{"id":"https://openalex.org/W1996586818","doi":"https://doi.org/10.1111/j.1572-0241.2008.01993.x","title":"Autologous Infusion of Expanded Mobilized Adult Bone Marrow-Derived CD34+ Cells Into Patients With Alcoholic Liver Cirrhosis","display_name":"Autologous Infusion of Expanded Mobilized Adult Bone Marrow-Derived CD34+ Cells Into Patients With Alcoholic Liver Cirrhosis","publication_year":2008,"publication_date":"2008-07-11","ids":{"openalex":"https://openalex.org/W1996586818","doi":"https://doi.org/10.1111/j.1572-0241.2008.01993.x","mag":"1996586818","pmid":"https://pubmed.ncbi.nlm.nih.gov/18637092"},"language":"en","primary_location":{"id":"doi:10.1111/j.1572-0241.2008.01993.x","doi":"https://doi.org/10.1111/j.1572-0241.2008.01993.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2008.01993.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104077917","display_name":"Madhava Pai","orcid":"https://orcid.org/0000-0003-1760-9632","observed_orcids":["https://orcid.org/0000-0003-1760-9632"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Madhava Pai","raw_affiliation_strings":["Department of Surgery, at Hammersmith Campus, Imperial College, London, United Kingdom","Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039213604","display_name":"Dimitris Zacharoulis","orcid":"https://orcid.org/0000-0002-8972-064X","observed_orcids":["https://orcid.org/0000-0002-8972-064X"]},"institutions":[{"id":"https://openalex.org/I145722265","display_name":"University of Thessaly","ror":"https://ror.org/04v4g9h31","country_code":"GR","type":"education","lineage":["https://openalex.org/I145722265"]},{"id":"https://openalex.org/I4210107217","display_name":"University Hospital of Larissa","ror":"https://ror.org/01s5dt366","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210107217"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitris Zacharoulis","raw_affiliation_strings":["Larissa Hospital, University of Thessaly, Larissa, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Larissa Hospital, University of Thessaly, Larissa, Greece","institution_ids":["https://openalex.org/I145722265","https://openalex.org/I4210107217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103477487","display_name":"Miroslav Mili\u0107evi\u0107","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4068193","display_name":"University of Belgrade","ror":"https://ror.org/02qsmb048","country_code":"RS","type":"education","lineage":["https://openalex.org/I4068193"]}],"countries":["RS"],"is_corresponding":false,"raw_author_name":"Miroslav N. Milicevic","raw_affiliation_strings":["Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia","Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia","institution_ids":["https://openalex.org/I4068193"]},{"raw_affiliation_string":"Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia; and","institution_ids":["https://openalex.org/I4068193"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050135978","display_name":"Salah Helmy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Salah Helmy","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069234120","display_name":"Long R. Jiao","orcid":"https://orcid.org/0000-0001-6774-4280","observed_orcids":["https://orcid.org/0000-0001-6774-4280"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Long R. Jiao","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075822134","display_name":"Nata\u0161a Levi\u010dar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nata\u0161a Levi\u010dar","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009045222","display_name":"Paul Tait","orcid":"https://orcid.org/0009-0009-2783-8069","observed_orcids":["https://orcid.org/0009-0009-2783-8069"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Tait","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael Scott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156194","display_name":"Addenbrooke's Hospital","ror":"https://ror.org/055vbxf86","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933","https://openalex.org/I4210156194"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Scott","raw_affiliation_strings":["Addenbrookes Hospital, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Addenbrookes Hospital, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I4210156194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111837468","display_name":"Stephen B. Marley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen B. Marley","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042855497","display_name":"Kevin Jestice","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156194","display_name":"Addenbrooke's Hospital","ror":"https://ror.org/055vbxf86","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933","https://openalex.org/I4210156194"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kevin Jestice","raw_affiliation_strings":["Addenbrookes Hospital, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Addenbrookes Hospital, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I4210156194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034508665","display_name":"Maria Glibeti\u0107","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4068193","display_name":"University of Belgrade","ror":"https://ror.org/02qsmb048","country_code":"RS","type":"education","lineage":["https://openalex.org/I4068193"]}],"countries":["RS"],"is_corresponding":false,"raw_author_name":"Maria Glibetic","raw_affiliation_strings":["Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia","Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia","institution_ids":["https://openalex.org/I4068193"]},{"raw_affiliation_string":"Institute of Digestive Diseases, University of Belgrade, Belgrade, Serbia; and","institution_ids":["https://openalex.org/I4068193"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027956350","display_name":"Devinder Singh Bansi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Devinder Bansi","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005117084","display_name":"Shahid Ahmed Khan","orcid":"https://orcid.org/0000-0003-2538-0911","observed_orcids":["https://orcid.org/0000-0003-2538-0911"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shahid A. Khan","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111829377","display_name":"Despina Kyriakou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145722265","display_name":"University of Thessaly","ror":"https://ror.org/04v4g9h31","country_code":"GR","type":"education","lineage":["https://openalex.org/I145722265"]},{"id":"https://openalex.org/I4210107217","display_name":"University Hospital of Larissa","ror":"https://ror.org/01s5dt366","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210107217"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Despina Kyriakou","raw_affiliation_strings":["Larissa Hospital, University of Thessaly, Larissa, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Larissa Hospital, University of Thessaly, Larissa, Greece","institution_ids":["https://openalex.org/I145722265","https://openalex.org/I4210107217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033927527","display_name":"Christos D. Rountas","orcid":"https://orcid.org/0000-0001-9295-8424","observed_orcids":["https://orcid.org/0000-0001-9295-8424"]},"institutions":[{"id":"https://openalex.org/I145722265","display_name":"University of Thessaly","ror":"https://ror.org/04v4g9h31","country_code":"GR","type":"education","lineage":["https://openalex.org/I145722265"]},{"id":"https://openalex.org/I4210107217","display_name":"University Hospital of Larissa","ror":"https://ror.org/01s5dt366","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210107217"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Christos Rountas","raw_affiliation_strings":["Larissa Hospital, University of Thessaly, Larissa, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Larissa Hospital, University of Thessaly, Larissa, Greece","institution_ids":["https://openalex.org/I145722265","https://openalex.org/I4210107217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037998112","display_name":"Andrew V. Thillainayagam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Thillainayagam","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105369941","display_name":"Joanna P. Nicholls","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Joanna P. Nicholls","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103741348","display_name":"Steen Lindkaer Jensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Steen Jensen","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074115908","display_name":"Jane F. Apperley","orcid":"https://orcid.org/0000-0002-1710-1794","observed_orcids":["https://orcid.org/0000-0002-1710-1794"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jane F. Apperley","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110414513","display_name":"Myrtle Y. Gordon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Myrtle Y. Gordon","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053323102","display_name":"Nagy Habib","orcid":"https://orcid.org/0000-0003-4920-4154","observed_orcids":["https://orcid.org/0000-0003-4920-4154"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nagy A. Habib","raw_affiliation_strings":["Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Hepatology, Haematology, and Radiology at Hammersmith Campus, Imperial College, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5053323102"],"corresponding_institution_ids":["https://openalex.org/I47508984"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":10.6921,"has_fulltext":false,"cited_by_count":218,"citation_normalized_percentile":{"value":0.98468313,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":100},"biblio":{"volume":"103","issue":"8","first_page":"1952","last_page":"1958"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.4323999881744385,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.4323999881744385,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.28859999775886536,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.11509999632835388,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alcoholic-cirrhosis","display_name":"alcoholic cirrhosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cd34-cells","display_name":"CD34+ cells","score":0.9290000200271606},{"id":"https://openalex.org/keywords/bone-marrow-derived-progenitor-cells","display_name":"bone marrow progenitor cells","score":0.7900000214576721},{"id":"https://openalex.org/keywords/g-csf-mobilization","display_name":"G-CSF mobilization","score":0.824999988079071},{"id":"https://openalex.org/keywords/hepatic-arterial-infusion","display_name":"hepatic artery infusion","score":0.7160000205039978},{"id":"https://openalex.org/keywords/cell-expansion","display_name":"cell expansion","score":0.675000011920929},{"id":"https://openalex.org/keywords/liver-function","display_name":"liver function","score":0.7350000143051147},{"id":"https://openalex.org/keywords/child-pugh-score","display_name":"Child-Pugh score","score":0.8859999775886536},{"id":"https://openalex.org/keywords/ascites","display_name":"ascites","score":0.6959999799728394},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9620504379272461},{"id":"https://openalex.org/C2777575235","wikidata":"https://www.wikidata.org/wiki/Q558404","display_name":"Alcoholic liver disease","level":3,"score":0.7862206101417542},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.7307809591293335},{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.6603236198425293},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.615450382232666},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.35970717668533325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35589033365249634},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.17237067222595215},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.04889947175979614},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007261","descriptor_name":"Infusions, Intra-Arterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008104","descriptor_name":"Liver Cirrhosis, Alcoholic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018952","descriptor_name":"Antigens, CD34","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019650","descriptor_name":"Hematopoietic Stem Cell Mobilization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053687","descriptor_name":"Adult Stem Cells","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1572-0241.2008.01993.x","doi":"https://doi.org/10.1111/j.1572-0241.2008.01993.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2008.01993.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:18637092","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18637092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Clinical Trial"},{"id":"pmh:oai:ir.lib.uth.gr:11615/31528","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11615/31528","pdf_url":null,"source":{"id":"https://openalex.org/S4306400243","display_name":"University of Thessaly Institutional Repository (University of Thessaly)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145722265","host_organization_name":"University of Thessaly","host_organization_lineage":["https://openalex.org/I145722265"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journalArticle"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1568167689","https://openalex.org/W1892519879","https://openalex.org/W1973278012","https://openalex.org/W1986826310","https://openalex.org/W1988371370","https://openalex.org/W1989907625","https://openalex.org/W1993065115","https://openalex.org/W1993616996","https://openalex.org/W1998667654","https://openalex.org/W2001675896","https://openalex.org/W2012088517","https://openalex.org/W2021634519","https://openalex.org/W2022067787","https://openalex.org/W2022460911","https://openalex.org/W2025875442","https://openalex.org/W2030100501","https://openalex.org/W2034885353","https://openalex.org/W2050291905","https://openalex.org/W2050718387","https://openalex.org/W2060952558","https://openalex.org/W2082317171","https://openalex.org/W2089154676","https://openalex.org/W2090504602","https://openalex.org/W2096183212","https://openalex.org/W2098348380","https://openalex.org/W2123012535","https://openalex.org/W2150437477","https://openalex.org/W2335823224","https://openalex.org/W2770334239","https://openalex.org/W4253297933"],"related_works":["https://openalex.org/W2979738679","https://openalex.org/W1211012066","https://openalex.org/W2091575641","https://openalex.org/W2012266888","https://openalex.org/W2088734821","https://openalex.org/W3194690039","https://openalex.org/W3093444445","https://openalex.org/W2270799151","https://openalex.org/W3127779199","https://openalex.org/W2373691527"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Recent":[1],"advances":[2],"in":[3,55,94,112,125,130,166,209,220,236,245],"regenerative":[4],"medicine,":[5],"including":[6],"hematopoietic":[7],"stem":[8],"cell":[9,126,137],"(HSC)":[10],"transplantation,":[11],"have":[12],"brought":[13],"hope":[14],"for":[15,70,106],"patients":[16,50,61,103,147,217,237],"with":[17,62,132,238],"severe":[18],"alcoholic":[19],"liver":[20,57],"cirrhosis":[21],"(ALC).":[22],"The":[23,179,205,240],"aim":[24],"of":[25,35,48,140,181,212],"this":[26],"study":[27,193,247],"was":[28,128],"to":[29,228],"assess":[30],"the":[31,45,52,56,78,88,99,113,149,192,246],"safety":[32],"and":[33,51,86,96,110,116,152,174,185,195,231,242,251],"efficacy":[34],"administering":[36],"autologous":[37,89,233],"expanded":[38,93],"mobilized":[39],"adult":[40],"progenitor":[41],"CD34+":[42,90,234],"cells":[43,91,235],"into":[44,77,98],"hepatic":[46,100],"artery":[47],"ALC":[49],"potential":[53],"improvement":[54,190,219,244],"function.":[58],"METHODS:":[59],"Nine":[60],"biopsy-proven":[63],"ALC,":[64],"who":[65],"had":[66,218],"abstained":[67],"from":[68],"alcohol":[69],"at":[71],"least":[72],"6":[73],"months,":[74],"were":[75,92,104,154,163,196],"recruited":[76],"study.":[79],"Following":[80],"granulocyte":[81],"colony-stimulating":[82],"factor":[83],"(G-CSF)":[84],"mobilization":[85],"leukapheresis,":[87],"vitro":[95],"injected":[97],"artery.":[101],"All":[102,146],"monitored":[105],"side":[107,157],"effects,":[108],"toxicities,":[109],"changes":[111],"clinical,":[114],"hematological,":[115],"biochemical":[117,243],"parameters.":[118],"RESULTS:":[119],"On":[120],"average,":[121],"a":[122,133],"five-fold":[123],"expansion":[124],"number":[127],"achieved":[129],"vitro,":[131],"mean":[134],"total":[135],"nucleated":[136],"count":[138],"(TNCC)":[139],"2.3":[141],"x":[142],"10(8)":[143],"pre":[144],"infusion.":[145,178,204],"tolerated":[148],"procedure":[150],"well,":[151],"there":[153],"no":[155],"treatment-related":[156],"effects":[158],"or":[159],"toxicities":[160],"observed.":[161],"There":[162],"significant":[164,197],"decreases":[165],"serum":[167],"bilirubin":[168],"(P":[169,198],"<":[170,199],"0.05)":[171,200],"4,":[172],"8,":[173],"12":[175],"wk":[176,202],"post":[177,203],"levels":[180],"alanine":[182],"transaminase":[183,187],"(ALT)":[184],"aspartate":[186],"(AST)":[188],"showed":[189],"through":[191],"period":[194],"1":[201],"Child-Pugh":[206],"score":[207],"improved":[208],"7":[210],"out":[211],"9":[213],"patients,":[214],"while":[215],"5":[216],"ascites":[221],"on":[222],"imaging.":[223],"CONCLUSION:":[224],"It":[225],"is":[226,249],"safe":[227],"mobilize,":[229],"expand,":[230],"reinfuse":[232],"ALC.":[239],"clinical":[241,254],"group":[248],"encouraging":[250],"warrants":[252],"further":[253],"trials.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":19},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":27},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":23}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}