{"id":"https://openalex.org/W1996326128","doi":"https://doi.org/10.1253/circj.70.810","title":"Gender Difference in Coronary Events in Relation to Risk Factors in Japanese Hypercholesterolemic Patients Treated With Low-Dose Simvastatin","display_name":"Gender Difference in Coronary Events in Relation to Risk Factors in Japanese Hypercholesterolemic Patients Treated With Low-Dose Simvastatin","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1996326128","doi":"https://doi.org/10.1253/circj.70.810","mag":"1996326128","pmid":"https://pubmed.ncbi.nlm.nih.gov/16799230"},"language":"en","primary_location":{"id":"doi:10.1253/circj.70.810","doi":"https://doi.org/10.1253/circj.70.810","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.70.810","pdf_url":"https://www.jstage.jst.go.jp/article/circj/70/7/70_7_810/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/circj/70/7/70_7_810/_pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089292835","display_name":"Junichi Sasaki","orcid":"https://orcid.org/0000-0002-5190-8524","observed_orcids":["https://orcid.org/0000-0002-5190-8524"]},"institutions":[{"id":"https://openalex.org/I79072001","display_name":"International University of Health and Welfare","ror":"https://ror.org/053d3tv41","country_code":"JP","type":"education","lineage":["https://openalex.org/I79072001"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jun Sasaki","raw_affiliation_strings":["International University of Health and Welfare Graduate School of Clinical Trial Management"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International University of Health and Welfare Graduate School of Clinical Trial Management","institution_ids":["https://openalex.org/I79072001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109115866","display_name":"Toru Kita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Kita","raw_affiliation_strings":["Kyoto University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University Graduate School of Medicine","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105358629","display_name":"Hiroshi Mabuchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Mabuchi","raw_affiliation_strings":["Kanazawa University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kanazawa University Graduate School of Medicine","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105788500","display_name":"Masunori Matsuzaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masunori Matsuzaki","raw_affiliation_strings":["Yamaguchi University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi University Graduate School of Medicine","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109934217","display_name":"Y\u016bji Matsuzawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117281","display_name":"Sumitomo Hospital","ror":"https://ror.org/02m9ewz37","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210117281"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuji Matsuzawa","raw_affiliation_strings":["Sumitomo Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sumitomo Hospital","institution_ids":["https://openalex.org/I4210117281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029039827","display_name":"Noriaki Nakaya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Noriaki Nakaya","raw_affiliation_strings":["Nakaya Clinic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nakaya Clinic","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002373909","display_name":"Shinichi Oikawa","orcid":"https://orcid.org/0000-0003-2160-3807","observed_orcids":["https://orcid.org/0000-0003-2160-3807"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Oikawa","raw_affiliation_strings":["Nippon Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nippon Medical School","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103484910","display_name":"Yasushi Sait\u014d","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Saito","raw_affiliation_strings":["Chiba University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chiba University Graduate School of Medicine","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055196139","display_name":"Kazuaki Shimamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuaki Shimamoto","raw_affiliation_strings":["Sapporo Medical University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sapporo Medical University School of Medicine","institution_ids":["https://openalex.org/I141882310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086790542","display_name":"Suminori Kono","orcid":"https://orcid.org/0000-0001-8516-4386","observed_orcids":["https://orcid.org/0000-0001-8516-4386"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Suminori Kono","raw_affiliation_strings":["Kyushu University Faculty of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyushu University Faculty of Medical Sciences","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054555090","display_name":"Hiroshige Itakura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33214746","display_name":"Ibaraki Christian University","ror":"https://ror.org/00r6nzx24","country_code":"JP","type":"education","lineage":["https://openalex.org/I33214746"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshige Itakura","raw_affiliation_strings":["Ibaraki Christian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ibaraki Christian University","institution_ids":["https://openalex.org/I33214746"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034018786","display_name":"the J-LIT Study Group","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"The J-LIT Study Group","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4911,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.89554485,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"70","issue":"7","first_page":"810","last_page":"814"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13252","display_name":"Sex and Gender in Healthcare","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7480000257492065},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9480000138282776},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.859000027179718},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":1.0},{"id":"https://openalex.org/keywords/simvastatin","display_name":"simvastatin","score":0.9120000004768372},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.8999999761581421},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9210000038146973},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9649999737739563},{"id":"https://openalex.org/keywords/coronary-risk-factors","display_name":"coronary risk factors","score":0.7170000076293945},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8886915445327759},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7309874892234802},{"id":"https://openalex.org/C2776329913","wikidata":"https://www.wikidata.org/wiki/Q670131","display_name":"Simvastatin","level":2,"score":0.71934974193573},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.643236517906189},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.5772531032562256},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5719277262687683},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5574891567230225},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5499460697174072},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.4682895541191101},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.42875537276268005},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2794884741306305},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.09989678859710693},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000924","descriptor_name":"Anticholesteremic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003643","descriptor_name":"Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019821","descriptor_name":"Simvastatin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1253/circj.70.810","doi":"https://doi.org/10.1253/circj.70.810","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.70.810","pdf_url":"https://www.jstage.jst.go.jp/article/circj/70/7/70_7_810/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},{"id":"pmid:16799230","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16799230","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation journal : official journal of the Japanese Circulation Society","raw_type":"Clinical Trial"},{"id":"pmh:oai:irdb.nii.ac.jp:01288:0000257549","doi":null,"is_oa":true,"landing_page_url":"https://kanazawa-u.repo.nii.ac.jp/records/13195","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Circulation Journal","raw_type":"journal article"},{"id":"pmh:oai:kanazawa-u.repo.nii.ac.jp:00013195","doi":null,"is_oa":true,"landing_page_url":"https://kanazawa-u.repo.nii.ac.jp/?action=repository_uri&item_id=13195","pdf_url":null,"source":{"id":"https://openalex.org/S4306400882","display_name":"Kanazawa University Repository for Academic Resources (DSpace) (Kanazawa University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I10091056","host_organization_name":"Kanazawa University","host_organization_lineage":["https://openalex.org/I10091056"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1253/circj.70.810","doi":"https://doi.org/10.1253/circj.70.810","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.70.810","pdf_url":"https://www.jstage.jst.go.jp/article/circj/70/7/70_7_810/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1996326128.pdf","grobid_xml":"https://content.openalex.org/works/W1996326128.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1510232599","https://openalex.org/W1530883209","https://openalex.org/W1551410027","https://openalex.org/W1973629357","https://openalex.org/W1987992772","https://openalex.org/W1992229080","https://openalex.org/W1992957574","https://openalex.org/W1995779077","https://openalex.org/W2004878568","https://openalex.org/W2058489152","https://openalex.org/W2083262340","https://openalex.org/W2083352049","https://openalex.org/W2091690694","https://openalex.org/W2106665921","https://openalex.org/W2116404316","https://openalex.org/W2136213395","https://openalex.org/W2143585811","https://openalex.org/W2144437066","https://openalex.org/W2155121555","https://openalex.org/W2316375493","https://openalex.org/W2335592377"],"related_works":["https://openalex.org/W4238947039","https://openalex.org/W2004878568","https://openalex.org/W2144437066","https://openalex.org/W2107154102","https://openalex.org/W1979124018","https://openalex.org/W2020030113","https://openalex.org/W2175798171","https://openalex.org/W7223391949","https://openalex.org/W2043180355","https://openalex.org/W2141929122"],"abstract_inverted_index":{"BACKGROUND:":[0],"Gender":[1],"differences":[2],"between":[3],"the":[4,17,147,185,204],"risk":[5,37,90,128,148,155,161,180,198,206],"factors":[6],"for":[7,36,152,158],"coronary":[8,12,39,76,92,150,167,182,208],"heart":[9],"disease":[10],"and":[11,31,44,60,70,99,110,116],"events":[13,40,77,93,151,168,183,209],"were":[14,34],"examined":[15],"in":[16,57,67,80,85,97,101,114,118,133,137,171,188,200],"Japan":[18],"Lipid":[19],"Intervention":[20],"Trial,":[21],"a":[22,195],"6-year":[23],"observational":[24],"study.":[25],"METHODS":[26],"AND":[27],"RESULTS:":[28],"Men":[29],"(12,575)":[30],"women":[32,71,81,102,119,153],"(27,013)":[33],"analyzed":[35],"of":[38,75,91,108,125,149,166,181,207],"(acute":[41],"myocardial":[42],"infarction":[43],"sudden":[45],"cardiac":[46],"death).":[47],"Simvastatin":[48],"reduced":[49],"serum":[50,62],"low-density":[51],"lipoprotein":[52,64],"cholesterol":[53,65],"(LDL-C)":[54],"by":[55,95,112],"27%":[56],"both":[58,189],"genders,":[59],"increased":[61,94,129,179],"high-density":[63],"(HDL-C)":[66],"men":[68,86,98,115,159],"(5%)":[69],"(4%).":[72],"The":[73,89,127,164],"incidence":[74,165],"was":[78,142],"lower":[79,170,205],"(0.64/1,000":[82],"patient-years)":[83],"than":[84,157],"(1.57/1,000":[87],"patient-years).":[88],"18%":[96],"21%":[100],"with":[103,120,131],"each":[104,121],"10":[105,122],"mg/dl":[106,123],"elevation":[107,124],"LDL-C,":[109],"decreased":[111],"39%":[113],"33%":[117],"HDL-C.":[126],"proportionally":[130],"aging":[132],"women,":[134,201],"but":[135],"not":[136],"men.":[138],"Diabetes":[139],"mellitus":[140],"(DM)":[141],"more":[143,196],"strongly":[144],"related":[145,176],"to":[146,177,184,193],"(relative":[154,160],"3.07)":[156],"1.58).":[162],"CONCLUSIONS:":[163],"is":[169,175],"women.":[172],"Serum":[173],"LDL-C":[174],"an":[178],"same":[186],"extent":[187],"genders.":[190],"DM":[191],"seems":[192],"be":[194],"important":[197],"factor":[199],"trading":[202],"off":[203],"among":[210],"them.":[211]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}