{"id":"https://openalex.org/W1995606247","doi":"https://doi.org/10.1016/0165-2478(88)90062-4","title":"Tac expression induced by Epstein \u2014 Barr virus is restricted on non-transformable B lymphocytes","display_name":"Tac expression induced by Epstein \u2014 Barr virus is restricted on non-transformable B lymphocytes","publication_year":1988,"publication_date":"1988-05-01","ids":{"openalex":"https://openalex.org/W1995606247","doi":"https://doi.org/10.1016/0165-2478(88)90062-4","mag":"1995606247","pmid":"https://pubmed.ncbi.nlm.nih.gov/2837437"},"language":"en","primary_location":{"id":"doi:10.1016/0165-2478(88)90062-4","doi":"https://doi.org/10.1016/0165-2478(88)90062-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-2478(88)90062-4","pdf_url":null,"source":{"id":"https://openalex.org/S71256826","display_name":"Immunology Letters","issn_l":"0165-2478","issn":["0165-2478","1879-0542"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunology Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087123692","display_name":"Jean Gosselin","orcid":"https://orcid.org/0000-0002-2244-4898","observed_orcids":["https://orcid.org/0000-0002-2244-4898"]},"institutions":[{"id":"https://openalex.org/I4405287452","display_name":"Centre Armand-Frappier Sant\u00e9 Biotechnologie","ror":"https://ror.org/0562xaa66","country_code":"CA","type":"education","lineage":["https://openalex.org/I39481719","https://openalex.org/I4405287452","https://openalex.org/I49663120"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Jean Gosselin","raw_affiliation_strings":["Centre de Recherche en Immunologie, Institut Armand-Frappier, Ville de Laval, Qu\u00e9bec, Canada","Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche en Immunologie, Institut Armand-Frappier, Ville de Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I4405287452"]},{"raw_affiliation_string":"Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I4405287452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049700713","display_name":"Marcel Desrosiers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287452","display_name":"Centre Armand-Frappier Sant\u00e9 Biotechnologie","ror":"https://ror.org/0562xaa66","country_code":"CA","type":"education","lineage":["https://openalex.org/I39481719","https://openalex.org/I4405287452","https://openalex.org/I49663120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marcel Desrosiers","raw_affiliation_strings":["Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I4405287452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110320442","display_name":"Ginette Mercier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287452","display_name":"Centre Armand-Frappier Sant\u00e9 Biotechnologie","ror":"https://ror.org/0562xaa66","country_code":"CA","type":"education","lineage":["https://openalex.org/I39481719","https://openalex.org/I4405287452","https://openalex.org/I49663120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ginette Mercier","raw_affiliation_strings":["Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I4405287452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110500279","display_name":"Jos\u00e9 Men\u00e9zes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Menezes","raw_affiliation_strings":["Laboratoire d'Immunovirologie, Universit\u00e9 de Montr\u00e9al et H\u00f4pital Sainte Justine, 3175, Chemin C\u00f4te Ste Catherine, Montr\u00e9al, Qu\u00e9bec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunovirologie, Universit\u00e9 de Montr\u00e9al et H\u00f4pital Sainte Justine, 3175, Chemin C\u00f4te Ste Catherine, Montr\u00e9al, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044933417","display_name":"Gilles Lamoureux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287452","display_name":"Centre Armand-Frappier Sant\u00e9 Biotechnologie","ror":"https://ror.org/0562xaa66","country_code":"CA","type":"education","lineage":["https://openalex.org/I39481719","https://openalex.org/I4405287452","https://openalex.org/I49663120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Gilles Lamoureux","raw_affiliation_strings":["Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I4405287452"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071364616","display_name":"Daniel Oth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287452","display_name":"Centre Armand-Frappier Sant\u00e9 Biotechnologie","ror":"https://ror.org/0562xaa66","country_code":"CA","type":"education","lineage":["https://openalex.org/I39481719","https://openalex.org/I4405287452","https://openalex.org/I49663120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Daniel Oth","raw_affiliation_strings":["Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche en Immunologie, Institut Armand-Frappier, C.P. 100, Laval-des-Rapides, Ville de Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I4405287452"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5087123692"],"corresponding_institution_ids":["https://openalex.org/I4405287452"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":null,"fwci":0.2816,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.60667252,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"1","first_page":"9","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tac-antigen","display_name":"Tac antigen","score":0.7900000214576721},{"id":"https://openalex.org/keywords/epstein-barr-virus","display_name":"Epstein-Barr virus","score":0.953000009059906},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.843999981880188},{"id":"https://openalex.org/keywords/lymphocyte-immortalization","display_name":"lymphocyte immortalization","score":0.8569999933242798}],"concepts":[{"id":"https://openalex.org/C2781375147","wikidata":"https://www.wikidata.org/wiki/Q6900","display_name":"Epstein\u2013Barr virus","level":3,"score":0.7993671894073486},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6529319882392883},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6273946762084961},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.5932390689849854},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5085338354110718},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4869314432144165},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3917842507362366},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3585329055786133},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.333281546831131}],"mesh":[{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002472","descriptor_name":"Cell Transformation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004854","descriptor_name":"Herpesvirus 4, Human","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011043","descriptor_name":"Pokeweed Mitogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011971","descriptor_name":"Receptors, Immunologic","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D015375","descriptor_name":"Receptors, Interleukin-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0165-2478(88)90062-4","doi":"https://doi.org/10.1016/0165-2478(88)90062-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-2478(88)90062-4","pdf_url":null,"source":{"id":"https://openalex.org/S71256826","display_name":"Immunology Letters","issn_l":"0165-2478","issn":["0165-2478","1879-0542"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunology Letters","raw_type":"journal-article"},{"id":"pmid:2837437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2837437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunology letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W133135585","https://openalex.org/W1560071173","https://openalex.org/W1634967536","https://openalex.org/W2020475082","https://openalex.org/W2025451399","https://openalex.org/W2067475593","https://openalex.org/W2080249344","https://openalex.org/W2115184661","https://openalex.org/W2123369755","https://openalex.org/W2145498103","https://openalex.org/W2163988580"],"related_works":["https://openalex.org/W1599249203","https://openalex.org/W2134555832","https://openalex.org/W2107313857","https://openalex.org/W2019574218","https://openalex.org/W1254101450","https://openalex.org/W2082678443","https://openalex.org/W2057154903","https://openalex.org/W1967776511","https://openalex.org/W4251704345","https://openalex.org/W2408544522"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}