{"id":"https://openalex.org/W1995932443","doi":"https://doi.org/10.1016/j.semcdb.2014.08.014","title":"Induction and patterning of the metanephric nephron","display_name":"Induction and patterning of the metanephric nephron","publication_year":2014,"publication_date":"2014-09-05","ids":{"openalex":"https://openalex.org/W1995932443","doi":"https://doi.org/10.1016/j.semcdb.2014.08.014","mag":"1995932443","pmid":"https://pubmed.ncbi.nlm.nih.gov/25194660","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4252735"},"language":"en","primary_location":{"id":"doi:10.1016/j.semcdb.2014.08.014","doi":"https://doi.org/10.1016/j.semcdb.2014.08.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.semcdb.2014.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S105347553","display_name":"Seminars in Cell and Developmental Biology","issn_l":"1084-9521","issn":["1084-9521","1096-3634"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Cell & Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4252735","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081052272","display_name":"Lori L. O\u2019Brien","orcid":"https://orcid.org/0000-0002-0741-181X","observed_orcids":["https://orcid.org/0000-0002-0741-181X"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lori L. O\u2019Brien","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003394161","display_name":"Andrew P. McMahon","orcid":"https://orcid.org/0000-0002-3779-1729","observed_orcids":["https://orcid.org/0000-0002-3779-1729"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew P. McMahon","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5081052272"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":{"value":4670,"currency":"USD","value_usd":4670},"apc_paid":null,"fwci":0.8192,"has_fulltext":false,"cited_by_count":69,"citation_normalized_percentile":{"value":0.6382552,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"36","issue":null,"first_page":"31","last_page":"38"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nephron-development","display_name":"nephron development","score":0.781000018119812},{"id":"https://openalex.org/keywords/metanephros","display_name":"metanephros","score":0.8889999985694885},{"id":"https://openalex.org/keywords/nephron-progenitors","display_name":"nephron progenitors","score":0.8880000114440918},{"id":"https://openalex.org/keywords/kidney-development","display_name":"kidney development","score":0.5130000114440918},{"id":"https://openalex.org/keywords/renal-vesicle","display_name":"renal vesicle","score":0.7229999899864197},{"id":"https://openalex.org/keywords/mesenchymal-progenitor-cells","display_name":"mesenchymal progenitor cells","score":0.7429999709129333},{"id":"https://openalex.org/keywords/glomerulus","display_name":"glomeruli","score":0.6110000014305115},{"id":"https://openalex.org/keywords/wilms-tumor","display_name":"Wilms tumor","score":0.8399999737739563},{"id":"https://openalex.org/keywords/kidney-morphogenesis","display_name":"kidney morphogenesis","score":0.6480000019073486},{"id":"https://openalex.org/keywords/proximal-distal-axis","display_name":"proximal-distal axis","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C2781231759","wikidata":"https://www.wikidata.org/wiki/Q58184","display_name":"Nephron","level":3,"score":0.9761335253715515},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.6726524233818054},{"id":"https://openalex.org/C2776340970","wikidata":"https://www.wikidata.org/wiki/Q32838","display_name":"Mesenchyme","level":3,"score":0.6476944088935852},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5729159712791443},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5659512877464294},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4924822747707367},{"id":"https://openalex.org/C2777632694","wikidata":"https://www.wikidata.org/wiki/Q2336077","display_name":"Kidney development","level":4,"score":0.48159071803092957},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4525276720523834},{"id":"https://openalex.org/C138798377","wikidata":"https://www.wikidata.org/wiki/Q7312502","display_name":"Renal stem cell","level":4,"score":0.4271449148654938},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.410664439201355},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.4104255437850952},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.351019024848938},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.2730149030685425},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.18335875868797302},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16432294249534607},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0536322295665741},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009396","descriptor_name":"Wilms Tumor","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D009399","descriptor_name":"Nephrons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009399","descriptor_name":"Nephrons","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038081","descriptor_name":"Organogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051153","descriptor_name":"Wnt Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051880","descriptor_name":"Receptors, Notch","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D060449","descriptor_name":"Wnt Signaling Pathway","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.semcdb.2014.08.014","doi":"https://doi.org/10.1016/j.semcdb.2014.08.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.semcdb.2014.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S105347553","display_name":"Seminars in Cell and Developmental Biology","issn_l":"1084-9521","issn":["1084-9521","1096-3634"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Cell & Developmental Biology","raw_type":"journal-article"},{"id":"pmid:25194660","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25194660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in cell & developmental biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4252735","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4252735","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Semin Cell Dev Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4252735","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4252735","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Semin Cell Dev Biol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4020814076","display_name":"GUDMAP2 - Production of Mouse Strains for Gene Anatomy of the Lower Urinary Tract","funder_award_id":"U01DK094526","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7530705153","display_name":"Repair and regeneration of the nephron","funder_award_id":"LA1-06536","funder_id":"https://openalex.org/F4320306171","funder_display_name":"California Institute for Regenerative Medicine"},{"id":"https://openalex.org/G7795308358","display_name":"Cell Interactions in Development of the Mammalian Kidney","funder_award_id":"R37DK054364","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306171","display_name":"California Institute for Regenerative Medicine","ror":"https://ror.org/033m8b439"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":97,"referenced_works":["https://openalex.org/W35892607","https://openalex.org/W1502534219","https://openalex.org/W1765845624","https://openalex.org/W1873268238","https://openalex.org/W1965035346","https://openalex.org/W1965534679","https://openalex.org/W1971689970","https://openalex.org/W1977032251","https://openalex.org/W1977466966","https://openalex.org/W1978561049","https://openalex.org/W1978869139","https://openalex.org/W1980020302","https://openalex.org/W1982099181","https://openalex.org/W1982684746","https://openalex.org/W1985623793","https://openalex.org/W1987874305","https://openalex.org/W1991148912","https://openalex.org/W1995338323","https://openalex.org/W1997631325","https://openalex.org/W1999089403","https://openalex.org/W2000714884","https://openalex.org/W2001671102","https://openalex.org/W2004410280","https://openalex.org/W2006946978","https://openalex.org/W2007195938","https://openalex.org/W2007281432","https://openalex.org/W2011832831","https://openalex.org/W2012409410","https://openalex.org/W2013609600","https://openalex.org/W2014784548","https://openalex.org/W2015807591","https://openalex.org/W2017990018","https://openalex.org/W2018091219","https://openalex.org/W2021017423","https://openalex.org/W2021695872","https://openalex.org/W2024215958","https://openalex.org/W2027060853","https://openalex.org/W2027171099","https://openalex.org/W2029229719","https://openalex.org/W2029706942","https://openalex.org/W2032559063","https://openalex.org/W2038518341","https://openalex.org/W2039309643","https://openalex.org/W2046310224","https://openalex.org/W2046518908","https://openalex.org/W2047244839","https://openalex.org/W2049652771","https://openalex.org/W2050032678","https://openalex.org/W2050627146","https://openalex.org/W2050896209","https://openalex.org/W2053489483","https://openalex.org/W2053946192","https://openalex.org/W2056109978","https://openalex.org/W2063936800","https://openalex.org/W2063947701","https://openalex.org/W2064199615","https://openalex.org/W2064862709","https://openalex.org/W2066484100","https://openalex.org/W2074329168","https://openalex.org/W2075695335","https://openalex.org/W2082689543","https://openalex.org/W2082806151","https://openalex.org/W2083356835","https://openalex.org/W2083450751","https://openalex.org/W2084176144","https://openalex.org/W2084585178","https://openalex.org/W2086332492","https://openalex.org/W2088066303","https://openalex.org/W2088424142","https://openalex.org/W2092946806","https://openalex.org/W2094059784","https://openalex.org/W2098135409","https://openalex.org/W2102636621","https://openalex.org/W2105388550","https://openalex.org/W2107705756","https://openalex.org/W2114207717","https://openalex.org/W2114245705","https://openalex.org/W2116228354","https://openalex.org/W2117606428","https://openalex.org/W2119284420","https://openalex.org/W2124415162","https://openalex.org/W2124852687","https://openalex.org/W2128724412","https://openalex.org/W2131924342","https://openalex.org/W2132124458","https://openalex.org/W2133545802","https://openalex.org/W2136825322","https://openalex.org/W2143416290","https://openalex.org/W2145111609","https://openalex.org/W2146721843","https://openalex.org/W2150715319","https://openalex.org/W2152046643","https://openalex.org/W2154992599","https://openalex.org/W2162649803","https://openalex.org/W2163406006","https://openalex.org/W2206997096","https://openalex.org/W2344364145"],"related_works":["https://openalex.org/W2032989881","https://openalex.org/W2333229695","https://openalex.org/W2023284816","https://openalex.org/W1546093545","https://openalex.org/W2103313183","https://openalex.org/W229872713","https://openalex.org/W2888376375","https://openalex.org/W2768155463","https://openalex.org/W2162649803","https://openalex.org/W2030271221"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}