{"id":"https://openalex.org/W1995251646","doi":"https://doi.org/10.1016/j.bbagrm.2014.07.013","title":"A key role of the mitochondrial citrate carrier (SLC25A1) in TNF\u03b1- and IFN\u03b3-triggered inflammation","display_name":"A key role of the mitochondrial citrate carrier (SLC25A1) in TNF\u03b1- and IFN\u03b3-triggered inflammation","publication_year":2014,"publication_date":"2014-07-26","ids":{"openalex":"https://openalex.org/W1995251646","doi":"https://doi.org/10.1016/j.bbagrm.2014.07.013","mag":"1995251646","pmid":"https://pubmed.ncbi.nlm.nih.gov/25072865","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346166"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbagrm.2014.07.013","doi":"https://doi.org/10.1016/j.bbagrm.2014.07.013","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbagrm.2014.07.013","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1874939914002016","source":{"id":"https://openalex.org/S4210203689","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","issn_l":"1874-9399","issn":["1874-9399","1876-4320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1995251646"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S1874939914002016","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067854637","display_name":"Vittoria Infantino","orcid":"https://orcid.org/0000-0002-8509-5218","observed_orcids":["https://orcid.org/0000-0002-8509-5218"]},"institutions":[{"id":"https://openalex.org/I20272500","display_name":"University of Basilicata","ror":"https://ror.org/03tc05689","country_code":"IT","type":"education","lineage":["https://openalex.org/I20272500"]},{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vittoria Infantino","raw_affiliation_strings":["Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy","Department of Science, University of Basilicata, via N. Sauro 85, 85100 Potenza, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]},{"raw_affiliation_string":"Department of Science, University of Basilicata, via N. Sauro 85, 85100 Potenza, Italy","institution_ids":["https://openalex.org/I20272500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012198242","display_name":"Vito Iacobazzi","orcid":"https://orcid.org/0000-0002-0470-2056","observed_orcids":["https://orcid.org/0000-0002-0470-2056"]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vito Iacobazzi","raw_affiliation_strings":["Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033985207","display_name":"Alessio Menga","orcid":"https://orcid.org/0000-0002-2827-5298","observed_orcids":["https://orcid.org/0000-0002-2827-5298"]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessio Menga","raw_affiliation_strings":["Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072563828","display_name":"Maria Laura Avantaggiati","orcid":"https://orcid.org/0000-0001-8361-3440","observed_orcids":["https://orcid.org/0000-0001-8361-3440"]},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I4390039356","display_name":"Georgetown Lombardi Comprehensive Cancer Center","ror":"https://ror.org/035zrb927","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I184565670","https://openalex.org/I4390039356"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Laura Avantaggiati","raw_affiliation_strings":["Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I4390039356"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008679103","display_name":"Ferdinando Palmieri","orcid":"https://orcid.org/0000-0002-4672-291X","observed_orcids":["https://orcid.org/0000-0002-4672-291X"]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Ferdinando Palmieri","raw_affiliation_strings":["Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona 4, 70125 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5008679103"],"corresponding_institution_ids":["https://openalex.org/I5561750"],"apc_list":{"value":3840,"currency":"USD","value_usd":3840},"apc_paid":null,"fwci":2.7072,"has_fulltext":true,"cited_by_count":201,"citation_normalized_percentile":{"value":0.91609685,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"1839","issue":"11","first_page":"1217","last_page":"1225"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.5264000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.5264000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.08529999852180481,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.05209999904036522,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-citrate-carrier","display_name":"mitochondrial citrate carrier","score":0.9160000085830688},{"id":"https://openalex.org/keywords/slc25a1","display_name":"SLC25A1","score":1.0},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.6050000190734863},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.871999979019165},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8679999709129333},{"id":"https://openalex.org/keywords/nf-kappab","display_name":"NF-\u03baB","score":0.9070000052452087},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9139999747276306},{"id":"https://openalex.org/keywords/prostaglandins","display_name":"prostaglandins","score":0.9679999947547913},{"id":"https://openalex.org/keywords/acetyl-coa","display_name":"acetyl-CoA","score":0.9470000267028809},{"id":"https://openalex.org/keywords/mitochondrial-bioenergetics","display_name":"mitochondrial bioenergetics","score":0.7649999856948853},{"id":"https://openalex.org/keywords/cytokine-signaling","display_name":"cytokine signaling","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.77010178565979},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6477103233337402},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.618451714515686},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5526960492134094},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.5383409857749939},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.5110565423965454},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4359170198440552},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.43447983264923096},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4118626117706299},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3918876647949219},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2580142319202423},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2349504828453064},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1486874222755432},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1305050551891327}],"mesh":[{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020298","descriptor_name":"U937 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D027321","descriptor_name":"Anion Transport Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D027321","descriptor_name":"Anion Transport Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D027361","descriptor_name":"Organic Anion Transporters","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1016/j.bbagrm.2014.07.013","doi":"https://doi.org/10.1016/j.bbagrm.2014.07.013","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbagrm.2014.07.013","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1874939914002016","source":{"id":"https://openalex.org/S4210203689","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","issn_l":"1874-9399","issn":["1874-9399","1876-4320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","raw_type":"journal-article"},{"id":"pmid:25072865","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25072865","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3313339","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346166","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4346166","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4346166/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochim Biophys Acta","raw_type":"Text"},{"id":"pmh:oai:iris.unito.it:2318/1869078","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2318/1869078","pdf_url":"https://iris.unito.it/bitstream/2318/1869078/1/1-s2.0-S1874939914002016-main%281%29.pdf","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unibas.it:11563/109493","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11563/109493","pdf_url":null,"source":{"id":"https://openalex.org/S4377196360","display_name":"CINECA IRIS Institutional Research Information System (University of Basilicata)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I20272500","host_organization_name":"University of Basilicata","host_organization_lineage":["https://openalex.org/I20272500"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ricerca.uniba.it:11586/66707","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11586/66707","pdf_url":null,"source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.bbagrm.2014.07.013","doi":"https://doi.org/10.1016/j.bbagrm.2014.07.013","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbagrm.2014.07.013","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1874939914002016","source":{"id":"https://openalex.org/S4210203689","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","issn_l":"1874-9399","issn":["1874-9399","1876-4320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3411524994","display_name":"Progettazione e sintesi stereoselettiva di composti attivi verso bersagli proteici coinvolti in patologie virali e tumorali","funder_award_id":"20109Z2XRJ","funder_id":"https://openalex.org/F4320321873","funder_display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca"},{"id":"https://openalex.org/G5193547763","display_name":"Georgetown-Howard Universities Center for Clinical and Translational Science (GHU","funder_award_id":"UL1TR000101","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5707136246","display_name":null,"funder_award_id":"RBRN07BMCT_009","funder_id":"https://openalex.org/F4320331528","funder_display_name":"Ministero dell'Universit\u00e0 e della Ricerca"},{"id":"https://openalex.org/G7031305919","display_name":null,"funder_award_id":"20109Z2XRJ 009","funder_id":"https://openalex.org/F4320321873","funder_display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca"},{"id":"https://openalex.org/G9000862544","display_name":"Georgetown University Lombardi Comprehensive Cancer Center Support Grant","funder_award_id":"P30CA051008","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320321873","display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","ror":"https://ror.org/0166hxq48"},{"id":"https://openalex.org/F4320331528","display_name":"Ministero dell'Universit\u00e0 e della Ricerca","ror":"https://ror.org/0341vw408"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1995251646.pdf","grobid_xml":"https://content.openalex.org/works/W1995251646.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W160934395","https://openalex.org/W1491060698","https://openalex.org/W1967444052","https://openalex.org/W1970822787","https://openalex.org/W1977885765","https://openalex.org/W1978076094","https://openalex.org/W1988210099","https://openalex.org/W1989162487","https://openalex.org/W2015687268","https://openalex.org/W2016430217","https://openalex.org/W2020138750","https://openalex.org/W2022720370","https://openalex.org/W2024021877","https://openalex.org/W2024988671","https://openalex.org/W2031084334","https://openalex.org/W2031609440","https://openalex.org/W2032773079","https://openalex.org/W2033684021","https://openalex.org/W2046529467","https://openalex.org/W2049044905","https://openalex.org/W2053889157","https://openalex.org/W2054800464","https://openalex.org/W2069775190","https://openalex.org/W2071420454","https://openalex.org/W2074991244","https://openalex.org/W2082146979","https://openalex.org/W2090126290","https://openalex.org/W2092961032","https://openalex.org/W2101535451","https://openalex.org/W2101574511","https://openalex.org/W2103567384","https://openalex.org/W2105896882","https://openalex.org/W2126151066","https://openalex.org/W2133132450","https://openalex.org/W2138709778","https://openalex.org/W2144575277","https://openalex.org/W2145158854","https://openalex.org/W2146738245","https://openalex.org/W2155913937","https://openalex.org/W2157890202","https://openalex.org/W2157936931","https://openalex.org/W2160284636","https://openalex.org/W2167017590","https://openalex.org/W2398571569","https://openalex.org/W2418466961","https://openalex.org/W4242182607","https://openalex.org/W4252146505","https://openalex.org/W6717088190"],"related_works":["https://openalex.org/W2160284636","https://openalex.org/W2530987987","https://openalex.org/W2800650242","https://openalex.org/W3122767802","https://openalex.org/W1884221296","https://openalex.org/W7064857068","https://openalex.org/W4313383857","https://openalex.org/W2090126290","https://openalex.org/W3209395172","https://openalex.org/W4416842949"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":22},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":25},{"year":2020,"cited_by_count":25},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":8}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}