{"id":"https://openalex.org/W1995166000","doi":"https://doi.org/10.1590/s0365-05962009000500004","title":"Express\u00e3o de marcadores de prolifera\u00e7\u00e3o celular e apoptose no carcinoma espinocelular de pele e ceratose act\u00ednica","display_name":"Express\u00e3o de marcadores de prolifera\u00e7\u00e3o celular e apoptose no carcinoma espinocelular de pele e ceratose act\u00ednica","publication_year":2009,"publication_date":"2009-10-01","ids":{"openalex":"https://openalex.org/W1995166000","doi":"https://doi.org/10.1590/s0365-05962009000500004","mag":"1995166000","pmid":"https://pubmed.ncbi.nlm.nih.gov/20098848"},"language":"pt","primary_location":{"id":"doi:10.1590/s0365-05962009000500004","doi":"https://doi.org/10.1590/s0365-05962009000500004","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0365-05962009000500004","pdf_url":"https://www.scielo.br/j/abd/a/PcHrJnbgyNjGvBGVQggHfjK/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S21531352","display_name":"Anais Brasileiros de Dermatologia","issn_l":"0365-0596","issn":["0365-0596","1806-4841"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-70","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anais Brasileiros de Dermatologia","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1995166000"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.scielo.br/j/abd/a/PcHrJnbgyNjGvBGVQggHfjK/?lang=pt&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090213115","display_name":"Marilho Tadeu Dornelas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127435","display_name":"Sociedade Brasileira de Cirurgia Pl\u00e1stica","ror":"https://ror.org/034js7368","country_code":"BR","type":"other","lineage":["https://openalex.org/I4210127435"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Marilho Tadeu Dornelas","raw_affiliation_strings":["Sociedade Brasileira de Cirurgia Pl\u00e1stica"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sociedade Brasileira de Cirurgia Pl\u00e1stica","institution_ids":["https://openalex.org/I4210127435"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103227931","display_name":"Michele Fernandes Rodrigues","orcid":"https://orcid.org/0000-0002-0843-0844","observed_orcids":["https://orcid.org/0000-0002-0843-0844"]},"institutions":[{"id":"https://openalex.org/I101100930","display_name":"Universidade Federal de Juiz de Fora","ror":"https://ror.org/04yqw9c44","country_code":"BR","type":"education","lineage":["https://openalex.org/I101100930"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Michele Fernandes Rodrigues","raw_affiliation_strings":["em Sa\u00fade Brasileira na \u00e1rea de Imunologia , pela Faculdade de Medicina da Universidade Federal de Juiz de Fora (FM/UFJF) Juiz de Fora (MG) , Brasil","Bi\u00f3loga. Mestre em Sa\u00fade Brasileira na \u00e1rea de Imunologia pela Faculdade de Medicina da Universidade Federal de Juiz de Fora (FM/UFJF) -Juiz de Fora (MG), Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"em Sa\u00fade Brasileira na \u00e1rea de Imunologia , pela Faculdade de Medicina da Universidade Federal de Juiz de Fora (FM/UFJF) Juiz de Fora (MG) , Brasil","institution_ids":["https://openalex.org/I101100930"]},{"raw_affiliation_string":"Bi\u00f3loga. Mestre em Sa\u00fade Brasileira na \u00e1rea de Imunologia pela Faculdade de Medicina da Universidade Federal de Juiz de Fora (FM/UFJF) -Juiz de Fora (MG), Brasil","institution_ids":["https://openalex.org/I101100930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101983262","display_name":"Dequitier Carvalho Machado","orcid":"https://orcid.org/0000-0002-1939-5271","observed_orcids":["https://orcid.org/0000-0002-1939-5271","https://orcid.org/0000-0002-4874-8056"]},"institutions":[{"id":"https://openalex.org/I101100930","display_name":"Universidade Federal de Juiz de Fora","ror":"https://ror.org/04yqw9c44","country_code":"BR","type":"education","lineage":["https://openalex.org/I101100930"]},{"id":"https://openalex.org/I4210088805","display_name":"Hospital Universit\u00e1rio - Universidade Federal de Juiz de Fora","ror":"https://ror.org/0039g6563","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088805"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Dequitier Carvalho Machado","raw_affiliation_strings":["Acad\u00eamico da Faculdade de Medicina da Universidade Federal de Juiz de Fora. Estagi\u00e1rio no","Acad\u00eamico da Faculdade de Medicina da Universidade Federal de Juiz de Fora. Estagi\u00e1rio no Servi\u00e7o de Cirurgia Pl\u00e1stica do Hospital Universit\u00e1rio da","Universidade Federal de Juiz de Fora (HU/UFJF) -Juiz de Fora (MG), Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acad\u00eamico da Faculdade de Medicina da Universidade Federal de Juiz de Fora. Estagi\u00e1rio no","institution_ids":["https://openalex.org/I101100930"]},{"raw_affiliation_string":"Acad\u00eamico da Faculdade de Medicina da Universidade Federal de Juiz de Fora. Estagi\u00e1rio no Servi\u00e7o de Cirurgia Pl\u00e1stica do Hospital Universit\u00e1rio da","institution_ids":["https://openalex.org/I101100930","https://openalex.org/I4210088805"]},{"raw_affiliation_string":"Universidade Federal de Juiz de Fora (HU/UFJF) -Juiz de Fora (MG), Brasil","institution_ids":["https://openalex.org/I101100930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034647923","display_name":"\u00c2ngela Maria Gollner","orcid":"https://orcid.org/0000-0002-9687-5877","observed_orcids":["https://orcid.org/0000-0002-9687-5877"]},"institutions":[{"id":"https://openalex.org/I101100930","display_name":"Universidade Federal de Juiz de Fora","ror":"https://ror.org/04yqw9c44","country_code":"BR","type":"education","lineage":["https://openalex.org/I101100930"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"\u00c2ngela Maria Gollner","raw_affiliation_strings":["Universidade Federal de Juiz de Fora, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Juiz de Fora, Brasil","institution_ids":["https://openalex.org/I101100930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006512215","display_name":"Ana Paula Ferreira","orcid":"https://orcid.org/0000-0002-0020-1828","observed_orcids":["https://orcid.org/0000-0002-0020-1828"]},"institutions":[{"id":"https://openalex.org/I101100930","display_name":"Universidade Federal de Juiz de Fora","ror":"https://ror.org/04yqw9c44","country_code":"BR","type":"education","lineage":["https://openalex.org/I101100930"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana Paula Ferreira","raw_affiliation_strings":["Universidade Federal de Juiz de Fora, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Juiz de Fora, Brasil","institution_ids":["https://openalex.org/I101100930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5090213115"],"corresponding_institution_ids":["https://openalex.org/I4210127435"],"apc_list":{"value":1700,"currency":"USD","value_usd":1700},"apc_paid":{"value":1700,"currency":"USD","value_usd":1700},"fwci":1.9881,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.85100802,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"84","issue":"5","first_page":"469","last_page":"475"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11868","display_name":"Cancer and Skin Lesions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/squamous-cell-carcinoma","display_name":"squamous cell carcinoma","score":0.9399999976158142},{"id":"https://openalex.org/keywords/actinic-keratosis","display_name":"actinic keratosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/proliferation-markers","display_name":"cell proliferation markers","score":0.8270000219345093},{"id":"https://openalex.org/keywords/apoptosis-markers","display_name":"apoptosis markers","score":0.9800000190734863},{"id":"https://openalex.org/keywords/pcna","display_name":"PCNA","score":0.7910000085830688},{"id":"https://openalex.org/keywords/ki-67","display_name":"Ki-67","score":1.0},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.996999979019165},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":1.0},{"id":"https://openalex.org/keywords/cell-immortalization","display_name":"cell immortalization","score":0.8550000190734863},{"id":"https://openalex.org/keywords/eyelid-skin","display_name":"eyelid skin","score":0.5920000076293945},{"id":"https://openalex.org/keywords/blepharoplasty","display_name":"blepharoplasty","score":0.7120000123977661},{"id":"https://openalex.org/keywords/precancerous-lesions","display_name":"precancerous lesions","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C2777873816","wikidata":"https://www.wikidata.org/wiki/Q422225","display_name":"Actinic keratosis","level":3,"score":0.9498279094696045},{"id":"https://openalex.org/C2778648961","wikidata":"https://www.wikidata.org/wiki/Q3667186","display_name":"Keratosis","level":2,"score":0.6190917491912842},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5944703221321106},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5118852853775024},{"id":"https://openalex.org/C2777845685","wikidata":"https://www.wikidata.org/wiki/Q2166371","display_name":"Seborrheic keratosis","level":2,"score":0.5090922713279724},{"id":"https://openalex.org/C34688535","wikidata":"https://www.wikidata.org/wiki/Q418732","display_name":"Proliferating cell nuclear antigen","level":3,"score":0.4954339265823364},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4678032696247101},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4618021845817566},{"id":"https://openalex.org/C2778804307","wikidata":"https://www.wikidata.org/wiki/Q809758","display_name":"Basal cell carcinoma","level":3,"score":0.45491576194763184},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4420356750488281},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.41175079345703125},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.4052903652191162}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018809","descriptor_name":"Proliferating Cell Nuclear Antigen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018809","descriptor_name":"Proliferating Cell Nuclear Antigen","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D019394","descriptor_name":"Ki-67 Antigen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019394","descriptor_name":"Ki-67 Antigen","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055623","descriptor_name":"Keratosis, Actinic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055623","descriptor_name":"Keratosis, Actinic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1590/s0365-05962009000500004","doi":"https://doi.org/10.1590/s0365-05962009000500004","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0365-05962009000500004","pdf_url":"https://www.scielo.br/j/abd/a/PcHrJnbgyNjGvBGVQggHfjK/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S21531352","display_name":"Anais Brasileiros de Dermatologia","issn_l":"0365-0596","issn":["0365-0596","1806-4841"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-70","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anais Brasileiros de Dermatologia","raw_type":"journal-article"},{"id":"pmid:20098848","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20098848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anais brasileiros de dermatologia","raw_type":"English Abstract"},{"id":"pmh:oai:scielo:S0365-05962009000500004","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962009000500004","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anais Brasileiros de Dermatologia v.84 n.5 2009","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2306985","doi":null,"is_oa":true,"landing_page_url":"http://americanae.aecid.es/americanae/es/registros/registro.do?tipoRegistro=MTD&idBib=2306985","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UFJF","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:americanae.aecid.es:2497140","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962009000500004","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anais Brasileiros de Dermatologia v.84 n.5 2009","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:1326390c51fe46cf8fa6465ca89cf9a3","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1326390c51fe46cf8fa6465ca89cf9a3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anais Brasileiros de Dermatologia, Vol 84, Iss 5, Pp 469-475 (2009)","raw_type":"article"},{"id":"pmh:oai:hermes.cpd.ufjf.br:ufjf/8845","doi":null,"is_oa":true,"landing_page_url":"https://repositorio.ufjf.br/jspui/handle/ufjf/8845","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UFJF","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1590/s0365-05962009000500004","doi":"https://doi.org/10.1590/s0365-05962009000500004","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0365-05962009000500004","pdf_url":"https://www.scielo.br/j/abd/a/PcHrJnbgyNjGvBGVQggHfjK/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S21531352","display_name":"Anais Brasileiros de Dermatologia","issn_l":"0365-0596","issn":["0365-0596","1806-4841"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-70","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anais Brasileiros de Dermatologia","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320324372","display_name":"Universidade Federal de Juiz de Fora","ror":"https://ror.org/04yqw9c44"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1995166000.pdf","grobid_xml":"https://content.openalex.org/works/W1995166000.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W41026040","https://openalex.org/W1499486457","https://openalex.org/W1977464187","https://openalex.org/W2006378484","https://openalex.org/W2017082146","https://openalex.org/W2056014037","https://openalex.org/W2078137081","https://openalex.org/W2082702169","https://openalex.org/W2089795803","https://openalex.org/W2093929453","https://openalex.org/W2102528174","https://openalex.org/W2102637198","https://openalex.org/W2110836068","https://openalex.org/W2157923053","https://openalex.org/W2441827817","https://openalex.org/W6675331496"],"related_works":["https://openalex.org/W7009682078","https://openalex.org/W1994281612","https://openalex.org/W3015629657","https://openalex.org/W2092463111","https://openalex.org/W2046117348","https://openalex.org/W2091850478","https://openalex.org/W2185127727","https://openalex.org/W4388971185","https://openalex.org/W2264558280","https://openalex.org/W2056573152"],"abstract_inverted_index":{"BACKGROUND:":[0],"Skin":[1],"cancer":[2,10],"is":[3],"the":[4,23,26,51,69,138,170,173,190],"most":[5],"frequent":[6],"type":[7],"of":[8,25,71,73,99,134,146,163,179,185,195],"human":[9],"and":[11,78,87,107,142,165,167,197],"has":[12],"shown":[13],"an":[14],"increase":[15],"in":[16,47,57,81,118,131,137,144,154,161,169,189,199],"its":[17],"incidence.":[18],"In":[19],"many":[20],"cases,":[21],"before":[22],"onset":[24],"carcinoma,":[27,102],"there":[28],"might":[29],"be":[30],"a":[31],"precursor":[32],"lesion--actinic":[33],"keratosis,":[34],"which":[35,61],"can":[36],"develop":[37],"into":[38],"squamous":[39,84,100,147],"cell":[40,74,85,101,148,205],"carcinoma.":[41,149],"Studies":[42],"have":[43,54,62],"been":[44],"carried":[45],"out":[46],"order":[48],"to":[49],"determine":[50],"parameters":[52],"that":[53],"prognostic":[55],"significance":[56],"predicting":[58],"those":[59],"tumors":[60],"more":[63],"aggressive":[64],"behavior.":[65],"OBJECTIVE:":[66],"To":[67],"evaluate":[68],"expression":[70,153,160,178,184,194],"markers":[72],"proliferation":[75,188],"(PCNA,":[76],"Ki-67)":[77],"apoptosis":[79],"(p53,Bcl-2)":[80],"patients":[82,98,200],"with":[83,104,121,182,201],"carcinoma":[86,166,191],"actinic":[88,105,135,202],"keratosis.":[89],"METHOD:":[90],"We":[91],"studied":[92],"samples":[93,110],"from":[94,111,140,172],"30":[95],"patients,":[96],"ten":[97,103,108],"keratosis":[106,136,164,203],"lesion-free":[109],"blepharoplasty.":[112],"RESULTS:":[113],"p53":[114,196],"protein":[115],"was":[116,126],"expressed":[117,127],"all":[119,155],"cases":[120,133,145,162],"different":[122],"quantitative":[123],"patterns.":[124],"Bcl-2":[125,186,198],"at":[128],"low":[129,183],"intensity":[130],"six":[132],"skin":[139,171],"blepharoplasty":[141],"negative":[143,168],"PCNA":[150],"showed":[151,158],"intense":[152],"samples.":[156],"Ki-67":[157,180],"variable":[159],"eyelid.":[174],"CONCLUSION:":[175],"The":[176],"high":[177],"associated":[181],"indicates":[187,204],"group.":[192],"Thus,":[193],"immortalization.":[206]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}