{"id":"https://openalex.org/W1995508408","doi":"https://doi.org/10.1016/0020-711x(87)90137-6","title":"Effects of superoxide generated in vitro on glucuronidation of benzo[a]pyrene metabolites by mouse liver microsomes","display_name":"Effects of superoxide generated in vitro on glucuronidation of benzo[a]pyrene metabolites by mouse liver microsomes","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W1995508408","doi":"https://doi.org/10.1016/0020-711x(87)90137-6","mag":"1995508408","pmid":"https://pubmed.ncbi.nlm.nih.gov/3038635"},"language":"en","primary_location":{"id":"doi:10.1016/0020-711x(87)90137-6","doi":"https://doi.org/10.1016/0020-711x(87)90137-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0020-711x(87)90137-6","pdf_url":null,"source":{"id":"https://openalex.org/S116532113","display_name":"International Journal of Biochemistry","issn_l":"0020-711X","issn":["0020-711X","1878-6014"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016968685","display_name":"Janusz Z. Byczkowski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janusz Z. Byczkowski","raw_affiliation_strings":["Grace Cancer Drug Center, Roswell Park Memorial Institute, 666 Elm Street, Buffalo, NY 14263, U.S.A. [Tel. (716) 845-8738]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grace Cancer Drug Center, Roswell Park Memorial Institute, 666 Elm Street, Buffalo, NY 14263, U.S.A. [Tel. (716) 845-8738]","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113525672","display_name":"Teresa Gessner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teresa Gessner","raw_affiliation_strings":["Grace Cancer Drug Center, Roswell Park Memorial Institute, 666 Elm Street, Buffalo, NY 14263, U.S.A. [Tel. (716) 845-8738]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grace Cancer Drug Center, Roswell Park Memorial Institute, 666 Elm Street, Buffalo, NY 14263, U.S.A. [Tel. (716) 845-8738]","institution_ids":["https://openalex.org/I1292894508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1292894508"],"apc_list":null,"apc_paid":null,"fwci":2.9748,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.91205752,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"19","issue":"6","first_page":"531","last_page":"537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzo-a-pyrene","display_name":"benzo[a]pyrene","score":0.9909999966621399},{"id":"https://openalex.org/keywords/glucuronidation","display_name":"glucuronidation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/superoxide-radicals","display_name":"superoxide","score":0.8309999704360962},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.984000027179718},{"id":"https://openalex.org/keywords/udp-glucuronosyltransferase","display_name":"UDP-glucuronosyltransferase","score":0.9490000009536743},{"id":"https://openalex.org/keywords/udpga","display_name":"UDPGA","score":0.7409999966621399},{"id":"https://openalex.org/keywords/benzo-a-pyrene-metabolites","display_name":"benzo[a]pyrene metabolites","score":0.8529999852180481},{"id":"https://openalex.org/keywords/hydroxylated-metabolites","display_name":"hydroxylated metabolites","score":0.7049999833106995},{"id":"https://openalex.org/keywords/macromolecule-binding","display_name":"macromolecule binding","score":0.7120000123977661},{"id":"https://openalex.org/keywords/mouse-liver-microsomes","display_name":"mouse liver microsomes","score":0.8519999980926514},{"id":"https://openalex.org/keywords/polycyclic-aromatic-hydrocarbons","display_name":"polycyclic aromatic hydrocarbons","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C2779907587","wikidata":"https://www.wikidata.org/wiki/Q14901439","display_name":"Glucuronidation","level":4,"score":0.9170268774032593},{"id":"https://openalex.org/C87644729","wikidata":"https://www.wikidata.org/wiki/Q547502","display_name":"Microsome","level":3,"score":0.8864231109619141},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7740060091018677},{"id":"https://openalex.org/C2776524530","wikidata":"https://www.wikidata.org/wiki/Q4119721","display_name":"Microsoma","level":4,"score":0.6688557267189026},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6671815514564514},{"id":"https://openalex.org/C2777538855","wikidata":"https://www.wikidata.org/wiki/Q306051","display_name":"Benzo(a)pyrene","level":3,"score":0.6254715919494629},{"id":"https://openalex.org/C2778951431","wikidata":"https://www.wikidata.org/wiki/Q415723","display_name":"Pyrene","level":2,"score":0.5905933380126953},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.5533492565155029},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.49517908692359924},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.42340725660324097},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.4130040407180786},{"id":"https://openalex.org/C114246631","wikidata":"https://www.wikidata.org/wiki/Q187661","display_name":"Carcinogen","level":2,"score":0.24148118495941162},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.22773104906082153},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.05732271075248718}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001564","descriptor_name":"Benzo(a)pyrene","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008054","descriptor_name":"Lipid Peroxides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008811","descriptor_name":"Mice, Inbred DBA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008862","descriptor_name":"Microsomes, Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008862","descriptor_name":"Microsomes, Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D013481","descriptor_name":"Superoxides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014453","descriptor_name":"Glucuronosyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014535","descriptor_name":"Uridine Diphosphate Glucuronic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0020-711x(87)90137-6","doi":"https://doi.org/10.1016/0020-711x(87)90137-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0020-711x(87)90137-6","pdf_url":null,"source":{"id":"https://openalex.org/S116532113","display_name":"International Journal of Biochemistry","issn_l":"0020-711X","issn":["0020-711X","1878-6014"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:3038635","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3038635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International journal of biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.46810001134872437}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8668415893","display_name":"CONJUGATIONS AND CARCINOGEN METABOLISM","funder_award_id":"R01CA024127","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W199160386","https://openalex.org/W587932429","https://openalex.org/W1481125693","https://openalex.org/W1481950549","https://openalex.org/W1497802086","https://openalex.org/W1510393228","https://openalex.org/W1554848998","https://openalex.org/W1559871277","https://openalex.org/W1775749144","https://openalex.org/W1881840670","https://openalex.org/W1966739277","https://openalex.org/W1970793576","https://openalex.org/W1973184890","https://openalex.org/W1979899469","https://openalex.org/W1993693860","https://openalex.org/W2002438453","https://openalex.org/W2003614934","https://openalex.org/W2012005671","https://openalex.org/W2028231838","https://openalex.org/W2032011248","https://openalex.org/W2033578624","https://openalex.org/W2034151608","https://openalex.org/W2042000465","https://openalex.org/W2054031732","https://openalex.org/W2054973025","https://openalex.org/W2060915947","https://openalex.org/W2064449868","https://openalex.org/W2071989101","https://openalex.org/W2075425793","https://openalex.org/W2084718298","https://openalex.org/W2177185807","https://openalex.org/W2397948379","https://openalex.org/W6633338681"],"related_works":["https://openalex.org/W199160386","https://openalex.org/W1554848998","https://openalex.org/W1970793576","https://openalex.org/W2064449868","https://openalex.org/W2012876041","https://openalex.org/W2037288002","https://openalex.org/W2081199754","https://openalex.org/W1984481747","https://openalex.org/W2094621484","https://openalex.org/W2071989101"],"abstract_inverted_index":null,"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}