{"id":"https://openalex.org/W1996509769","doi":"https://doi.org/10.1007/s00125-009-1400-1","title":"Phenotype\u2013genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling","display_name":"Phenotype\u2013genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling","publication_year":2009,"publication_date":"2009-05-28","ids":{"openalex":"https://openalex.org/W1996509769","doi":"https://doi.org/10.1007/s00125-009-1400-1","mag":"1996509769","pmid":"https://pubmed.ncbi.nlm.nih.gov/19479237"},"language":"en","primary_location":{"id":"doi:10.1007/s00125-009-1400-1","doi":"https://doi.org/10.1007/s00125-009-1400-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-009-1400-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-009-1400-1.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/s00125-009-1400-1.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056116087","display_name":"Xinyuan Song","orcid":"https://orcid.org/0000-0002-6446-3667","observed_orcids":["https://orcid.org/0000-0002-6446-3667"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"X. Y. Song","raw_affiliation_strings":["Department of Statistics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China","Department of Statistics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Statistics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018144787","display_name":"S. Y. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"S. Y. Lee","raw_affiliation_strings":["Department of Statistics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Statistics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Statistics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R. C. W. Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"R. C. W. Ma","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103963544","display_name":"Wing\u2010Yee So","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"W. Y. So","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020405716","display_name":"Jingheng Cai","orcid":"https://orcid.org/0000-0001-8267-3361","observed_orcids":["https://orcid.org/0000-0001-8267-3361"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"J. H. Cai","raw_affiliation_strings":["Department of Statistics, School of Mathematics and Computational Science, Sun Yat-sen University, Guangzhou, People\u2019s Republic of China","Department of Statistics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Statistics, The Chinese University of Hong Kong, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, School of Mathematics and Computational Science, Sun Yat-sen University, Guangzhou, People\u2019s Republic of China","institution_ids":["https://openalex.org/I157773358"]},{"raw_affiliation_string":"Department of Statistics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Statistics, The Chinese University of Hong Kong, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009105983","display_name":"Claudia H.T. Tam","orcid":"https://orcid.org/0000-0002-9169-0013","observed_orcids":["https://orcid.org/0000-0002-9169-0013"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"C. Tam","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108412325","display_name":"Vincent Lam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"V. Lam","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":null,"display_name":"W. Ying","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"W. Ying","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034303175","display_name":"Maggie C.Y. Ng","orcid":"https://orcid.org/0000-0002-4133-2007","observed_orcids":["https://orcid.org/0000-0002-4133-2007"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"M. C. Y. Ng","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091832416","display_name":"Juliana C.N. Chan","orcid":"https://orcid.org/0000-0003-1325-1194","observed_orcids":["https://orcid.org/0000-0003-1325-1194"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":true,"raw_author_name":"J. C. N. Chan","raw_affiliation_strings":["Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, People\u2019s Republic of China","Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 32 Ngan Shing Street, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People\u2019s Republic of China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5091832416"],"corresponding_institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"],"apc_list":{"value":3490,"currency":"USD","value_usd":3490},"apc_paid":null,"fwci":1.7193,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.84799096,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"52","issue":"8","first_page":"1543","last_page":"1553"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9829999804496765},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.9639999866485596},{"id":"https://openalex.org/keywords/urinary-albumin-creatinine-ratio","display_name":"urinary albumin-creatinine ratio","score":0.8799999952316284},{"id":"https://openalex.org/keywords/serum-creatinine","display_name":"serum creatinine","score":0.8259999752044678},{"id":"https://openalex.org/keywords/endothelial-nitric-oxide-synthase","display_name":"endothelial nitric oxide synthase","score":0.8930000066757202},{"id":"https://openalex.org/keywords/beta-adrenergic-receptors","display_name":"beta-adrenergic receptors","score":0.9729999899864197},{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.9929999709129333},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6480000019073486},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.7509999871253967},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.8569999933242798},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.7269999980926514},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6083014011383057},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.6008049249649048},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.59935462474823},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.5596738457679749},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.48264533281326294},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.4139740467071533},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3954613208770752},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38118019700050354},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29389071464538574},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21352961659431458},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18115398287773132}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D007677","descriptor_name":"Kidney Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00125-009-1400-1","doi":"https://doi.org/10.1007/s00125-009-1400-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-009-1400-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-009-1400-1.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},{"id":"pmid:19479237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19479237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s00125-009-1400-1","doi":"https://doi.org/10.1007/s00125-009-1400-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-009-1400-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-009-1400-1.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322942","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1996509769.pdf","grobid_xml":"https://content.openalex.org/works/W1996509769.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W82809700","https://openalex.org/W287150709","https://openalex.org/W1525845993","https://openalex.org/W1526927233","https://openalex.org/W1541471661","https://openalex.org/W1816720378","https://openalex.org/W1964139747","https://openalex.org/W1964607854","https://openalex.org/W1971213885","https://openalex.org/W1992283514","https://openalex.org/W1992404999","https://openalex.org/W1999200175","https://openalex.org/W2003670762","https://openalex.org/W2009554185","https://openalex.org/W2016222005","https://openalex.org/W2030411777","https://openalex.org/W2035237584","https://openalex.org/W2046335747","https://openalex.org/W2049397775","https://openalex.org/W2056267318","https://openalex.org/W2059346848","https://openalex.org/W2069461486","https://openalex.org/W2073171519","https://openalex.org/W2075259797","https://openalex.org/W2080390592","https://openalex.org/W2083911580","https://openalex.org/W2086816425","https://openalex.org/W2090372047","https://openalex.org/W2096570124","https://openalex.org/W2105487207","https://openalex.org/W2112552231","https://openalex.org/W2113130878","https://openalex.org/W2122450058","https://openalex.org/W2123327565","https://openalex.org/W2130466611","https://openalex.org/W2138526092","https://openalex.org/W2140045396","https://openalex.org/W2145732657","https://openalex.org/W2145989568","https://openalex.org/W2147562946","https://openalex.org/W2151448177","https://openalex.org/W2161840616","https://openalex.org/W2165139442","https://openalex.org/W2166698530","https://openalex.org/W2168934042","https://openalex.org/W2170625932","https://openalex.org/W2171294019","https://openalex.org/W2270629577","https://openalex.org/W2322463216","https://openalex.org/W2335861081","https://openalex.org/W2490762048","https://openalex.org/W2973627903","https://openalex.org/W3021250193","https://openalex.org/W4211177544","https://openalex.org/W4238719302"],"related_works":["https://openalex.org/W3119005957","https://openalex.org/W2809563337","https://openalex.org/W2888039051","https://openalex.org/W4213435730","https://openalex.org/W2149148526","https://openalex.org/W2904870824","https://openalex.org/W2048597897","https://openalex.org/W7125675347","https://openalex.org/W4409781830","https://openalex.org/W3030428161"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}