{"id":"https://openalex.org/W1996544873","doi":"https://doi.org/10.1007/bf00915975","title":"Isotypes of surface immunoglobulin on B lymphocytes from patients with immune deficiency","display_name":"Isotypes of surface immunoglobulin on B lymphocytes from patients with immune deficiency","publication_year":1982,"publication_date":"1982-01-01","ids":{"openalex":"https://openalex.org/W1996544873","doi":"https://doi.org/10.1007/bf00915975","mag":"1996544873","pmid":"https://pubmed.ncbi.nlm.nih.gov/6980225"},"language":"en","primary_location":{"id":"doi:10.1007/bf00915975","doi":"https://doi.org/10.1007/bf00915975","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00915975","pdf_url":null,"source":{"id":"https://openalex.org/S57504206","display_name":"Journal of Clinical Immunology","issn_l":"0271-9142","issn":["0271-9142","1573-2592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026268117","display_name":"Jerrold F. Schwaber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerrold F. Schwaber","raw_affiliation_strings":["Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, 02115, Boston, Massachusetts","Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, 02115, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, Boston","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111433586","display_name":"Fred S. Rosen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fred S. Rosen","raw_affiliation_strings":["Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, 02115, Boston, Massachusetts","Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, 02115, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Immunology Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, Boston","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":0.5478,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.63234529,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"1","first_page":"30","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12919","display_name":"Blood disorders and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/b-cell-subsets","display_name":"B cell subsets","score":0.9100000262260437},{"id":"https://openalex.org/keywords/agammaglobulinemia","display_name":"agammaglobulinemia","score":0.984000027179718},{"id":"https://openalex.org/keywords/hyper-igm-syndrome","display_name":"hyper-IgM syndrome","score":0.7559999823570251},{"id":"https://openalex.org/keywords/immunoglobulin-deficiency","display_name":"antibody deficiency","score":0.7020000219345093},{"id":"https://openalex.org/keywords/peripheral-blood-b-cells","display_name":"peripheral blood B cells","score":0.640999972820282}],"concepts":[{"id":"https://openalex.org/C48010095","wikidata":"https://www.wikidata.org/wiki/Q79447","display_name":"Immunoglobulin D","level":4,"score":0.8194675445556641},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.722330629825592},{"id":"https://openalex.org/C2777991845","wikidata":"https://www.wikidata.org/wiki/Q2396793","display_name":"Isotype","level":4,"score":0.7082597017288208},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6231858730316162},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5965855717658997},{"id":"https://openalex.org/C2776433325","wikidata":"https://www.wikidata.org/wiki/Q1472818","display_name":"Common variable immunodeficiency","level":3,"score":0.574573814868927},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.5199466943740845},{"id":"https://openalex.org/C2777607303","wikidata":"https://www.wikidata.org/wiki/Q641307","display_name":"Immunodeficiency","level":3,"score":0.4902673065662384},{"id":"https://openalex.org/C145558887","wikidata":"https://www.wikidata.org/wiki/Q3832893","display_name":"B-1 cell","level":5,"score":0.4759923219680786},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4655863344669342},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.4326326251029968},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.3384861350059509},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.13421520590782166},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.0629446804523468}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000361","descriptor_name":"Agammaglobulinemia","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D000361","descriptor_name":"Agammaglobulinemia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004406","descriptor_name":"Dysgammaglobulinemia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007072","descriptor_name":"Immunoglobulin D","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011947","descriptor_name":"Receptors, Antigen, B-Cell","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00915975","doi":"https://doi.org/10.1007/bf00915975","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00915975","pdf_url":null,"source":{"id":"https://openalex.org/S57504206","display_name":"Journal of Clinical Immunology","issn_l":"0271-9142","issn":["0271-9142","1573-2592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:6980225","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6980225","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306728","display_name":"Charles H. Hood Foundation","ror":"https://ror.org/01ctnwa22"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1449657241","https://openalex.org/W1572008288","https://openalex.org/W1587155866","https://openalex.org/W1774761485","https://openalex.org/W1923398670","https://openalex.org/W1963984598","https://openalex.org/W1979055029","https://openalex.org/W1989224230","https://openalex.org/W1990416147","https://openalex.org/W1998940604","https://openalex.org/W2000843974","https://openalex.org/W2016945063","https://openalex.org/W2021923341","https://openalex.org/W2071545545","https://openalex.org/W2075338554","https://openalex.org/W2075964214","https://openalex.org/W2093825456","https://openalex.org/W2097793838","https://openalex.org/W2124575653","https://openalex.org/W2137228289","https://openalex.org/W2145386768","https://openalex.org/W2167119483","https://openalex.org/W2329835228","https://openalex.org/W2336449268","https://openalex.org/W2414112311","https://openalex.org/W2418246362","https://openalex.org/W2612023855","https://openalex.org/W4237874187"],"related_works":["https://openalex.org/W170328879","https://openalex.org/W2168529125","https://openalex.org/W2024139507","https://openalex.org/W7100358392","https://openalex.org/W2069177404","https://openalex.org/W2015897818","https://openalex.org/W1635215098","https://openalex.org/W2083927850","https://openalex.org/W2145386768","https://openalex.org/W2088476630"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}