{"id":"https://openalex.org/W1995178297","doi":"https://doi.org/10.1046/j.1365-2036.2001.00997.x","title":"Abnormal bone turnover in long\u2010standing Crohn\u2019s disease in remission","display_name":"Abnormal bone turnover in long\u2010standing Crohn\u2019s disease in remission","publication_year":2001,"publication_date":"2001-06-12","ids":{"openalex":"https://openalex.org/W1995178297","doi":"https://doi.org/10.1046/j.1365-2036.2001.00997.x","mag":"1995178297","pmid":"https://pubmed.ncbi.nlm.nih.gov/11380316"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2036.2001.00997.x","doi":"https://doi.org/10.1046/j.1365-2036.2001.00997.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2036.2001.00997.x","pdf_url":null,"source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology &amp; Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://cris.maastrichtuniversity.nl/en/publications/aa53423e-5b3f-4acc-8d2e-7dfb34309229","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025611672","display_name":"Erik J. Schoon","orcid":"https://orcid.org/0000-0003-4515-1235","observed_orcids":["https://orcid.org/0000-0003-4515-1235"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"E. J. Schoon","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, University Hospital Maastricht, Maastricht, The Netherlands. ESCH@sint.azm.nl","Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital Maastricht, Maastricht, The Netherlands. ESCH@sint.azm.nl","institution_ids":["https://openalex.org/I2800191616"]},{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015831220","display_name":"B. G. Geerling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"B. G. Geerling","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005720282","display_name":"Ivo M. A. van Dooren","orcid":"https://orcid.org/0000-0002-5520-0232","observed_orcids":["https://orcid.org/0000-0002-5520-0232"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"I. M. A. Van Dooren","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070811893","display_name":"Leon J. Schurgers","orcid":"https://orcid.org/0000-0001-7867-6957","observed_orcids":["https://orcid.org/0000-0001-7867-6957"]},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"L. J. Schurgers","raw_affiliation_strings":["Department of Biochemistry, University of Maastricht, Maastricht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Maastricht, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048823000","display_name":"Cees Vermeer","orcid":"https://orcid.org/0000-0002-2300-8561","observed_orcids":["https://orcid.org/0000-0002-2300-8561"]},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"C. Vermeer","raw_affiliation_strings":["Department of Biochemistry, University of Maastricht, Maastricht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Maastricht, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034594973","display_name":"Robert J. Brummer","orcid":"https://orcid.org/0000-0002-0362-0008","observed_orcids":["https://orcid.org/0000-0002-0362-0008"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"R.\u2010J. M. Brummer","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112071786","display_name":"Reinhold W. Stockbr\u00fcgger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"R. W. Stockbr\u00fcgger","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital, Maastricht, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5025611672"],"corresponding_institution_ids":["https://openalex.org/I2800191616"],"apc_list":{"value":5250,"currency":"USD","value_usd":5250},"apc_paid":null,"fwci":3.1199,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.90759888,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"15","issue":"6","first_page":"783","last_page":"792"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.6937999725341797,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.6937999725341797,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.14489999413490295,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.11909999698400497,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.781000018119812},{"id":"https://openalex.org/keywords/osteopenia","display_name":"osteopenia","score":0.843999981880188},{"id":"https://openalex.org/keywords/bone-turnover","display_name":"bone turnover","score":0.9900000095367432},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.9959999918937683},{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.8500000238418579},{"id":"https://openalex.org/keywords/bone-specific-alkaline-phosphatase","display_name":"bone-specific alkaline phosphatase","score":0.9959999918937683},{"id":"https://openalex.org/keywords/deoxypyridinoline","display_name":"deoxypyridinoline","score":0.9800000190734863},{"id":"https://openalex.org/keywords/urinary-calcium-excretion","display_name":"urinary calcium excretion","score":0.984000027179718},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.9819999933242798},{"id":"https://openalex.org/keywords/small-bowel-involvement","display_name":"small bowel involvement","score":0.6370000243186951},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.7300000190734863}],"concepts":[{"id":"https://openalex.org/C673006","wikidata":"https://www.wikidata.org/wiki/Q4941581","display_name":"Bone resorption","level":2,"score":0.7838689088821411},{"id":"https://openalex.org/C2780787237","wikidata":"https://www.wikidata.org/wiki/Q1200841","display_name":"Deoxypyridinoline","level":5,"score":0.772225022315979},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.7692214846611023},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7513024806976318},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7263315916061401},{"id":"https://openalex.org/C2777083390","wikidata":"https://www.wikidata.org/wiki/Q1367706","display_name":"Osteopenia","level":4,"score":0.7232842445373535},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7136124968528748},{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.6356695890426636},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.5506941676139832},{"id":"https://openalex.org/C2776169692","wikidata":"https://www.wikidata.org/wiki/Q4941552","display_name":"Bone disease","level":3,"score":0.5481472611427307},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.5475068092346191},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.46981102228164673},{"id":"https://openalex.org/C146562846","wikidata":"https://www.wikidata.org/wiki/Q96649518","display_name":"Resorption","level":2,"score":0.46245551109313965},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.45552146434783936},{"id":"https://openalex.org/C2779280984","wikidata":"https://www.wikidata.org/wiki/Q1472","display_name":"Crohn's disease","level":3,"score":0.4550739824771881},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.44682469964027405},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.4354243874549866},{"id":"https://openalex.org/C2779240191","wikidata":"https://www.wikidata.org/wiki/Q6822340","display_name":"Metabolic bone disease","level":3,"score":0.4196707308292389},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1365339457988739},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1096058189868927},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05063319206237793},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001862","descriptor_name":"Bone Resorption","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008159","descriptor_name":"Lumbar Vertebrae","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015502","descriptor_name":"Absorptiometry, Photon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1046/j.1365-2036.2001.00997.x","doi":"https://doi.org/10.1046/j.1365-2036.2001.00997.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2036.2001.00997.x","pdf_url":null,"source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology &amp; Therapeutics","raw_type":"journal-article"},{"id":"pmid:11380316","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11380316","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary pharmacology & therapeutics","raw_type":"Journal Article"},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/aa53423e-5b3f-4acc-8d2e-7dfb34309229","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/aa53423e-5b3f-4acc-8d2e-7dfb34309229","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schoon, E J, Geerling, B J, van Dooren, I M A, Schurgers, L J, Vermeer, C, Brummer, R J M & Stockbr\u00fcgger, R W 2001, 'Abnormal bone turnover in long-standing Crohn's disease in remission.', Alimentary Pharmacology & Therapeutics, vol. 15, no. 6, pp. 783-792. https://doi.org/10.1046/j.1365-2036.2001.00997.x","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:um:oai:cris.maastrichtuniversity.nl:publications/aa53423e-5b3f-4acc-8d2e-7dfb34309229","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/aa53423e-5b3f-4acc-8d2e-7dfb34309229","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Alimentary Pharmacology &amp; Therapeutics, 15(6), 783 - 792. Wiley","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:3151460392","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Leon_Schurgers/publication/11959191_Abnormal_bone_turnover_in_longstanding_Crohns_disease_in_remission/links/09e4150795bbb1b30a000000.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/aa53423e-5b3f-4acc-8d2e-7dfb34309229","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/aa53423e-5b3f-4acc-8d2e-7dfb34309229","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schoon, E J, Geerling, B J, van Dooren, I M A, Schurgers, L J, Vermeer, C, Brummer, R J M & Stockbr\u00fcgger, R W 2001, 'Abnormal bone turnover in long-standing Crohn's disease in remission.', Alimentary Pharmacology & Therapeutics, vol. 15, no. 6, pp. 783-792. https://doi.org/10.1046/j.1365-2036.2001.00997.x","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W37010166","https://openalex.org/W1965354004","https://openalex.org/W1988620146","https://openalex.org/W1992544525","https://openalex.org/W2000099126","https://openalex.org/W2001328756","https://openalex.org/W2002764204","https://openalex.org/W2003317208","https://openalex.org/W2006044493","https://openalex.org/W2016157451","https://openalex.org/W2016666406","https://openalex.org/W2023471859","https://openalex.org/W2027388711","https://openalex.org/W2040045712","https://openalex.org/W2043002100","https://openalex.org/W2044433313","https://openalex.org/W2046116619","https://openalex.org/W2046704579","https://openalex.org/W2047516621","https://openalex.org/W2064855395","https://openalex.org/W2065637841","https://openalex.org/W2067522759","https://openalex.org/W2069518047","https://openalex.org/W2069798869","https://openalex.org/W2075292460","https://openalex.org/W2077182043","https://openalex.org/W2080410364","https://openalex.org/W2080770669","https://openalex.org/W2087734541","https://openalex.org/W2091295860","https://openalex.org/W2093106920","https://openalex.org/W2094348594","https://openalex.org/W2097146819","https://openalex.org/W2100307907","https://openalex.org/W2101177800","https://openalex.org/W2102539537","https://openalex.org/W2108875090","https://openalex.org/W2116826511","https://openalex.org/W2124512307","https://openalex.org/W2133275957","https://openalex.org/W2133627139","https://openalex.org/W2143628817","https://openalex.org/W2148688487","https://openalex.org/W2170680219","https://openalex.org/W2442024088","https://openalex.org/W2470156181","https://openalex.org/W2525867468","https://openalex.org/W2732353950","https://openalex.org/W3145833755","https://openalex.org/W3149191423","https://openalex.org/W3149527659"],"related_works":["https://openalex.org/W2077237681","https://openalex.org/W1999257045","https://openalex.org/W2046116619","https://openalex.org/W2088638821","https://openalex.org/W2046704579","https://openalex.org/W2123698598","https://openalex.org/W4391162400","https://openalex.org/W2466780928","https://openalex.org/W2084338700","https://openalex.org/W2480670464"],"abstract_inverted_index":{"BACKGROUND:":[0],"A":[1],"high":[2],"prevalence":[3],"of":[4,15,35,147,201],"osteoporosis":[5],"is":[6,25,176,189],"found":[7],"in":[8,37,46,109,112,138,169,173],"patients":[9,48,110,139],"with":[10,54,156],"Crohn's":[11,39,57,171],"disease.":[12,40],"The":[13],"pathogenesis":[14],"this":[16],"condition":[17],"seems":[18],"to":[19,142],"be":[20,196],"multifactorial":[21],"and":[22,51,59,79,83,88,153,160,182,193],"its":[23],"pathophysiology":[24,34],"still":[26],"not":[27,129],"completely":[28],"understood.":[29],"AIM:":[30],"To":[31],"elucidate":[32],"the":[33,148,199],"osteopenia":[36],"quiescent":[38,56],"METHODS:":[41],"Bone":[42,63,144,167],"turnover":[43,168],"was":[44,66,99,135,151],"studied":[45],"26":[47],"(13":[49],"males":[50],"13":[52],"females)":[53],"long-standing":[55,170],"disease":[58,172],"small":[60],"bowel":[61],"involvement.":[62],"mineral":[64,145],"density":[65,146],"assessed":[67],"by":[68,178],"dual":[69],"energy":[70],"X-ray":[71],"absorptiometry.":[72],"Biochemical":[73],"markers":[74,127],"for":[75,84,103],"bone":[76,85,104,125,180,184,202],"formation":[77,105,181],"(osteocalcin":[78],"bone-specific":[80,117,157],"alkaline":[81,118,158],"phosphatase)":[82],"resorption":[86,126],"(deoxypyridinoline":[87],"collagen":[89,161],"type":[90,162],"I":[91,163],"C-terminal":[92,164],"crosslinks)":[93],"were":[94,106,128],"measured.":[95],"Urinary":[96],"calcium":[97,133,187],"excretion":[98,134,188],"determined.":[100],"RESULTS:":[101],"Markers":[102],"significantly":[107,130,136,152],"lower":[108],"than":[111],"controls":[113],"(osteocalcin:":[114],"P=":[115],"0.027,":[116],"phosphatase:":[119],"P":[120],"<":[121],"0.001),":[122],"but":[123],"both":[124],"different.":[131],"Urine":[132,186],"decreased":[137],"(P=0.002)":[140],"compared":[141],"controls.":[143],"lumbar":[149],"spine":[150],"inversely":[154],"correlated":[155],"phosphatase":[159],"crosslinks.":[165],"CONCLUSIONS:":[166],"clinical":[174],"remission":[175],"characterized":[177],"suppressed":[179],"normal":[183],"resorption.":[185],"decreased.":[190],"Hence,":[191],"interventions":[192],"therapy":[194],"should":[195],"directed":[197],"towards":[198],"improvement":[200],"formation.":[203]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}