{"id":"https://openalex.org/W1996813232","doi":"https://doi.org/10.3347/kjp.2008.46.4.293","title":"Malondialdehyde, Glutathione, and Nitric Oxide Levels in Toxoplasma gondii Seropositive Patients","display_name":"Malondialdehyde, Glutathione, and Nitric Oxide Levels in Toxoplasma gondii Seropositive Patients","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W1996813232","doi":"https://doi.org/10.3347/kjp.2008.46.4.293","mag":"1996813232","pmid":"https://pubmed.ncbi.nlm.nih.gov/19127340","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2612619"},"language":"en","primary_location":{"id":"doi:10.3347/kjp.2008.46.4.293","doi":"https://doi.org/10.3347/kjp.2008.46.4.293","is_oa":true,"landing_page_url":"https://doi.org/10.3347/kjp.2008.46.4.293","pdf_url":"https://www.parahostdis.org/upload/pdf/kjp-46-293.pdf","source":{"id":"https://openalex.org/S94435289","display_name":"Korean Journal of Parasitology","issn_l":"0023-4001","issn":["0023-4001","1738-0006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319428","host_organization_name":"Korean Society for Parasitology","host_organization_lineage":["https://openalex.org/P4310319428"],"host_organization_lineage_names":["Korean Society for Parasitology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Korean Journal of Parasitology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.parahostdis.org/upload/pdf/kjp-46-293.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062566452","display_name":"\u00dclk\u00fc Karaman","orcid":"https://orcid.org/0000-0001-7027-1613","observed_orcids":["https://orcid.org/0000-0001-7027-1613"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ulku Karaman","raw_affiliation_strings":["Inonu University School of Medicine, Department of Parasitology, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inonu University School of Medicine, Department of Parasitology, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027845383","display_name":"Tuncay \u00c7elik","orcid":"https://orcid.org/0000-0001-6422-0350","observed_orcids":["https://orcid.org/0000-0001-6422-0350","https://orcid.org/0000-0002-2197-0079"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tuncay Celik","raw_affiliation_strings":["Inonu University School of Medicine, Department of Parasitology, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inonu University School of Medicine, Department of Parasitology, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074529579","display_name":"Tu\u011fba Raika K\u0131ran","orcid":"https://orcid.org/0000-0002-3724-0249","observed_orcids":["https://orcid.org/0000-0002-3724-0249"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tugba Raika Kiran","raw_affiliation_strings":["Inonu University School of Medicine, Department of Biochemistry and Clinical Biochemistry, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inonu University School of Medicine, Department of Biochemistry and Clinical Biochemistry, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042276658","display_name":"Cemil \u00c7olak","orcid":"https://orcid.org/0000-0001-5406-098X","observed_orcids":["https://orcid.org/0000-0001-5406-098X"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Cemil Colak","raw_affiliation_strings":["Firat University Department of Statistics, Elazig, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Firat University Department of Statistics, Elazig, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091572365","display_name":"Nilg\u00fcn Daldal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nilgun Ulfet Daldal","raw_affiliation_strings":["Inonu University School of Medicine, Department of Parasitology, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inonu University School of Medicine, Department of Parasitology, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.4623,"has_fulltext":true,"cited_by_count":71,"citation_normalized_percentile":{"value":0.91638664,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"46","issue":"4","first_page":"293","last_page":"293"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11155","display_name":"Toxoplasma gondii Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11155","display_name":"Toxoplasma gondii Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11154","display_name":"Parasitic infections in humans and animals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toxoplasma-gondii","display_name":"Toxoplasma gondii","score":0.9800000190734863},{"id":"https://openalex.org/keywords/toxoplasmosis","display_name":"toxoplasmosis","score":0.9710000157356262},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.9049999713897705},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9950000047683716},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8920000195503235},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.7879999876022339},{"id":"https://openalex.org/keywords/antioxidant-vitamins","display_name":"antioxidant vitamins","score":0.8669999837875366},{"id":"https://openalex.org/keywords/chronic-toxoplasmosis","display_name":"chronic toxoplasmosis","score":0.8889999985694885},{"id":"https://openalex.org/keywords/tissue-damage","display_name":"tissue damage","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.9491456747055054},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.8268165588378906},{"id":"https://openalex.org/C2778062946","wikidata":"https://www.wikidata.org/wiki/Q154878","display_name":"Toxoplasmosis","level":2,"score":0.7471081614494324},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.7079958915710449},{"id":"https://openalex.org/C2778128430","wikidata":"https://www.wikidata.org/wiki/Q131003","display_name":"Toxoplasma gondii","level":3,"score":0.643840491771698},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42092758417129517},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4191795587539673},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3980170488357544},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3235119879245758},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.2741760015487671},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.17784026265144348},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1695728898048401},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05147510766983032}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005978","descriptor_name":"Glutathione","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008315","descriptor_name":"Malondialdehyde","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014122","descriptor_name":"Toxoplasma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014123","descriptor_name":"Toxoplasmosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014123","descriptor_name":"Toxoplasmosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3347/kjp.2008.46.4.293","doi":"https://doi.org/10.3347/kjp.2008.46.4.293","is_oa":true,"landing_page_url":"https://doi.org/10.3347/kjp.2008.46.4.293","pdf_url":"https://www.parahostdis.org/upload/pdf/kjp-46-293.pdf","source":{"id":"https://openalex.org/S94435289","display_name":"Korean Journal of Parasitology","issn_l":"0023-4001","issn":["0023-4001","1738-0006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319428","host_organization_name":"Korean Society for Parasitology","host_organization_lineage":["https://openalex.org/P4310319428"],"host_organization_lineage_names":["Korean Society for Parasitology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Korean Journal of Parasitology","raw_type":"journal-article"},{"id":"pmid:19127340","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19127340","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Korean journal of parasitology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2612619","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2612619/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean J Parasitol","raw_type":"Text"},{"id":"pmh:oai:openaccess.firat.edu.tr:11508/44781","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.3347/kjp.2008.46.4.293","pdf_url":null,"source":{"id":"https://openalex.org/S4377196733","display_name":"DSpace - FIRAT (F\u0131rat University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143396566","host_organization_name":"F\u0131rat University","host_organization_lineage":["https://openalex.org/I143396566"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.3347/kjp.2008.46.4.293","doi":"https://doi.org/10.3347/kjp.2008.46.4.293","is_oa":true,"landing_page_url":"https://doi.org/10.3347/kjp.2008.46.4.293","pdf_url":"https://www.parahostdis.org/upload/pdf/kjp-46-293.pdf","source":{"id":"https://openalex.org/S94435289","display_name":"Korean Journal of Parasitology","issn_l":"0023-4001","issn":["0023-4001","1738-0006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319428","host_organization_name":"Korean Society for Parasitology","host_organization_lineage":["https://openalex.org/P4310319428"],"host_organization_lineage_names":["Korean Society for Parasitology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Korean Journal of Parasitology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1996813232.pdf","grobid_xml":"https://content.openalex.org/works/W1996813232.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1988148188","https://openalex.org/W1999256036","https://openalex.org/W2003158331","https://openalex.org/W2004253999","https://openalex.org/W2029144058","https://openalex.org/W2032961118","https://openalex.org/W2053054955","https://openalex.org/W2064413866","https://openalex.org/W2066490112","https://openalex.org/W2118161010","https://openalex.org/W2124890584","https://openalex.org/W2138749678","https://openalex.org/W2185161109","https://openalex.org/W2298428320"],"related_works":["https://openalex.org/W2730136140","https://openalex.org/W2959193337","https://openalex.org/W3036573378","https://openalex.org/W436911794","https://openalex.org/W4291312569","https://openalex.org/W2350668705","https://openalex.org/W2904515666","https://openalex.org/W4309029960","https://openalex.org/W3131481539","https://openalex.org/W3009677197"],"abstract_inverted_index":{"The":[0,124],"aim":[1],"of":[2,39,57,85,112,130,142,147,158],"this":[3,29],"study":[4],"was":[5,75,96],"to":[6,117],"investigate":[7],"the":[8,11,37,47,58,80,110,137,155],"difference":[9,74],"in":[10,36,46,65,83,93,115,145,166],"serum":[12],"malondialdehyde":[13],"(MDA),":[14],"glutathione":[15],"(GSH),":[16],"and":[17,24,33,43,79,88,100,132,161],"nitric":[18],"oxide":[19],"(NO)":[20],"levels":[21,35,102,134,157],"between":[22,77],"normal":[23],"T.":[25],"gondii-infected":[26],"patients.":[27],"To":[28],"end,":[30],"MDA,":[31,86,159],"GSH,":[32,87,160],"NO":[34,89,101,133,162],"sera":[38],"37":[40],"seropositive":[41],"patients":[42,78],"40":[44],"participants":[45],"control":[48,81,128],"group":[49,60,82],"were":[50,61],"evaluated.":[51],"In":[52],"Toxoplasma":[53],"ELISA,":[54],"IgG":[55],"results":[56],"patient":[59,156],"1,013.0":[62],"+/-":[63,69],"543.8":[64],"optical":[66],"density":[67],"(mean":[68],"SD).":[70],"A":[71,91],"statistically":[72],"significant":[73],"found":[76],"terms":[84],"levels.":[90],"decrease":[92],"GSH":[94],"activity":[95],"detected,":[97],"while":[98],"MDA":[99,131],"increased":[103],"significantly.":[104],"Consequently,":[105],"it":[106,151],"is":[107,152],"suggested":[108],"that":[109,154],"use":[111],"antioxidant":[113],"vitamins":[114],"addition":[116],"a":[118,140],"parasite":[119],"treatment":[120],"shall":[121],"prove":[122],"useful.":[123],"high":[125],"infection":[126],"vs":[127],"ratio":[129],"probably":[135],"suggests":[136],"occurrence":[138],"as":[139],"mechanism":[141],"tissue":[143],"damage":[144],"cases":[146],"chronic":[148],"toxoplasmosis.":[149,167],"Moreover,":[150],"recommended":[153],"should":[163],"be":[164],"evaluated":[165]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}