{"id":"https://openalex.org/W1994427320","doi":"https://doi.org/10.1016/0024-3205(85)90562-4","title":"Affinity chromatography for human Na+, K+-ATPase inhibitors in plasma and urine","display_name":"Affinity chromatography for human Na+, K+-ATPase inhibitors in plasma and urine","publication_year":1985,"publication_date":"1985-05-01","ids":{"openalex":"https://openalex.org/W1994427320","doi":"https://doi.org/10.1016/0024-3205(85)90562-4","mag":"1994427320","pmid":"https://pubmed.ncbi.nlm.nih.gov/2984510"},"language":"en","primary_location":{"id":"doi:10.1016/0024-3205(85)90562-4","doi":"https://doi.org/10.1016/0024-3205(85)90562-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0024-3205(85)90562-4","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016778313","display_name":"G Henning","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"G. Henning","raw_affiliation_strings":["INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111620203","display_name":"Jean\u2010Fran\u00e7ois Cloix","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"J.F. Cloix","raw_affiliation_strings":["INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073267357","display_name":"Irving W. Wainer","orcid":"https://orcid.org/0000-0003-1643-5845","observed_orcids":["https://orcid.org/0000-0003-1643-5845"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"I.W. Wainer","raw_affiliation_strings":["Division of Drug Chemistry, US Food and Drug Administration, Washington DC 20204, USA, now resident in INSERM U7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Drug Chemistry, US Food and Drug Administration, Washington DC 20204, USA, now resident in INSERM U7","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113732958","display_name":"Marie-Gabrielle Pernollet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M.G. Pernollet","raw_affiliation_strings":["INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110350408","display_name":"Marie\u2010Aude Devynck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M.A. Devynck","raw_affiliation_strings":["INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027593816","display_name":"Philippe Meyer","orcid":"https://orcid.org/0000-0002-2430-8953","observed_orcids":["https://orcid.org/0000-0002-2430-8953","https://orcid.org/0000-0002-3829-6631"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P. Meyer","raw_affiliation_strings":["INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U7, HOPITAL NECKER, 161 rue de S\u00e8vres, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5111620203"],"corresponding_institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":0.9078,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.72367682,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"18","first_page":"1787","last_page":"1798"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.8666999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.8666999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.04390000179409981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.018400000408291817,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/na-k-atpase-inhibitor","display_name":"Na+/K+-ATPase inhibitor","score":0.984000027179718},{"id":"https://openalex.org/keywords/affinity-chromatography","display_name":"affinity chromatography","score":0.8360000252723694},{"id":"https://openalex.org/keywords/endogenous-inhibitors","display_name":"endogenous inhibitors","score":0.5709999799728394},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.6660000085830688},{"id":"https://openalex.org/keywords/plasma","display_name":"plasma","score":0.7889999747276306},{"id":"https://openalex.org/keywords/urine","display_name":"urine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ouabain-binding","display_name":"ouabain binding","score":0.9010000228881836},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.8980000019073486},{"id":"https://openalex.org/keywords/enzyme-inhibition","display_name":"enzyme inhibition","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7667446136474609},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.7361953854560852},{"id":"https://openalex.org/C2779133857","wikidata":"https://www.wikidata.org/wiki/Q285911","display_name":"Ouabain","level":3,"score":0.6767190098762512},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.67603600025177},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5733105540275574},{"id":"https://openalex.org/C179247698","wikidata":"https://www.wikidata.org/wiki/Q382799","display_name":"Affinity chromatography","level":3,"score":0.5635831952095032},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5285521745681763},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.5141878128051758},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.49383124709129333},{"id":"https://openalex.org/C2776980637","wikidata":"https://www.wikidata.org/wiki/Q427492","display_name":"Enzyme inhibitor","level":3,"score":0.45946359634399414},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2536851167678833},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.22810965776443481},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003429","descriptor_name":"Cross Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004077","descriptor_name":"Digoxin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004800","descriptor_name":"Enzymes, Immobilized","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010042","descriptor_name":"Ouabain","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011955","descriptor_name":"Receptors, Drug","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0024-3205(85)90562-4","doi":"https://doi.org/10.1016/0024-3205(85)90562-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0024-3205(85)90562-4","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},{"id":"pmid:2984510","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2984510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1540146572","https://openalex.org/W1870554052","https://openalex.org/W1970260922","https://openalex.org/W1979780428","https://openalex.org/W1983649348","https://openalex.org/W1987864951","https://openalex.org/W2033542908","https://openalex.org/W2034711325","https://openalex.org/W2036472952","https://openalex.org/W2048887457","https://openalex.org/W2068850000","https://openalex.org/W2070842387","https://openalex.org/W2078044385","https://openalex.org/W2290750774","https://openalex.org/W2297542821","https://openalex.org/W2338626728","https://openalex.org/W2395249929","https://openalex.org/W3165208394"],"related_works":["https://openalex.org/W2409058176","https://openalex.org/W2439794445","https://openalex.org/W1989980850","https://openalex.org/W2022336758","https://openalex.org/W2020658206","https://openalex.org/W1999393856","https://openalex.org/W1995496851","https://openalex.org/W2466493610","https://openalex.org/W2073899061","https://openalex.org/W2464123718"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}