{"id":"https://openalex.org/W1994351932","doi":"https://doi.org/10.1164/ajrccm/143.4_pt_1.834","title":"Alveolar Macrophage Migration after Lung Transplantation","display_name":"Alveolar Macrophage Migration after Lung Transplantation","publication_year":1991,"publication_date":"1991-04-01","ids":{"openalex":"https://openalex.org/W1994351932","doi":"https://doi.org/10.1164/ajrccm/143.4_pt_1.834","mag":"1994351932","pmid":"https://pubmed.ncbi.nlm.nih.gov/2008994"},"language":"en","primary_location":{"id":"doi:10.1164/ajrccm/143.4_pt_1.834","doi":"https://doi.org/10.1164/ajrccm/143.4_pt_1.834","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm/143.4_pt_1.834","pdf_url":null,"source":{"id":"https://openalex.org/S2751726451","display_name":"American Review of Respiratory Disease","issn_l":"0003-0805","issn":["0003-0805","2376-3752"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Review of Respiratory Disease","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Robert M. Hoffman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Hoffman","raw_affiliation_strings":["Department of Medicine, University of Pittsburgh, School of Medicine, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Pittsburgh, School of Medicine, Pennsylvania","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002906339","display_name":"James H. Dauber","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James H. Dauber","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069464445","display_name":"Irvin L. Paradis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irvin L. Paradis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058363405","display_name":"Bartley P. Griffith","orcid":"https://orcid.org/0000-0003-3015-9322","observed_orcids":["https://orcid.org/0000-0003-3015-9322"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bartley P. Griffith","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5030627984","display_name":"Robert L. Hardesty","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert L. Hardesty","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9029,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.84540298,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"143","issue":"4_Part_1","first_page":"834","last_page":"838"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alveolar-macrophages","display_name":"alveolar macrophages","score":0.9769999980926514},{"id":"https://openalex.org/keywords/macrophage-migration","display_name":"macrophage migration","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lung-transplantation","display_name":"lung transplantation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/chronic-rejection","display_name":"chronic rejection","score":0.5649999976158142},{"id":"https://openalex.org/keywords/pneumocystis-jirovecii-pneumonia","display_name":"Pneumocystis carinii pneumonia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/pulmonary-infection","display_name":"pulmonary infection","score":0.925000011920929},{"id":"https://openalex.org/keywords/pulmonary-host-defense","display_name":"pulmonary host defense","score":0.6890000104904175},{"id":"https://openalex.org/keywords/bronchoalveolar-lavage","display_name":"bronchoalveolar lavage","score":0.8799999952316284},{"id":"https://openalex.org/keywords/macrophage-activation","display_name":"macrophage activation","score":0.8640000224113464}],"concepts":[{"id":"https://openalex.org/C2781448352","wikidata":"https://www.wikidata.org/wiki/Q1637912","display_name":"Lung transplantation","level":3,"score":0.6151862740516663},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6038969159126282},{"id":"https://openalex.org/C2778012055","wikidata":"https://www.wikidata.org/wiki/Q448687","display_name":"Alveolar macrophage","level":4,"score":0.5526524186134338},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5221012830734253},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4887125492095947},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48211240768432617},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3900185823440552},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25117582082748413},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14177408814430237},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001992","descriptor_name":"Bronchoalveolar Lavage Fluid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004151","descriptor_name":"Dipeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011020","descriptor_name":"Pneumonia, Pneumocystis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011650","descriptor_name":"Pulmonary Alveoli","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D011650","descriptor_name":"Pulmonary Alveoli","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016040","descriptor_name":"Lung Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1164/ajrccm/143.4_pt_1.834","doi":"https://doi.org/10.1164/ajrccm/143.4_pt_1.834","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm/143.4_pt_1.834","pdf_url":null,"source":{"id":"https://openalex.org/S2751726451","display_name":"American Review of Respiratory Disease","issn_l":"0003-0805","issn":["0003-0805","2376-3752"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Review of Respiratory Disease","raw_type":"journal-article"},{"id":"pmid:2008994","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2008994","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American review of respiratory disease","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G5033209030","display_name":null,"funder_award_id":"HL 37533","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8256561361","display_name":"MODULATION OF ALVEOLAR MACROPHAGE FUNCTION BY SURFACTANT","funder_award_id":"K08HL001367","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1993105282","https://openalex.org/W1995520236","https://openalex.org/W1999448121","https://openalex.org/W2005337929","https://openalex.org/W2010889750","https://openalex.org/W2018325697","https://openalex.org/W2020706552","https://openalex.org/W2039205268","https://openalex.org/W2085751093"],"related_works":["https://openalex.org/W2070889171","https://openalex.org/W2044986589","https://openalex.org/W3195685845","https://openalex.org/W2922002568","https://openalex.org/W2531435723","https://openalex.org/W2132114084","https://openalex.org/W2067548550","https://openalex.org/W2066278050","https://openalex.org/W2146447766","https://openalex.org/W2338440352"],"abstract_inverted_index":{"Pulmonary":[0],"infection":[1,73,220],"is":[2,209,224],"a":[3,44,98,115],"major":[4],"source":[5],"of":[6,12,43,66,72,79,118,143,158,165,219,230],"morbidity":[7],"and":[8,26,38,97,114,137,175,223,237],"mortality":[9],"in":[10,22,40,51,149,170,188,197,212,225],"recipients":[11,57,67,147,169,215],"lung":[13,55,213],"allografts.":[14],"The":[15,61],"alveolar":[16,206],"macrophage":[17,207,232],"plays":[18],"an":[19,88],"important":[20],"role":[21,30],"pulmonary":[23],"host":[24],"defense,":[25],"to":[27,36,135,156],"fulfill":[28],"this":[29],"it":[31,199],"must":[32],"have":[33],"the":[34,41,77,150,171],"ability":[35],"orient":[37],"migrate":[39],"direction":[42],"stimulus.":[45],"Thus":[46],"migratory":[47,133],"activity":[48],"was":[49,154,180,186,200],"measured":[50],"cells":[52,144,166],"recovered":[53,126],"from":[54,145,167],"transplant":[56],"by":[58,127],"bronchoalveolar":[59,80,128],"lavage.":[60,81],"primary":[62],"patient":[63],"group":[64,91,101,117],"consisted":[65],"who":[68],"had":[69],"no":[70],"evidence":[71],"or":[74,221],"rejection":[75,113,179,222],"at":[76],"time":[78],"These":[82],"patients":[83,110,119],"were":[84,130],"further":[85],"subdivided":[86],"into":[87],"early":[89,172],"postoperative":[90,100,152,173],"(less":[92],"than":[93,103,182],"6":[94,104],"wk":[95,105],"posttransplant)":[96],"late":[99,151],"(greater":[102],"posttransplant).":[106],"Other":[107],"categories":[108],"included":[109],"with":[111,120,193],"chronic":[112,178,239],"small":[116],"Pneumocystis":[121],"carinii":[122,195],"pneumonia.":[123],"Alveolar":[124],"macrophages":[125],"lavage":[129],"assayed":[131],"for":[132],"response":[134],"N-formylmethlonylphenylalanine":[136],"endotoxin-activated":[138],"human":[139],"serum.":[140],"Stimulated":[141],"migration":[142,164,185,208],"healthy":[146,168],"obtained":[148],"course":[153],"similar":[155,187],"that":[157,205],"normal":[159],"control":[160],"subjects,":[161],"but":[162],"stimulated":[163],"period":[174],"those":[176,192],"undergoing":[177],"greater":[181],"expected.":[183],"Spontaneous":[184],"all":[189],"groups":[190],"except":[191],"P.":[194],"pneumonia,":[196],"whom":[198],"greatly":[201],"increased.":[202],"We":[203],"conclude":[204],"not":[210],"impaired":[211],"allograft":[214],"without":[216],"apparent":[217],"signs":[218],"fact":[226],"increased":[227],"during":[228,238],"periods":[229],"possible":[231],"activation":[233],"(shortly":[234],"after":[235],"transplantation":[236],"rejection).":[240]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}