{"id":"https://openalex.org/W1992936313","doi":"https://doi.org/10.1016/j.neulet.2006.11.035","title":"Involvement of the histaminergic system in renal sympathetic and cardiovascular responses to leptin and ghrelin","display_name":"Involvement of the histaminergic system in renal sympathetic and cardiovascular responses to leptin and ghrelin","publication_year":2006,"publication_date":"2006-12-13","ids":{"openalex":"https://openalex.org/W1992936313","doi":"https://doi.org/10.1016/j.neulet.2006.11.035","mag":"1992936313","pmid":"https://pubmed.ncbi.nlm.nih.gov/17166664"},"language":"en","primary_location":{"id":"doi:10.1016/j.neulet.2006.11.035","doi":"https://doi.org/10.1016/j.neulet.2006.11.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neulet.2006.11.035","pdf_url":null,"source":{"id":"https://openalex.org/S203050076","display_name":"Neuroscience Letters","issn_l":"0304-3940","issn":["0304-3940","1872-7972"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084794906","display_name":"Mamoru Tanida","orcid":"https://orcid.org/0000-0002-1620-7167","observed_orcids":["https://orcid.org/0000-0002-1620-7167"]},"institutions":[{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mamoru Tanida","raw_affiliation_strings":["Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan. mtanida@YMP-i.co.jp","Institute for Protein Research, Osaka University, Suita, Osaka 565-0871 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan. mtanida@YMP-i.co.jp","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Institute for Protein Research, Osaka University, Suita, Osaka 565-0871 Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019440724","display_name":"Hidekazu Kaneko","orcid":"https://orcid.org/0000-0002-1811-7069","observed_orcids":["https://orcid.org/0000-0002-1811-7069"]},"institutions":[{"id":"https://openalex.org/I73613424","display_name":"National Institute of Advanced Industrial Science and Technology","ror":"https://ror.org/01703db54","country_code":"JP","type":"government","lineage":["https://openalex.org/I73613424"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidekazu Kaneko","raw_affiliation_strings":["National Institute of Advanced Industrial Science and Technology, 1\u20131, Higashi, Tsukuba, Ibaraki 305\u20138566, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Advanced Industrial Science and Technology, 1\u20131, Higashi, Tsukuba, Ibaraki 305\u20138566, Japan","institution_ids":["https://openalex.org/I73613424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111748917","display_name":"Jiao Shen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405265182","display_name":"ANBAS Corp. (Japan)","ror":"https://ror.org/0436r2580","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265182"]},{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jiao Shen","raw_affiliation_strings":["ANBAS Project, Y.M.P.-International Corporation, Kita-ku, Osaka 531-0072, Japan","Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ANBAS Project, Y.M.P.-International Corporation, Kita-ku, Osaka 531-0072, Japan","institution_ids":["https://openalex.org/I4405265182"]},{"raw_affiliation_string":"Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102742057","display_name":"Katsuya Nagai","orcid":"https://orcid.org/0000-0002-6186-7754","observed_orcids":["https://orcid.org/0000-0002-6186-7754"]},"institutions":[{"id":"https://openalex.org/I4405265182","display_name":"ANBAS Corp. (Japan)","ror":"https://ror.org/0436r2580","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265182"]},{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuya Nagai","raw_affiliation_strings":["ANBAS Project, Y.M.P.-International Corporation, Kita-ku, Osaka 531-0072, Japan","Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ANBAS Project, Y.M.P.-International Corporation, Kita-ku, Osaka 531-0072, Japan","institution_ids":["https://openalex.org/I4405265182"]},{"raw_affiliation_string":"Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":null,"fwci":1.2213,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.74674157,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"413","issue":"1","first_page":"88","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.4032999873161316,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.4032999873161316,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.1436000019311905,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.10939999669790268,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histamine","display_name":"histamine","score":0.925000011920929},{"id":"https://openalex.org/keywords/histaminergic-system","display_name":"histaminergic system","score":0.9139999747276306},{"id":"https://openalex.org/keywords/renal-sympathetic-nerve-activity","display_name":"renal sympathetic nerve activity","score":0.8080000281333923},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.9610000252723694},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/ghrelin","display_name":"ghrelin","score":1.0},{"id":"https://openalex.org/keywords/histamine-h1-receptor","display_name":"histamine H1 receptor","score":0.9139999747276306},{"id":"https://openalex.org/keywords/histamine-h3-receptor","display_name":"histamine H3 receptor","score":1.0},{"id":"https://openalex.org/keywords/thioperamide","display_name":"thioperamide","score":0.9909999966621399},{"id":"https://openalex.org/keywords/diphenhydramine","display_name":"diphenhydramine","score":1.0},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"central nervous system","score":0.6399999856948853},{"id":"https://openalex.org/keywords/cardiovascular-regulation","display_name":"cardiovascular regulation","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C2778501154","wikidata":"https://www.wikidata.org/wiki/Q18349602","display_name":"Histaminergic","level":3,"score":0.9884501695632935},{"id":"https://openalex.org/C2778997900","wikidata":"https://www.wikidata.org/wiki/Q7784686","display_name":"Thioperamide","level":5,"score":0.9569627642631531},{"id":"https://openalex.org/C63180777","wikidata":"https://www.wikidata.org/wiki/Q288395","display_name":"Histamine H3 receptor","level":4,"score":0.794245183467865},{"id":"https://openalex.org/C1122143","wikidata":"https://www.wikidata.org/wiki/Q61233","display_name":"Histamine","level":2,"score":0.7337116599082947},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7116847634315491},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6790623068809509},{"id":"https://openalex.org/C2779357093","wikidata":"https://www.wikidata.org/wiki/Q422269","display_name":"Ghrelin","level":3,"score":0.5478992462158203},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.5184276103973389},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.46114474534988403},{"id":"https://openalex.org/C10335311","wikidata":"https://www.wikidata.org/wiki/Q309513","display_name":"Histamine H1 receptor","level":4,"score":0.420634925365448},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3747636675834656},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3461075723171234},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33980557322502136},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002319","descriptor_name":"Cardiovascular System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006632","descriptor_name":"Histamine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007276","descriptor_name":"Injections, Intraventricular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D036361","descriptor_name":"Peptide Hormones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054439","descriptor_name":"Ghrelin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neulet.2006.11.035","doi":"https://doi.org/10.1016/j.neulet.2006.11.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neulet.2006.11.035","pdf_url":null,"source":{"id":"https://openalex.org/S203050076","display_name":"Neuroscience Letters","issn_l":"0304-3940","issn":["0304-3940","1872-7972"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Letters","raw_type":"journal-article"},{"id":"pmid:17166664","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17166664","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W2289475","https://openalex.org/W48765218","https://openalex.org/W1964922357","https://openalex.org/W1965414505","https://openalex.org/W1975679472","https://openalex.org/W1995502712","https://openalex.org/W2004538736","https://openalex.org/W2042425697","https://openalex.org/W2072214837","https://openalex.org/W2077687762","https://openalex.org/W2085372550","https://openalex.org/W2092542705","https://openalex.org/W2094605937","https://openalex.org/W2103893515","https://openalex.org/W2149446586","https://openalex.org/W2170851290","https://openalex.org/W2190606111"],"related_works":["https://openalex.org/W1995502712","https://openalex.org/W2049115053","https://openalex.org/W2149446586","https://openalex.org/W2063176001","https://openalex.org/W2182821803","https://openalex.org/W1966537168","https://openalex.org/W2044044647","https://openalex.org/W2004538736","https://openalex.org/W2059979002","https://openalex.org/W2221625389"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}