{"id":"https://openalex.org/W1993785609","doi":"https://doi.org/10.1016/j.chembiol.2005.06.004","title":"Chemical Biology: Innovative Solutions for Diverse Challenges","display_name":"Chemical Biology: Innovative Solutions for Diverse Challenges","publication_year":2005,"publication_date":"2005-06-01","ids":{"openalex":"https://openalex.org/W1993785609","doi":"https://doi.org/10.1016/j.chembiol.2005.06.004","mag":"1993785609","pmid":"https://pubmed.ncbi.nlm.nih.gov/16089012"},"language":"en","primary_location":{"id":"doi:10.1016/j.chembiol.2005.06.004","doi":"https://doi.org/10.1016/j.chembiol.2005.06.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chembiol.2005.06.004","pdf_url":"http://www.cell.com/article/S1074552105001705/pdf","source":{"id":"https://openalex.org/S85134406","display_name":"Chemistry & Biology","issn_l":"1074-5521","issn":["1074-5521","1879-1301"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry & Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1074552105001705/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049845345","display_name":"Joshua A. Kritzer","orcid":"https://orcid.org/0000-0003-2878-6781","observed_orcids":["https://orcid.org/0000-0003-2878-6781"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joshua A. Kritzer","raw_affiliation_strings":["Departmernt of Chemistry, Yale University, New Haven, CT 06510, USA. joshua.kritzer@gmail.com","Department of Chemistry, Yale University, New Haven, Connecticut 06510"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departmernt of Chemistry, Yale University, New Haven, CT 06510, USA. joshua.kritzer@gmail.com","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Chemistry, Yale University, New Haven, Connecticut 06510","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006573975","display_name":"Nathan W. Luedtke","orcid":"https://orcid.org/0000-0003-2214-8818","observed_orcids":["https://orcid.org/0000-0003-2214-8818"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nathan W. Luedtke","raw_affiliation_strings":["Department of Chemistry, Yale University, New Haven, Connecticut 06510"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Yale University, New Haven, Connecticut 06510","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5006573975","https://openalex.org/A5049845345"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.08200474,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"12","issue":"6","first_page":"617","last_page":"620"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11440","display_name":"Click Chemistry and Applications","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11440","display_name":"Click Chemistry and Applications","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemical-biology","display_name":"chemical biology","score":0.9890000224113464},{"id":"https://openalex.org/keywords/glycobiology","display_name":"glycobiology","score":0.9950000047683716},{"id":"https://openalex.org/keywords/neurochemistry","display_name":"neurochemistry","score":0.9980000257492065},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":1.0},{"id":"https://openalex.org/keywords/molecular-biophysics","display_name":"molecular biophysics","score":0.9959999918937683},{"id":"https://openalex.org/keywords/molecular-genetics","display_name":"molecular genetics","score":0.8519999980926514},{"id":"https://openalex.org/keywords/chemistry-biology-interface","display_name":"chemistry-biology interface","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C204641814","wikidata":"https://www.wikidata.org/wiki/Q899224","display_name":"Glycobiology","level":4,"score":0.6510559320449829},{"id":"https://openalex.org/C2779182362","wikidata":"https://www.wikidata.org/wiki/Q17126187","display_name":"Session (web analytics)","level":2,"score":0.44770529866218567},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4049246907234192},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.3969435691833496},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.21457475423812866},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14782825112342834},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.0},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.0},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001671","descriptor_name":"Biochemistry","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.chembiol.2005.06.004","doi":"https://doi.org/10.1016/j.chembiol.2005.06.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chembiol.2005.06.004","pdf_url":"http://www.cell.com/article/S1074552105001705/pdf","source":{"id":"https://openalex.org/S85134406","display_name":"Chemistry & Biology","issn_l":"1074-5521","issn":["1074-5521","1879-1301"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry & Biology","raw_type":"journal-article"},{"id":"pmid:16089012","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16089012","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry & biology","raw_type":"Conference Proceedings"}],"best_oa_location":{"id":"doi:10.1016/j.chembiol.2005.06.004","doi":"https://doi.org/10.1016/j.chembiol.2005.06.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chembiol.2005.06.004","pdf_url":"http://www.cell.com/article/S1074552105001705/pdf","source":{"id":"https://openalex.org/S85134406","display_name":"Chemistry & Biology","issn_l":"1074-5521","issn":["1074-5521","1879-1301"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry & Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G39097371","display_name":"Assembly of Hydrolytic PeptideMetalloPorphyrin Complexes","funder_award_id":"F32GM074401","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6648410961","display_name":null,"funder_award_id":"GM074401","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1993785609.pdf","grobid_xml":"https://content.openalex.org/works/W1993785609.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1581075644","https://openalex.org/W1964493422","https://openalex.org/W1972708527","https://openalex.org/W1981659539","https://openalex.org/W1994477951","https://openalex.org/W1995273612","https://openalex.org/W2004125187","https://openalex.org/W2007110714","https://openalex.org/W2049105226","https://openalex.org/W2060497666","https://openalex.org/W2065770997","https://openalex.org/W2066580507","https://openalex.org/W2067810191","https://openalex.org/W2068931555","https://openalex.org/W2069165607","https://openalex.org/W2080550406","https://openalex.org/W2082715212","https://openalex.org/W2083261792","https://openalex.org/W2101362932","https://openalex.org/W2148592148","https://openalex.org/W2153461732"],"related_works":["https://openalex.org/W2782018836","https://openalex.org/W2067038819","https://openalex.org/W2081594847","https://openalex.org/W2077235945","https://openalex.org/W1986295987","https://openalex.org/W4239179892","https://openalex.org/W7098384095","https://openalex.org/W2601466004","https://openalex.org/W1967711913","https://openalex.org/W1966511399"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}