{"id":"https://openalex.org/W1996569718","doi":"https://doi.org/10.1507/endocrj.k05-132","title":"Changes in Serum Sex Hormone Profiles after Short-term Low-dose Administration of Dehydroepiandrosterone (DHEA) to Young and Elderly Persons","display_name":"Changes in Serum Sex Hormone Profiles after Short-term Low-dose Administration of Dehydroepiandrosterone (DHEA) to Young and Elderly Persons","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1996569718","doi":"https://doi.org/10.1507/endocrj.k05-132","mag":"1996569718","pmid":"https://pubmed.ncbi.nlm.nih.gov/17185878"},"language":"en","primary_location":{"id":"doi:10.1507/endocrj.k05-132","doi":"https://doi.org/10.1507/endocrj.k05-132","is_oa":true,"landing_page_url":"https://doi.org/10.1507/endocrj.k05-132","pdf_url":"https://www.jstage.jst.go.jp/article/endocrj/54/1/54_1_153/_pdf","source":{"id":"https://openalex.org/S191387813","display_name":"Endocrine Journal","issn_l":"0918-8959","issn":["0918-8959","1348-4540"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313267","host_organization_name":"Japan Endocrine Society","host_organization_lineage":["https://openalex.org/P4310313267"],"host_organization_lineage_names":["Japan Endocrine Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrine Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/endocrj/54/1/54_1_153/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102398216","display_name":"Yoshihiko Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiko YAMADA","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077902770","display_name":"Hisahiko Sekihara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisahiko SEKIHARA","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021311208","display_name":"Masao Omura","orcid":"https://orcid.org/0000-0002-5149-531X","observed_orcids":["https://orcid.org/0000-0002-5149-531X"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao OMURA","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020123456","display_name":"Toshihiko Yanase","orcid":"https://orcid.org/0000-0003-2971-9943","observed_orcids":["https://orcid.org/0000-0003-2971-9943"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihiko YANASE","raw_affiliation_strings":["Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110010291","display_name":"Ryoichi Takayanagi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryoichi TAKAYANAGI","raw_affiliation_strings":["Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018784420","display_name":"Tomoatsu Mune","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoatsu MUNE","raw_affiliation_strings":["Department of Endocrinology, Diabetes, and Rheumatology, Gifu University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetes, and Rheumatology, Gifu University School of Medicine","institution_ids":["https://openalex.org/I42405503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108428709","display_name":"Keigo Yasuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keigo YASUDA","raw_affiliation_strings":["Department of Endocrinology, Diabetes, and Rheumatology, Gifu University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetes, and Rheumatology, Gifu University School of Medicine","institution_ids":["https://openalex.org/I42405503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034898325","display_name":"Tatsuo Ishizuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tatsuo ISHIZUKA","raw_affiliation_strings":["General Internal Medicine, Gifu University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Internal Medicine, Gifu University School of Medicine","institution_ids":["https://openalex.org/I42405503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038646840","display_name":"Hajime Ueshiba","orcid":"https://orcid.org/0000-0002-8090-352X","observed_orcids":["https://orcid.org/0000-0002-8090-352X"]},"institutions":[{"id":"https://openalex.org/I129634264","display_name":"Toho University","ror":"https://ror.org/02hcx7n63","country_code":"JP","type":"education","lineage":["https://openalex.org/I129634264"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hajime UESHIBA","raw_affiliation_strings":["First Department of Internal Medicine, Toho University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Toho University School of Medicine","institution_ids":["https://openalex.org/I129634264"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089062007","display_name":"Yukitaka Miyachi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129634264","display_name":"Toho University","ror":"https://ror.org/02hcx7n63","country_code":"JP","type":"education","lineage":["https://openalex.org/I129634264"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukitaka MIYACHI","raw_affiliation_strings":["First Department of Internal Medicine, Toho University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Toho University School of Medicine","institution_ids":["https://openalex.org/I129634264"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007488963","display_name":"Tomoyuki Iwasaki","orcid":"https://orcid.org/0000-0002-1000-2099","observed_orcids":["https://orcid.org/0000-0002-1000-2099"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoyuki IWASAKI","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Yokohama City University, Graduate School of Medicine","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002514925","display_name":"Atsushi Nakajima","orcid":"https://orcid.org/0000-0002-6263-1436","observed_orcids":["https://orcid.org/0000-0002-6263-1436"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi NAKAJIMA","raw_affiliation_strings":["Department of Gastroenterology, Yokohama City University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Yokohama City University Graduate School of Medicine","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113564437","display_name":"Hajime Nawata","orcid":"https://orcid.org/0009-0005-4166-9493","observed_orcids":["https://orcid.org/0009-0005-4166-9493"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hajime NAWATA","raw_affiliation_strings":["Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University","institution_ids":["https://openalex.org/I135598925"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9746,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.7836107,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"54","issue":"1","first_page":"153","last_page":"162"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dehydroepiandrosterone","display_name":"dehydroepiandrosterone","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dhea-sulfate","display_name":"DHEA sulfate","score":0.9409999847412109},{"id":"https://openalex.org/keywords/sex-hormone-replacement-therapy","display_name":"sex hormone replacement therapy","score":0.5870000123977661},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6200000047683716},{"id":"https://openalex.org/keywords/androstenedione","display_name":"androstenedione","score":0.8730000257492065},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9700000286102295},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.8339999914169312},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.828000009059906},{"id":"https://openalex.org/keywords/glucose-tolerance","display_name":"glucose tolerance","score":0.9300000071525574}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8258486986160278},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8253307342529297},{"id":"https://openalex.org/C2776992908","wikidata":"https://www.wikidata.org/wiki/Q408376","display_name":"Dehydroepiandrosterone","level":4,"score":0.7967292666435242},{"id":"https://openalex.org/C2780657110","wikidata":"https://www.wikidata.org/wiki/Q2505402","display_name":"Dehydroepiandrosterone sulfate","level":4,"score":0.7912085652351379},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7548043727874756},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4950486719608307},{"id":"https://openalex.org/C2776683971","wikidata":"https://www.wikidata.org/wiki/Q411064","display_name":"Androstenedione","level":4,"score":0.4617829918861389},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4516817331314087},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.4454444944858551},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.39630842208862305},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.25969600677490234},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003687","descriptor_name":"Dehydroepiandrosterone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D003687","descriptor_name":"Dehydroepiandrosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003687","descriptor_name":"Dehydroepiandrosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012739","descriptor_name":"Gonadal Steroid Hormones","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1507/endocrj.k05-132","doi":"https://doi.org/10.1507/endocrj.k05-132","is_oa":true,"landing_page_url":"https://doi.org/10.1507/endocrj.k05-132","pdf_url":"https://www.jstage.jst.go.jp/article/endocrj/54/1/54_1_153/_pdf","source":{"id":"https://openalex.org/S191387813","display_name":"Endocrine Journal","issn_l":"0918-8959","issn":["0918-8959","1348-4540"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313267","host_organization_name":"Japan Endocrine Society","host_organization_lineage":["https://openalex.org/P4310313267"],"host_organization_lineage_names":["Japan Endocrine Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrine Journal","raw_type":"journal-article"},{"id":"pmid:17185878","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17185878","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrine journal","raw_type":"Clinical Trial"}],"best_oa_location":{"id":"doi:10.1507/endocrj.k05-132","doi":"https://doi.org/10.1507/endocrj.k05-132","is_oa":true,"landing_page_url":"https://doi.org/10.1507/endocrj.k05-132","pdf_url":"https://www.jstage.jst.go.jp/article/endocrj/54/1/54_1_153/_pdf","source":{"id":"https://openalex.org/S191387813","display_name":"Endocrine Journal","issn_l":"0918-8959","issn":["0918-8959","1348-4540"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313267","host_organization_name":"Japan Endocrine Society","host_organization_lineage":["https://openalex.org/P4310313267"],"host_organization_lineage_names":["Japan Endocrine Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrine Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.7900000214576721,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306153","display_name":"Brain Research Foundation","ror":"https://ror.org/0492gsr48"},{"id":"https://openalex.org/F4320321945","display_name":"Ministry of Health, Labour and Welfare","ror":"https://ror.org/03mwa7s65"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1996569718.pdf","grobid_xml":"https://content.openalex.org/works/W1996569718.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W159198585","https://openalex.org/W1585897597","https://openalex.org/W1593442063","https://openalex.org/W1966758596","https://openalex.org/W1970025509","https://openalex.org/W1970784485","https://openalex.org/W1983659537","https://openalex.org/W1984770458","https://openalex.org/W1986568472","https://openalex.org/W1986657131","https://openalex.org/W1986810324","https://openalex.org/W1993272957","https://openalex.org/W1998106197","https://openalex.org/W2001530503","https://openalex.org/W2012190089","https://openalex.org/W2012980964","https://openalex.org/W2023315536","https://openalex.org/W2027318457","https://openalex.org/W2034450138","https://openalex.org/W2045402270","https://openalex.org/W2063030798","https://openalex.org/W2064310817","https://openalex.org/W2074680905","https://openalex.org/W2074933440","https://openalex.org/W2075506379","https://openalex.org/W2075532250","https://openalex.org/W2083183295","https://openalex.org/W2091187697","https://openalex.org/W2095427240","https://openalex.org/W2097863279","https://openalex.org/W2103240729","https://openalex.org/W2106286936","https://openalex.org/W2110124224","https://openalex.org/W2137990150","https://openalex.org/W2141677306","https://openalex.org/W2151530210","https://openalex.org/W2152180761","https://openalex.org/W2156116786","https://openalex.org/W2158015610","https://openalex.org/W2160234571","https://openalex.org/W2324268873","https://openalex.org/W4252566727"],"related_works":["https://openalex.org/W2172978234","https://openalex.org/W7111776708","https://openalex.org/W2126072473","https://openalex.org/W2130095506","https://openalex.org/W2137990150","https://openalex.org/W2082792497","https://openalex.org/W3162630821","https://openalex.org/W178868123","https://openalex.org/W1924799945","https://openalex.org/W2944329329"],"abstract_inverted_index":{"In":[0,45,153],"man,":[1],"serum":[2,163,181,186,208],"concentrations":[3,26,93],"of":[4,33,55,94,150,188,202,215,218,228],"dehydroepiandrosterone":[5],"(DHEA)":[6],"and":[7,24,52,97,102,109,116,129,137,165,184,193,212],"DHEA":[8,23,56,81,105,119,136,145,172,182,205],"sulfate":[9],"(DHEAS)":[10],"decrease":[11],"with":[12],"age":[13,43],"after":[14,103,117,143,170],"the":[15,20,31,41,50,87,104,118,144,171,180,185,207,216,219,223],"twenties.":[16],"For":[17],"this":[18,46],"reason,":[19],"decline":[21],"in":[22,40,86],"DHEAS":[25,138],"may":[27],"be":[28],"related":[29],"to":[30,58,222],"development":[32],"some":[34],"chronic":[35],"diseases":[36],"that":[37,227],"are":[38],"prevalent":[39],"older":[42,157,220],"population.":[44],"study,":[47],"we":[48],"evaluate":[49],"benefit":[51],"safety":[53],"level":[54,225],"administration":[57,120,146,201],"men":[59],"as":[60,226],"a":[61,83,122],"hormone":[62],"replacement":[63],"therapy.":[64],"Twenty-two":[65],"healthy":[66],"Japanese":[67],"males":[68],"(age":[69],"26-63;":[70],"mean":[71],"+/-":[72,75],"SD,":[73],"41.0":[74],"10.0":[76],"yrs.)":[77],"received":[78],"25":[79,203],"mg":[80,204],"once":[82],"day":[84],"orally":[85],"morning":[88],"for":[89,147,197],"two":[90],"weeks.":[91],"Serum":[92,135],"steroid":[95],"hormones":[96],"cytokines":[98],"were":[99,112,140,156,168,177],"measured":[100],"before":[101,115],"administration.":[106,173],"Glucose":[107],"tolerance":[108,127],"insulin":[110],"resistance":[111],"also":[113],"assessed":[114],"using":[121],"75":[123],"g":[124],"oral":[125],"glucose":[126],"test":[128,151],"homeostasis":[130],"model":[131],"assessment":[132],"(HOMA-R),":[133],"respectively.":[134],"levels":[139,167,214],"significantly":[141],"elevated":[142,169],"all":[148,198],"ages":[149],"subjects.":[152,199,230],"subjects":[154,217],"who":[155],"than":[158],"41":[159],"yrs.":[160],"(older":[161],"group)":[162],"androstenedione":[164],"estradiol":[166,213],"Significant":[174],"negative":[175],"correlations":[176],"observed":[178],"between":[179],"concentration":[183,187],"fasting":[189],"insulin,":[190],"HOMA-R,":[191],"leptin,":[192],"high-sensitivity":[194],"C-reactive":[195],"protein":[196],"Daily":[200],"increased":[206],"DHEA,":[209],"DHEAS,":[210],"androstenedione,":[211],"group":[221],"same":[224],"younger":[229]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}