{"id":"https://openalex.org/W1996138707","doi":"https://doi.org/10.1021/bi010661o","title":"Differential Activity and Structure of Highly Similar Peroxidases. Spectroscopic, Crystallographic, and Enzymatic Analyses of Lignifying Arabidopsis thaliana Peroxidase A2 and Horseradish Peroxidase A2,","display_name":"Differential Activity and Structure of Highly Similar Peroxidases. Spectroscopic, Crystallographic, and Enzymatic Analyses of Lignifying Arabidopsis thaliana Peroxidase A2 and Horseradish Peroxidase A2,","publication_year":2001,"publication_date":"2001-08-18","ids":{"openalex":"https://openalex.org/W1996138707","doi":"https://doi.org/10.1021/bi010661o","mag":"1996138707","pmid":"https://pubmed.ncbi.nlm.nih.gov/11551197"},"language":"en","primary_location":{"id":"doi:10.1021/bi010661o","doi":"https://doi.org/10.1021/bi010661o","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi010661o","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056707731","display_name":"K\u00e5re Lehmann Nielsen","orcid":"https://orcid.org/0000-0002-5598-4401","observed_orcids":["https://orcid.org/0000-0002-5598-4401"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"K\u00e5re Lehmann Nielsen","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105416145","display_name":"Chiara Indiani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"Chiara Indiani","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036464361","display_name":"Anette Henriksen","orcid":"https://orcid.org/0000-0003-4051-5079","observed_orcids":["https://orcid.org/0000-0003-4051-5079"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"Anette Henriksen","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051599394","display_name":"Alessandro Feis","orcid":"https://orcid.org/0000-0003-3469-0647","observed_orcids":["https://orcid.org/0000-0003-3469-0647"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"Alessandro Feis","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059568777","display_name":"Maurizio Becucci","orcid":"https://orcid.org/0000-0002-2428-471X","observed_orcids":["https://orcid.org/0000-0002-2428-471X"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"Maurizio Becucci","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000797815","display_name":"Michael Gajhede","orcid":"https://orcid.org/0000-0001-9864-2287","observed_orcids":["https://orcid.org/0000-0001-9864-2287"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"Michael Gajhede","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014389744","display_name":"Giulietta Smulevich","orcid":"https://orcid.org/0000-0003-3021-8919","observed_orcids":["https://orcid.org/0000-0003-3021-8919"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":false,"raw_author_name":"Giulietta Smulevich","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036518743","display_name":"Karen Gjesing Welinder","orcid":"https://orcid.org/0000-0002-5409-0131","observed_orcids":["https://orcid.org/0000-0002-5409-0131"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1314107994","display_name":"European Laboratory for Non-Linear Spectroscopy","ror":"https://ror.org/04x48z588","country_code":"IT","type":"facility","lineage":["https://openalex.org/I1314107994","https://openalex.org/I45084792"]},{"id":"https://openalex.org/I2800060819","display_name":"Carlsberg Laboratory","ror":"https://ror.org/055hfb865","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2800060819"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK","IT"],"is_corresponding":true,"raw_author_name":"Karen G. Welinder","raw_affiliation_strings":["Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut for Bioteknologi, Aalborg Universitet, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark, Dipartimento di Chimica, Universit\u00e1 di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy, Protein Structure Group, Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark, LENS-European Laboratory for Non Linear Spectroscopy, Largo Fermi 2, I-50125 Firenze, Italy, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5036518743"],"corresponding_institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1314107994","https://openalex.org/I2800060819","https://openalex.org/I45084792","https://openalex.org/I891191580"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.2334,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.85781783,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"40","issue":"37","first_page":"11013","last_page":"11021"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.47749999165534973,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.47749999165534973,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.2280000001192093,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11136","display_name":"Enzyme-mediated dye degradation","score":0.1412000060081482,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peroxidase","display_name":"peroxidase","score":0.6890000104904175},{"id":"https://openalex.org/keywords/heme-iron-coordination","display_name":"heme iron coordination","score":0.8119999766349792},{"id":"https://openalex.org/keywords/lignification","display_name":"lignification","score":0.7799999713897705},{"id":"https://openalex.org/keywords/lignin-biosynthesis","display_name":"lignin biosynthesis","score":0.8659999966621399},{"id":"https://openalex.org/keywords/coniferyl-alcohol","display_name":"coniferyl alcohol","score":0.8389999866485596},{"id":"https://openalex.org/keywords/p-coumaryl-alcohol","display_name":"p-coumaryl alcohol","score":0.847000002861023},{"id":"https://openalex.org/keywords/sinapyl-alcohol","display_name":"sinapyl alcohol","score":0.9599999785423279},{"id":"https://openalex.org/keywords/substrate-binding-site","display_name":"substrate binding site","score":0.5809999704360962},{"id":"https://openalex.org/keywords/enzyme-specificity","display_name":"enzyme specificity","score":0.48399999737739563},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.3779999911785126},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.6190000176429749},{"id":"https://openalex.org/keywords/heme-spectroscopy","display_name":"heme spectroscopy","score":0.3449999988079071},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.8204643726348877},{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.7652052640914917},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7385814189910889},{"id":"https://openalex.org/C2777676563","wikidata":"https://www.wikidata.org/wiki/Q413665","display_name":"Horseradish peroxidase","level":3,"score":0.6397808790206909},{"id":"https://openalex.org/C2781340169","wikidata":"https://www.wikidata.org/wiki/Q7315737","display_name":"Resonance Raman spectroscopy","level":3,"score":0.5980604887008667},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5315917134284973},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3482220768928528},{"id":"https://openalex.org/C40003534","wikidata":"https://www.wikidata.org/wiki/Q862228","display_name":"Raman spectroscopy","level":2,"score":0.33991023898124695},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3241865038871765},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003373","descriptor_name":"Coumaric Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006735","descriptor_name":"Horseradish Peroxidase","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D006735","descriptor_name":"Horseradish Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006735","descriptor_name":"Horseradish Peroxidase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010544","descriptor_name":"Peroxidases","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D010544","descriptor_name":"Peroxidases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010544","descriptor_name":"Peroxidases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1021/bi010661o","doi":"https://doi.org/10.1021/bi010661o","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi010661o","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:11551197","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11551197","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:flore.unifi.it:2158/310954","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2158/310954","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/3fe52f60-74c7-11db-bee9-02004c4f4f50","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/3fe52f60-74c7-11db-bee9-02004c4f4f50","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nielsen , K L , Indiani , C , Henriksen , A , Feis , A , Becucci , M , Gajhede , M , Smulevich , G & Welinder , K G 2001 , ' Differential Activity and Structure of Highly Similar Peroxidases. Spectroscopic, Crystallographic, and Enzymatic Analyses of Lignifying Arabidopsis thaliana Peroxidase A2 and Horseradish Peroxidase A2 ' , Biochemistry , no. 40 , pp. 11013-11021 .","raw_type":"article"},{"id":"pmh:oai:pure.atira.dk:publications/288d6fe0-8092-11db-8b97-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://vbn.aau.dk/da/publications/288d6fe0-8092-11db-8b97-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401731","display_name":"VBN Forskningsportal (Aalborg Universitet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I891191580","host_organization_name":"Aalborg University","host_organization_lineage":["https://openalex.org/I891191580"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nielsen, K L, Indiani, C, Henriksen, A, Feis, A, Becucci, M, Gajhede, M, Smulevich, G & Welinder, K G 2001, 'Differential activity and structure of highly similar peroxidases : spectroscopic, crystallographic, and enzymatic analyses of lignifying Arabidopsis thaliana peroxidase A2, and horseradish peroxidase A2', Biochemistry, vol. 37, pp. 11013-11021.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W634482240","https://openalex.org/W1480600051","https://openalex.org/W1803620352","https://openalex.org/W1970552555","https://openalex.org/W1975118350","https://openalex.org/W1986191025","https://openalex.org/W1990805188","https://openalex.org/W1993835332","https://openalex.org/W2016812184","https://openalex.org/W2020753969","https://openalex.org/W2028895306","https://openalex.org/W2061836105","https://openalex.org/W2089132302","https://openalex.org/W2094207096","https://openalex.org/W2107175487","https://openalex.org/W2166827931","https://openalex.org/W2197678796","https://openalex.org/W2311358531","https://openalex.org/W2315870007","https://openalex.org/W2318378584","https://openalex.org/W2418888804"],"related_works":["https://openalex.org/W2011314397","https://openalex.org/W1999727524","https://openalex.org/W251483083","https://openalex.org/W2088359937","https://openalex.org/W1600763344","https://openalex.org/W4403852223","https://openalex.org/W2342784076","https://openalex.org/W2019423080","https://openalex.org/W2512169039","https://openalex.org/W2031981922"],"abstract_inverted_index":{"Anionic":[0],"Arabidopsis":[1,176],"thaliana":[2],"peroxidase":[3,23],"ATP":[4,30,113,132,168,189,231,242,292,342],"A2":[5,31,64,114,133,138,169,190,218,243,250],"was":[6,244],"expressed":[7],"in":[8,65,87,175,217,223,264,354],"Escherichia":[9],"coli":[10],"and":[11,95,121,134,143,152,171,178,194,235,285,291,313,324,334,358,374],"used":[12],"as":[13],"a":[14,40,254],"model":[15],"for":[16,230,268,320,341],"the":[17,91,105,127,184,202,207,349,369],"95%":[18],"identical":[19],"commercially":[20],"available":[21],"horseradish":[22],"HRP":[24,63,137,233,236,249,289,321],"A2.":[25],"The":[26,238,278,345,362],"crystal":[27],"structure":[28,375],"of":[29,62,109,112,130,180,188,206,241,248,280,303,348,365,371],"at":[32,36,67,100,141,257,377],"1.45":[33],"A":[34,45],"resolution":[35],"100":[37],"K":[38],"showed":[39,80,125],"water":[41],"molecule":[42],"only":[43,216],"2.1":[44],"from":[46,146],"heme":[47,82,110,128],"iron":[48,111],"[Ostergaard,":[49],"L.,":[50],"et":[51,72,162],"al.":[52,73,163],"(2000)":[53,164],"Plant":[54],"Mol.":[55],"Biol.":[56],"44,":[57],"231-243],":[58],"whereas":[59],"spectroscopic":[60],"studies":[61,99],"solution":[66,96],"room":[68,101,147],"temperature":[69,102,148],"[Feis,":[70],"A.,":[71],"(1998)":[74],"J.":[75],"Raman":[76,98,123],"Spectrosc.":[77],"29,":[78],"933-938]":[79],"five-coordinated":[81],"iron,":[83],"which":[84],"is":[85,115,352],"common":[86],"peroxidases.":[88,160,225],"Presented":[89],"here,":[90],"X-ray":[92],"crystallographic,":[93],"single-crystal,":[94],"resonance":[97,122],"confirmed":[103],"that":[104,126,167,192,247],"sixth":[106],"coordination":[107],"position":[108],"essentially":[116],"vacant.":[117],"Furthermore,":[118],"electronic":[119],"absorption":[120],"spectroscopy":[124],"environments":[129],"recombinant":[131],"glycosylated":[135],"plant":[136,159],"are":[139,153,364],"indistinguishable":[140],"neutral":[142],"alkaline":[144],"pH,":[145],"to":[149,212,356,368],"12":[150],"K,":[151],"highly":[154],"flexible":[155],"compared":[156],"with":[157,270],"other":[158],"Ostergaard":[161],"also":[165,222],"demonstrated":[166,260],"expression":[170],"lignin":[172,181],"formation":[173],"coincide":[174],"tissues,":[177],"docking":[179],"precursors":[182],"into":[183],"substrate":[185],"binding":[186],"site":[187],"predicted":[191],"coniferyl":[193,281],"p-coumaryl":[195],"alcohols":[196],"were":[197],"good":[198],"substrates.":[199],"In":[200],"contrast,":[201],"additional":[203],"methoxy":[204],"group":[205],"sinapyl":[208],"moiety":[209],"gave":[210,295],"rise":[211],"steric":[213],"hindrance,":[214],"not":[215],"type":[219],"peroxidases":[220],"but":[221,297],"all":[224],"We":[226],"confirm":[227],"these":[228],"predictions":[229],"A2,":[232,234,290,293,322,343],"C.":[237],"specific":[239],"activity":[240],"lower":[245],"than":[246],"(pH":[251],"4-8),":[252],"although":[253],"steady-state":[255],"study":[256],"pH":[258],"5":[259],"very":[261],"little":[262],"difference":[263],"their":[265],"rate":[266,301],"constants":[267,302],"reaction":[269],"H2O2":[271],"(k1":[272],"=":[273],"1.0":[274],"microM(-1)":[275,317,338],"x":[276,318,339],"s(-1).":[277],"oxidation":[279],"alcohol,":[282],"ferulic,":[283],"p-coumaric,":[284],"sinapic":[286],"acids":[287],"by":[288],"however,":[294],"modest":[296],"significantly":[298],"different":[299],"k3":[300],"8.7":[304],"+/-":[305,308,311,315,326,329,332,336],"0.3,":[306],"4.0":[307],"0.2,":[309,327],"0.70":[310],"0.03,":[312],"0.04":[314],"0.2":[316],"s(-1)":[319,340],"respectively,":[323],"4.6":[325],"2.3":[328],"0.1,":[330],"0.25":[331],"0.01,":[333],"0.01":[335],"0.004":[337],"respectively.":[344],"structural":[346],"origin":[347],"differential":[350],"reactivity":[351],"discussed":[353],"relation":[355],"glycosylation":[357],"amino":[359],"acid":[360],"substitutions.":[361],"results":[363],"general":[366],"importance":[367],"use":[370],"homologous":[372],"models":[373],"determination":[376],"low":[378],"temperatures.":[379]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
