{"id":"https://openalex.org/W1995970599","doi":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","title":"Cytokines Required for Induction of Histocompatibility Leukocyte Antigen\u2010class I\u2010restricted and Tumor\u2010specific Cytotoxic T Lymphocytes by a SART1\u2010derived Peptide","display_name":"Cytokines Required for Induction of Histocompatibility Leukocyte Antigen\u2010class I\u2010restricted and Tumor\u2010specific Cytotoxic T Lymphocytes by a SART1\u2010derived Peptide","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W1995970599","doi":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","mag":"1995970599","pmid":"https://pubmed.ncbi.nlm.nih.gov/10551332","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5926162"},"language":"en","primary_location":{"id":"doi:10.1111/j.1349-7006.1999.tb00849.x","doi":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1999.tb00849.x","source":{"id":"https://openalex.org/S4210193983","display_name":"Japanese Journal of Cancer Research","issn_l":"0910-5050","issn":["0910-5050","1344-6428","1876-4673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Cancer Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1999.tb00849.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112938833","display_name":"Kazuko Matsunaga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuko Matsunaga","raw_affiliation_strings":["Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy","Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy","institution_ids":["https://openalex.org/I105296287"]},{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110124663","display_name":"Masanobu Nakao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanobu Nakao","raw_affiliation_strings":["Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112250103","display_name":"Kazuhiro Masuoka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuhiro Masuoka","raw_affiliation_strings":["Departments of Internal Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Internal Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109983509","display_name":"Yoshiko Inoue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiko Inoue","raw_affiliation_strings":["Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080346198","display_name":"Rumi Gouhara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Rumi Gouhara","raw_affiliation_strings":["Departments of Internal Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Internal Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108750254","display_name":"Toshihiro Imaizumi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihiro Imaizumi","raw_affiliation_strings":["Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048369624","display_name":"Shinya Nishizaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinya Nishizaka","raw_affiliation_strings":["Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111616386","display_name":"Kyogo Itoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kyogo Itoh","raw_affiliation_strings":["Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","Departments of Immunology, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Vaccine Development Division of Kurume University Research Center for Innovative Cancer Therapy, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]},{"raw_affiliation_string":"Departments of Immunology, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011","institution_ids":["https://openalex.org/I105296287"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111616386"],"corresponding_institution_ids":["https://openalex.org/I105296287"],"apc_list":null,"apc_paid":null,"fwci":0.1091,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.38148099,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"90","issue":"9","first_page":"1007","last_page":"1015"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tumor-specific-cytotoxic-t-lymphocytes","display_name":"tumor-specific cytotoxic T lymphocytes","score":0.9200000166893005},{"id":"https://openalex.org/keywords/hla-a24","display_name":"HLA-A24","score":0.8119999766349792},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.8640000224113464},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.9779999852180481},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.8989999890327454},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.8669999837875366},{"id":"https://openalex.org/keywords/antigen-presenting-cells","display_name":"antigen-presenting cells","score":0.953000009059906},{"id":"https://openalex.org/keywords/gm-csf","display_name":"GM-CSF","score":0.7269999980926514},{"id":"https://openalex.org/keywords/ctl-induction","display_name":"CTL induction","score":0.5149999856948853},{"id":"https://openalex.org/keywords/tumor-rejection-antigens","display_name":"tumor rejection antigens","score":0.6480000019073486},{"id":"https://openalex.org/keywords/peptide-immunotherapy","display_name":"peptide immunotherapy","score":0.7630000114440918},{"id":"https://openalex.org/keywords/tumor-specific-immunity","display_name":"tumor-specific immunity","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.795029878616333},{"id":"https://openalex.org/C147969180","wikidata":"https://www.wikidata.org/wiki/Q5014579","display_name":"CTL*","level":4,"score":0.707593560218811},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6520609855651855},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5754433274269104},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4936734139919281},{"id":"https://openalex.org/C2780841837","wikidata":"https://www.wikidata.org/wiki/Q24741149","display_name":"Interferon gamma","level":3,"score":0.48917511105537415},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.48730719089508057},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.47680899500846863},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.45771709084510803},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4522252678871155},{"id":"https://openalex.org/C149532602","wikidata":"https://www.wikidata.org/wiki/Q2409681","display_name":"Interleukin 12","level":4,"score":0.4191417098045349},{"id":"https://openalex.org/C83464605","wikidata":"https://www.wikidata.org/wiki/Q575296","display_name":"Antigen presentation","level":4,"score":0.411324679851532},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.40359508991241455},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.2909647226333618},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.1906798779964447},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09089702367782593},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015234","descriptor_name":"HLA-A Antigens","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D015234","descriptor_name":"HLA-A Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015847","descriptor_name":"Interleukin-4","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016178","descriptor_name":"Granulocyte-Macrophage Colony-Stimulating Factor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017411","descriptor_name":"Ribonucleoproteins, Small Nuclear","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059871","descriptor_name":"HLA-A24 Antigen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1111/j.1349-7006.1999.tb00849.x","doi":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1999.tb00849.x","source":{"id":"https://openalex.org/S4210193983","display_name":"Japanese Journal of Cancer Research","issn_l":"0910-5050","issn":["0910-5050","1344-6428","1876-4673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Cancer Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4864854","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5926162","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:10551332","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10551332","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese journal of cancer research : Gann","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5926162","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5926162/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jpn J Cancer Res","raw_type":"Text"},{"id":"mag:2338311551","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000342769","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1111/j.1349-7006.1999.tb00849.x","doi":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1349-7006.1999.tb00849.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1999.tb00849.x","source":{"id":"https://openalex.org/S4210193983","display_name":"Japanese Journal of Cancer Research","issn_l":"0910-5050","issn":["0910-5050","1344-6428","1876-4673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Cancer Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1995970599.pdf","grobid_xml":"https://content.openalex.org/works/W1995970599.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W118853962","https://openalex.org/W1026537797","https://openalex.org/W1480063679","https://openalex.org/W1555492741","https://openalex.org/W1585987942","https://openalex.org/W1588193878","https://openalex.org/W1639400191","https://openalex.org/W1673344236","https://openalex.org/W1724933401","https://openalex.org/W1983806918","https://openalex.org/W1986697473","https://openalex.org/W1987387600","https://openalex.org/W2018077354","https://openalex.org/W2038639621","https://openalex.org/W2048181920","https://openalex.org/W2053323609","https://openalex.org/W2053984506","https://openalex.org/W2063574986","https://openalex.org/W2066964346","https://openalex.org/W2071165876","https://openalex.org/W2072589708","https://openalex.org/W2096385955","https://openalex.org/W2101771134","https://openalex.org/W2105584714","https://openalex.org/W2106135817","https://openalex.org/W2115687350","https://openalex.org/W2116382205","https://openalex.org/W2116716017","https://openalex.org/W2118271123","https://openalex.org/W2120831204","https://openalex.org/W2122507780","https://openalex.org/W2124376809","https://openalex.org/W2130185552","https://openalex.org/W2136555855","https://openalex.org/W2148368831","https://openalex.org/W2149940155","https://openalex.org/W2397128349"],"related_works":["https://openalex.org/W2338311551","https://openalex.org/W2072589708","https://openalex.org/W2087403805","https://openalex.org/W2102155446","https://openalex.org/W1967574834","https://openalex.org/W2010745752","https://openalex.org/W2099913345","https://openalex.org/W653813462","https://openalex.org/W2118683743","https://openalex.org/W1981977181"],"abstract_inverted_index":{"Although":[0],"there":[1],"have":[2],"been":[3],"several":[4,144],"reports":[5],"on":[6],"peptides":[7],"of":[8,13,49,57,70,75,92,139,146,151,158,170,203,217,227,240,246,254],"human":[9],"tumor-rejection":[10],"antigens":[11],"capable":[12,56],"inducing":[14,58],"histocompatibility":[15],"leukocyte":[16],"antigen":[17],"(HLA)-class":[18],"I-restricted":[19],"and":[20,60,137,181,196,205,210,243,249],"tumor-specific":[21,61,247],"cytotoxic":[22],"T":[23],"lymphocytes":[24],"(CTLs),":[25],"it":[26],"is":[27,55],"not":[28,89,106],"yet":[29],"clear":[30],"which":[31,54,219],"cytokines":[32,95],"are":[33,198,212,222,232],"required":[34,45,188,223],"for":[35,46,134,141,214,224,236,251],"CTL":[36,100],"induction.":[37],"This":[38,110,148],"study":[39],"has":[40],"investigated":[41],"the":[42,93,98,135,142,156,164,171,201,215,241,252],"cytokine":[43],"combinations":[44],"optimal":[47],"induction":[48,216],"CTLs":[50,62,140,152],"by":[51,115,129,155],"SART1(690-698)":[52],"peptide,":[53],"HLA-A24-restricted":[59],"in":[63,102,107,123,200,220,234],"peripheral":[64],"blood":[65],"mononuclear":[66],"cells":[67,77,174],"(PBMCs).":[68],"Pretreatment":[69],"PBMCs":[71,178],"as":[72,189],"a":[73,237],"source":[74],"antigen-presenting":[76],"(APCs)":[78],"with":[79,86,90,126,179],"interferon":[80],"(IFN)-gamma,":[81],"or":[82,119,161],"to":[83,163],"some":[84],"extent":[85],"IFN-alpha,":[87],"but":[88,105],"any":[91],"other":[94],"tested,":[96],"augmented":[97],"peptide-induced":[99],"activity":[101],"HLA-A24":[103,108],"heterozygotes,":[104],"homozygotes.":[109],"IFN-gamma-mediated":[111],"augmentation":[112],"was":[113,132,153],"inhibited":[114,154],"either":[116],"interleukin":[117],"(IL)-4":[118],"IL-10.":[120],"IL-2":[121,165,197],"alone":[122],"culture,":[124],"along":[125],"weekly":[127],"stimulation":[128],"peptide-pulsed":[130],"APCs,":[131],"sufficient":[133],"differentiation":[136],"proliferation":[138],"initial":[143],"weeks":[145],"culture.":[147,166],"IL-2-mediated":[149],"activation":[150,202],"addition":[157],"IFN-gamma,":[159],"IL-4,":[160],"IL-10":[162],"For":[167],"further":[168,225],"expansion":[169,226],"CTLs,":[172,206],"dendritic":[173],"(DCs)":[175],"induced":[176],"from":[177],"IL-4":[180,211],"granulocyte":[182],"macrophage":[183],"colony-stimulating":[184],"factor":[185],"(GM-CSF)":[186],"were":[187],"APCs.":[190],"These":[191,230],"results":[192,231],"indicate":[193],"that":[194],"IFN-gamma":[195],"important":[199,233],"APCs":[204],"respectively,":[207],"while":[208],"GM-CSF":[209],"needed":[213],"DCs,":[218],"turn":[221],"mature":[228],"CTLs.":[229],"allowing":[235],"better":[238],"understanding":[239],"cellular":[242],"molecular":[244],"basis":[245],"immunity,":[248],"also":[250],"development":[253],"peptide-based":[255],"specific":[256],"immunotherapy.":[257]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}