{"id":"https://openalex.org/W1995968469","doi":"https://doi.org/10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","title":"Hypothalamic regulation of gonadotropin secretion in anorexia nervosa and in starvation","display_name":"Hypothalamic regulation of gonadotropin secretion in anorexia nervosa and in starvation","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W1995968469","doi":"https://doi.org/10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","mag":"1995968469"},"language":"en","primary_location":{"id":"doi:10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","doi":"https://doi.org/10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","is_oa":false,"landing_page_url":"https://doi.org/10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","pdf_url":null,"source":{"id":"https://openalex.org/S74080386","display_name":"International Journal of Eating Disorders","issn_l":"0276-3478","issn":["0276-3478","1098-108X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Eating Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113680683","display_name":"Karl\u2010Martin Pirke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210145969","display_name":"Max Planck Institute of Psychiatry","ror":"https://ror.org/04dq56617","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"K. M. Pirke","raw_affiliation_strings":["Max Planck Institut fur Psychiatric, Munchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institut fur Psychiatric, Munchen, Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022958934","display_name":"Manfred Maximilian Fichter","orcid":"https://orcid.org/0000-0002-8788-4878","observed_orcids":["https://orcid.org/0000-0002-8788-4878"]},"institutions":[{"id":"https://openalex.org/I4210147185","display_name":"Klinik und Poliklinik f\u00fcr Psychiatrie und Psychotherapie","ror":"https://ror.org/03j546b66","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4210147185","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. M. Fichter","raw_affiliation_strings":["Psychiatriesche Klinik der Universitat, Munchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatriesche Klinik der Universitat, Munchen, Germany","institution_ids":["https://openalex.org/I4210147185","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056801795","display_name":"Michael Warnhoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210145969","display_name":"Max Planck Institute of Psychiatry","ror":"https://ror.org/04dq56617","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Warnhoff","raw_affiliation_strings":["Max Planck Institut fur Psychiatric, Munchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institut fur Psychiatric, Munchen, Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061459021","display_name":"Gunter Dorsch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210145969","display_name":"Max Planck Institute of Psychiatry","ror":"https://ror.org/04dq56617","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. Dorsch","raw_affiliation_strings":["Max Planck Institut fur Psychiatric, Munchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institut fur Psychiatric, Munchen, Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019450255","display_name":"Barbara Spyra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210145969","display_name":"Max Planck Institute of Psychiatry","ror":"https://ror.org/04dq56617","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"B. Spyra","raw_affiliation_strings":["Max Planck Institut fur Psychiatric, Munchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institut fur Psychiatric, Munchen, Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210145969"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5113680683"],"corresponding_institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210145969"],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":null,"fwci":0.3825,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.60849057,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"4","first_page":"151","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamic-regulation","display_name":"hypothalamic regulation","score":0.7760000228881836},{"id":"https://openalex.org/keywords/gonadotropin-secretion","display_name":"gonadotropin secretion","score":0.9950000047683716},{"id":"https://openalex.org/keywords/anorexia-nervosa","display_name":"anorexia nervosa","score":0.984000027179718},{"id":"https://openalex.org/keywords/starvation","display_name":"starvation","score":0.9660000205039978},{"id":"https://openalex.org/keywords/gonadotropin-releasing-hormone","display_name":"gonadotropin-releasing hormone","score":0.9819999933242798},{"id":"https://openalex.org/keywords/median-eminence","display_name":"median eminence","score":0.9959999918937683},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.8700000047683716},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.9860000014305115},{"id":"https://openalex.org/keywords/dynorphin","display_name":"dynorphin","score":0.996999979019165},{"id":"https://openalex.org/keywords/prostaglandin-e2","display_name":"prostaglandin E2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/catecholaminergic-system","display_name":"catecholaminergic system","score":0.8939999938011169}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8509407639503479},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8314781785011292},{"id":"https://openalex.org/C2777031586","wikidata":"https://www.wikidata.org/wiki/Q131749","display_name":"Anorexia nervosa","level":3,"score":0.7740057110786438},{"id":"https://openalex.org/C151077648","wikidata":"https://www.wikidata.org/wiki/Q324076","display_name":"Dynorphin","level":5,"score":0.7107263207435608},{"id":"https://openalex.org/C2778782382","wikidata":"https://www.wikidata.org/wiki/Q409770","display_name":"Gonadotropin","level":3,"score":0.6428381204605103},{"id":"https://openalex.org/C2779067335","wikidata":"https://www.wikidata.org/wiki/Q1337712","display_name":"Median eminence","level":3,"score":0.6080716848373413},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.5600190758705139},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.5585715770721436},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.5051620602607727},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4309432804584503},{"id":"https://openalex.org/C2778894405","wikidata":"https://www.wikidata.org/wiki/Q318896","display_name":"Gonadotropin-releasing hormone","level":4,"score":0.4179568886756897},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3972488343715668},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34812361001968384},{"id":"https://openalex.org/C2776394216","wikidata":"https://www.wikidata.org/wiki/Q373822","display_name":"Eating disorders","level":2,"score":0.21256020665168762},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.20028916001319885},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.11762586236000061},{"id":"https://openalex.org/C88016717","wikidata":"https://www.wikidata.org/wiki/Q417189","display_name":"Opioid peptide","level":4,"score":0.09492376446723938},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.06469637155532837},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","doi":"https://doi.org/10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","is_oa":false,"landing_page_url":"https://doi.org/10.1002/1098-108x(198322)2:4<151::aid-eat2260020423>3.0.co;2-q","pdf_url":null,"source":{"id":"https://openalex.org/S74080386","display_name":"International Journal of Eating Disorders","issn_l":"0276-3478","issn":["0276-3478","1098-108X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Eating Disorders","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1969833835","https://openalex.org/W1997553861","https://openalex.org/W1999831221","https://openalex.org/W2023472658","https://openalex.org/W2025824911","https://openalex.org/W2147025933","https://openalex.org/W2992270508"],"related_works":["https://openalex.org/W45895733","https://openalex.org/W2050781195","https://openalex.org/W2092465253","https://openalex.org/W2060621666","https://openalex.org/W2070336422","https://openalex.org/W1969150983","https://openalex.org/W2095436537","https://openalex.org/W2090695956","https://openalex.org/W1967044738","https://openalex.org/W2056751371"],"abstract_inverted_index":{"The":[0,50],"regulation":[1,63],"of":[2,64,70,78],"gonadotropin":[3],"secretion":[4],"was":[5],"studied":[6],"in":[7,10,16,29,46,61],"anorexia":[8],"nervosa,":[9],"voluntarily":[11],"starving":[12],"healthy":[13],"subjects,":[14],"and":[15,48,56,74],"the":[17,39,62,71,79,86],"starved":[18],"rat.":[19],"In":[20],"all":[21],"cases,":[22],"a":[23],"hypothalamic":[24],"disturbance":[25],"is":[26,44],"observed,":[27],"resulting":[28],"an":[30,75],"impaired":[31,87],"ability":[32],"to":[33],"secrete":[34],"gonadotropin-releasing":[35],"hormone":[36],"(CnRH)":[37],"from":[38],"median":[40],"eminence.":[41],"This":[42],"effect":[43],"weight-dependent":[45],"man":[47],"animals.":[49],"central":[51],"neurotransmitters":[52],"noradrenaline,":[53],"dopamine,":[54],"dynorphin,":[55],"prostaglandin":[57],"E2":[58],"are":[59],"involved":[60],"GnRH":[65,88],"release.":[66,89],"A":[67],"decreased":[68],"activity":[69,77],"catecholaminergk":[72],"system":[73,81],"increased":[76],"endorphinergic":[80],"may":[82],"be":[83],"responsible":[84],"for":[85]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}