{"id":"https://openalex.org/W1992928034","doi":"https://doi.org/10.1021/bi00328a031","title":"Phospholipid localization in the plasma membrane of Friend erythroleukemic cells and mouse erythrocytes","display_name":"Phospholipid localization in the plasma membrane of Friend erythroleukemic cells and mouse erythrocytes","publication_year":1985,"publication_date":"1985-03-01","ids":{"openalex":"https://openalex.org/W1992928034","doi":"https://doi.org/10.1021/bi00328a031","mag":"1992928034","pmid":"https://pubmed.ncbi.nlm.nih.gov/3859334"},"language":"en","primary_location":{"id":"doi:10.1021/bi00328a031","doi":"https://doi.org/10.1021/bi00328a031","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi00328a031","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113615575","display_name":"Andr\u00e9 Rawyler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Rawyler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038491896","display_name":"Peter H. van der Schaft","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. H. Van der Schaft","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025713708","display_name":"Ben Roelofsen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Roelofsen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109032210","display_name":"Jos A.F. Op den Kamp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. A. F. Op den Kamp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.284,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.78967871,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"24","issue":"7","first_page":"1777","last_page":"1783"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phospholipid-distribution","display_name":"phospholipid distribution","score":0.8859999775886536},{"id":"https://openalex.org/keywords/plasma-membrane","display_name":"plasma membrane","score":0.9110000133514404},{"id":"https://openalex.org/keywords/membrane-asymmetry","display_name":"membrane asymmetry","score":0.7179999947547913},{"id":"https://openalex.org/keywords/transbilayer-distribution","display_name":"transbilayer distribution","score":0.7879999876022339},{"id":"https://openalex.org/keywords/phosphatidylserine","display_name":"phosphatidylserine","score":0.8330000042915344},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.8970000147819519},{"id":"https://openalex.org/keywords/phosphatidylethanolamine","display_name":"phosphatidylethanolamine","score":0.9769999980926514},{"id":"https://openalex.org/keywords/phosphatidylinositol","display_name":"phosphatidylinositol","score":0.9850000143051147},{"id":"https://openalex.org/keywords/sphingomyelin","display_name":"sphingomyelin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/friend-erythroleukemic-cells","display_name":"Friend erythroleukemic cells","score":0.8849999904632568},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.8259999752044678},{"id":"https://openalex.org/keywords/phospholipase-a2","display_name":"phospholipase A2","score":0.7450000047683716},{"id":"https://openalex.org/keywords/phospholipase-c","display_name":"phospholipase C","score":0.9229999780654907},{"id":"https://openalex.org/keywords/sphingomyelinase-c","display_name":"sphingomyelinase C","score":0.9390000104904175},{"id":"https://openalex.org/keywords/phosphatidylcholine-transfer-protein","display_name":"phosphatidylcholine transfer protein","score":0.9810000061988831}],"concepts":[{"id":"https://openalex.org/C2781170229","wikidata":"https://www.wikidata.org/wiki/Q426095","display_name":"Phosphatidylethanolamine","level":5,"score":0.9153404235839844},{"id":"https://openalex.org/C2779637612","wikidata":"https://www.wikidata.org/wiki/Q2354337","display_name":"Phosphatidylserine","level":4,"score":0.9018865823745728},{"id":"https://openalex.org/C61322309","wikidata":"https://www.wikidata.org/wiki/Q423143","display_name":"Sphingomyelin","level":3,"score":0.8594973087310791},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.8105248808860779},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.792625904083252},{"id":"https://openalex.org/C2780610907","wikidata":"https://www.wikidata.org/wiki/Q2273248","display_name":"Phosphatidylinositol","level":3,"score":0.7279229164123535},{"id":"https://openalex.org/C2778597717","wikidata":"https://www.wikidata.org/wiki/Q420248","display_name":"Phospholipase C","level":3,"score":0.5889918804168701},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5234543681144714},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5113891959190369},{"id":"https://openalex.org/C12927208","wikidata":"https://www.wikidata.org/wiki/Q210430","display_name":"Phospholipase","level":3,"score":0.4523544907569885},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3749236762523651},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.336882621049881},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2903357446193695},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.042168885469436646},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.03630349040031433}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004915","descriptor_name":"Leukemia, Erythroblastic, Acute","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005450","descriptor_name":"Fluorescamine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005622","descriptor_name":"Friend murine leukemia virus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010740","descriptor_name":"Phospholipases","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/bi00328a031","doi":"https://doi.org/10.1021/bi00328a031","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi00328a031","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:3859334","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3859334","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.46810001134872437,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1036888712","https://openalex.org/W1505537700","https://openalex.org/W1582516167","https://openalex.org/W1968840233","https://openalex.org/W1970951117","https://openalex.org/W1977986845","https://openalex.org/W1979704489","https://openalex.org/W1984215815","https://openalex.org/W1997001075","https://openalex.org/W2005859080","https://openalex.org/W2006365322","https://openalex.org/W2011276095","https://openalex.org/W2011839942","https://openalex.org/W2016445477","https://openalex.org/W2020249413","https://openalex.org/W2021105020","https://openalex.org/W2031686611","https://openalex.org/W2035591072","https://openalex.org/W2045533903","https://openalex.org/W2049050946","https://openalex.org/W2049321216","https://openalex.org/W2054303473","https://openalex.org/W2056762714","https://openalex.org/W2070841245","https://openalex.org/W2070884121","https://openalex.org/W2078502987","https://openalex.org/W2087379708","https://openalex.org/W2088672032","https://openalex.org/W2091647374","https://openalex.org/W2093012266","https://openalex.org/W2116955854","https://openalex.org/W2141665680","https://openalex.org/W2168526937","https://openalex.org/W2179142653","https://openalex.org/W2186595494","https://openalex.org/W2416678542"],"related_works":["https://openalex.org/W1978577589","https://openalex.org/W2021105020","https://openalex.org/W1986962123","https://openalex.org/W2056762714","https://openalex.org/W1969383350","https://openalex.org/W203595356","https://openalex.org/W53281381","https://openalex.org/W2078854019","https://openalex.org/W2066151585","https://openalex.org/W1990198778"],"abstract_inverted_index":{"The":[0,26,61,196],"distribution":[1,166],"of":[2,9,13,51,91,95,110,144,149,158,167,182,199,204,208,212,217,222],"phospholipids":[3],"over":[4,88],"outer":[5,108,134,191,197],"and":[6,19,45,53,80,114,135,141,188,192,215,220],"inner":[7,123,136,193],"layers":[8,90,137],"the":[10,35,39,92,107,111,122,133,145,155,164,168,175,179,183,205,209,213,218,223],"plasma":[11,93,156,180],"membranes":[12],"Friend":[14,96,184],"erythroleukemic":[15],"cells":[16],"(Friend":[17],"cells)":[18],"mature":[20,159],"mouse":[21,160],"erythrocytes":[22,161],"has":[23],"been":[24,31],"determined.":[25],"various":[27],"techniques":[28,67],"which":[29],"have":[30],"applied":[32],"to":[33,70,84,103,117,173],"establish":[34],"phospholipid":[36,147,170],"localization":[37],"include":[38],"following:":[40],"phospholipase":[41,43],"A2,":[42],"C,":[44],"sphingomyelinase":[46],"C":[47],"treatment,":[48],"fluorescamine":[49],"labeling":[50],"phosphatidylethanolamine,":[52,79,210],"a":[54],"phosphatidylcholine":[55],"transfer":[56],"protein":[57],"mediated":[58],"exchange":[59],"procedure.":[60],"data":[62],"obtained":[63],"with":[64,75],"these":[65,127],"different":[66],"were":[68,82],"found":[69,83,102],"be":[71,85,104,118,174],"in":[72,106,121,178,190],"good":[73],"agreement":[74],"each":[76],"other.":[77],"Phosphatidylcholine,":[78],"phosphatidylinositol":[81],"distributed":[86],"symmetrically":[87],"both":[89],"membrane":[94,112,157,181,201],"cells.":[97],"In":[98],"contrast,":[99],"sphingomyelin":[100],"was":[101,130,225],"enriched":[105],"layer":[109,124,198],"(80-85%),":[113],"phosphatidylserine":[115,224],"appeared":[116,172],"present":[119],"mainly":[120],"(80-90%).":[125],"From":[126],"results,":[128],"it":[129],"calculated":[131],"that":[132,150,163],"accounted":[138],"for":[139],"46%":[140,187],"54%,":[142],"respectively,":[143],"total":[146,169],"complement":[148],"membrane.":[151],"Analogous":[152],"studies":[153],"on":[154],"showed":[162],"transbilayer":[165],"mass":[171],"same":[176],"as":[177],"cell,":[185],"namely,":[186],"54%":[189],"layers,":[194],"respectively.":[195],"this":[200],"contains":[202],"57%":[203],"phosphatidylcholine,":[206],"20%":[207],"85%":[211],"sphingomyelin,":[214],"42%":[216],"phosphatidylinositol,":[219],"none":[221],"present.(ABSTRACT":[226],"TRUNCATED":[227],"AT":[228],"250":[229],"WORDS)":[230]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}