{"id":"https://openalex.org/W1996349976","doi":"https://doi.org/10.1007/bf00195763","title":"Differentiation of the mammalian retinal pigment epithelium in vitro: Influence of presumptive retinal neuroepithelium and head mesenchyme","display_name":"Differentiation of the mammalian retinal pigment epithelium in vitro: Influence of presumptive retinal neuroepithelium and head mesenchyme","publication_year":1993,"publication_date":"1993-03-01","ids":{"openalex":"https://openalex.org/W1996349976","doi":"https://doi.org/10.1007/bf00195763","mag":"1996349976","pmid":"https://pubmed.ncbi.nlm.nih.gov/8470826"},"language":"en","primary_location":{"id":"doi:10.1007/bf00195763","doi":"https://doi.org/10.1007/bf00195763","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00195763","pdf_url":null,"source":{"id":"https://openalex.org/S522974","display_name":"Anatomy and Embryology","issn_l":"0340-2061","issn":["0340-2061","1432-0568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anatomy and Embryology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111790589","display_name":"Eberhard Buse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Eberhard Buse","raw_affiliation_strings":["Anatomisches Institut, Universit\u00e4t Kiel, Germany","Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anatomisches Institut, Universit\u00e4t Kiel, Germany","institution_ids":["https://openalex.org/I32021983"]},{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Thomas Eichmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Eichmann","raw_affiliation_strings":["Anatomisches Institut der Universit\u00e4t Kiel, Olshausenstrasse 40, W-2300, Kiel, 1, Germany","Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Olshausenstrasse 40, W-2300, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]},{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Heink deGroot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Heink deGroot","raw_affiliation_strings":["Anatomisches Institut der Universit\u00e4t Kiel, Olshausenstrasse 40, W-2300, Kiel, 1, Germany","Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Olshausenstrasse 40, W-2300, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]},{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081570599","display_name":"Anja Leker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anja Leker","raw_affiliation_strings":["Anatomisches Institut der Universit\u00e4t Kiel, Olshausenstrasse 40, W-2300, Kiel, 1, Germany","Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Olshausenstrasse 40, W-2300, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]},{"raw_affiliation_string":"Anatomisches Institut der Universit\u00e4t Kiel, Kiel, 1, Germany","institution_ids":["https://openalex.org/I32021983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I32021983"],"apc_list":null,"apc_paid":null,"fwci":1.2706,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.78660938,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"187","issue":"3","first_page":"259","last_page":"68"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.8535000085830688,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.8535000085830688,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.1103999987244606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12989","display_name":"Ocular Disorders and Treatments","score":0.022199999541044235,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-pigment-epithelium-differentiation","display_name":"retinal pigment epithelium differentiation","score":0.9290000200271606},{"id":"https://openalex.org/keywords/neural-crest","display_name":"neural crest","score":0.3199999928474426},{"id":"https://openalex.org/keywords/eye-primordium","display_name":"eye primordium","score":0.621999979019165},{"id":"https://openalex.org/keywords/eye-cup","display_name":"eye cup","score":0.5180000066757202},{"id":"https://openalex.org/keywords/neuroretina","display_name":"neuroretina","score":0.6850000023841858},{"id":"https://openalex.org/keywords/head-mesenchyme","display_name":"head mesenchyme","score":0.7889999747276306},{"id":"https://openalex.org/keywords/heterotopic-transplantation","display_name":"heterotopic transplantation","score":0.7080000042915344},{"id":"https://openalex.org/keywords/mouse-embryo","display_name":"mouse embryo","score":0.5099999904632568},{"id":"https://openalex.org/keywords/neural-plate","display_name":"neural plate","score":0.3140000104904175},{"id":"https://openalex.org/keywords/optic-stalk","display_name":"optic stalk","score":0.6639999747276306},{"id":"https://openalex.org/keywords/glial-lineage","display_name":"glial lineage","score":0.4350000023841858}],"concepts":[{"id":"https://openalex.org/C200707615","wikidata":"https://www.wikidata.org/wiki/Q13652744","display_name":"Neuroepithelial cell","level":4,"score":0.9289373159408569},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7600772380828857},{"id":"https://openalex.org/C102225024","wikidata":"https://www.wikidata.org/wiki/Q1388375","display_name":"Neurulation","level":5,"score":0.6880201101303101},{"id":"https://openalex.org/C184750944","wikidata":"https://www.wikidata.org/wiki/Q557677","display_name":"Primordium","level":3,"score":0.6487438678741455},{"id":"https://openalex.org/C2780594696","wikidata":"https://www.wikidata.org/wiki/Q1127402","display_name":"Neural tube","level":3,"score":0.6399288177490234},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6009398698806763},{"id":"https://openalex.org/C96021297","wikidata":"https://www.wikidata.org/wiki/Q7098791","display_name":"Optic cup (embryology)","level":5,"score":0.5404821634292603},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.5403817296028137},{"id":"https://openalex.org/C197849852","wikidata":"https://www.wikidata.org/wiki/Q2314823","display_name":"Neural plate","level":4,"score":0.5320815443992615},{"id":"https://openalex.org/C2778024200","wikidata":"https://www.wikidata.org/wiki/Q2346242","display_name":"Retinal pigment epithelium","level":3,"score":0.5313164591789246},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5286667346954346},{"id":"https://openalex.org/C2776340970","wikidata":"https://www.wikidata.org/wiki/Q32838","display_name":"Mesenchyme","level":3,"score":0.49306437373161316},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.450785756111145},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.4188891351222992},{"id":"https://openalex.org/C114696181","wikidata":"https://www.wikidata.org/wiki/Q5422650","display_name":"Eye development","level":4,"score":0.3975096344947815},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.2723797559738159},{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.18657338619232178},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.17914807796478271},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1596207320690155},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11304643750190735},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.06333589553833008},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C129536746","wikidata":"https://www.wikidata.org/wiki/Q1141026","display_name":"Gastrulation","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D005314","descriptor_name":"Embryonic and Fetal Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008648","descriptor_name":"Mesoderm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010857","descriptor_name":"Pigment Epithelium of Eye","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D014183","descriptor_name":"Transplantation, Heterologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016332","descriptor_name":"Fetal Tissue Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00195763","doi":"https://doi.org/10.1007/bf00195763","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00195763","pdf_url":null,"source":{"id":"https://openalex.org/S522974","display_name":"Anatomy and Embryology","issn_l":"0340-2061","issn":["0340-2061","1432-0568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anatomy and Embryology","raw_type":"journal-article"},{"id":"pmid:8470826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8470826","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anatomy and embryology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W69789317","https://openalex.org/W142132412","https://openalex.org/W953211399","https://openalex.org/W985799322","https://openalex.org/W1510902265","https://openalex.org/W1526118431","https://openalex.org/W1971812181","https://openalex.org/W1973085782","https://openalex.org/W1981646860","https://openalex.org/W1989557131","https://openalex.org/W2006719211","https://openalex.org/W2007554464","https://openalex.org/W2008320280","https://openalex.org/W2013371970","https://openalex.org/W2021836407","https://openalex.org/W2023380771","https://openalex.org/W2032188919","https://openalex.org/W2045385068","https://openalex.org/W2046556165","https://openalex.org/W2050539735","https://openalex.org/W2051692850","https://openalex.org/W2060334880","https://openalex.org/W2064036773","https://openalex.org/W2070641078","https://openalex.org/W2075562216","https://openalex.org/W2091966430","https://openalex.org/W2120648798","https://openalex.org/W2126198257","https://openalex.org/W2332974635","https://openalex.org/W2476747534","https://openalex.org/W2491859759"],"related_works":["https://openalex.org/W2032188919","https://openalex.org/W2050991107","https://openalex.org/W2121740884","https://openalex.org/W2993306524","https://openalex.org/W7097113328","https://openalex.org/W2060816510","https://openalex.org/W4401529411","https://openalex.org/W2023920513","https://openalex.org/W2046373631","https://openalex.org/W4298304995"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}