{"id":"https://openalex.org/W1995401122","doi":"https://doi.org/10.1371/journal.pone.0018642","title":"Association of HIV Diversity and Survival in HIV-Infected Ugandan Infants","display_name":"Association of HIV Diversity and Survival in HIV-Infected Ugandan Infants","publication_year":2011,"publication_date":"2011-04-14","ids":{"openalex":"https://openalex.org/W1995401122","doi":"https://doi.org/10.1371/journal.pone.0018642","mag":"1995401122","pmid":"https://pubmed.ncbi.nlm.nih.gov/21533179","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3077388"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0018642","doi":"https://doi.org/10.1371/journal.pone.0018642","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0018642","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0018642&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0018642&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049719522","display_name":"Maria M. James","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria M. James","raw_affiliation_strings":["Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100435759","display_name":"Lei Wang","orcid":"https://orcid.org/0000-0001-6915-2713","observed_orcids":["https://orcid.org/0000-0001-6915-2713","https://orcid.org/0000-0002-4683-2967"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lei Wang","raw_affiliation_strings":["Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057946567","display_name":"Philippa Musoke","orcid":"https://orcid.org/0000-0002-1875-202X","observed_orcids":["https://orcid.org/0000-0002-1875-202X"]},"institutions":[{"id":"https://openalex.org/I4210121676","display_name":"MUJHU Research Collaboration","ror":"https://ror.org/02ee2kk58","country_code":"UG","type":"facility","lineage":["https://openalex.org/I4210121676"]},{"id":"https://openalex.org/I72227227","display_name":"Makerere University","ror":"https://ror.org/03dmz0111","country_code":"UG","type":"education","lineage":["https://openalex.org/I72227227"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Philippa Musoke","raw_affiliation_strings":["Makerere University School of Medicine, Kampala, Uganda","Makerere University-Johns Hopkins University Research Collaboration (MU-JHU), Baltimore, Maryland, United States of America, and Kampala, Uganda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Makerere University School of Medicine, Kampala, Uganda","institution_ids":["https://openalex.org/I72227227"]},{"raw_affiliation_string":"Makerere University-Johns Hopkins University Research Collaboration (MU-JHU), Baltimore, Maryland, United States of America, and Kampala, Uganda","institution_ids":["https://openalex.org/I4210121676"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065911353","display_name":"Deborah J Donnell","orcid":"https://orcid.org/0000-0002-0587-7480","observed_orcids":["https://orcid.org/0000-0002-0587-7480"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah Donnell","raw_affiliation_strings":["Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017238174","display_name":"Jessica M. Fogel","orcid":"https://orcid.org/0000-0003-3143-9000","observed_orcids":["https://orcid.org/0000-0003-3143-9000"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica Fogel","raw_affiliation_strings":["Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062868909","display_name":"William I. Towler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William I. Towler","raw_affiliation_strings":["Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035082849","display_name":"Leila Khaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leila Khaki","raw_affiliation_strings":["Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110278435","display_name":"Clemensia Nakabiito","orcid":"https://orcid.org/0009-0005-8814-0810","observed_orcids":["https://orcid.org/0009-0005-8814-0810"]},"institutions":[{"id":"https://openalex.org/I4210121676","display_name":"MUJHU Research Collaboration","ror":"https://ror.org/02ee2kk58","country_code":"UG","type":"facility","lineage":["https://openalex.org/I4210121676"]},{"id":"https://openalex.org/I72227227","display_name":"Makerere University","ror":"https://ror.org/03dmz0111","country_code":"UG","type":"education","lineage":["https://openalex.org/I72227227"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Clemensia Nakabiito","raw_affiliation_strings":["Makerere University School of Medicine, Kampala, Uganda","Makerere University-Johns Hopkins University Research Collaboration (MU-JHU), Baltimore, Maryland, United States of America, and Kampala, Uganda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Makerere University School of Medicine, Kampala, Uganda","institution_ids":["https://openalex.org/I72227227"]},{"raw_affiliation_string":"Makerere University-Johns Hopkins University Research Collaboration (MU-JHU), Baltimore, Maryland, United States of America, and Kampala, Uganda","institution_ids":["https://openalex.org/I4210121676"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000033990","display_name":"J. Brooks Jackson","orcid":"https://orcid.org/0000-0001-9458-135X","observed_orcids":["https://orcid.org/0000-0001-9458-135X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Brooks Jackson","raw_affiliation_strings":["Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081294489","display_name":"Susan H. Eshleman","orcid":"https://orcid.org/0000-0002-4587-791X","observed_orcids":["https://orcid.org/0000-0002-4587-791X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Susan H. Eshleman","raw_affiliation_strings":["Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5081294489"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":1.8948,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.84372331,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"6","issue":"4","first_page":"e18642","last_page":"e18642"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-genetic-diversity","display_name":"HIV genetic diversity","score":0.8410000205039978},{"id":"https://openalex.org/keywords/hiv-infected-infants","display_name":"HIV-infected infants","score":0.8949999809265137},{"id":"https://openalex.org/keywords/infant-survival","display_name":"infant survival","score":0.5730000138282776},{"id":"https://openalex.org/keywords/mortality-risk","display_name":"mortality risk","score":0.7409999966621399},{"id":"https://openalex.org/keywords/gag-gene","display_name":"gag gene","score":0.824999988079071},{"id":"https://openalex.org/keywords/pol-gene","display_name":"pol gene","score":0.9980000257492065},{"id":"https://openalex.org/keywords/high-resolution-melting-analysis","display_name":"high-resolution melting analysis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.3449999988079071}],"concepts":[{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.5859403610229492},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5452703237533569},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5292807221412659},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49511757493019104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4617815613746643},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.4532441198825836},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4501689076423645},{"id":"https://openalex.org/C2781316041","wikidata":"https://www.wikidata.org/wiki/Q1230584","display_name":"Diversity (politics)","level":2,"score":0.4156266748905182},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36066848039627075},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3375105559825897},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.2562863230705261},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006678","descriptor_name":"HIV","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014454","descriptor_name":"Uganda","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pone.0018642","doi":"https://doi.org/10.1371/journal.pone.0018642","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0018642","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0018642&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2092347","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3077388","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3077388","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3077388","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:21533179","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21533179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.291.8437","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.291.8437","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/41/11/PLoS_One_2011_Apr_14_6(4)_e18642.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:faa28ffe93bc4c5bb6825eff1e5515fd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/faa28ffe93bc4c5bb6825eff1e5515fd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 6, Iss 4, p e18642 (2011)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/137525","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Association_of_HIV_Diversity_and_Survival_in_HIV_Infected_Ugandan_Infants/137525","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0018642","doi":"https://doi.org/10.1371/journal.pone.0018642","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0018642","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0018642&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7699999809265137,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1092790396","display_name":"STATISTICAL &CLINICAL COORDINATING CENTER (SC)","funder_award_id":"n01ai045200-020","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1182978172","display_name":null,"funder_award_id":"N0I-AI-035173-417","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G1216628595","display_name":"Leadership for HIV/AIDS Clinical Trials Networks; HIV Prevention Trials Network","funder_award_id":"U01AI068617","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2358511323","display_name":null,"funder_award_id":"N01 AI045200","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4748042802","display_name":null,"funder_award_id":"R01-AI087139","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5768112423","display_name":null,"funder_award_id":"AI068613","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G604624914","display_name":"INTNL.VACC.EFFICACY TRIALS MASTER CONTRACT (IMC)","funder_award_id":"n01ai035173-037","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6086077386","display_name":"International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group","funder_award_id":"U01AI068632","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G622809771","display_name":null,"funder_award_id":"AI068632","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6600055024","display_name":"HIV Prevention Trials Network: Network Laboratory","funder_award_id":"U01AI068613","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7742187551","display_name":null,"funder_award_id":"AI068632","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000014638","display_name":null,"funder_award_id":"AI068632","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G982464176","display_name":null,"funder_award_id":"N01-AI-035173","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G995443052","display_name":"Impact of maternal HAART on HIV-infected breastfeeding infants: Malawi","funder_award_id":"5r01ai087139-04","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320317807","display_name":"International Maternal Pediatric Adolescent AIDS Clinical Trials Network","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1995401122.pdf","grobid_xml":"https://content.openalex.org/works/W1995401122.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W1532718280","https://openalex.org/W1539316786","https://openalex.org/W1789164989","https://openalex.org/W1838993423","https://openalex.org/W1963704583","https://openalex.org/W1971278668","https://openalex.org/W1986371227","https://openalex.org/W1987037885","https://openalex.org/W1990105675","https://openalex.org/W1991526126","https://openalex.org/W1992194744","https://openalex.org/W1992891916","https://openalex.org/W2002574877","https://openalex.org/W2013251170","https://openalex.org/W2025279400","https://openalex.org/W2031839738","https://openalex.org/W2035259223","https://openalex.org/W2038405004","https://openalex.org/W2056512147","https://openalex.org/W2066132770","https://openalex.org/W2066232369","https://openalex.org/W2072918223","https://openalex.org/W2086104438","https://openalex.org/W2086931436","https://openalex.org/W2096244211","https://openalex.org/W2104634067","https://openalex.org/W2106688939","https://openalex.org/W2110278919","https://openalex.org/W2110628058","https://openalex.org/W2111550532","https://openalex.org/W2112475246","https://openalex.org/W2115981562","https://openalex.org/W2116794821","https://openalex.org/W2120110886","https://openalex.org/W2122986037","https://openalex.org/W2126515754","https://openalex.org/W2127146638","https://openalex.org/W2130977216","https://openalex.org/W2131328336","https://openalex.org/W2144324254","https://openalex.org/W2149629952","https://openalex.org/W2151235890","https://openalex.org/W2155477016","https://openalex.org/W2162727140","https://openalex.org/W2170830827","https://openalex.org/W2170947401","https://openalex.org/W2312499014","https://openalex.org/W2320433970","https://openalex.org/W2616334093","https://openalex.org/W6675984815"],"related_works":["https://openalex.org/W2002103344","https://openalex.org/W7098250715","https://openalex.org/W2060526788","https://openalex.org/W7099193020","https://openalex.org/W2109549126","https://openalex.org/W2254628938","https://openalex.org/W2560485652","https://openalex.org/W4389990396","https://openalex.org/W4298358656","https://openalex.org/W2122944844"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,103],"level":[2,37],"of":[3,15,25,38,89,166,179,184,194,203,255,264,269],"viral":[4,21,26,39,48],"diversity":[5,40,74,83,110,226,248],"in":[6,35,41,47,75,111,114,124,132,227,249],"an":[7,176,213],"HIV-infected":[8,42,98],"individual":[9],"can":[10],"change":[11],"during":[12,20],"the":[13,36,80,115,125,170,234],"course":[14],"HIV":[16,59,73,228,247],"infection,":[17],"reflecting":[18],"mutagenesis":[19],"replication":[22],"and":[23,30,78,84,119,121,218,221,230,242],"selection":[24],"variants":[27],"by":[28,181,266],"immune":[29,50],"other":[31,53,219],"selective":[32],"pressures.":[33],"Differences":[34],"infants":[43,77,99],"may":[44,56],"reflect":[45],"differences":[46],"dynamics,":[49],"responses,":[51],"or":[52],"factors":[54],"that":[55],"also":[57],"influence":[58],"disease":[60],"progression.":[61],"We":[62,209],"used":[63,107],"a":[64,260],"novel":[65],"high":[66],"resolution":[67],"melting":[68],"(HRM)":[69],"assay":[70,105,236],"to":[71,108,142],"measure":[72,109],"Ugandan":[76],"examined":[79],"relationship":[81],"between":[82,215],"survival":[85],"through":[86],"5":[87,182,267],"years":[88,183,268],"age.":[90,270],"METHODS:":[91],"Plasma":[92],"samples":[93],"were":[94,173],"obtained":[95],"from":[96,139],"31":[97],"(HIVNET":[100],"012":[101],"trial).":[102],"HRM":[104,130,161,216,235],"was":[106,237,257],"two":[112,195],"regions":[113,135,251],"gag":[116,229],"gene":[117,127],"(Gag1":[118],"Gag2)":[120],"one":[122],"region":[123],"pol":[126,231],"(Pol).":[128],"RESULTS:":[129],"scores":[131,162,217],"all":[133],"three":[134,204],"increased":[136,177,243,262],"with":[137,175,259],"age":[138,167,185,256],"6-8":[140,164,253],"weeks":[141,165,254],"12-18":[143],"months":[144],"(for":[145,186],"Gag1:":[146],"P":[147,152,157,188,197,206],"=":[148,153,158,189,198,207],"0.005;":[149,190],"for":[150,155,191,200],"Gag2:":[151],"0.006;":[154],"Pol:":[156,187],"0.016).":[159],"Higher":[160,246],"at":[163,252],"(scores":[168],"above":[169],"75(th)":[171],"percentile)":[172],"associated":[174,258],"risk":[178,263],"death":[180,265],"Gag1/Gag2":[192],"(mean":[193,202],"scores):":[196,205],"0.003;":[199],"Gag1/Gag2/Pol":[201],"0.002).":[208],"did":[210],"not":[211],"find":[212],"association":[214],"clinical":[220],"laboratory":[222],"variables.":[223],"CONCLUSIONS:":[224],"Genetic":[225],"measured":[232],"using":[233],"typically":[238],"low":[239],"near":[240],"birth":[241],"over":[244],"time.":[245],"these":[250],"significantly":[261]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
