{"id":"https://openalex.org/W1995697172","doi":"https://doi.org/10.1016/s0360-3016(99)00472-1","title":"Benefits of adjuvant radiotherapy after radical resection of locally advanced main hepatic duct carcinoma","display_name":"Benefits of adjuvant radiotherapy after radical resection of locally advanced main hepatic duct carcinoma","publication_year":2000,"publication_date":"2000-02-01","ids":{"openalex":"https://openalex.org/W1995697172","doi":"https://doi.org/10.1016/s0360-3016(99)00472-1","mag":"1995697172","pmid":"https://pubmed.ncbi.nlm.nih.gov/10701737"},"language":"en","primary_location":{"id":"doi:10.1016/s0360-3016(99)00472-1","doi":"https://doi.org/10.1016/s0360-3016(99)00472-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0360-3016(99)00472-1","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109547886","display_name":"Takeshi Todoroki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takeshi Todoroki","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan. todorov@md.tsukuba.ac.jp","Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan. todorov@md.tsukuba.ac.jp","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110439749","display_name":"Kiyoshi Ohara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyoshi Ohara","raw_affiliation_strings":["Department of Radiology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110392176","display_name":"Toru Kawamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Kawamoto","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018972630","display_name":"Naoto Koike","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Koike","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082520378","display_name":"Sadao Yoshida","orcid":"https://orcid.org/0000-0001-9080-5213","observed_orcids":["https://orcid.org/0000-0001-9080-5213"]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sadao Yoshida","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108450497","display_name":"Hironobu Kashiwagi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hironobu Kashiwagi","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Masaaki Otsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Otsuka","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047894538","display_name":"Katashi Fukao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katashi Fukao","raw_affiliation_strings":["Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-Shi, Japan","institution_ids":["https://openalex.org/I146399215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5109547886"],"corresponding_institution_ids":["https://openalex.org/I146399215"],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":6.0733,"has_fulltext":false,"cited_by_count":193,"citation_normalized_percentile":{"value":0.96357258,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"46","issue":"3","first_page":"581","last_page":"587"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.8759999871253967,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.8759999871253967,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.07670000195503235,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hilar-cholangiocarcinoma","display_name":"hilar cholangiocarcinoma","score":0.9860000014305115},{"id":"https://openalex.org/keywords/adjuvant-radiotherapy","display_name":"adjuvant radiotherapy","score":0.9879999756813049},{"id":"https://openalex.org/keywords/intraoperative-radiotherapy","display_name":"intraoperative radiotherapy","score":0.8849999904632568},{"id":"https://openalex.org/keywords/postoperative-radiotherapy","display_name":"postoperative radiotherapy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/radical-hepatectomy","display_name":"radical hepatectomy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/local-regional-control","display_name":"local-regional control","score":0.7329999804496765},{"id":"https://openalex.org/keywords/5-year-survival","display_name":"five-year survival","score":0.8849999904632568},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9570322632789612},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6774279475212097},{"id":"https://openalex.org/C3018454096","wikidata":"https://www.wikidata.org/wiki/Q2481887","display_name":"Adjuvant radiotherapy","level":3,"score":0.6077338457107544},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5427797436714172},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.4702523946762085},{"id":"https://openalex.org/C2776640808","wikidata":"https://www.wikidata.org/wiki/Q475260","display_name":"Klatskin tumor","level":3,"score":0.4404500126838684},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4180557131767273},{"id":"https://openalex.org/C159110652","wikidata":"https://www.wikidata.org/wiki/Q17078201","display_name":"Resection","level":2,"score":0.34019505977630615},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.17773878574371338}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001650","descriptor_name":"Bile Duct Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001650","descriptor_name":"Bile Duct Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D001650","descriptor_name":"Bile Duct Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006500","descriptor_name":"Hepatic Duct, Common","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018714","descriptor_name":"Radiotherapy, Adjuvant","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0360-3016(99)00472-1","doi":"https://doi.org/10.1016/s0360-3016(99)00472-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0360-3016(99)00472-1","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},{"id":"pmid:10701737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10701737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of radiation oncology, biology, physics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W46540264","https://openalex.org/W58575840","https://openalex.org/W125146562","https://openalex.org/W185604426","https://openalex.org/W1969511539","https://openalex.org/W1971542660","https://openalex.org/W1971652279","https://openalex.org/W1972002667","https://openalex.org/W1984862908","https://openalex.org/W1986154367","https://openalex.org/W1996696052","https://openalex.org/W2002946012","https://openalex.org/W2009612552","https://openalex.org/W2010609119","https://openalex.org/W2025966046","https://openalex.org/W2026175981","https://openalex.org/W2027729453","https://openalex.org/W2029572375","https://openalex.org/W2031973729","https://openalex.org/W2036940815","https://openalex.org/W2043341842","https://openalex.org/W2052532856","https://openalex.org/W2057433926","https://openalex.org/W2061004798","https://openalex.org/W2061342811","https://openalex.org/W2070963385","https://openalex.org/W2082291755","https://openalex.org/W2084582052","https://openalex.org/W2091880724","https://openalex.org/W2093723107","https://openalex.org/W2134526246","https://openalex.org/W2147548276","https://openalex.org/W2148702187","https://openalex.org/W2259619651","https://openalex.org/W2338933759","https://openalex.org/W2394911519","https://openalex.org/W2413627081","https://openalex.org/W2469583109","https://openalex.org/W4239180165"],"related_works":["https://openalex.org/W2259619651","https://openalex.org/W2069174209","https://openalex.org/W3198318776","https://openalex.org/W2580551060","https://openalex.org/W2803329216","https://openalex.org/W2092163967","https://openalex.org/W2312305408","https://openalex.org/W3096113279","https://openalex.org/W2016671607","https://openalex.org/W2000855462"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}