{"id":"https://openalex.org/W1993472010","doi":"https://doi.org/10.1159/000320106","title":"Homocysteine Levels in Patients with Heart Failure with Preserved Ejection Fraction","display_name":"Homocysteine Levels in Patients with Heart Failure with Preserved Ejection Fraction","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1993472010","doi":"https://doi.org/10.1159/000320106","mag":"1993472010","pmid":"https://pubmed.ncbi.nlm.nih.gov/20881390"},"language":"en","primary_location":{"id":"doi:10.1159/000320106","doi":"https://doi.org/10.1159/000320106","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000320106","pdf_url":null,"source":{"id":"https://openalex.org/S4210184113","display_name":"Cardiology","issn_l":"0008-6312","issn":["0008-6312","1421-9751"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1993472010"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033776345","display_name":"Ertu\u011frul Okuyan","orcid":"https://orcid.org/0000-0002-0626-2939","observed_orcids":["https://orcid.org/0000-0002-0626-2939"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ertu\u011frul Okuyan","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul, Turkey. dreokuyan@hotmail.com","Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul, Turkey. dreokuyan@hotmail.com","institution_ids":["https://openalex.org/I4210112601"]},{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027833021","display_name":"Ahmet Uslu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmet Uslu","raw_affiliation_strings":["Serife Baci State Hospital, Kastamonu, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Serife Baci State Hospital, Kastamonu, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102913718","display_name":"Mehmet Akif \u00c7akar","orcid":"https://orcid.org/0000-0003-3216-4205","observed_orcids":["https://orcid.org/0000-0003-3216-4205"]},"institutions":[{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehmet Akif \u00c7akar","raw_affiliation_strings":["Sakarya Education and Research Hospital, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sakarya Education and Research Hospital, Sakarya, Turkey","institution_ids":["https://openalex.org/I4210116985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058129889","display_name":"\u0130rfan \u015eahin","orcid":"https://orcid.org/0000-0001-9165-7566","observed_orcids":["https://orcid.org/0000-0001-9165-7566"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Irfan Sahin","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103711484","display_name":"\u0130mran \u00d6n\u00fcr","orcid":"https://orcid.org/0000-0002-0105-361X","observed_orcids":["https://orcid.org/0000-0002-0105-361X"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Imran \u00d6n\u00fcr","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004976284","display_name":"As\u0131m Enho\u015f","orcid":"https://orcid.org/0000-0002-7479-7783","observed_orcids":["https://orcid.org/0000-0002-7479-7783"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"As\u0131m Enhos","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045675408","display_name":"Halil \u0130brahim Biter","orcid":"https://orcid.org/0000-0002-5355-6729","observed_orcids":["https://orcid.org/0000-0002-5355-6729","https://orcid.org/0000-0002-5085-7980"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Halil Ibrahim Biter","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072345305","display_name":"\u015e\u00fckr\u00fc \u00c7etin","orcid":"https://orcid.org/0000-0001-5718-4988","observed_orcids":["https://orcid.org/0000-0001-5718-4988"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u015e\u00fckr\u00fc \u00c7etin","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102910410","display_name":"Mustafa Hakan Din\u00e7kal","orcid":"https://orcid.org/0000-0002-3497-4490","observed_orcids":["https://orcid.org/0000-0002-3497-4490"]},"institutions":[{"id":"https://openalex.org/I4210112601","display_name":"Ba\u011fc\u0131lar E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/0238k6k75","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210112601"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mustafa Hakan Din\u00e7kal","raw_affiliation_strings":["Bagcilar Education and Research Hospital, Istanbul,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bagcilar Education and Research Hospital, Istanbul,","institution_ids":["https://openalex.org/I4210112601"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.179,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.84961086,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"117","issue":"1","first_page":"21","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.4580000042915344,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.4580000042915344,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.2831999957561493,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.16590000689029694,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.9810000061988831},{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/heart-failure-with-preserved-ejection-fraction","display_name":"heart failure with preserved ejection fraction","score":0.9940000176429749},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.9259999990463257},{"id":"https://openalex.org/keywords/high-sensitivity-c-reactive-protein","display_name":"high-sensitivity C-reactive protein","score":0.9570000171661377},{"id":"https://openalex.org/keywords/e-a-ratio","display_name":"E/A ratio","score":0.9020000100135803},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9449999928474426},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.6029999852180481}],"concepts":[{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.9281461834907532},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.8841869831085205},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8344200849533081},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.8169879913330078},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8123553991317749},{"id":"https://openalex.org/C2776523773","wikidata":"https://www.wikidata.org/wiki/Q1093815","display_name":"Hyperhomocysteinemia","level":3,"score":0.7450094223022461},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.5549893975257874},{"id":"https://openalex.org/C111566952","wikidata":"https://www.wikidata.org/wiki/Q1303462","display_name":"Cardiac function curve","level":3,"score":0.4483371078968048},{"id":"https://openalex.org/C111815664","wikidata":"https://www.wikidata.org/wiki/Q1440693","display_name":"Framingham Heart Study","level":4,"score":0.4428720474243164},{"id":"https://openalex.org/C11783203","wikidata":"https://www.wikidata.org/wiki/Q5478027","display_name":"Framingham Risk Score","level":3,"score":0.39768072962760925},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.391408234834671},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2015891671180725}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020138","descriptor_name":"Hyperhomocysteinemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020138","descriptor_name":"Hyperhomocysteinemia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D054144","descriptor_name":"Heart Failure, Diastolic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054144","descriptor_name":"Heart Failure, Diastolic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D054144","descriptor_name":"Heart Failure, Diastolic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000320106","doi":"https://doi.org/10.1159/000320106","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000320106","pdf_url":null,"source":{"id":"https://openalex.org/S4210184113","display_name":"Cardiology","issn_l":"0008-6312","issn":["0008-6312","1421-9751"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology","raw_type":"journal-article"},{"id":"pmid:20881390","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20881390","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1965619583","https://openalex.org/W1974630582","https://openalex.org/W1977841860","https://openalex.org/W1979384626","https://openalex.org/W1986411601","https://openalex.org/W1989869058","https://openalex.org/W2006008619","https://openalex.org/W2038835550","https://openalex.org/W2047043096","https://openalex.org/W2050271477","https://openalex.org/W2062023215","https://openalex.org/W2070742041","https://openalex.org/W2077842562","https://openalex.org/W2085313576","https://openalex.org/W2086170960","https://openalex.org/W2098605555","https://openalex.org/W2109281287","https://openalex.org/W2120074697","https://openalex.org/W2124378690","https://openalex.org/W2132272026","https://openalex.org/W2152421807","https://openalex.org/W2155559652","https://openalex.org/W2159598848","https://openalex.org/W2163680613","https://openalex.org/W2165313350","https://openalex.org/W2167855252","https://openalex.org/W2170635325","https://openalex.org/W2323783182","https://openalex.org/W2323862874","https://openalex.org/W2332364831","https://openalex.org/W2491061016","https://openalex.org/W4229534512"],"related_works":["https://openalex.org/W4408299971","https://openalex.org/W2248332512","https://openalex.org/W3108522892","https://openalex.org/W2393480158","https://openalex.org/W1989869058","https://openalex.org/W2167855252","https://openalex.org/W2002282944","https://openalex.org/W2341132829","https://openalex.org/W3195593559","https://openalex.org/W2385122849"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Increased":[1],"homocysteine":[2],"(HCY)":[3],"levels":[4,44],"are":[5,237],"associated":[6,216],"with":[7,47,51,102,109,111,119,187,217,230],"an":[8,112],"increased":[9,17],"risk":[10],"of":[11,114,250],"cardiovascular":[12],"disease.":[13],"Plasma":[14],"HCY":[15,43,180],"is":[16,225],"in":[18,45,93,142,152,163,172,185,227],"chronic":[19],"heart":[20,49,74,144,165,188,228,251],"failure":[21,50,130,145,166,189,229],"(CHF)":[22],"patients,":[23],"and":[24,34,66,81,128,147,168,212,244],"previous":[25],"studies":[26,236],"suggest":[27,222],"that":[28,207,223],"hyperhomocysteinemia":[29,224],"causes":[30],"adverse":[31],"cardiac":[32],"remodeling":[33],"affects":[35],"pump":[36],"function.":[37],"We":[38,59],"aimed":[39],"to":[40,239],"evaluate":[41],"the":[42,87,143,153,164,173,247],"patients":[46,63,186],"diastolic":[48],"preserved":[52,103,231],"left":[53,121],"ventricular":[54,122],"ejection":[55,232],"fraction":[56],"(LVEF).":[57],"METHODS:":[58],"prospectively":[60],"studied":[61],"68":[62],"(39":[64],"females":[65],"29":[67],"males)":[68],"who":[69,85],"were":[70,131,182,214],"hospitalized":[71],"for":[72],"symptomatic":[73],"failure,":[75],"as":[76,78,107],"well":[77],"40":[79],"age-":[80],"sex-matched":[82],"healthy":[83],"subjects":[84],"comprised":[86],"control":[88,154,174],"group.":[89,155,175],"CHF":[90,101,110],"was":[91,105,137,159],"diagnosed":[92],"all":[94],"cases":[95,108],"based":[96],"on":[97,246],"Framingham":[98],"diagnostic":[99],"criteria.":[100],"LVEF":[104,113,158],"defined":[106],"50%":[115],"or":[116],"more.":[117],"Patients":[118],"regional":[120],"wall":[123],"motion":[124],"abnormalities,":[125],"atrial":[126],"fibrillation,":[127],"renal":[129],"excluded.":[132],"RESULTS:":[133],"The":[134,156,176],"mean":[135,157,177],"age":[136],"65.5":[138],"\u00b1":[139,149,161,170,191,196],"9.6":[140],"years":[141,151],"group":[146,167],"65.2":[148],"9.7":[150],"59.8":[160],"5.3":[162],"61.4":[169],"5.2":[171],"total":[178],"fasting":[179],"concentrations":[181],"significantly":[183],"higher":[184],"(16.9":[190],"5.27":[192],"\u03bcmol/l":[193],"vs.":[194],"10.15":[195],"3.49":[197],"\u03bcmol/l,":[198],"respectively;":[199],"p":[200],"<":[201],"0.001).":[202],"Multiple":[203],"regression":[204],"analysis":[205],"indicated":[206],"NT-proBNP,":[208],"hs-CRP,":[209],"E/A":[210],"ratio,":[211],"HbA1C":[213],"independently":[215],"hyperhomocysteinemia.":[218],"CONCLUSIONS:":[219],"Our":[220],"results":[221],"prevalent":[226],"fraction.":[233],"Larger":[234],"scale":[235],"needed":[238],"clarify":[240],"its":[241],"pathogenic":[242],"mechanisms":[243],"effects":[245],"natural":[248],"history":[249],"failure.":[252]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}