{"id":"https://openalex.org/W1995706284","doi":"https://doi.org/10.1042/bst0351543","title":"New parameters controlling the effect of temperature on enzyme activity","display_name":"New parameters controlling the effect of temperature on enzyme activity","publication_year":2007,"publication_date":"2007-11-23","ids":{"openalex":"https://openalex.org/W1995706284","doi":"https://doi.org/10.1042/bst0351543","mag":"1995706284","pmid":"https://pubmed.ncbi.nlm.nih.gov/18031263"},"language":"en","primary_location":{"id":"doi:10.1042/bst0351543","doi":"https://doi.org/10.1042/bst0351543","is_oa":false,"landing_page_url":"https://doi.org/10.1042/bst0351543","pdf_url":null,"source":{"id":"https://openalex.org/S137670264","display_name":"Biochemical Society Transactions","issn_l":"0300-5127","issn":["0300-5127","1470-8752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Society Transactions","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111793811","display_name":"Roy M. Daniel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"R.M. Daniel","raw_affiliation_strings":["Thermophile Research Unit, School of Science and Engineering, University of Waikato, Hamilton, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermophile Research Unit, School of Science and Engineering, University of Waikato, Hamilton, New Zealand","institution_ids":["https://openalex.org/I52179390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030081364","display_name":"Michael J. Danson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M.J. Danson","raw_affiliation_strings":["Centre for Extremophile Research and Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Extremophile Research and Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, U.K","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028871966","display_name":"Robert Eisenthal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. Eisenthal","raw_affiliation_strings":["Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, U.K","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114928314","display_name":"Charles K. Lee","orcid":"https://orcid.org/0000-0002-6562-4733","observed_orcids":["https://orcid.org/0000-0002-6562-4733"]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"C.K. Lee","raw_affiliation_strings":["Thermophile Research Unit, School of Science and Engineering, University of Waikato, Hamilton, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermophile Research Unit, School of Science and Engineering, University of Waikato, Hamilton, New Zealand","institution_ids":["https://openalex.org/I52179390"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031121593","display_name":"Michelle E. Peterson","orcid":"https://orcid.org/0000-0002-6413-322X","observed_orcids":["https://orcid.org/0000-0002-6413-322X"]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"M.E. Peterson","raw_affiliation_strings":["Thermophile Research Unit, School of Science and Engineering, University of Waikato, Hamilton, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermophile Research Unit, School of Science and Engineering, University of Waikato, Hamilton, New Zealand","institution_ids":["https://openalex.org/I52179390"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.544,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.58541253,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"35","issue":"6","first_page":"1543","last_page":"1546"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.5365999937057495,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.5365999937057495,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.17110000550746918,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.12880000472068787,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enzyme-thermal-inactivation","display_name":"enzyme thermal inactivation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/equilibrium-model","display_name":"equilibrium model","score":0.8370000123977661},{"id":"https://openalex.org/keywords/reversible-enzyme-inactivation","display_name":"reversible enzyme inactivation","score":0.7519999742507935},{"id":"https://openalex.org/keywords/thermal-parameters","display_name":"thermal parameters","score":0.597000002861023},{"id":"https://openalex.org/keywords/enzyme-technology","display_name":"enzyme technology","score":0.7540000081062317}],"concepts":[{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.7125216126441956},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.6101248264312744},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5560624599456787},{"id":"https://openalex.org/C28212737","wikidata":"https://www.wikidata.org/wiki/Q5381543","display_name":"Enzyme assay","level":3,"score":0.5365517139434814},{"id":"https://openalex.org/C204530211","wikidata":"https://www.wikidata.org/wiki/Q752823","display_name":"Thermal","level":2,"score":0.4853769540786743},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.39420825242996216},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2684019207954407},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17076468467712402},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1352376639842987}],"mesh":[{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004798","descriptor_name":"Enzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004798","descriptor_name":"Enzymes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015202","descriptor_name":"Protein Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1042/bst0351543","doi":"https://doi.org/10.1042/bst0351543","is_oa":false,"landing_page_url":"https://doi.org/10.1042/bst0351543","pdf_url":null,"source":{"id":"https://openalex.org/S137670264","display_name":"Biochemical Society Transactions","issn_l":"0300-5127","issn":["0300-5127","1470-8752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Society Transactions","raw_type":"journal-article"},{"id":"pmid:18031263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18031263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Society transactions","raw_type":"Journal Article"},{"id":"pmh:oai:researchcommons.waikato.ac.nz:10289/4437","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10289/4437","pdf_url":null,"source":{"id":"https://openalex.org/S4306400944","display_name":"Research Commons (University of Waikato)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52179390","host_organization_name":"University of Waikato","host_organization_lineage":["https://openalex.org/I52179390"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1567025536","https://openalex.org/W1633704547","https://openalex.org/W1748668484","https://openalex.org/W1977962237","https://openalex.org/W1983011027","https://openalex.org/W2022280363","https://openalex.org/W2045994733","https://openalex.org/W2050257137","https://openalex.org/W2057798572","https://openalex.org/W2060620101","https://openalex.org/W2061521483","https://openalex.org/W2064614137","https://openalex.org/W2079257291","https://openalex.org/W2132465010","https://openalex.org/W2329952272","https://openalex.org/W4205666823"],"related_works":["https://openalex.org/W1980776051","https://openalex.org/W2061521483","https://openalex.org/W125405689","https://openalex.org/W2994229845","https://openalex.org/W2019200192","https://openalex.org/W159809027","https://openalex.org/W2060620101","https://openalex.org/W7096321695","https://openalex.org/W91085162","https://openalex.org/W2117856173"],"abstract_inverted_index":{"Arising":[0],"from":[1],"careful":[2],"measurements":[3],"of":[4,8,25,34,41,85,88,108,116,125],"the":[5,13,23,32,77,86,96,106,109,114,117,120],"thermal":[6,64,71],"behaviour":[7],"enzymes,":[9,126],"a":[10,42,82],"new":[11,70],"model,":[12],"Equilibrium":[14,110],"Model,":[15],"has":[16],"been":[17],"developed":[18],"to":[19,62,101],"explain":[20],"more":[21],"fully":[22],"effects":[24],"temperature":[26,35,89],"on":[27,36,90],"enzymes.":[28],"The":[29],"model":[30],"describes":[31],"effect":[33,87],"enzyme":[37,57,91],"activity":[38,58],"in":[39,60],"terms":[40],"rapidly":[43],"reversible":[44,54],"active-inactive":[45,78],"(but":[46],"not":[47],"denatured)":[48],"transition,":[49,79],"revealing":[50],"an":[51],"additional":[52],"and":[53,74,80,98,113,123,127],"mechanism":[55],"for":[56,105,119,128],"loss":[59],"addition":[61],"irreversible":[63],"inactivation":[65],"at":[66],"high":[67],"temperatures.":[68],"Two":[69],"parameters,":[72,112],"T(eq)":[73],"DeltaH(eq),":[75],"describe":[76,94],"enable":[81],"complete":[83],"description":[84],"activity.":[92],"We":[93],"here":[95],"Model":[97,111,118],"its":[99],"fit":[100],"experimental":[102],"data,":[103],"methods":[104],"determination":[107],"implications":[115],"environmental":[121],"adaptation":[122],"evolution":[124],"biotechnology.":[129]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}