{"id":"https://openalex.org/W1994785099","doi":"https://doi.org/10.1016/0955-0674(94)90049-3","title":"Differentiation and cell death: lessons from the immune system","display_name":"Differentiation and cell death: lessons from the immune system","publication_year":1994,"publication_date":"1994-12-01","ids":{"openalex":"https://openalex.org/W1994785099","doi":"https://doi.org/10.1016/0955-0674(94)90049-3","mag":"1994785099","pmid":"https://pubmed.ncbi.nlm.nih.gov/7880527"},"language":"en","primary_location":{"id":"doi:10.1016/0955-0674(94)90049-3","doi":"https://doi.org/10.1016/0955-0674(94)90049-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0955-0674(94)90049-3","pdf_url":null,"source":{"id":"https://openalex.org/S103771297","display_name":"Current Opinion in Cell Biology","issn_l":"0955-0674","issn":["0955-0674","1879-0410"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Cell Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076793020","display_name":"Gerald P. Linette","orcid":"https://orcid.org/0000-0001-6147-6115","observed_orcids":["https://orcid.org/0000-0001-6147-6115"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerald P. Linette","raw_affiliation_strings":["Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109113107","display_name":"Stanley J. Korsmeyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stanley J. Korsmeyer","raw_affiliation_strings":["Howard Hughes Medical Institute, Washington University School of Medicine, Box 8022, 660 South Euclid Avenue, St Louis, MO 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Washington University School of Medicine, Box 8022, 660 South Euclid Avenue, St Louis, MO 63110, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.8079,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.65968586,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"6","issue":"6","first_page":"809","last_page":"815"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.06669999659061432,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.6880000233650208},{"id":"https://openalex.org/keywords/cell-differentiation","display_name":"cell differentiation","score":0.765999972820282},{"id":"https://openalex.org/keywords/cell-death","display_name":"cell death","score":0.7419999837875366},{"id":"https://openalex.org/keywords/lymphopoiesis","display_name":"lymphocyte development","score":0.7879999876022339},{"id":"https://openalex.org/keywords/b-cell-development","display_name":"B cell development","score":0.8069999814033508},{"id":"https://openalex.org/keywords/t-cell-development","display_name":"T cell development","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9160000085830688},{"id":"https://openalex.org/keywords/positive-selection","display_name":"positive selection","score":0.8659999966621399},{"id":"https://openalex.org/keywords/prosurvival-signaling","display_name":"survival signaling","score":0.800000011920929}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9147522449493408},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.7159780263900757},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6559479236602783},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.6105777025222778},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5851094722747803},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5606839656829834},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.5417791604995728},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.49202415347099304},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.43293601274490356},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3552767038345337},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2142062485218048},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12104809284210205}],"mesh":[{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0955-0674(94)90049-3","doi":"https://doi.org/10.1016/0955-0674(94)90049-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0955-0674(94)90049-3","pdf_url":null,"source":{"id":"https://openalex.org/S103771297","display_name":"Current Opinion in Cell Biology","issn_l":"0955-0674","issn":["0955-0674","1879-0410"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Cell Biology","raw_type":"journal-article"},{"id":"pmid:7880527","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7880527","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in cell biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W26755955","https://openalex.org/W1481927174","https://openalex.org/W1524516556","https://openalex.org/W1572034293","https://openalex.org/W1652976025","https://openalex.org/W1668774261","https://openalex.org/W1836124358","https://openalex.org/W1898236813","https://openalex.org/W1913179054","https://openalex.org/W1966899632","https://openalex.org/W1970629830","https://openalex.org/W1971234510","https://openalex.org/W1977546470","https://openalex.org/W1977707442","https://openalex.org/W1995775226","https://openalex.org/W1997208169","https://openalex.org/W2000646975","https://openalex.org/W2001917467","https://openalex.org/W2018486465","https://openalex.org/W2022847127","https://openalex.org/W2022978700","https://openalex.org/W2025818427","https://openalex.org/W2030204732","https://openalex.org/W2032592355","https://openalex.org/W2033847504","https://openalex.org/W2036274324","https://openalex.org/W2036859226","https://openalex.org/W2037473273","https://openalex.org/W2038377343","https://openalex.org/W2043066069","https://openalex.org/W2047941892","https://openalex.org/W2050515006","https://openalex.org/W2056374213","https://openalex.org/W2057257609","https://openalex.org/W2062999278","https://openalex.org/W2063176993","https://openalex.org/W2068903461","https://openalex.org/W2078447006","https://openalex.org/W2078458079","https://openalex.org/W2081560586","https://openalex.org/W2089883223","https://openalex.org/W2095330021","https://openalex.org/W2108257172","https://openalex.org/W2110935912","https://openalex.org/W2112070235","https://openalex.org/W2112161923","https://openalex.org/W2132963869","https://openalex.org/W2134979684","https://openalex.org/W2143772496","https://openalex.org/W2148045692","https://openalex.org/W2174800991","https://openalex.org/W2188060873","https://openalex.org/W2188651990","https://openalex.org/W2189959642","https://openalex.org/W2316756341","https://openalex.org/W2333511894","https://openalex.org/W2344615469","https://openalex.org/W4251633039","https://openalex.org/W6634404273","https://openalex.org/W6642038248","https://openalex.org/W6642787434","https://openalex.org/W6656249533","https://openalex.org/W6656966048","https://openalex.org/W6673207166","https://openalex.org/W6699193769"],"related_works":["https://openalex.org/W1520517081","https://openalex.org/W2053480920","https://openalex.org/W2142314780","https://openalex.org/W2037539040","https://openalex.org/W2002795468","https://openalex.org/W2126943109","https://openalex.org/W4493233","https://openalex.org/W2001232873","https://openalex.org/W2030945682","https://openalex.org/W2065934473"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
