{"id":"https://openalex.org/W1993920","doi":null,"title":"Three-dimensional in-vivo dimensions of 'He's triangle' during acute left ventricular ischemia.","display_name":"Three-dimensional in-vivo dimensions of 'He's triangle' during acute left ventricular ischemia.","publication_year":2001,"publication_date":"2001-11-01","ids":{"openalex":"https://openalex.org/W1993920","mag":"1993920","pmid":"https://pubmed.ncbi.nlm.nih.gov/11767184"},"language":"en","primary_location":{"id":"pmid:11767184","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11767184","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart valve disease","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103538257","display_name":"David T. M. Lai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D T Lai","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Stanford University School of Medicine, California 94305-5247, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Stanford University School of Medicine, California 94305-5247, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055439627","display_name":"Frederick A. Tibayan","orcid":"https://orcid.org/0000-0002-8840-9737","observed_orcids":["https://orcid.org/0000-0002-8840-9737"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F A Tibayan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066275079","display_name":"Tomasz A. Timek","orcid":"https://orcid.org/0000-0001-8792-4756","observed_orcids":["https://orcid.org/0000-0001-8792-4756"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T A Timek","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066885001","display_name":"David H. Liang","orcid":"https://orcid.org/0000-0002-7343-7583","observed_orcids":["https://orcid.org/0000-0002-7343-7583"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Liang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062621509","display_name":"George T. Daughters","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G T Daughters","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051763281","display_name":"Neil B. Ingels","orcid":"https://orcid.org/0009-0001-6180-610X","observed_orcids":["https://orcid.org/0009-0001-6180-610X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N B Ingels","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5028109655","display_name":"David Craig Miller","orcid":"https://orcid.org/0000-0001-7619-0080","observed_orcids":["https://orcid.org/0000-0001-7619-0080"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D C Miller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2437,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.61737106,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"10","issue":"6","first_page":"767","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12598","display_name":"Cardiac Structural Anomalies and Repair","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ischemic-mitral-regurgitation","display_name":"ischemic mitral regurgitation","score":0.9150000214576721},{"id":"https://openalex.org/keywords/chordae-tendineae","display_name":"chordae tendineae","score":0.8830000162124634},{"id":"https://openalex.org/keywords/mitral-annulus","display_name":"mitral annulus","score":0.746999979019165},{"id":"https://openalex.org/keywords/papillary-muscle","display_name":"papillary muscle","score":0.7739999890327454},{"id":"https://openalex.org/keywords/circumflex-coronary-artery-occlusion","display_name":"circumflex coronary artery occlusion","score":0.9079999923706055},{"id":"https://openalex.org/keywords/sheep-model","display_name":"sheep model","score":0.7889999747276306}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8084702491760254},{"id":"https://openalex.org/C2780870192","wikidata":"https://www.wikidata.org/wiki/Q1076385","display_name":"Chordae tendineae","level":3,"score":0.7948319911956787},{"id":"https://openalex.org/C2777543888","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral valve","level":2,"score":0.5957716107368469},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5881794095039368},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5378469824790955},{"id":"https://openalex.org/C150936888","wikidata":"https://www.wikidata.org/wiki/Q4769748","display_name":"Annulus (botany)","level":2,"score":0.49720504879951477},{"id":"https://openalex.org/C197321550","wikidata":"https://www.wikidata.org/wiki/Q11175","display_name":"Circumflex","level":3,"score":0.49540555477142334},{"id":"https://openalex.org/C2777274916","wikidata":"https://www.wikidata.org/wiki/Q1913658","display_name":"Papillary muscle","level":2,"score":0.4902346730232239},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47710663080215454},{"id":"https://openalex.org/C2776659728","wikidata":"https://www.wikidata.org/wiki/Q887004","display_name":"Leaflet (botany)","level":2,"score":0.46970030665397644},{"id":"https://openalex.org/C2993373945","wikidata":"https://www.wikidata.org/wiki/Q268292","display_name":"Mitral regurgitation","level":2,"score":0.44781941175460815},{"id":"https://openalex.org/C2777728562","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral annulus","level":4,"score":0.4316829442977905},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.38060224056243896},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.10553902387619019},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.09181609749794006},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05919760465621948},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002815","descriptor_name":"Chordae Tendineae","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002815","descriptor_name":"Chordae Tendineae","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008943","descriptor_name":"Mitral Valve","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008943","descriptor_name":"Mitral Valve","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010210","descriptor_name":"Papillary Muscles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D010210","descriptor_name":"Papillary Muscles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D018487","descriptor_name":"Ventricular Dysfunction, Left","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D018487","descriptor_name":"Ventricular Dysfunction, Left","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018487","descriptor_name":"Ventricular Dysfunction, Left","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:11767184","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11767184","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart valve disease","raw_type":"Journal Article"},{"id":"mag:1993920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11767184","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2936114015","display_name":"ALFIERI VALVE REPAIR IN ISCHEMIC MITRAL REGURGITATION","funder_award_id":"1f32hl010452-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5163098803","display_name":"Ventricular Dynamics from Surgically Inserted Markers","funder_award_id":"R01HL029589","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2127172910","https://openalex.org/W1976269561","https://openalex.org/W1997961441","https://openalex.org/W2051843936","https://openalex.org/W2160213609","https://openalex.org/W2099092620","https://openalex.org/W1508558919","https://openalex.org/W2035223363","https://openalex.org/W2889118921","https://openalex.org/W3112282612"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"AIM":[2],"OF":[3],"THE":[4],"STUDY:":[5],"Changes":[6],"in":[7,27,61,220],"the":[8,66,82,96,105,113,126,131,199,221,228,231,250,260,269,287],"dimensions":[9],"of":[10,47,75,174,223,230,252,289],"'He's":[11],"triangle'":[12],"(formed":[13],"by":[14,163,187,205],"mitral":[15,29,41,67,84,115,159,292],"leaflet":[16,42,85,116,169,201],"segments":[17,170],"subtending":[18],"two":[19],"associated":[20],"chordae":[21,92],"tendineae)":[22],"derived":[23],"from":[24,95,104,122,212],"data":[25],"obtained":[26],"in-vitro":[28],"valve":[30],"models":[31],"have":[32,51],"been":[33,53],"proposed":[34],"to":[35,64,157,182,185,203,226],"provide":[36,283],"a":[37,213],"mechanistic":[38],"explanation":[39],"for":[40],"malcoaptation.":[43],"The":[44,179],"in-vivo":[45],"dynamics":[46],"He's":[48,77,176],"triangle,":[49],"however,":[50],"not":[52,266,297],"hitherto":[54],"determined.":[55],"METHODS:":[56],"Radio-opaque":[57],"markers":[58],"were":[59,147,265],"placed":[60],"13":[62],"sheep":[63],"delineate":[65],"annulus":[68],"and":[69,89,111,119,136,150,184,192,198,235,254,262,271],"four":[70],"(of":[71],"an":[72],"infinite":[73],"number":[74],"possible)":[76],"triangles":[78,177],"formed":[79],"by:":[80],"(i)":[81],"anterior":[83,97,127],"(AML),":[86],"first-":[87],"(CT1)":[88],"second-order":[90],"(CT2)":[91],"tendineae":[93],"emanating":[94,121],"papillary":[98,107,133],"tip":[99,108],"(APT1)":[100],"as":[101,103,128,130,161,268],"well":[102,129],"posterior":[106,114,132,200],"(PPT1),":[109],"respectively;":[110],"(ii)":[112],"(PML),":[117],"CT1":[118,234,253],"CT2":[120,224,236,255],"other":[123,233],"loci":[124],"on":[125],"tips":[134],"(APT2":[135],"PPT2),":[137],"respectively.":[138],"Immediately":[139],"postoperatively":[140],"(anesthetized,":[141],"open-chest),":[142],"three-dimensional":[143],"end-systolic":[144],"marker":[145],"positions":[146],"measured":[148],"before":[149],"during":[151,240,274],"circumflex":[152],"coronary":[153],"artery":[154],"occlusion":[155],"sufficient":[156],"produce":[158],"regurgitation,":[160,293],"verified":[162],"echocardiography.":[164],"RESULTS:":[165],"During":[166],"ischemia,":[167,249],"three":[168,175],"constituting":[171],"one":[172],"side":[173],"elongated:":[178],"AML":[180,261,270],"attached":[181,202,225],"APT1":[183],"PPT1":[186],"1.5+/-1.2":[188],"mm":[189,194,207,215],"(p":[190,195,208,216],"<0.001)":[191],"1.3+/-0.8":[193],"<0.001),":[196],"respectively,":[197],"APT2":[204],"1.4+/-1.9":[206],"=":[209,217],"0.02).":[210],"Apart":[211],"0.9+/-1.1":[214],"0.02)":[218],"increase":[219],"length":[222,229],"APT2,":[227],"seven":[232],"remained":[237,256],"relatively":[238,257],"unchanged":[239],"acute":[241,247,275,290],"left":[242,276],"ventricular":[243,277],"ischemia.":[244,278],"CONCLUSION:":[245],"With":[246],"posterolateral":[248],"lengths":[251,264],"constant,":[258],"but":[259],"PML":[263,272],"constant":[267],"'unfurled'":[273],"These":[279],"geometric":[280],"changes":[281],"may":[282],"further":[284],"insight":[285],"into":[286],"mechanisms":[288],"ischemic":[291],"though":[294],"it":[295],"is":[296],"clear":[298],"how":[299],"they":[300],"will":[301],"be":[302],"clinically":[303],"helpful.":[304]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}