{"id":"https://openalex.org/W1995587214","doi":"https://doi.org/10.1016/0165-1161(92)90039-o","title":"Structural basis of the in vivo induction of micronuclei","display_name":"Structural basis of the in vivo induction of micronuclei","publication_year":1992,"publication_date":"1992-10-01","ids":{"openalex":"https://openalex.org/W1995587214","doi":"https://doi.org/10.1016/0165-1161(92)90039-o","mag":"1995587214","pmid":"https://pubmed.ncbi.nlm.nih.gov/1383743"},"language":"en","primary_location":{"id":"doi:10.1016/0165-1161(92)90039-o","doi":"https://doi.org/10.1016/0165-1161(92)90039-o","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-1161(92)90039-o","pdf_url":null,"source":{"id":"https://openalex.org/S4210193812","display_name":"Mutation Research/Environmental Mutagenesis and Related Subjects","issn_l":"0165-1161","issn":["0165-1161","1878-7088"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Environmental Mutagenesis and Related Subjects","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113552615","display_name":"Wu-Lung Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wu-Lung Yang","raw_affiliation_strings":["Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15261","Department of Environmental and Occupational Health Graduate School of Public Health University of Pittsburgh  Pittsburgh PA 15261 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Environmental and Occupational Health Graduate School of Public Health University of Pittsburgh  Pittsburgh PA 15261 USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109951465","display_name":"Gilles Klopman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gilles Klopman","raw_affiliation_strings":["Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073709590","display_name":"Herbert S. Rosenkranz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Herbert S. Rosenkranz","raw_affiliation_strings":["Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073709590"],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":null,"apc_paid":null,"fwci":1.2564,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.78121071,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"272","issue":"2","first_page":"111","last_page":"124"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/micronuclei","display_name":"micronuclei","score":0.8420000076293945},{"id":"https://openalex.org/keywords/in-vivo-induction","display_name":"in vivo induction","score":0.6539999842643738},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.8399999737739563},{"id":"https://openalex.org/keywords/structural-factors","display_name":"structural factors","score":0.7870000004768372},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":0.621999979019165},{"id":"https://openalex.org/keywords/mutagenicity-prediction","display_name":"mutagenicity prediction","score":0.6970000267028809},{"id":"https://openalex.org/keywords/molecular-structure","display_name":"molecular structure","score":0.4259999990463257}],"concepts":[{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.897716760635376},{"id":"https://openalex.org/C12426560","wikidata":"https://www.wikidata.org/wiki/Q189569","display_name":"Basis (linear algebra)","level":2,"score":0.6475729942321777},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5916513204574585},{"id":"https://openalex.org/C160798450","wikidata":"https://www.wikidata.org/wiki/Q4230870","display_name":"Concordance","level":2,"score":0.586500883102417},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41573670506477356},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4105822443962097},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3499923348426819},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2937434911727905},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2008642852306366},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.07881197333335876},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D009153","descriptor_name":"Mutagens","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D009153","descriptor_name":"Mutagens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015162","descriptor_name":"Micronucleus Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0165-1161(92)90039-o","doi":"https://doi.org/10.1016/0165-1161(92)90039-o","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-1161(92)90039-o","pdf_url":null,"source":{"id":"https://openalex.org/S4210193812","display_name":"Mutation Research/Environmental Mutagenesis and Related Subjects","issn_l":"0165-1161","issn":["0165-1161","1878-7088"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Environmental Mutagenesis and Related Subjects","raw_type":"journal-article"},{"id":"pmid:1383743","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1383743","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.46810001134872437,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3663519407","display_name":null,"funder_award_id":"(ES04659)","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G7635916638","display_name":"QUANTIFYING NITROARENE GENOTOXICITY IN COMPLEX MIXTURES","funder_award_id":"R01ES004659","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W205248819","https://openalex.org/W1983338587","https://openalex.org/W1990494717","https://openalex.org/W1995960307","https://openalex.org/W2008764714","https://openalex.org/W2016509315","https://openalex.org/W2023297283","https://openalex.org/W2036899644","https://openalex.org/W2039292327","https://openalex.org/W2043453252","https://openalex.org/W2054370527","https://openalex.org/W2063431869","https://openalex.org/W2066936755","https://openalex.org/W2099259982","https://openalex.org/W2118633304","https://openalex.org/W2126136513","https://openalex.org/W2149352233"],"related_works":["https://openalex.org/W2039292327","https://openalex.org/W2334802700","https://openalex.org/W1991871732","https://openalex.org/W2352939643","https://openalex.org/W1988892680","https://openalex.org/W2058969453","https://openalex.org/W2116483187","https://openalex.org/W2023459820","https://openalex.org/W922791219","https://openalex.org/W4298269373"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}