{"id":"https://openalex.org/W1994473965","doi":"https://doi.org/10.1038/ncb2112","title":"SUMOylation of the GTPase Rac1 is required for optimal cell migration","display_name":"SUMOylation of the GTPase Rac1 is required for optimal cell migration","publication_year":2010,"publication_date":"2010-10-10","ids":{"openalex":"https://openalex.org/W1994473965","doi":"https://doi.org/10.1038/ncb2112","mag":"1994473965","pmid":"https://pubmed.ncbi.nlm.nih.gov/20935639","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2992316"},"language":"en","primary_location":{"id":"doi:10.1038/ncb2112","doi":"https://doi.org/10.1038/ncb2112","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ncb2112","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2992316","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020593430","display_name":"Sonia Castillo\u2010Lluva","orcid":"https://orcid.org/0000-0001-5357-7178","observed_orcids":["https://orcid.org/0000-0001-5357-7178","https://orcid.org/0000-0003-2492-1421","https://orcid.org/0009-0007-9587-7233"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sonia Castillo-Lluva","raw_affiliation_strings":["Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, M20 4BX, UK","Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, M20 4BX, UK","institution_ids":["https://openalex.org/I28407311","https://openalex.org/I4210129527"]},{"raw_affiliation_string":"Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311","https://openalex.org/I4210129527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030297260","display_name":"Michael H. Tatham","orcid":"https://orcid.org/0000-0001-6986-1691","observed_orcids":["https://orcid.org/0000-0001-6986-1691"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael H. Tatham","raw_affiliation_strings":["Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK","Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104085684","display_name":"Richard C. Jones","orcid":"https://orcid.org/0000-0002-2155-6855","observed_orcids":["https://orcid.org/0000-0002-2155-6855"]},"institutions":[{"id":"https://openalex.org/I1304557061","display_name":"National Center for Toxicological Research","ror":"https://ror.org/05jmhh281","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1304557061","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard C. Jones","raw_affiliation_strings":["National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, 72079, AR, USA","Current address: MS Bioworks, 3950 Varsity Drive, Ann Arbor, MI 48108, USA.,","National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, 72079, AR, USA","institution_ids":["https://openalex.org/I1304557061","https://openalex.org/I1320320070"]},{"raw_affiliation_string":"Current address: MS Bioworks, 3950 Varsity Drive, Ann Arbor, MI 48108, USA.,","institution_ids":[]},{"raw_affiliation_string":"National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, USA","institution_ids":["https://openalex.org/I1304557061","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002315758","display_name":"Ellis Jaffray","orcid":"https://orcid.org/0000-0001-7827-4579","observed_orcids":["https://orcid.org/0000-0001-7827-4579"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ellis G. Jaffray","raw_affiliation_strings":["Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK","Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003180228","display_name":"Ricky D. Edmondson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1304557061","display_name":"National Center for Toxicological Research","ror":"https://ror.org/05jmhh281","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1304557061","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ricky D. Edmondson","raw_affiliation_strings":["National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, 72079, AR, USA","Current address: Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.,","National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, 72079, AR, USA","institution_ids":["https://openalex.org/I1304557061","https://openalex.org/I1320320070"]},{"raw_affiliation_string":"Current address: Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.,","institution_ids":["https://openalex.org/I79620101"]},{"raw_affiliation_string":"National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, USA","institution_ids":["https://openalex.org/I1304557061","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005595025","display_name":"Ronald T. Hay","orcid":"https://orcid.org/0000-0001-7113-9024","observed_orcids":["https://orcid.org/0000-0001-7113-9024"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ronald T. Hay","raw_affiliation_strings":["Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK","Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"Wellcome Trust Centre for Gene Regulation and Expression, Sir James Black Centre College of Life Sciences, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004435609","display_name":"Angeliki Malliri","orcid":"https://orcid.org/0000-0001-6848-090X","observed_orcids":["https://orcid.org/0000-0001-6848-090X"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Angeliki Malliri","raw_affiliation_strings":["Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, M20 4BX, UK","Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, M20 4BX, UK","institution_ids":["https://openalex.org/I28407311","https://openalex.org/I4210129527"]},{"raw_affiliation_string":"Cell Signalling Group, Cancer Research UK Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311","https://openalex.org/I4210129527"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5004435609"],"corresponding_institution_ids":["https://openalex.org/I28407311","https://openalex.org/I4210129527"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":5.7049,"has_fulltext":false,"cited_by_count":169,"citation_normalized_percentile":{"value":0.97350435,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"12","issue":"11","first_page":"1078","last_page":"1085"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.7271000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.7271000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.2551000118255615,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rac1","display_name":"Rac1","score":0.9470000267028809},{"id":"https://openalex.org/keywords/sumoylation","display_name":"SUMOylation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/pias3","display_name":"PIAS3","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hepatocyte-growth-factor","display_name":"hepatocyte growth factor","score":0.6700000166893005},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9369999766349792},{"id":"https://openalex.org/keywords/cell-invasion","display_name":"cell invasion","score":0.9430000185966492},{"id":"https://openalex.org/keywords/lamellipodia","display_name":"lamellipodia","score":0.8379999995231628},{"id":"https://openalex.org/keywords/rho-gtpase-activation","display_name":"Rho GTPase activation","score":0.7540000081062317},{"id":"https://openalex.org/keywords/polybasic-region","display_name":"polybasic region","score":0.7850000262260437},{"id":"https://openalex.org/keywords/ras-superfamily","display_name":"Ras superfamily","score":0.7049999833106995},{"id":"https://openalex.org/keywords/cytoskeletal-rearrangement","display_name":"cytoskeletal rearrangement","score":0.8880000114440918}],"concepts":[{"id":"https://openalex.org/C171350616","wikidata":"https://www.wikidata.org/wiki/Q61506","display_name":"SUMO protein","level":4,"score":0.9189063310623169},{"id":"https://openalex.org/C2779717556","wikidata":"https://www.wikidata.org/wiki/Q15325735","display_name":"RAC1","level":3,"score":0.8824581503868103},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7823628783226013},{"id":"https://openalex.org/C109185818","wikidata":"https://www.wikidata.org/wiki/Q3092607","display_name":"Lamellipodium","level":4,"score":0.5885095000267029},{"id":"https://openalex.org/C137738243","wikidata":"https://www.wikidata.org/wiki/Q189092","display_name":"Cell migration","level":3,"score":0.5870990753173828},{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.581223726272583},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.5769498348236084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.519180417060852},{"id":"https://openalex.org/C2780040266","wikidata":"https://www.wikidata.org/wiki/Q15311701","display_name":"CDC42","level":3,"score":0.5179982781410217},{"id":"https://openalex.org/C2780298669","wikidata":"https://www.wikidata.org/wiki/Q415071","display_name":"Small GTPase","level":3,"score":0.46849164366722107},{"id":"https://openalex.org/C2776879804","wikidata":"https://www.wikidata.org/wiki/Q7630919","display_name":"Subcellular localization","level":3,"score":0.4465031921863556},{"id":"https://openalex.org/C2909331102","wikidata":"https://www.wikidata.org/wiki/Q7278834","display_name":"Rac GTP-Binding Proteins","level":4,"score":0.42510920763015747},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.39262837171554565},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.36117398738861084},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.322078138589859},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.26596799492836},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1683015525341034},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.08307453989982605},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07473114132881165}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017228","descriptor_name":"Hepatocyte Growth Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019556","descriptor_name":"COS Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020830","descriptor_name":"rac1 GTP-Binding Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050828","descriptor_name":"Protein Inhibitors of Activated STAT","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058207","descriptor_name":"Sumoylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1038/ncb2112","doi":"https://doi.org/10.1038/ncb2112","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ncb2112","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},{"id":"pmid:20935639","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20935639","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire_cris_publications/e353245c-28c8-4a0b-b2d9-97894fadfefa","doi":null,"is_oa":false,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/e353245c-28c8-4a0b-b2d9-97894fadfefa","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Castillo-Lluva, S, Tatham, M H, Jones, R C, Jaffray, E G, Edmondson, R D, Hay, R T & Malliri, A 2010, 'SUMOylation of the GTPase Rac1 is required for optimal cell migration', Nature Cell Biology, vol. 12, no. 11, pp. 1078-U70. https://doi.org/10.1038/ncb2112","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2992316","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2992316","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Cell Biol","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.777.6983","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.777.6983","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/55/44/ukmss-32117.PMC2992316.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2992316","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2992316","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4157376355","display_name":null,"funder_award_id":"A6058","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G5123711645","display_name":null,"funder_award_id":"12937","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G8695588817","display_name":null,"funder_award_id":"C147/A6058","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"}],"funders":[{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W95252060","https://openalex.org/W1965596636","https://openalex.org/W1974667981","https://openalex.org/W1975357249","https://openalex.org/W1985462906","https://openalex.org/W1991008023","https://openalex.org/W1991366673","https://openalex.org/W1992577155","https://openalex.org/W1993180829","https://openalex.org/W2004220006","https://openalex.org/W2020527627","https://openalex.org/W2022052722","https://openalex.org/W2031874417","https://openalex.org/W2034261400","https://openalex.org/W2036164824","https://openalex.org/W2040916665","https://openalex.org/W2050895547","https://openalex.org/W2051795211","https://openalex.org/W2054806801","https://openalex.org/W2059494390","https://openalex.org/W2060073899","https://openalex.org/W2063575573","https://openalex.org/W2070270322","https://openalex.org/W2071199281","https://openalex.org/W2080752012","https://openalex.org/W2081190360","https://openalex.org/W2100866059","https://openalex.org/W2101778925","https://openalex.org/W2104746448","https://openalex.org/W2109137906","https://openalex.org/W2116988305","https://openalex.org/W2119301405","https://openalex.org/W2121779606","https://openalex.org/W2125768358","https://openalex.org/W2127371010","https://openalex.org/W2142055861","https://openalex.org/W2149290707","https://openalex.org/W2169346900"],"related_works":["https://openalex.org/W2005211103","https://openalex.org/W3006291327","https://openalex.org/W2376733108","https://openalex.org/W2139294293","https://openalex.org/W2057771459","https://openalex.org/W3147466400","https://openalex.org/W2009542532","https://openalex.org/W2887475084","https://openalex.org/W2609633876","https://openalex.org/W2166440966"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":19},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":27}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}