{"id":"https://openalex.org/W1996712946","doi":"https://doi.org/10.1007/bf02015417","title":"Microchemical studies on acid glycosaminoglycans of the epiphyseal zones during endochondral calcification","display_name":"Microchemical studies on acid glycosaminoglycans of the epiphyseal zones during endochondral calcification","publication_year":1973,"publication_date":"1973-12-01","ids":{"openalex":"https://openalex.org/W1996712946","doi":"https://doi.org/10.1007/bf02015417","mag":"1996712946","pmid":"https://pubmed.ncbi.nlm.nih.gov/4274646"},"language":"en","primary_location":{"id":"doi:10.1007/bf02015417","doi":"https://doi.org/10.1007/bf02015417","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02015417","pdf_url":null,"source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102165084","display_name":"Sven\u2010Erik Larsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sven-Erik Larsson","raw_affiliation_strings":["Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago, Illinois","The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois","Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago","The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111667909","display_name":"Robert D. Ray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert D. Ray","raw_affiliation_strings":["Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago, Illinois","The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois","Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago","The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108810478","display_name":"Klaus E. Kuettner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Klaus E. Kuettner","raw_affiliation_strings":["Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago, Illinois","The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois","Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago","The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Illinois at the Medical Center, Chicago","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"The Department of Orthopaedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago","institution_ids":["https://openalex.org/I1285301757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":null,"fwci":4.2727,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.94249569,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"13","issue":"1","first_page":"271","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acid-glycosaminoglycans","display_name":"acid glycosaminoglycans","score":0.996999979019165},{"id":"https://openalex.org/keywords/growth-plate","display_name":"growth plate","score":0.9110000133514404},{"id":"https://openalex.org/keywords/chondroitin-sulfate","display_name":"chondroitin sulfate","score":0.9570000171661377},{"id":"https://openalex.org/keywords/hyaluronic-acid","display_name":"hyaluronic acid","score":0.996999979019165},{"id":"https://openalex.org/keywords/proteoglycans","display_name":"proteoglycans","score":0.7760000228881836},{"id":"https://openalex.org/keywords/septal-cartilage","display_name":"septal cartilage","score":0.8569999933242798},{"id":"https://openalex.org/keywords/hypertrophic-chondrocytes","display_name":"hypertrophic chondrocytes","score":0.8410000205039978},{"id":"https://openalex.org/keywords/calcified-cartilage","display_name":"calcified cartilage","score":0.6740000247955322},{"id":"https://openalex.org/keywords/guanidine-hydrochloride-extraction","display_name":"guanidine hydrochloride extraction","score":0.7229999899864197},{"id":"https://openalex.org/keywords/molecular-weight-distribution","display_name":"molecular weight distribution","score":0.7239999771118164},{"id":"https://openalex.org/keywords/calf","display_name":"calf","score":0.5}],"concepts":[{"id":"https://openalex.org/C153074725","wikidata":"https://www.wikidata.org/wiki/Q407553","display_name":"Glycosaminoglycan","level":2,"score":0.8679957389831543},{"id":"https://openalex.org/C17938293","wikidata":"https://www.wikidata.org/wiki/Q3312710","display_name":"Endochondral ossification","level":3,"score":0.7318884134292603},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.729363739490509},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.7120106816291809},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6252073049545288},{"id":"https://openalex.org/C2777529286","wikidata":"https://www.wikidata.org/wiki/Q337231","display_name":"Hyaluronic acid","level":2,"score":0.6216438412666321},{"id":"https://openalex.org/C2776735749","wikidata":"https://www.wikidata.org/wiki/Q4862650","display_name":"Chondroitin","level":3,"score":0.5187414288520813},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.46864956617355347},{"id":"https://openalex.org/C2777917003","wikidata":"https://www.wikidata.org/wiki/Q500634","display_name":"Nasal septum","level":3,"score":0.43169906735420227},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3157368302345276},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2128244936466217},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21231096982955933},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08645251393318176},{"id":"https://openalex.org/C2778311950","wikidata":"https://www.wikidata.org/wiki/Q7363","display_name":"Nose","level":2,"score":0.06006664037704468}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002113","descriptor_name":"Calcification, Physiologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002807","descriptor_name":"Chondroitin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004838","descriptor_name":"Epiphyses","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006025","descriptor_name":"Glycosaminoglycans","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006820","descriptor_name":"Hyaluronic Acid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006984","descriptor_name":"Hypertrophy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009300","descriptor_name":"Nasal Septum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012540","descriptor_name":"Scapula","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02015417","doi":"https://doi.org/10.1007/bf02015417","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02015417","pdf_url":null,"source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue Research","raw_type":"journal-article"},{"id":"pmid:4274646","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4274646","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified tissue research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Life below water","id":"https://metadata.un.org/sdg/14","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W33496201","https://openalex.org/W1486185605","https://openalex.org/W1517129309","https://openalex.org/W1549718609","https://openalex.org/W1586971678","https://openalex.org/W1847714951","https://openalex.org/W1965665915","https://openalex.org/W1968474532","https://openalex.org/W1984093336","https://openalex.org/W1985698827","https://openalex.org/W2002133242","https://openalex.org/W2012528512","https://openalex.org/W2014665720","https://openalex.org/W2029163184","https://openalex.org/W2031420609","https://openalex.org/W2032682265","https://openalex.org/W2037877224","https://openalex.org/W2041428227","https://openalex.org/W2042930022","https://openalex.org/W2047244610","https://openalex.org/W2058553611","https://openalex.org/W2062075300","https://openalex.org/W2063180757","https://openalex.org/W2071406958","https://openalex.org/W2082637860","https://openalex.org/W2086930417","https://openalex.org/W2127608837","https://openalex.org/W2131989780","https://openalex.org/W2199747534","https://openalex.org/W2315819699","https://openalex.org/W2323908919","https://openalex.org/W2394731535","https://openalex.org/W2398098074","https://openalex.org/W2473640722","https://openalex.org/W3023826045","https://openalex.org/W4300936953"],"related_works":["https://openalex.org/W1979191919","https://openalex.org/W125271778","https://openalex.org/W2005511262","https://openalex.org/W2094122241","https://openalex.org/W2113015340","https://openalex.org/W2033063777","https://openalex.org/W2057877652","https://openalex.org/W2417036313","https://openalex.org/W2149708829","https://openalex.org/W2015855031"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}