{"id":"https://openalex.org/W1995037331","doi":"https://doi.org/10.1016/0142-9612(96)85758-9","title":"Role of material surfaces in regulating bone and cartilage cell response","display_name":"Role of material surfaces in regulating bone and cartilage cell response","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W1995037331","doi":"https://doi.org/10.1016/0142-9612(96)85758-9","mag":"1995037331","pmid":"https://pubmed.ncbi.nlm.nih.gov/8624390"},"language":"en","primary_location":{"id":"doi:10.1016/0142-9612(96)85758-9","doi":"https://doi.org/10.1016/0142-9612(96)85758-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0142-9612(96)85758-9","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1995037331"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052368052","display_name":"Barbara D. Boyan","orcid":"https://orcid.org/0000-0002-9642-0311","observed_orcids":["https://orcid.org/0000-0002-9642-0311"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Barbara D. Boyan","raw_affiliation_strings":["Department of Orthopaedics, University of Texas Health Science Center at San Antonio 78284-7774, USA","Department of Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","Department of Periodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, University of Texas Health Science Center at San Antonio 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Periodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Thomas W. Hummert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas W. Hummert","raw_affiliation_strings":["Department of Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","Department of Prosthodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Prosthodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073060614","display_name":"David D. Dean","orcid":"https://orcid.org/0000-0002-4512-9065","observed_orcids":["https://orcid.org/0000-0002-4512-9065"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David D. Dean","raw_affiliation_strings":["Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029880479","display_name":"Zvi Schwartz","orcid":"https://orcid.org/0000-0003-1612-9223","observed_orcids":["https://orcid.org/0000-0003-1612-9223","https://orcid.org/0000-0001-9254-5670"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]},{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Zvi Schwartz","raw_affiliation_strings":["Department of Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","Department of Periodontics, Hebrew University Hadassah Faculty of Dental Medicine, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7774, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Periodontics, Hebrew University Hadassah Faculty of Dental Medicine, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052368052"],"corresponding_institution_ids":["https://openalex.org/I165951966"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":10.1649,"has_fulltext":false,"cited_by_count":1349,"citation_normalized_percentile":{"value":0.99091184,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"17","issue":"2","first_page":"137","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cell-substrate-interaction","display_name":"cell-substrate interaction","score":0.5479999780654907},{"id":"https://openalex.org/keywords/surface-topography","display_name":"surface topography","score":0.6620000004768372},{"id":"https://openalex.org/keywords/surface-chemistry","display_name":"surface chemistry","score":0.953000009059906},{"id":"https://openalex.org/keywords/osteoblasts","display_name":"osteoblasts","score":0.7799999713897705},{"id":"https://openalex.org/keywords/chondrocytes","display_name":"chondrocytes","score":1.0},{"id":"https://openalex.org/keywords/bone-tissue-engineering","display_name":"bone tissue engineering","score":0.7540000081062317},{"id":"https://openalex.org/keywords/cartilage-tissue-engineering","display_name":"cartilage tissue engineering","score":0.9980000257492065},{"id":"https://openalex.org/keywords/surface-roughness","display_name":"surface roughness","score":0.699999988079071},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.7279999852180481},{"id":"https://openalex.org/keywords/cell-alignment","display_name":"cell alignment","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cytoskeleton","display_name":"cytoskeleton","score":0.6119999885559082},{"id":"https://openalex.org/keywords/cell-phenotype","display_name":"cell phenotype","score":0.5180000066757202},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6436979174613953},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.5566594004631042},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.55447918176651},{"id":"https://openalex.org/C2781403057","wikidata":"https://www.wikidata.org/wiki/Q775480","display_name":"Chondrocyte","level":3,"score":0.5381380915641785},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5073363184928894},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.5024402141571045},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5005249977111816},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.49680307507514954},{"id":"https://openalex.org/C107365816","wikidata":"https://www.wikidata.org/wiki/Q114817","display_name":"Surface roughness","level":2,"score":0.42693328857421875},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4021717309951782},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.38640862703323364},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.31304416060447693},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27219438552856445},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1517375111579895},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12978124618530273},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1260370910167694},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10927537083625793},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000327","descriptor_name":"Adsorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010006","descriptor_name":"Osteoblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D010006","descriptor_name":"Osteoblasts","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014025","descriptor_name":"Titanium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0142-9612(96)85758-9","doi":"https://doi.org/10.1016/0142-9612(96)85758-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0142-9612(96)85758-9","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:8624390","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8624390","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1800886826","display_name":"ROLE OF MEMBRANES AND MINERALIZATION OF BONES AND TEETH","funder_award_id":"R01DE005937","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G3522403492","display_name":null,"funder_award_id":"DE 05623","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G7582888109","display_name":"IMPLANT MATERIALS EFFECT ON CELLULAR RESPONSE","funder_award_id":"F32DE005623","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G8396363316","display_name":"BONE FACTORS AND ENDOCHONDRAL OSSIFICATION","funder_award_id":"R01DE008603","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"}],"funders":[{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W181406011","https://openalex.org/W344580765","https://openalex.org/W587827298","https://openalex.org/W600570182","https://openalex.org/W1504476025","https://openalex.org/W1552908307","https://openalex.org/W1559994288","https://openalex.org/W1776717194","https://openalex.org/W1783306858","https://openalex.org/W1832236335","https://openalex.org/W1855561741","https://openalex.org/W1869725238","https://openalex.org/W1959403247","https://openalex.org/W1974822377","https://openalex.org/W1982968783","https://openalex.org/W1986469118","https://openalex.org/W1987093895","https://openalex.org/W1989455035","https://openalex.org/W1992268845","https://openalex.org/W1997350459","https://openalex.org/W1997969373","https://openalex.org/W1999130587","https://openalex.org/W2000463542","https://openalex.org/W2009598071","https://openalex.org/W2010137939","https://openalex.org/W2010848983","https://openalex.org/W2018603683","https://openalex.org/W2018655931","https://openalex.org/W2021434165","https://openalex.org/W2023222010","https://openalex.org/W2025534967","https://openalex.org/W2025663212","https://openalex.org/W2029415593","https://openalex.org/W2031915220","https://openalex.org/W2034227973","https://openalex.org/W2034364335","https://openalex.org/W2048705258","https://openalex.org/W2049442687","https://openalex.org/W2049454199","https://openalex.org/W2050273631","https://openalex.org/W2063257376","https://openalex.org/W2064135579","https://openalex.org/W2072487937","https://openalex.org/W2072564932","https://openalex.org/W2073033404","https://openalex.org/W2077544594","https://openalex.org/W2079235642","https://openalex.org/W2080701527","https://openalex.org/W2084936639","https://openalex.org/W2092050830","https://openalex.org/W2093185233","https://openalex.org/W2094172455","https://openalex.org/W2094291999","https://openalex.org/W2094954133","https://openalex.org/W2103998761","https://openalex.org/W2107858832","https://openalex.org/W2108347790","https://openalex.org/W2109462668","https://openalex.org/W2112093320","https://openalex.org/W2113240961","https://openalex.org/W2113613856","https://openalex.org/W2132309525","https://openalex.org/W2134335726","https://openalex.org/W2148872895","https://openalex.org/W2149003995","https://openalex.org/W2158710568","https://openalex.org/W2179433498","https://openalex.org/W2229813099","https://openalex.org/W2244585777","https://openalex.org/W2266855903","https://openalex.org/W2334811311","https://openalex.org/W2342185864","https://openalex.org/W2416715422","https://openalex.org/W2418155129","https://openalex.org/W2418958490","https://openalex.org/W2419674145","https://openalex.org/W2560497666","https://openalex.org/W2906544593","https://openalex.org/W3025174573","https://openalex.org/W3156480031","https://openalex.org/W4230197875","https://openalex.org/W4239171241","https://openalex.org/W4297672735","https://openalex.org/W4387161900"],"related_works":["https://openalex.org/W2145659328","https://openalex.org/W2327354937","https://openalex.org/W154322313","https://openalex.org/W1970438213","https://openalex.org/W2062983174","https://openalex.org/W1488436001","https://openalex.org/W2189362338","https://openalex.org/W2020655054","https://openalex.org/W2019192726","https://openalex.org/W2775181523"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":24},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":30},{"year":2022,"cited_by_count":29},{"year":2021,"cited_by_count":46},{"year":2020,"cited_by_count":36},{"year":2019,"cited_by_count":63},{"year":2018,"cited_by_count":56},{"year":2017,"cited_by_count":51},{"year":2016,"cited_by_count":69},{"year":2015,"cited_by_count":55},{"year":2014,"cited_by_count":81},{"year":2013,"cited_by_count":53},{"year":2012,"cited_by_count":70}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
