{"id":"https://openalex.org/W1996406284","doi":"https://doi.org/10.1159/000130377","title":"Characterization and chromosomal localization of DNA in condensed and dispersed human chromatin","display_name":"Characterization and chromosomal localization of DNA in condensed and dispersed human chromatin","publication_year":2008,"publication_date":"2008-05-06","ids":{"openalex":"https://openalex.org/W1996406284","doi":"https://doi.org/10.1159/000130377","mag":"1996406284","pmid":"https://pubmed.ncbi.nlm.nih.gov/1192811"},"language":"en","primary_location":{"id":"doi:10.1159/000130377","doi":"https://doi.org/10.1159/000130377","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000130377","pdf_url":null,"source":{"id":"https://openalex.org/S4210179014","display_name":"Cytogenetics and Cell Genetics","issn_l":"0301-0171","issn":["0301-0171","1421-9816"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytogenetics and Cell Genetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114248008","display_name":"John R. Gosden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800150677","display_name":"Western General Hospital","ror":"https://ror.org/009kr6r15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324252669","https://openalex.org/I2800150677"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J.R. Gosden","raw_affiliation_strings":["MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh","institution_ids":["https://openalex.org/I2800150677"]}]},{"author_position":"middle","author":{"id":null,"display_name":"A.R. Mitchell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800150677","display_name":"Western General Hospital","ror":"https://ror.org/009kr6r15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324252669","https://openalex.org/I2800150677"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A.R. Mitchell","raw_affiliation_strings":["MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh","institution_ids":["https://openalex.org/I2800150677"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056445701","display_name":"Richard A. Buckland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800150677","display_name":"Western General Hospital","ror":"https://ror.org/009kr6r15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324252669","https://openalex.org/I2800150677"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R.A. Buckland","raw_affiliation_strings":["MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh","institution_ids":["https://openalex.org/I2800150677"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044724712","display_name":"R.P. Clayton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800150677","display_name":"Western General Hospital","ror":"https://ror.org/009kr6r15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324252669","https://openalex.org/I2800150677"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R.P. Clayton","raw_affiliation_strings":["MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh","institution_ids":["https://openalex.org/I2800150677"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087951880","display_name":"H.J. Evans","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H.J. Evans","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"3","first_page":"340","last_page":"341"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromatin-condensation","display_name":"chromatin condensation","score":0.7110000252723694},{"id":"https://openalex.org/keywords/human-chromosomes","display_name":"human chromosomes","score":0.4970000088214874},{"id":"https://openalex.org/keywords/chromosome-localization","display_name":"chromosomal localization","score":0.7870000004768372},{"id":"https://openalex.org/keywords/dna-characterization","display_name":"DNA characterization","score":0.5680000185966492},{"id":"https://openalex.org/keywords/condensed-chromatin","display_name":"condensed chromatin","score":0.7149999737739563},{"id":"https://openalex.org/keywords/chromosome-structure","display_name":"chromosome structure","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.828364372253418},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7797951102256775},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6823633313179016},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4830389618873596},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.4791243076324463},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.452776700258255},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.44827035069465637},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3214242458343506},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3208279609680176},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.17443609237670898},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.12628662586212158}],"mesh":[{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006824","descriptor_name":"Hybridization, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1159/000130377","doi":"https://doi.org/10.1159/000130377","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000130377","pdf_url":null,"source":{"id":"https://openalex.org/S4210179014","display_name":"Cytogenetics and Cell Genetics","issn_l":"0301-0171","issn":["0301-0171","1421-9816"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytogenetics and Cell Genetics","raw_type":"journal-article"},{"id":"pmid:1192811","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1192811","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytogenetics and cell genetics","raw_type":"Journal Article"},{"id":"pmid:1203475","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1203475","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Birth defects original article series","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2398040428","https://openalex.org/W2481753232","https://openalex.org/W1537522868","https://openalex.org/W3202599723","https://openalex.org/W2057129188","https://openalex.org/W3026251315","https://openalex.org/W2528543044","https://openalex.org/W4300371788","https://openalex.org/W3015262743","https://openalex.org/W2756740232"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}