{"id":"https://openalex.org/W1993308024","doi":"https://doi.org/10.1620/tjem.130.63","title":"Cineventriculographic Analysis of Left Ventricular Dynamics during Sustained Handgrip Exercise","display_name":"Cineventriculographic Analysis of Left Ventricular Dynamics during Sustained Handgrip Exercise","publication_year":1980,"publication_date":"1980-01-01","ids":{"openalex":"https://openalex.org/W1993308024","doi":"https://doi.org/10.1620/tjem.130.63","mag":"1993308024","pmid":"https://pubmed.ncbi.nlm.nih.gov/7368207"},"language":"en","primary_location":{"id":"doi:10.1620/tjem.130.63","doi":"https://doi.org/10.1620/tjem.130.63","is_oa":true,"landing_page_url":"https://doi.org/10.1620/tjem.130.63","pdf_url":"https://www.jstage.jst.go.jp/article/tjem1920/130/1/130_1_63/_pdf","source":{"id":"https://openalex.org/S189069745","display_name":"The Tohoku Journal of Experimental Medicine","issn_l":"0040-8727","issn":["0040-8727","1349-3329"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310313307","host_organization_name":"Tohoku University","host_organization_lineage":["https://openalex.org/P4310313307"],"host_organization_lineage_names":["Tohoku University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku Journal of Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/tjem1920/130/1/130_1_63/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101144982","display_name":"Kozui Miyazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I112524849","display_name":"Yamagata University","ror":"https://ror.org/00xy44n04","country_code":"JP","type":"education","lineage":["https://openalex.org/I112524849"]},{"id":"https://openalex.org/I4210165438","display_name":"Yamagata University Hospital","ror":"https://ror.org/05gg4qm19","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210165438"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KOZUI MIYAZAWA","raw_affiliation_strings":["Department of Clinical Laboratory, Yamagata University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Laboratory, Yamagata University School of Medicine","institution_ids":["https://openalex.org/I112524849","https://openalex.org/I4210165438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042508329","display_name":"Takao Honna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAKAO HONNA","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012628492","display_name":"Takashi Haneda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAKASHI HANEDA","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":null,"display_name":"TORU ARAI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TORU ARAI","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108647104","display_name":"Toshiyuki Nakajima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TOSHIYUKI NAKAJIMA","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103791864","display_name":"Takuji Miura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAKUJI MIURA","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112307946","display_name":"Masaharu Kanazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"MASAHARU KANAZAWA","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"last","author":{"id":null,"display_name":"SACHIO ONODERA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"SACHIO ONODERA","raw_affiliation_strings":["Department of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.1485932,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"130","issue":"1","first_page":"63","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9491999745368958,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9491999745368958,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.040699999779462814,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/left-ventricular-dynamics","display_name":"left ventricular dynamics","score":0.8600000143051147},{"id":"https://openalex.org/keywords/handgrip-exercise","display_name":"handgrip exercise","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cineventriculography","display_name":"cineventriculography","score":0.9120000004768372},{"id":"https://openalex.org/keywords/left-ventricular-end-diastolic-volume","display_name":"left ventricular end-diastolic volume","score":0.8149999976158142},{"id":"https://openalex.org/keywords/left-ventricular-end-systolic-volume","display_name":"left ventricular end-systolic volume","score":0.9710000157356262},{"id":"https://openalex.org/keywords/stroke-volume","display_name":"stroke volume","score":0.9929999709129333},{"id":"https://openalex.org/keywords/ejection-fraction","display_name":"ejection fraction","score":1.0},{"id":"https://openalex.org/keywords/afterload","display_name":"afterload","score":0.7570000290870667},{"id":"https://openalex.org/keywords/frank-starling-mechanism","display_name":"Frank-Starling mechanism","score":0.8999999761581421},{"id":"https://openalex.org/keywords/cardiac-contraction","display_name":"cardiac contraction","score":0.6769999861717224},{"id":"https://openalex.org/keywords/cardiac-patients","display_name":"cardiac patients","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C48277249","wikidata":"https://www.wikidata.org/wiki/Q1406926","display_name":"Preload","level":3,"score":0.8619844913482666},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8328626155853271},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.815578818321228},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7407487630844116},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.6036354899406433},{"id":"https://openalex.org/C80461066","wikidata":"https://www.wikidata.org/wiki/Q1698533","display_name":"Stroke volume","level":4,"score":0.5968221426010132},{"id":"https://openalex.org/C123576724","wikidata":"https://www.wikidata.org/wiki/Q1299082","display_name":"Afterload","level":3,"score":0.5576310157775879},{"id":"https://openalex.org/C2781231445","wikidata":"https://www.wikidata.org/wiki/Q5319569","display_name":"Asynergy","level":5,"score":0.4974682629108429},{"id":"https://openalex.org/C21143770","wikidata":"https://www.wikidata.org/wiki/Q3366819","display_name":"End-diastolic volume","level":5,"score":0.49388986825942993},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.4280877113342285},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2504613697528839},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.19081971049308777},{"id":"https://openalex.org/C2778535784","wikidata":"https://www.wikidata.org/wiki/Q7281300","display_name":"Radionuclide ventriculography","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002306","descriptor_name":"Cardiac Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005082","descriptor_name":"Physical Exertion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007537","descriptor_name":"Isometric Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009040","descriptor_name":"Motion Pictures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016276","descriptor_name":"Ventricular Function","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1620/tjem.130.63","doi":"https://doi.org/10.1620/tjem.130.63","is_oa":true,"landing_page_url":"https://doi.org/10.1620/tjem.130.63","pdf_url":"https://www.jstage.jst.go.jp/article/tjem1920/130/1/130_1_63/_pdf","source":{"id":"https://openalex.org/S189069745","display_name":"The Tohoku Journal of Experimental Medicine","issn_l":"0040-8727","issn":["0040-8727","1349-3329"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310313307","host_organization_name":"Tohoku University","host_organization_lineage":["https://openalex.org/P4310313307"],"host_organization_lineage_names":["Tohoku University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku Journal of Experimental Medicine","raw_type":"journal-article"},{"id":"pmid:7368207","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7368207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku journal of experimental medicine","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1620/tjem.130.63","doi":"https://doi.org/10.1620/tjem.130.63","is_oa":true,"landing_page_url":"https://doi.org/10.1620/tjem.130.63","pdf_url":"https://www.jstage.jst.go.jp/article/tjem1920/130/1/130_1_63/_pdf","source":{"id":"https://openalex.org/S189069745","display_name":"The Tohoku Journal of Experimental Medicine","issn_l":"0040-8727","issn":["0040-8727","1349-3329"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310313307","host_organization_name":"Tohoku University","host_organization_lineage":["https://openalex.org/P4310313307"],"host_organization_lineage_names":["Tohoku University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku Journal of Experimental Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1993308024.pdf","grobid_xml":"https://content.openalex.org/works/W1993308024.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1968139181","https://openalex.org/W2009392253","https://openalex.org/W2034362223","https://openalex.org/W2050716802","https://openalex.org/W2051529869","https://openalex.org/W2056591900","https://openalex.org/W2069939957","https://openalex.org/W2083365891","https://openalex.org/W2085030402","https://openalex.org/W2087554823","https://openalex.org/W2087743295","https://openalex.org/W2094823107","https://openalex.org/W2467813525"],"related_works":["https://openalex.org/W2116434008","https://openalex.org/W7112277448","https://openalex.org/W2414898423","https://openalex.org/W2056591900","https://openalex.org/W2518349560","https://openalex.org/W7098744858","https://openalex.org/W7144792571","https://openalex.org/W2087554823","https://openalex.org/W2034362223","https://openalex.org/W2418102822"],"abstract_inverted_index":{"In":[0],"order":[1],"to":[2,166,175],"evaluate":[3],"the":[4,66,71,117,124,137,181,185,192],"effect":[5],"of":[6,27,36,110],"handgrip":[7,164],"on":[8],"left":[9,49,169],"ventricular":[10,50,170],"dynamics,":[11],"cineventriculography":[12],"was":[13,79],"performed":[14],"in":[15,65,70,77,85,99,116,123,129,139,173,178,180,191],"16":[16],"patients":[17],"with":[18,81,136],"heart":[19],"disease":[20],"and":[21,55,60,88,120,141,148],"5":[22],"normal":[23,67,118,182],"subjects":[24],"at":[25],"30%":[26],"maximal":[28],"voluntary":[29],"contraction.":[30],"No":[31],"patient":[32,72,125,193],"had":[33],"ventriculographic":[34],"evidence":[35],"asynergy":[37],"or":[38],"valve":[39],"regurgitation.":[40],"During":[41],"exercise,":[42],"left-ventricular":[43],"end-diastolic":[44],"volume":[45,52,58],"(LVEDV)":[46],"insignificantly":[47],"increased,":[48],"end-systolic":[51],"(LVESV)":[53],"decreased,":[54],"hence":[56],"stroke":[57],"(SV)":[59],"ejection":[61],"fraction":[62],"(EF)":[63],"rose":[64],"group,":[68,183],"while":[69,184],"group":[73,119],"a":[74,103],"similar":[75],"change":[76],"LVEDV":[78,97],"associated":[80],"increased":[82,98,115,160],"LVESV,":[83],"resulting":[84],"unchanged":[86,122],"SV":[87,140],"decreased":[89],"EF.":[90],"It":[91],"is":[92,188],"notable":[93],"that":[94,158],"during":[95,132],"exercise":[96,133],"both":[100],"groups,":[101],"despite":[102],"shortened":[104],"diastolic":[105],"filling":[106],"period.":[107],"Mean":[108],"velocity":[109],"fiber":[111],"shortening":[112],"(mean":[113],"VCF)":[114],"remained":[121],"group.":[126,194],"The":[127],"changes":[128],"mean":[130],"VCF":[131],"were":[134],"correlated":[135],"alterations":[138],"EF":[142],"(r=0.46,":[143],"p":[144,150],"less":[145,151],"than":[146,152],"0.05":[147],"r=0.90,":[149],"0.001),":[153],"respectively).":[154],"These":[155],"data":[156],"signify":[157],"an":[159,167,176],"afterload":[161],"induced":[162],"by":[163],"leads":[165],"enhanced":[168],"myocardial":[171],"contraction":[172],"addition":[174],"increase":[177],"preload":[179],"Frank-Starling":[186],"mechanism":[187],"mainly":[189],"utilized":[190]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}