{"id":"https://openalex.org/W1993669504","doi":"https://doi.org/10.1016/s0168-8278(11)60469-8","title":"467 LONGTERM BENEFITS OF SUSTAINED VIROLOGICAL RESPONSE (SVR) IN PATIENTS WITH CHRONIC HEPATITIS C (CHC) VIRUS INFECTION: THE GERMAN LOTOS STUDY","display_name":"467 LONGTERM BENEFITS OF SUSTAINED VIROLOGICAL RESPONSE (SVR) IN PATIENTS WITH CHRONIC HEPATITIS C (CHC) VIRUS INFECTION: THE GERMAN LOTOS STUDY","publication_year":2011,"publication_date":"2011-03-01","ids":{"openalex":"https://openalex.org/W1993669504","doi":"https://doi.org/10.1016/s0168-8278(11)60469-8","mag":"1993669504"},"language":"en","primary_location":{"id":"doi:10.1016/s0168-8278(11)60469-8","doi":"https://doi.org/10.1016/s0168-8278(11)60469-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-8278(11)60469-8","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"J. Reimer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["DE","US"],"is_corresponding":true,"raw_author_name":"J. Reimer","raw_affiliation_strings":["Center for Interdisciplinary Addiction Research, University of Hamburg, Hamburg,","University of Pennsylvania, Philadelphia, PA, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Interdisciplinary Addiction Research, University of Hamburg, Hamburg,","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"University of Pennsylvania, Philadelphia, PA, USA;","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068787709","display_name":"Dietrich Hueppe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150268","display_name":"Azienda Ospedaliera Fatebenefratelli e Oftalmico","ror":"https://ror.org/05v558c44","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210150268","https://openalex.org/I4210156709"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D. Hueppe","raw_affiliation_strings":["A.O. Fatebenefratelli e Oftalmico, Milan, Italy;","Center of Gastroenterology, Herne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"A.O. Fatebenefratelli e Oftalmico, Milan, Italy;","institution_ids":["https://openalex.org/I4210150268"]},{"raw_affiliation_string":"Center of Gastroenterology, Herne,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015656005","display_name":"Petra Sandow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Sandow","raw_affiliation_strings":["General Practice, Berlin, 4 General Practice, 14057, Berlin,","University of California Davis, Sacramento, CA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Practice, Berlin, 4 General Practice, 14057, Berlin,","institution_ids":[]},{"raw_affiliation_string":"University of California Davis, Sacramento, CA,","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":null,"display_name":"U. Naumann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U. Naumann","raw_affiliation_strings":["Digestive Disease Associates, Baltimore, MD,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Digestive Disease Associates, Baltimore, MD,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026330597","display_name":"Joerg Goelz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Goelz","raw_affiliation_strings":["Digestive Disease Associates, Baltimore, MD,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Digestive Disease Associates, Baltimore, MD,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111879644","display_name":"Stefan Christensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]},{"id":"https://openalex.org/I4210122132","display_name":"Kaiser Permanente Sacramento Medical Center","ror":"https://ror.org/02q404g62","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4210122132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Christensen","raw_affiliation_strings":["Center for Interdisciplinary Medicine (CIM), Muenster,","Kaiser Permanente, Sacramento, CA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Interdisciplinary Medicine (CIM), Muenster,","institution_ids":[]},{"raw_affiliation_string":"Kaiser Permanente, Sacramento, CA,","institution_ids":["https://openalex.org/I1343052199","https://openalex.org/I4210122132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003023703","display_name":"HW Busch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]},{"id":"https://openalex.org/I4210122132","display_name":"Kaiser Permanente Sacramento Medical Center","ror":"https://ror.org/02q404g62","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4210122132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Busch","raw_affiliation_strings":["Center for Interdisciplinary Medicine (CIM), Muenster,","Kaiser Permanente, Sacramento, CA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Interdisciplinary Medicine (CIM), Muenster,","institution_ids":[]},{"raw_affiliation_string":"Kaiser Permanente, Sacramento, CA,","institution_ids":["https://openalex.org/I1343052199","https://openalex.org/I4210122132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033488471","display_name":"Tracey Lutz","orcid":"https://orcid.org/0000-0001-9986-288X","observed_orcids":["https://orcid.org/0000-0001-9986-288X"]},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. Lutz","raw_affiliation_strings":["Infektiologikum, Frankfurt,","Merck, Whitehouse Station, NJ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infektiologikum, Frankfurt,","institution_ids":[]},{"raw_affiliation_string":"Merck, Whitehouse Station, NJ,","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065798573","display_name":"KH Hey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I206945453","display_name":"Paderborn University","ror":"https://ror.org/058kzsd48","country_code":"DE","type":"education","lineage":["https://openalex.org/I206945453"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"K.-H. Hey","raw_affiliation_strings":["Cedars-Sinai Medical Center, Los Angeles, CA,","Center of Gastroenterology, Paderborn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Los Angeles, CA,","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"Center of Gastroenterology, Paderborn,","institution_ids":["https://openalex.org/I206945453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054059032","display_name":"Kurt Gr\u00fcngreiff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107249","display_name":"Klinikum Magdeburg","ror":"https://ror.org/01trdns33","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210107249"]},{"id":"https://openalex.org/I4210138551","display_name":"University Hospital Magdeburg","ror":"https://ror.org/03m04df46","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138551"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"K. Gruengreiff","raw_affiliation_strings":["Center of Gastroenterology, Magdeburg,","Weill Cornell Medical College, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Gastroenterology, Magdeburg,","institution_ids":["https://openalex.org/I4210107249","https://openalex.org/I4210138551"]},{"raw_affiliation_string":"Weill Cornell Medical College, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084906166","display_name":"M. Leuschner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Leuschner","raw_affiliation_strings":["Center of Internal Medicine, Offenbach,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Internal Medicine, Offenbach,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010968974","display_name":"G. Feiten","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Feiten","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058697669","display_name":"Bernd Bokemeyer","orcid":"https://orcid.org/0000-0003-2016-6991","observed_orcids":["https://orcid.org/0000-0003-2016-6991"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Bokemeyer","raw_affiliation_strings":["Gastroenterology Practice, Minden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Practice, Minden,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"G. Bellmann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Bellmann","raw_affiliation_strings":["General Practice, Berlin,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Practice, Berlin,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111226119","display_name":"R. Link","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103230","display_name":"St. Josefs Hospital","ror":"https://ror.org/019jjbt65","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210103230"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Link","raw_affiliation_strings":["Clinic for Internal Medicine, St. Josefs Hospital, Offenburg,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic for Internal Medicine, St. Josefs Hospital, Offenburg,","institution_ids":["https://openalex.org/I4210103230"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S. Stoll","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094361","display_name":"Roche Pharma AG (Germany)","ror":"https://ror.org/00sh68184","country_code":"DE","type":"company","lineage":["https://openalex.org/I118019719","https://openalex.org/I4210094361"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S. Stoll","raw_affiliation_strings":["Roche Pharma AG, Grenzach-Wyhlen,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roche Pharma AG, Grenzach-Wyhlen,","institution_ids":["https://openalex.org/I4210094361"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076739762","display_name":"Heiner H. Wedemeyer","orcid":"https://orcid.org/0000-0003-2906-0480","observed_orcids":["https://orcid.org/0000-0003-2906-0480"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Wedemeyer","raw_affiliation_strings":["Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":15,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I159176309","https://openalex.org/I79576946"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12972564,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"54","issue":null,"first_page":"S190","last_page":"S191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-hepatitis-c","display_name":"chronic hepatitis C","score":0.875},{"id":"https://openalex.org/keywords/sustained-virologic-response","display_name":"sustained virological response","score":0.8479999899864197},{"id":"https://openalex.org/keywords/end-stage-liver-disease","display_name":"end-stage liver disease","score":0.8700000047683716},{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.8080000281333923},{"id":"https://openalex.org/keywords/hepatitis-c-cirrhosis","display_name":"hepatitis C cirrhosis","score":0.6949999928474426},{"id":"https://openalex.org/keywords/pegylated-interferon","display_name":"pegylated interferon","score":0.8669999837875366},{"id":"https://openalex.org/keywords/ribavirin","display_name":"ribavirin","score":0.996999979019165},{"id":"https://openalex.org/keywords/treatment-tolerability","display_name":"treatment tolerability","score":0.5820000171661377},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.8830000162124634},{"id":"https://openalex.org/keywords/hcv-genotype-1","display_name":"HCV genotype 1","score":0.48399999737739563},{"id":"https://openalex.org/keywords/hcv-genotype-2","display_name":"HCV genotype 2","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7444540858268738},{"id":"https://openalex.org/C3020491458","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Chronic hepatitis","level":3,"score":0.6410291790962219},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5203599333763123},{"id":"https://openalex.org/C154775046","wikidata":"https://www.wikidata.org/wiki/Q188","display_name":"German","level":2,"score":0.5046077966690063},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4652579426765442},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3722239136695862},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.28592246770858765},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.03209218382835388},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0168-8278(11)60469-8","doi":"https://doi.org/10.1016/s0168-8278(11)60469-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-8278(11)60469-8","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2151923609","https://openalex.org/W2018184286","https://openalex.org/W2165992348","https://openalex.org/W2061557715","https://openalex.org/W1656352885","https://openalex.org/W2091909917","https://openalex.org/W138599064","https://openalex.org/W1641858867","https://openalex.org/W2075413457","https://openalex.org/W1549683299"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}