de Neurolog\u00eda","issn_l":"0210-0010","issn":["0210-0010","1576-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322632785","host_organization_name":"Viguera Publishers","host_organization_lineage":["https://openalex.org/P4322632785"],"host_organization_lineage_names":["Viguera Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Neurolog\u00eda","raw_type":"journal-article"},{"id":"pmid:11727241","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11727241","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de neurologia","raw_type":"English Abstract"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2113339184","https://openalex.org/W149741596","https://openalex.org/W2092782883","https://openalex.org/W2772150232","https://openalex.org/W1593527468","https://openalex.org/W2467180315","https://openalex.org/W2406813457","https://openalex.org/W2070090862","https://openalex.org/W2343073533","https://openalex.org/W2493903301"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Neuropsychological":[1],"investigations":[2],"over":[3],"the":[4,10,33,50,67,82,100,129,160,169,176],"past":[5],"20":[6],"years":[7],"have":[8,95],"shown":[9],"high":[11],"prevalence":[12],"of":[13,36,49,54,76,88,125,131,149,165,178,181],"cognitive":[14,55,133],"dysfunction":[15],"in":[16,59,70,98,104,135,155,168],"multiple":[17,60,105,136,182],"sclerosis,":[18,61,106],"although":[19],"there":[20,107],"are":[21,108],"still":[22,109],"large":[23],"gaps.":[24],"In":[25],"this":[26],"article":[27],"we":[28,80],"review":[29,66],"current":[30,83],"concepts":[31],"regarding":[32],"different":[34],"types":[35,53],"neuropsychiatric":[37],"disorders,":[38],"their":[39,63],"physiopathology,":[40],"diagnosis":[41,156],"and":[42,56,62,74,157,162],"treatment.":[43],"DEVELOPMENT:":[44],"We":[45,65],"present":[46],"a":[47,117,120,147],"classification":[48],"most":[51],"important":[52],"psychiatric":[57],"alterations":[58],"physiopathology.":[64],"methods":[68],"used":[69],"diagnosis,":[71],"follow":[72],"up":[73],"assessment":[75],"these":[77,89],"patients.":[78],"Finally,":[79],"analyze":[81],"treatment":[84,177],"available":[85],"for":[86,119,128,171,175],"each":[87],"disorders.":[90],"CONCLUSIONS:":[91],"Although":[92],"considerable":[93],"advances":[94],"been":[96],"made":[97],"understanding":[99],"neuropsychological":[101,126],"disorders":[102,180],"occurring":[103],"many":[110],"questions":[111],"to":[112],"be":[113,142],"answered.":[114],"There":[115,144],"is":[116,145,184],"need":[118],"unified,":[121],"agreed,":[122],"validated":[123],"battery":[124],"tests":[127],"study":[130],"specific":[132],"deficits":[134],"sclerosis":[137,183],"so":[138],"that":[139],"results":[140],"may":[141],"compared.":[143],"also":[146],"lack":[148],"biological":[150],"markers":[151],"which":[152],"would":[153],"help":[154],"prognosis.":[158],"Finally":[159],"design":[161],"carrying":[163],"out":[164],"clinical":[166],"trials":[167],"search":[170],"specific,":[172],"effective":[173],"drugs":[174],"neuroconductual":[179],"necessary.":[185]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}