{"id":"https://openalex.org/W1995201499","doi":"https://doi.org/10.1038/205980a0","title":"Recovery from the \u2018Lethal\u2019 Effects of Cross-Linking Alkylation","display_name":"Recovery from the \u2018Lethal\u2019 Effects of Cross-Linking Alkylation","publication_year":1965,"publication_date":"1965-03-01","ids":{"openalex":"https://openalex.org/W1995201499","doi":"https://doi.org/10.1038/205980a0","mag":"1995201499","pmid":"https://pubmed.ncbi.nlm.nih.gov/14302882"},"language":"en","primary_location":{"id":"doi:10.1038/205980a0","doi":"https://doi.org/10.1038/205980a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/205980a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064960836","display_name":"Anthony H. Loveless","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. LOVELESS","raw_affiliation_strings":["Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3","Institute of Cancer Research, Royal Cancer Hospital, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"Institute of Cancer Research, Royal Cancer Hospital, London","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110059446","display_name":"Judy Cook","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"JUDY COOK","raw_affiliation_strings":["Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3","Institute of Cancer Research, Royal Cancer Hospital, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"Institute of Cancer Research, Royal Cancer Hospital, London","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034342854","display_name":"PAMELA WHEATLEY","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"PAMELA WHEATLEY","raw_affiliation_strings":["Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3","Institute of Cancer Research, Royal Cancer Hospital, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"Institute of Cancer Research, Royal Cancer Hospital, London","institution_ids":["https://openalex.org/I142947616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I142947616"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":3.6783,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.93284337,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"205","issue":"4975","first_page":"980","last_page":"983"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.44850000739097595,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.44850000739097595,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.382099986076355,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.013500000350177288,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-alkylation","display_name":"DNA alkylation","score":0.5960000157356262},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.7820000052452087},{"id":"https://openalex.org/keywords/dna-repair-enzymes","display_name":"DNA repair enzymes","score":0.3930000066757202},{"id":"https://openalex.org/keywords/alkyltransferase","display_name":"alkyltransferase","score":0.6169999837875366},{"id":"https://openalex.org/keywords/dna-cross-linking","display_name":"DNA cross-linking","score":0.33399999141693115}],"concepts":[{"id":"https://openalex.org/C164361826","wikidata":"https://www.wikidata.org/wiki/Q177604","display_name":"Alkylation","level":3,"score":0.6215581893920898},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4930398166179657},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21328645944595337},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000477","descriptor_name":"Alkylating Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000478","descriptor_name":"Alkylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008660","descriptor_name":"Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009150","descriptor_name":"Mustard Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010600","descriptor_name":"Pharmacology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010829","descriptor_name":"Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1038/205980a0","doi":"https://doi.org/10.1038/205980a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/205980a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:14302882","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14302882","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W85996255","https://openalex.org/W1259363667","https://openalex.org/W1966240333","https://openalex.org/W1966892104","https://openalex.org/W1988284081","https://openalex.org/W1990048057","https://openalex.org/W2023990700","https://openalex.org/W2029014497","https://openalex.org/W2038531066","https://openalex.org/W2039025555","https://openalex.org/W2074102392","https://openalex.org/W2080400554","https://openalex.org/W2085653233","https://openalex.org/W2410456531","https://openalex.org/W2415446846"],"related_works":["https://openalex.org/W4238384382","https://openalex.org/W7124515802","https://openalex.org/W2051064971","https://openalex.org/W1492048477","https://openalex.org/W130247392","https://openalex.org/W2068819259","https://openalex.org/W2253734654","https://openalex.org/W2084407647","https://openalex.org/W2034255578","https://openalex.org/W1584903666"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}