{"id":"https://openalex.org/W1994529552","doi":"https://doi.org/10.1016/j.ijpharm.2007.06.014","title":"In vivo evaluation of lipid nanocapsules as a promising colloidal carrier for paclitaxel","display_name":"In vivo evaluation of lipid nanocapsules as a promising colloidal carrier for paclitaxel","publication_year":2007,"publication_date":"2007-06-20","ids":{"openalex":"https://openalex.org/W1994529552","doi":"https://doi.org/10.1016/j.ijpharm.2007.06.014","mag":"1994529552","pmid":"https://pubmed.ncbi.nlm.nih.gov/17646066"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijpharm.2007.06.014","doi":"https://doi.org/10.1016/j.ijpharm.2007.06.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijpharm.2007.06.014","pdf_url":null,"source":{"id":"https://openalex.org/S131016564","display_name":"International Journal of Pharmaceutics","issn_l":"0378-5173","issn":["0378-5173","1873-3476"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Pharmaceutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007708517","display_name":"Franck Lac\u0153uille","orcid":"https://orcid.org/0000-0002-7070-7664","observed_orcids":["https://orcid.org/0000-0002-7070-7664"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"F. Lacoeuille","raw_affiliation_strings":["Inserm U646, 10 rue A. Boquel, F-49100 Angers, France. franck.lacoeuille@univ-angers.fr","Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","University of Angers, 10 rue A. Boquel, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France. franck.lacoeuille@univ-angers.fr","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Angers, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051772553","display_name":"Fran\u00e7ois Hindr\u00e9","orcid":"https://orcid.org/0000-0002-2727-7996","observed_orcids":["https://orcid.org/0000-0002-2727-7996"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F. Hindre","raw_affiliation_strings":["Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","University of Angers, 10 rue A. Boquel, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Angers, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":null,"display_name":"F. Moal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F. Moal","raw_affiliation_strings":["Laboratory HIFI, UPRESS EA3589, University of Angers, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory HIFI, UPRESS EA3589, University of Angers, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113549855","display_name":"J. Roux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Roux","raw_affiliation_strings":["SCAHU, UFR Medecine, University of Angers, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SCAHU, UFR Medecine, University of Angers, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035704254","display_name":"Catherine Passirani","orcid":"https://orcid.org/0000-0001-6024-7839","observed_orcids":["https://orcid.org/0000-0001-6024-7839"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Passirani","raw_affiliation_strings":["Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","University of Angers, 10 rue A. Boquel, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Angers, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021098221","display_name":"Olivier Couturier","orcid":"https://orcid.org/0000-0002-4900-7807","observed_orcids":["https://orcid.org/0000-0002-4900-7807"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"O. Couturier","raw_affiliation_strings":["Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","University of Angers, 10 rue A. Boquel, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Angers, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047468439","display_name":"Paul Cal\u00e8s","orcid":"https://orcid.org/0000-0003-4866-5274","observed_orcids":["https://orcid.org/0000-0003-4866-5274"]},"institutions":[{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P. Cales","raw_affiliation_strings":["Laboratory HIFI, UPRESS EA3589, University of Angers, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory HIFI, UPRESS EA3589, University of Angers, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108209862","display_name":"Jean Jacques Le Jeune","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J.J. Le Jeune","raw_affiliation_strings":["Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","University of Angers, 10 rue A. Boquel, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Angers, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087419324","display_name":"Alf Lamprecht","orcid":"https://orcid.org/0000-0002-4492-1579","observed_orcids":["https://orcid.org/0000-0002-4492-1579"]},"institutions":[{"id":"https://openalex.org/I90843659","display_name":"Universit\u00e9 de Franche-Comt\u00e9","ror":"https://ror.org/03pcc9z86","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405256580","https://openalex.org/I90843659"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A. Lamprecht","raw_affiliation_strings":["Laboratory of Pharmaceutical Engineering, Faculty of Medicine and Pharmacy, University of Franche-Comt\u00e9, Place Saint Jacques, F-25030 Besan\u00e7on, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmaceutical Engineering, Faculty of Medicine and Pharmacy, University of Franche-Comt\u00e9, Place Saint Jacques, F-25030 Besan\u00e7on, France","institution_ids":["https://openalex.org/I90843659"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041610975","display_name":"Jean\u2010Pierre Beno\u00eet","orcid":"https://orcid.org/0000-0002-6178-7199","observed_orcids":["https://orcid.org/0000-0002-6178-7199","https://orcid.org/0000-0001-6022-6667"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I49451733","display_name":"Universit\u00e9 d'Angers","ror":"https://ror.org/04yrqp957","country_code":"FR","type":"education","lineage":["https://openalex.org/I49451733"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J.P. Benoit","raw_affiliation_strings":["Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","University of Angers, 10 rue A. Boquel, F-49100 Angers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U646, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Angers, 10 rue A. Boquel, F-49100 Angers, France","institution_ids":["https://openalex.org/I49451733"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5007708517"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I49451733"],"apc_list":{"value":4650,"currency":"USD","value_usd":4650},"apc_paid":null,"fwci":2.2356,"has_fulltext":false,"cited_by_count":98,"citation_normalized_percentile":{"value":0.85340017,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"344","issue":"1-2","first_page":"143","last_page":"149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipid-nanocapsules","display_name":"lipid nanocapsules","score":0.9369999766349792},{"id":"https://openalex.org/keywords/paclitaxel","display_name":"paclitaxel","score":1.0},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.7289999723434448},{"id":"https://openalex.org/keywords/tissue-distribution","display_name":"tissue distribution","score":0.8989999890327454},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.8320000171661377},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8320000171661377},{"id":"https://openalex.org/keywords/colloidal-carriers","display_name":"colloidal carriers","score":0.48899999260902405},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.5929999947547913},{"id":"https://openalex.org/keywords/survival-time","display_name":"survival time","score":0.3179999887943268}],"concepts":[{"id":"https://openalex.org/C2777292972","wikidata":"https://www.wikidata.org/wiki/Q423762","display_name":"Paclitaxel","level":3,"score":0.793083906173706},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6918341517448425},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6506441831588745},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.5962855219841003},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5866877436637878},{"id":"https://openalex.org/C204399865","wikidata":"https://www.wikidata.org/wiki/Q17157402","display_name":"Nanocapsules","level":3,"score":0.5750460028648376},{"id":"https://openalex.org/C18150654","wikidata":"https://www.wikidata.org/wiki/Q17153796","display_name":"Nanocarriers","level":3,"score":0.5231743454933167},{"id":"https://openalex.org/C13245373","wikidata":"https://www.wikidata.org/wiki/Q3715494","display_name":"Drug carrier","level":3,"score":0.5168819427490234},{"id":"https://openalex.org/C2777807558","wikidata":"https://www.wikidata.org/wiki/Q4914764","display_name":"Biodistribution","level":3,"score":0.500946044921875},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.4133966565132141},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.38597795367240906},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.33283621072769165},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20782214403152466},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.1977105438709259},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1644870936870575},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.16027000546455383},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13040652871131897},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.13005036115646362},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12117260694503784},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1084202229976654},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.10206645727157593},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07631763815879822},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001682","descriptor_name":"Biological Availability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003102","descriptor_name":"Colloids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004339","descriptor_name":"Drug Compounding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006207","descriptor_name":"Half-Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008114","descriptor_name":"Liver Neoplasms, Experimental","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D008114","descriptor_name":"Liver Neoplasms, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008114","descriptor_name":"Liver Neoplasms, Experimental","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053769","descriptor_name":"Nanocapsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ijpharm.2007.06.014","doi":"https://doi.org/10.1016/j.ijpharm.2007.06.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijpharm.2007.06.014","pdf_url":null,"source":{"id":"https://openalex.org/S131016564","display_name":"International Journal of Pharmaceutics","issn_l":"0378-5173","issn":["0378-5173","1873-3476"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Pharmaceutics","raw_type":"journal-article"},{"id":"pmid:17646066","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17646066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of pharmaceutics","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:inserm-00258366v1","doi":null,"is_oa":false,"landing_page_url":"https://inserm.hal.science/inserm-00258366","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharmaceutics, 2007, 344 (1-2), pp.143-9. ⟨10.1016/j.ijpharm.2007.06.014⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9074000120162964,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W17151634","https://openalex.org/W204512410","https://openalex.org/W1205374584","https://openalex.org/W1988608956","https://openalex.org/W2002516695","https://openalex.org/W2014038668","https://openalex.org/W2018858097","https://openalex.org/W2019987582","https://openalex.org/W2024797231","https://openalex.org/W2025377771","https://openalex.org/W2030822319","https://openalex.org/W2052884059","https://openalex.org/W2055774545","https://openalex.org/W2058360844","https://openalex.org/W2060240525","https://openalex.org/W2061346349","https://openalex.org/W2085740491","https://openalex.org/W2100225360","https://openalex.org/W2104819002","https://openalex.org/W2110278157","https://openalex.org/W2110956821","https://openalex.org/W2123888680","https://openalex.org/W2184694295","https://openalex.org/W2318949112","https://openalex.org/W2398775131","https://openalex.org/W2415191584","https://openalex.org/W6600701866"],"related_works":["https://openalex.org/W2016951629","https://openalex.org/W2144853369","https://openalex.org/W2316865774","https://openalex.org/W2058958377","https://openalex.org/W2511610444","https://openalex.org/W3212775341","https://openalex.org/W2914462769","https://openalex.org/W4293103036","https://openalex.org/W2986483031","https://openalex.org/W2762426134"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}